Gene polymorphisms of IL-1β (C511T), IL-17A (G197A), IL-12B (A1188C), TNFα (G308A) and IL-4 (C589T) associated with threat of early reproductive losses by E. A. Tatarkova, A. R. Tuguz, A. A. Tsikunib, D. S. Shumilov, I. V. Smolkov, K. A. Rudenko, D. V. Muzhenya

“…Statistical analysis of experimental data was carried out by SPSS Statistical program 17.0. …”
Get full text

Impact of Sex on Infection Risk in Patients with Systemic Lupus Erythematosus by R. Borrelli, S. Nicola, F. Corradi, I. Badiu, L. Lo Sardo, N. Rashidy, A. Quinternetto, M. Mazzola, F. Meli, E. Saracco, I. Vitali, S. Negrini, L. Brussino

“…Model fit was evaluated using the Hosmer–Lemeshow test, and interactions between variables were tested. …”
Get full text

ImmuProgML: machine learning-based dissection of cancer-immune dynamics during tumor progression to improve immunotherapy by Hanxiao Zhou, Lan Mei, Qianyi Lu, Yakun Zhang, Yue Sun, Caiyu Zhang, Han Jiang, Jiajun Zhou, Xia Li, Yunpeng Zhang, Shangwei Ning

“…Methods We developed ImmuProgML framework by integrating multi-omics data and dynamic network biomarker (DNB) analysis to identify key pathways and critical stages in cancer progression, tested in melanoma and non-small cell lung cancer (NSCLC). …”
Get full text

Effectiveness and Feasibility of Digital Pulmonary Rehabilitation in Patients Undergoing Lung Cancer Surgery: Systematic Review and Meta-Analysis by Taiping Lu, Ting Deng, Yangyang Long, Jin Li, Anmei Hu, Yufan Hu, Li Ouyang, Huiping Wang, Junliang Ma, Shaolin Chen, Jiale Hu

“…MethodsA systematic review was conducted, retrieving data from 6 English and 4 Chinese databases from their inception to January 1, 2024. …”
Get full text

Identifying Shahid Sattari’s Strategic Leadership Competencies: Teachings for Public Managers by Naser Asgari

“…These materials were purposefully selected and analyzed using thematic analysis. To ensure reliability, the two-coder agreement method was employed to evaluate and confirm findings. …”
Get full text

Physical activity and internalization problems in middle school students: the chain mediating role of rumination thinking and peer acceptance by Kelei Guo, Shengyong Chen, Zhen Hui, Feng Guo, Jun Xiang, Dong Li

“…SPSS26.0 was used to analyze the data, followed by descriptive analysis, reliability analysis, Pearson correlation analysis, Harman single factor test and Bootstrap analysis. (1) Physical exercise was negatively correlated with internalizing problems (r = − 0.286), but the direct path between physical exercise and internalizing problems was not statistically significant (β = − 0.060, p > 0.05, CI [− 0.137, 0.018]); (2) Physical exercise was significantly negatively correlated with Rumination (β = − 0.174, p < 0.001, CI [− 0.255, − 0.094]) and significantly positively correlated with peer acceptance (β = 0.357, p < 0.001, CI [0.286, 0.429]). …”
Get full text

Graded Finiteness of Persian Complement Clauses Based on Landau's Minimalist view and Givon's Functionalist Approach by Foroozandeh Zardashti, Bahram Modarresi, Mohammad Mehdi Esmaaili

“…Materials and methodsIn this research, the data were collected through library research and analyzed using a descriptive-analytical approach within the framework of Landau's minimalism and Givón's functionalism. …”
Get full text

ANATOMICAL AND GENETIC PREDISPOSITION FOR CARIES IN PERMANENT DENTITION. REVIEW by K.A. Udaltsova, E.O. Pisarenko

“…Database PubMed Central® (PMC) was used as a source for literature review because of analogues studying lack among Ukrainian population. …”
Get full text

Multi-omics dissection of metabolic dysregulation associated with immune recovery in people living with HIV-1 by Lin-Yu Wan, Sin Man Lam, Hui-Huang Huang, Wen-Jing Cao, Xiang-Yi Cao, Xue-Meng Li, Li-Ping Zhang, Jia-Min Gao, Chao Zhang, Xing Fan, Yan-Mei Jiao, Guanghou Shui, Fu-Sheng Wang, Jin-Wen Song

