USP14 inhibition by degrasyn induces YAP1 degradation and suppresses the progression of radioresistant esophageal cancer by Fang Yuan, Juan Xu, Lingmei Xuan, Chan Deng, Wei Wang, Rong Yang

“…We also used transplantation tumor mouse model to investigate the course of the cancer cell growth. …”
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Investigating patient engagement associations between a postdischarge texting programme and patient experience, readmission and revisit rates outcomes by Farzan Sasangohar, Claudia García, Roberta L Schwartz, Courtenay Bruce, Theresa Pinn-Kirkland, Adam Meyers, Emmanuel Javaluyas, John Osborn, Sayali Kelkar, Lindsey Bruchhaus, Kristen McLaury, Katherine Sauceda, Karen Carr, Lee Ann Arabie, Terrell Williams, Gail Vozzella, Tariq Nisar

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Assessing the quality of care in primary health care facilities in all municipalities in Kosovo 2016–2023 by Astrid M. Knoblauch, Astrid M. Knoblauch, Sarah Rajkumar, Sarah Rajkumar, Robert Canavan, Robert Canavan, Qamile Ramadani, Ariana Bytyçi Katanolli, Shegë Bahtiri, Debra Stevenson, Debra Stevenson, Debra Stevenson, Merita Stavileci Mustafa, Nicu Fota, Nicu Fota, Nicu Fota, Jana Gerold, Jana Gerold

“…Three quality of care studies were conducted with the aim of measuring progress in PHC and NCD management.MethodsThree facility-based, cross-sectional studies were conducted in 2016, 2018 and 2023 across 12, 20, and 38 selected municipalities in Kosovo, respectively. Data were collected on PHC infrastructure, provider-patient interactions, and patient outcomes using standardized assessments, observational tools, and exit interviews.ResultsThe overall infrastructure score improved from 56% in 2016 to 68% in 2023. …”
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Environmental and food security implications of livestock abortions and calf mortality: a case study in Kenya and Tanzania by Endale B. Gurmu, Endale B. Gurmu, Barend Bronsvoort, Barend Bronsvoort, Elizabeth A. J. Cook, Elizabeth A. J. Cook, Felix Lankester, Felix Lankester, Şeyda Özkan, Peri K. Rosenstein, George Semango, Nick Wheelhouse, Nick Wheelhouse, Andreas Wilkes, Claudia Arndt

“…A life cycle assessment using the Global Livestock Environmental Assessment Model-interactive (GLEAM-i) examines GHG sources and potential tradeoffs. …”
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Neonatal and 3-month cerebrovascular oxygenation, stability, and extraction in congenital heart disease versus control infants by Nhu N. Tran, Jodie K. Votava-Smith, John C. Wood, Joanne Yip, Andrew Pham, Mary-Lynn Brecht, Panteha Hayati Rezvan, Anthony R. Colombo, Philippe Friedlich, Ken M. Brady, Bradley S. Peterson

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Growing empathy through art therapy, life story, and relationships: experiential learning in adult day services by L. Blake Peeples, L. Blake Peeples, L. Blake Peeples, Benjamin C. Thompson, Benjamin C. Thompson, Jackie B. Tucker, Jackie B. Tucker, LaDerrick Smith, Amy Brown, Keisha D. Carden, Keisha D. Carden, Keisha D. Carden, Anne Halli-Tierney, Angel C. Duncan, Neelum T. Aggarwal, Jessica Y. Allen, Rebecca S. Allen, Rebecca S. Allen, Rebecca S. Allen, Daniel C. Potts, Daniel C. Potts, Daniel C. Potts

“…Intergenerational relationships are fostered with people with dementia through art therapy and life story/narrative at a community-based adult day services center.MethodsIn this sequential mixed methods study, quantitative data were collected via electronic surveys of students in this course compared with students in didactic introductory psychology or psychology and aging courses. …”
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A one year longitudinal study of cortical myelination changes following pediatric mild traumatic brain injury by Jessica R. McQuaid, Tracey V. Wick, Josef Ling, Andrew B. Dodd, Divyasree Sasi Kumar, Upasana Nathaniel, Samuel D. Miller, Vadim Zotev, Harm J. van der Horn, John P. Phillips, Richard A. Campbell, Robert E. Sapien, Timothy B. Meier, Andrew R. Mayer

