Detection of Molecular Clouds in the PeVatron Candidate Source LHAASO J0341+5258 by the Nobeyama 45-m Radio Telescope by Naomi Tsuji, Shunya Takekawa, Kaya Mori, Alison Mitchell, Shuo Zhang, Priyadarshini Bangale, Stephen DiKerby, Tülün Ergin, Jooyun Woo, Samar Safi-Harb, Shinta Kasuya

“…We report a new CO observation survey of LHAASO J0341+5258, using the Nobeyama Radio Observatory 45-m telescope. …”
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Bispecific antibody targeting TROP2xCD3 suppresses tumor growth of triple negative breast cancer by Jing Wang, Lin Li, Huicheng Liu, Lili Bai, Liu Huang, Na Ning, Yijia Li, Xuejiao Dong, Qiuyang Du, Minghui Xia, Yufei Chen, Likun Zhao, Yanhu Li, Qingwu Meng, Yaqi Duan, Jie Ming, Andy Qingan Yuan, Xiang-Ping Yang

“…Immunofluorescent staining was performed to demonstrate the interactions between T cells with TNBC cells. The cytotoxicity of T cells against TNBC cell lines and primary tumor cells mediated by F7AK3 were determined in vitro. …”
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Adolescent vaccine introductions scoping review: A decade of insights from low- and middle-income countries (2013−2023) by Arman Majidulla, Amelia K. Gerste, Anurima Baidya, Onimitein Georgewill, Kirthini K. Muralidharan, Degu J. Dare, Joeri S. Buis, Michelle M. Gill, Julie A. Denison, Andrew D. Kerkhoff, Rupali J. Limaye

“…We included English full text articles which provided insights based on primary data collection into vaccine introductions for adolescents over the past ten years (i.e., 2013 onwards). …”
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Symptom Trajectories and Clinical Subtypes in Post–COVID-19 Condition: Systematic Review and Clustering Analysis by Mingzhi Hu, Tian Song, Zhaoyuan Gong, Qianzi Che, Jing Guo, Lin Chen, Haili Zhang, Huizhen Li, Ning Liang, Guozhen Zhao, Yanping Wang, Nannan Shi, Bin Liu

“…Clustering analysis was used to classify included studies into distinct clinical subtypes. …”
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Circulating long non-coding RNAs NKILA, NEAT1, MALAT1, and MIAT expression and their association in type 2 diabetes mellitus by Irfan Ahmad, Mohammed Alfaifi, Mirza Masroor Ali Beg, Ali Gaithan Alkhathami, Prakash C Joshi, Osama M Alshehri, Abdulrahman Manaa Alamri, Amit Kumar Verma, Mohammad Yahya Alshahrani

“…Serum analysis was carried out to determine differences in biochemical parameters. Recorded data were used to evaluate associations with expression of lncRNAs NF-kappaB interacting lncRNA (NKILA), nuclear enriched abundant transcript 1 (NEAT1), metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), and myocardial infarction-associated transcript (MIAT) in T2DM cases.Results Compared with healthy controls, patients with T2DM showed an overall increase in expression of lncRNAs NKILA, NEAT, MALAT1, and MIAT by 3.94-fold, 5.28-fold, 4.46-fold, and 6.35-fold, respectively. …”
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Predictive role of the Albumin-Bilirubin score in ICU patients with cirrhosis and sepsis: insights from a large retrospective cohort by Jianjun Wang, Pei Yang, Chuan Qin, Yongwei Huang, Zhaohui Hu, Ruizi Shi, Sirui Chen, Xi Chen, Hua Luo, Jianping Gong, Xintao Zeng, Decai Wang

“…Subgroup analyses were used to explore the associations between the ALBI scores and different patient populations. …”
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Genomic insights into genetic diversity and seed coat color change in common bean composite populations by Eva Plestenjak, Eva Plestenjak, Mohamed Neji, Lovro Sinkovič, Vladimir Meglič, Barbara Pipan