“…The data were analyzed using the Mann–Whitney U-test, Kruskal–Wallis test, Spearman correlation, and LASSO regression analysis. …”
Get full text

Orchestrated desaturation reprogramming from stearoyl‐CoA desaturase to fatty acid desaturase 2 in cancer epithelial‐mesenchymal transition and metastasis by Zhicong Chen, Yanqing Gong, Fukai Chen, Hyeon Jeong Lee, Jinqin Qian, Jing Zhao, Wenpeng Zhang, Yamin Li, Yihui Zhou, Qiaobing Xu, Yu Xia, Liqun Zhou, Ji‐Xin Cheng

“…Specific desaturation activities were characterized through various isomer‐resolved lipidomics methods and sensitivity assays using desaturase inhibitors. In‐situ lipid profiling was conducted using multiplex stimulated Raman scattering imaging. …”
Get full text

LRP11 promotes stem-like T cells via MAPK13-mediated TCF1 phosphorylation, enhancing anti-PD1 immunotherapy by Zhishui Chen, Gang Chen, Li Chen, Xiangli Zhao, Lingjuan Sun, Zhibo Ma, Xiaosheng Tan, Yuhao Tu, Jingzeng Wang, Peixiang Lan

“…Molecular interactions and TCF1 status were examined using Western blotting. …”
Get full text

Polymorphisms in CYP3A5, CYP3A4, and ABCB1 genes: implications for calcineurin inhibitors therapy in hematopoietic cell transplantation recipients—a systematic review by Luiz Carlos da Costa-Junior, Luiz Carlos da Costa-Junior, Daniely Regina Freitas-Alves, Amanda Melo Leite Leão, Amanda Melo Leite Leão, Hayra de Andrade Vieira Monteiro, Rita de Cássia Barbosa da Silva Tavares, Maria Claudia Rodrigues Moreira, Maria Claudia Rodrigues Moreira, Marília Berlofa Visacri, Teresa de Souza Fernandez, Paulo Caleb Júnior de Lima Santos, Paulo Caleb Júnior de Lima Santos

“…Studies on non-human subjects, solid organ transplants, pharmacokinetic models, and drug interactions were excluded. Narrative synthesis was employed due to heterogeneity, and study quality was evaluated using the Newcastle–Ottawa Scale (NOS) and STREGA guidelines. …”
Get full text

Cognitive gains and cortical thickness changes after 12 weeks of resistance training in older adults with low and high risk of mild cognitive impairment: Findings from a randomized... by Simona Kušleikienė, Gal Ziv, Wouter A.J. Vints, Erika Krasinskė, Milda Šarkinaite, Orgesa Qipo, Ivan Bautmans, Uwe Himmelreich, Nerijus Masiulis, Vida J. Česnaitienė, Oron Levin

“…The Montreal Cognitive Assessment (MoCA) was used to stratify participants screened for high (< 26) or low (≥ 26) MCI risk. …”
Get full text

HLA variation associated with peanut allergy and anaphylaxis among non-Hispanic Black individuals by Baojun Wu, PhD, Mao Yang, MS, Donglei Hu, PhD, Ray Zhang, Bin Liu, PhD, MPH, Samantha Hochstadt, MS, David E. Lanfear, MD, MS, Jonathan Witonsky, MD, MAS, Rajesh Kumar, MD, MS, Jill A. Hollenbach, PhD, MPH, Esteban G. Burchard, MD, MPH, Elad Ziv, MD, L. Keoki Williams, MD, MPH, MBA

“…Four-digit resolution HLA allele calls were made using whole genome sequence data. Results: The cases consisted of 119 individuals with reported peanut allergy and 59 individuals with peanut-related anaphylaxis; the comparison group consisted of 2640 individuals without reported food allergy. …”
Get full text

The impact of mentoring relationships on professional identity formation in medical education: a systematic review by Lalit Kumar Radha Krishna, Nila Ravindran, Hannah Yi Fang Kwok, Xuan Yu Tan, Jasper Soh, Elizabeth Yong Mei Leong, Darius Wei Jun Wan, Tiat Yan Low, Aiden Wei-Jun Chan, Nicholas Chong Jin Lim, Yen Kit Ng, Arthena Anushka Thenpandiyan, Jun Rey Leong, Adele Yi Dawn Lim, Elaine Li Ying Quah, Leia Ning Tse, Sriram PL, Sri Priyanka Rajanala, Jun Kiat Lua, Varsha Rajalingam, Victoria Jia En Fam, Ranitha Govindasamy, Nur Amira Binte AbdulHamid, Crystal Lim, Eng Koon Ong, Shin Wei Sim, Stephen Mason, Simon Yew Kuang Ong