“…., grey matter) myelination is not yet understood, especially for interactions with neurodevelopment. The current study examined the impact of pmTBI on cortical myelination relative to healthy controls (HC) by estimating myelin content using the T1w/T2w ratio method. …”
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The nasal mycobiome of individuals with allergic rhinitis and asthma differs from that of healthy controls in composition, structure and function by Marcos Pérez-Losada, Marcos Pérez-Losada, Eduardo Castro-Nallar, Eduardo Castro-Nallar, Jenaro García-Huidobro, José Laerte Boechat, José Laerte Boechat, Luis Delgado, Luis Delgado, Luis Delgado, Tiago Azenha Rama, Tiago Azenha Rama, Manuela Oliveira, Manuela Oliveira

“…This study contributes valuable fungal data and results to understand the relationships between the nasal mycobiome and allergy-related conditions. …”
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An Integrated Approach Utilizing Single-Cell and Bulk RNA-Sequencing for the Identification of a Mitophagy-Associated Genes Signature: Implications for Prognostication and Therapeu... by Yuke Zhang, Li Ding, Zhijin Zhang, Liliang Shen, Yadong Guo, Wentao Zhang, Yang Yu, Zhuoran Gu, Ji Liu, Aimaitiaji Kadier, Jiang Geng, Shiyu Mao, Xudong Yao

“…Stratifying patients by molecular subtypes may identify those who could benefit from immunotherapy. <b>Methods</b>: We used single-cell and bulk RNA sequencing data from GEO and TCGA databases. …”
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IL-18R supported CAR T cells targeting oncofetal tenascin C for the immunotherapy of pediatric sarcoma and brain tumors by Jessica Wagner, Stephen Gottschalk, Giedre Krenciute, Jinghui Zhang, Shannon Lange, Jason Chiang, Liqing Tian, Deanna Langfitt, Peter Vogel, Heather Sheppard, Timothy I Shaw, Jorge Ibanez, Selene C Koo, Elizabeth Wickman, Meifen Lu, Matthew Bell, S Scott Perry, Raghuvaran Shanmugam

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Multidisciplinary analysis of the prognosis and biological function of NUBPL in gastric cancer by Luqian Liu, Fengyu Zhang, Jiaye Yu, Pingping Dong, Jing Deng, Weiwei Liu, Xinlei Cao, Juanjuan Huang, Xiaoming Lin, Xiangyang Xue

“…Meanwhile, the ESTIMATE algorithm was used for immune infiltration analysis and prediction of immunotherapy response, and the Genomics of Drug Sensitivity in Cancer (GDSC) database was utilized for the drug sensitivity analysis of NUBPL. …”
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Examining the evolution and impact of OTC vending machines in Global Healthcare Systems by Ammar Abdulrahman Jairoun, Sabaa Saleh Al-Hemyari, Moyad Shahwan, Sahab Alkhoujah, Faris El-Dahiyat, Ammar Ali Saleh Jaber, Sa'ed H. Zyoud

“…Data analysis included bibliometric indicators such as publication counts, citation trends, and co-authorship networks, which were visualized using VOSviewer software (version 1.6.20) to highlight key research themes and collaboration patterns. …”
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Short-term air pollution exposure and risk of respiratory pathogen infections: an 11-year case-crossover study in Guangzhou, China by Wenhan Cao, Huimin Huang, Zhenglin Chang, Zhiman Liang, Haiyang Li, Zhangkai Cheng, Baoqing Sun

“…Logistic regression was used to assess the effect of air pollutant exposure included in the equation on the risk of respiratory pathogen infection. …”
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Kinematic Analysis of z = 4.3 Galaxies in the SPT2349–56 Protocluster Core by Aparna Venkateshwaran, Axel Weiss, Nikolaus Sulzenauer, Karl Menten, Manuel Aravena, Scott C. Chapman, Anthony Gonzalez, Gayathri Gururajan, Christopher C. Hayward, Ryley Hill, Cassie Reuter, Justin S. Spilker, Joaquin D. Vieira