“…Population structure was analyzed using Fst, principal component analysis (PCA) and clustering. …”
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Development and Evaluation of a Patient–Family Caregiver Dyad mHealth Intervention for Heart Failure Self-Care: Quasi-Experimental Study by Youn-Jung Son, JiYeon Choi, Hyue Mee Kim, Hoyoun Won, Jong-Chan Youn, Sang-Wook Kim, Wang-Soo Lee, Jun Hwan Cho, Kyung‑Taek Park, Joonhwa Hong, Da-Young Kim

“…Adherence to self-care behaviors, family caregivers’ contributions to self-care behaviors, and health-related quality of life were evaluated. Data were collected using self-administered questionnaires at baseline and at 1 month, 3 months, and 6 months post enrollment. …”
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Identifying the Antecedents of Humble Leadership for Managers with a Meta-synthesis Approach by Tahereh Mohammadi, Adel Zahedbabelan, Ali Khaleghkhah, Hossein Taghavi Qarabulagh

“…Data were subjected to three-stage coding (open, axial, and selective) with the assistance of Maxqda 2020 software. …”
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New Symbiotic Stars from LAMOST DR10 Spectra and Multiband Photometry by Jing Chen, Liang Wang, Yin-Bi Li, Xiao-Xiao Ma, A-Li Luo, Zi-Chong Zhang, Ming-Yi Ding, Kai Zhang

“…Ultimately, we classified all nine as S-type SySts using the J − H versus H − K _s diagram. Additionally, based on multiband photometric data from GALEX, Gaia, Two Micron All Sky Survey, ALLWISE, and several X-ray catalogs, we found 12 accreting-only SySt (acc-SySt) candidates, characterized by concurrent ultraviolet and infrared excess and accretion process. …”
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CRISPR/Cas9 mutagenesis reveals an essential role of PI4KB in promoting growth and resisting hemorrhagic disease caused by GCRV-II infection in juvenile grass carp by Jie Zhang, Liqiang Zhang, Xiaoman Wu, Minhui Tao, Yang Chen, Mingxian Chang

“…Since the negative regulatory role of gcPI4KB in GCRV infection was confirmed by in vitro data, we performed gene editing of gcPI4KB in grass carp. …”
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Multi-omics driven biomarker discovery and pathological insights into Pseudomonas aeruginosa pneumonia by Zhiwei Lin, Mingshan Xue, Mingqing Lu, Shuang Liu, Yueting Jiang, Qianyue Yang, Honghui Cui, Xia Huang, Zeguang Zheng, Baoqing Sun

“…Methods We performed a comprehensive proteomic and metabolomic analysis on clinical samples from patients diagnosed with P. aeruginosa pneumonia, including both bronchoalveolar lavage fluid (BALF) and serum to capture local and systemic host responses. Data were analyzed using advanced statistical techniques to identify differentially expressed proteins and metabolites. …”
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<i>Achnatherum inebrians</i> Bacterial Communities Associated with <i>Epichloë gansuensis</i> Endophyte Infection Under Low-Concentration Urea Treatment: Links to Plant Growth and... by Yuanyuan Jin, Zhenjiang Chen, Kamran Malik, Chunjie Li

“…Overall, our results suggest that the E+ plants had more root forks and greater average root diameter compared to E− plants under the UN treatment. In a pot experiment using UN, data from 16S rRNA amplicon sequencing revealed that <i>E. gansuensis</i> endophyte infection significantly altered the bacterial community composition in shoot and root, and significantly increased Shannon (<i>p</i> < 0.001) and Chao 1 (<i>p</i> < 0.01) indexes. …”
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MS4A7 based metabolic gene signature as a prognostic predictor in lung adenocarcinoma by Yan Jiang, Zhengyu Shu, Lei Cheng, Lei Cheng, Haowei Wang, Taiping He, Liwen Fu, Chao Zhao, Xuefei Li, Weicheng Zeng, Weicheng Zeng