“…Related themes and categories were combined using the SEBA methodology. Results 248 articles were identified across four databases and snowballing of key articles. …”
Get full text

Prognostic Value of a Joint K‐PD Model With Tumor Size Dynamics and CA‐125 Kinetics in Recurrent Ovarian Cancer Patients: BOLD Phase II GINECO Study by Aurore Carrot, Pauline Corbaux, Olivier Colomban, Coriolan Lebreton, Laurence Gladieff, Olivier Tredan, Frédéric Selle, Cyril Abdeddaim, Alexandra Leary, Véronique D'Hondt, Coraline Dubot, Thibaut Reverdy, Benoit You, Gilles Freyer

“…The prognostic value of KELIM‐B and KELIM‐joint was assessed using univariate/multivariate analyses (PFS/OS). …”
Get full text

Effects of Step Length and Stride Variation During Forward Lunges on Lower-Extremity Muscle Activity by Rafael F. Escamilla, Irwin S. Thompson, Robert Asuncion, Jacqueline Bravo, Tiffany Chang, Taylor Fournier, Hannah Garcia, Emily Hockenbery, Kyle Nagasawa, Joan Ozor, Hannah Snoeberger, Kevin E. Wilk, Mario Bizzini

“…Background: The forward lunge is a closed-chain weight-bearing multi-joint exercise simulating the activities of daily living, such as walking or stair climbing, which mainly activates hip, knee, and ankle musculature and is also used by athletes and other individuals to train lower-extremity musculature. …”
Get full text

Understanding the interplay of Caesarean delivery and genetic influences on intelligence and anxiety traits in offspring findings from genome-wide association studies by Bita Fallahpour, Mahsa Danaei, Maryam Yeganegi, Fatemeh Jayervand, Sepideh Azizi, Heewa Rashnavadi, Seyed Alireza Dastgheib, Reza Bahrami, Amirhossein Shahbazi, Ali Masoudi, Kazem Aghili, Fatemeh Nematzadeh, Hossein Neamatzadeh

“…The inclusion criteria focused on original research articles published in English, excluding studies involving non-human subjects or without empirical data. The quality of the studies was assessed using a modified STROBE checklist adapted for GWAS. …”
Get full text

Electronic Implementation of Patient-Reported Outcome Measures in Primary Health Care: Mixed Methods Systematic Review by Maxime Sasseville, Wilfried Supper, Jean-Baptiste Gartner, Géraldine Layani, Samira Amil, Peter Sheffield, Marie-Pierre Gagnon, Catherine Hudon, Sylvie Lambert, Eugène Attisso, Steven Ouellet, Mylaine Breton, Marie-Eve Poitras, Pierre-Henri Roux-Lévy, James Plaisimond, Frédéric Bergeron, Rachelle Ashcroft, Sabrina T. Wong, Antoine Groulx, Jean-Sébastien Paquette, Natasha D'Anjou, Sylviane Langlois, Annie LeBlanc

“…These studies, primarily conducted in the United States (n=9, 41%) and Canada (n=8, 36%), covered various chronic diseases and used diverse ePROM tools, predominantly mobile apps (n=9, 41%). …”
Get full text

Mosquito-based detection of retroviruses and arboviruses in Senegal: expanding the scope of xenosurveillance by Marie Henriette Dior Ndione, El Hadji Ndiaye, Madeleine Dieng, Babacar Diouf, Safietou Sankhé, Diawo Diallo, Mouhamed Kane, Ndeye Marie Sene, Maimouna Mbanne, Faty Amadou Sy, Seynabou Mbaye Ba Souna Diop, Serge Freddy Moukaha Doukanda, Amadou Alpha Sall, Ousmane Faye, Ndongo Dia, Scott C. Weaver, Oumar Faye, Mawlouth Diallo, Gamou Fall, Alioune Gaye, Moussa Moise Diagne

“…Blood-fed mosquitoes were pooled and subjected to RNA extraction and metagenomic sequencing using Illumina NextSeq550. Sequencing data were analyzed with CZ-ID and BLAST for viral identification. …”
Get full text