“…In this paper, we study the kinematics of the galaxies found in the core of SPT2349−56 using high-resolution (1.55 kpc spatial resolution at z = 4.303) redshifted [C ii ] 158 μ m data. …”
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MO-GCN: A multi-omics graph convolutional network for discriminative analysis of schizophrenia by Haiyuan Wang, Runlin Peng, Yuanyuan Huang, Liqin Liang, Wei Wang, Baoyuan Zhu, Chenyang Gao, Minxin Guo, Jing Zhou, Hehua Li, Xiaobo Li, Yuping Ning, Fengchun Wu, Kai Wu

“…The methodology of machine learning with multi-omics data has been widely adopted in the discriminative analyses of schizophrenia, but most of these studies ignored the cooperative interactions and topological attributes of multi-omics networks. …”
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Exposome study for allergic diseases in children: Rationale and design of ECHO-COCOA study by Song-I Yang, Hosub Im, Yanghee Kim, Hyo-Bin Kim, Jeong-Hyun Kim, Jeonghun Yeom, Hyun Ju Yoo, Mi Jeong Kim, Hoon Je Seong, Hea Young Oh, Yong Joo Park, Mi-Jin Kang, Seung-Hwa Lee, Hwan-Cheol Kim, Sung-Ok Kwon, Kyung-Sook Lee, Yee-Jin Shin, Jisun Yoon, Eom ji Choi, Youn Ho Shin, Dong In Suh, Ji Soo Park, Kyung Won Kim, Kangmo Ahn, Jihyun Kim, Soo-Jong Hong

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Human papillomavirus 16 mitigates Sneathia vaginalis-induced damage to cervical keratinocytes by Phoebe V. Bridy, Jasmine C. Cruz, Jada L. Covington, Taharah I. Islam, Catherine E. Hadley, Kayla Tran, Rachel Fry, Bradley A. Sheffield, Myrna Serrano, Gregory A. Buck, Jinlei Zhao, Katherine Y. Tossas, Craig Meyers, Iain M. Morgan, Claire D. James, Kimberly K. Jefferson

“…Recent microbiome studies demonstrate an association between S. vaginalis and human papillomavirus (HPV) within the female reproductive tract, suggesting that HPV and S. vaginalis could interact in some way within this shared niche. We analyzed 16S rRNA survey and HPV typing data from our Vaginal Human Microbiome Project and found, in agreement with other reports, that S. vaginalis was associated with HPV infection. …”
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A Coherent Approach-Based Fine-Tuning of Segment Anything Model Plus Watershed Algorithm for Instance Segmentation of Mitochondria in Electron Microscopy Images by Zahra Faska, Lahbib Khrissi, Imadeddine Mountasser, Khalid Haddouch, Nabil El Akkad, Samah Alshathri, Walid El-Shafai

“…Increasingly available ultrastructural data from a continuously growing diversity of experimental conditions are driving new opportunities for fruitful neuroscientific hypotheses tested in intracellular compartments such as the nanoscale roles of, e.g., the mitochondria. …”
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Single-cell profiling of SLC family transporters: uncovering the role of SLC7A1 in osteosarcoma by Yan Liao, Junkai Chen, Hao Yao, Ting Zheng, Jian Tu, Weidong Chen, ZeHao Guo, Yutong Zou, Lili Wen, Xianbiao Xie

“…Methods The single-cell sequencing data from GSE152048 and GSE162454, along with RNA-seq from the TARGET and GSE21257 cohorts, were utilized for the analysis in this study. …”
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RBIS regulates ribosome biogenesis to affect progression in lung adenocarcinoma by Hongyu Pan, Li Liao, Siwei Xu, Yujian Xu, Wenjun Chai, Xiaoli Liu, Jing Li, Yue Cao, Lei Sun, Qian Liu, Mingxia Yan

“…We conducted co-immunoprecipitation (Co-IP) assays followed by Western blot analysis to identify potential proteins interacted with RBIS. The half maximal inhibitory concentration (IC50) was used for evaluating the chemosensitivity of lung cancer cells to gemcitabine. …”
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