“…Given the promising prediction value of metabolism-related genes in LUAD, this study aims to explore the role of MS4A7, a member of the MS4A gene family, in LUAD prognosis and immune microenvironment dynamics.MethodsA prognostic signature for LUAD was developed using the LASSO-Cox regression algorithm with RNA-seq data from 500 LUAD patients in The Cancer Genome Atlas database. …”
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A qualitative study on dietary behaviors and nutritional management needs of patients with active systemic lupus erythematosus (系统性红斑狼疮活动期患者饮食行为与营养管理需求的质性研究)... by SONG Weiting (宋炜婷), LI Yuwei (李雨蔚), QIAO Caicai (乔彩彩), WANG Sa (王飒), XUE Fei (薛菲), WANG Yuzhen (王玉珍), MIAO Huali (苗华丽)

“…The key themes were extracted using thematic analysis. Results After organizing the interview data, three major themes were identified: the interactive influence of disease and nutrition, the lack of awareness and knowledge among patients and healthcare providers, and psychological and sociocultural factors. …”
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Evidence based consensus statements for digital tools to address youth mental health literacy by Stephana Julia Moss, Sonia Siddiqui, Cristina Zuniga Chacon, Cynthia Sriskandarajah, Maia Stelfox, Ben Gaunce, Micaela Harley, Stacie Smith, Sofia B. Ahmed, Kathryn Birnie, Donna Halperin, Scott Halperin, Christine Hampson, Jia Hu, Laura Leppan, Angie Nickle, Kristine Russell, Andrea Soo, May Solis, Henry T. Stelfox, Sharon Straus, Perri R. Tutelman, Quincy Wiele, Kirsten M. Fiest, Nicole Racine, Jeanna Parsons Leigh

“…The resulting design of the Youth MindTrack tool to support mental health literacy included four main interactive sections designed to be downloaded and completed by youth on a digital device. …”
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Monitoring spatiotemporal changes in global change drivers and their effects on semiarid woodlands and forests - fieldwork protocol [version 2; peer review: 2 approved] by Alice Nunes, Helena C. Serrano, Pedro Pinho, Adriana Principe, Juliana Monteiro, Silvana Munzi, Mana Gharun, Rocío Alonso, Rossella Guerrieri, Cristina Branquinho, Sami Ullah, Bernardo Rocha, Elena Vanguelova, Maria Alexandra Oliveira

“…After the practical experience in the field using these experiences, participants were divided into groups to analyze and discuss collected data together with trainers. …”
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eCBT-I dialogue system: a comparative evaluation of large language models and adaptation strategies for insomnia treatment by Xueying Bao, Xingyu Zhu, Dongren Yang, Hao Lou, Ruoyun Wang, Yutong Wu, Wenhui Li, Yu Xia, Li Zeng, Yingying Pan, Xiqin Wang, Xian Zhang, Cheng Ling, Youhui Ling, Yan Zhang, Qi Zhao, Mei Yang

“…The systematic fine-tuning method selection process and the confirmation of the optimal model not only improve the adaptability of the large language model in the CBT-I task, but also provide a useful paradigm for AI applications in medical subfields with resource constraints and difficulties in data collection, laying a solid foundation for more accurate and efficient digital CBT-I clinical practice in the future.…”
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Impaired sleep, depressive symptoms, and pain as determinants of physical activity and exercise intervention adherence: an exploratory analysis of a randomized clinical trial by Eija Kekkonen, Anette Hall, Riitta Antikainen, Satu Havulinna, Miia Kivipelto, Jenni Kulmala, Tiina Laatikainen, Teemu I. Paajanen, Shireen Sindi, Hilkka Soininen, Timo Strandberg, Jaakko Tuomilehto, Tiia Ngandu, Alina Solomon

“…Data on PA at baseline and at 2-years were available for 1100 participants. …”
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A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors by Paolo Romania, Loredana Cifaldi, Loredana Cifaldi, Paula Gragera, Valerio D’Alicandro, Matteo Caforio, Valentina Folgiero, Valeria Lucarini, Ombretta Melaiu, Ombretta Melaiu, Roberto Bei, Franco Locatelli, Franco Locatelli, Doriana Fruci

“…PLAC1-related gene expression and survival data were obtained from the TCGA database and analyzed using R. …”
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