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  1. 18441

    Effects of physical exercise on metabolic syndrome in psychotic disorders: A systematic review with meta-analysis of randomized controlled trials by Arantxa Ancín-Osés, Mikel Izquierdo, Manuel J. Cuesta, Mikel L. Sáez de Asteasu

    Published 2025-01-01
    “…Risk of bias was evaluated using the Cochrane RoB-2 tool. Data were pooled using random-effects models in Comprehensive Meta-Analysis and JASP. …”
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  2. 18442

    Deciphering molecular landscape of breast cancer progression and insights from functional genomics and therapeutic explorations followed by in vitro validation by Bushra Khan, Rowaid Qahwaji, Mashael S. Alfaifi, Tanwir Athar, Abdullah Khan, Mohammad Mobashir, Ibraheem Ashankyty, Khalid Imtiyaz, Areej Alahmadi, M. Moshahid A. Rizvi

    Published 2024-11-01
    “…The objective of our study was to elucidate the molecular mechanisms underlying the transition of Ductal Carcinoma In Situ (DCIS) to Invasive Ductal Carcinoma (IDC), with a particular focus on hub genes and potential therapeutic agents. Using Weighted Gene Co-expression Network Analysis (WGCNA), we built a comprehensive network combining clinical and phenotypic data from both DCIS and IDC. …”
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  3. 18443

    Mfsd2a suppresses colorectal cancer progression and liver metastasis via the S100A14/STAT3 axis by Linfeng Sun, Xiangdong Li, Yuhao Xiao, Wenjie Yu, Xuyang Chen, Ziyi Wang, Nan Xia, Xuejiao Chen, Minhao Chen, Haoliang Zhu, Jie Li, Jie Wei, Sheng Han, Liyong Pu

    Published 2025-01-01
    “…Methods In this study, we conducted a survival analysis of Mfsd2a in colorectal cancer using data from the GEPIA and GEO databases, and examined the expression differences between primary tumor (PT) and liver metastasis (LM). …”
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  4. 18444

    Associations of blood-based biomarkers of neurodegenerative diseases with mortality, cardio- and cerebrovascular events in persons with chronic coronary syndrome by Valerie Lohner, Laura Perna, Ben Schöttker, Robert Perneczky, Hermann Brenner, Ute Mons

    Published 2025-02-01
    “…Methods: We used data from a cohort of persons with CCS for whom major adverse events were recorded over a follow-up of 20 years. …”
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  5. 18445

    Spatio-temporal dynamics of Isoberlinia-dominated woodlands in disturbance-prone landscapes over 15 years by Shègoun Eudes Idjigbèrou, Eméline Sêssi Pélagie Assédé, Séverin Biaou, Gérard Nounagnon Gouwakinnou, Armand Kuyema Natta, Samadori Sorotori Honoré Biaou

    Published 2025-06-01
    “…We calculated species richness and density for sapling and adult trees, and estimated two main variables: potential productivity using water deficit as a proxy, and disturbance intensity using logging rate. …”
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  6. 18446

    Deep Multi-Modal Skin-Imaging-Based Information-Switching Network for Skin Lesion Recognition by Yingzhe Yu, Huiqiong Jia, Li Zhang, Suling Xu, Xiaoxia Zhu, Jiucun Wang, Fangfang Wang, Lianyi Han, Haoqiang Jiang, Qiongyan Zhou, Chao Xin

    Published 2025-03-01
    “…MDSIS-Net extracts intra-modality features using transfer learning in a multi-scale fully shared convolutional neural network and introduces an innovative information-switching module. …”
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  7. 18447

    Baseline-dependent network reactivity to visual input in children with autism spectrum disorder: a magnetoencephalography study by Tetsu Hirosawa, Tetsu Hirosawa, Daiki Soma, Masuhiko Sano, Masafumi Kameya, Yuko Yoshimura, Yuko Yoshimura, Sumie Iwasaki, Sanae Tanaka, Mitsuru Kikuchi, Mitsuru Kikuchi

    Published 2025-07-01
    “…MEG signals were mapped to 68 cortical regions using the Desikan–Killiany atlas, and functional connectivity was assessed using the phase lag index across five frequency bands (delta, theta, alpha, beta, and gamma). …”
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  8. 18448

    Determination of high-grade serous ovarian cancer stem cell-based subtypes and prognostic model and identification of highly expressed VSIG4 and STAB1 in macrophages by Huijuan Wu, Dan Li, Lu Sun, Hualin Song, Ke Wang

    Published 2025-07-01
    “…Macrophage subpopulations were identified using single cell data, and pseudo-time analysis revealed the changes of macrophages during cell state transition. …”
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  9. 18449

    Tracing Coherent Gas Structures in the Central Region of the Starburst Galaxy NGC 253. II. Gas Excitation and Star Formation by Ryotaro Konishi, R. Enokiya, Y. Fukui, K. Tachihara, K. Muraoka, T. Onishi

    Published 2025-01-01
    “…Molecular gas in the central region of the starburst galaxy NGC 253 is complicated because of the combination of different gas kinematics, including stellar feedback, noncircular motions, and magnetic activity. In paper I, we used the latest multitransition, multi-isotope CO-line data sets obtained with the Atacama Large Millimeter/submillimeter Array to classify the molecular gas within the central 850 pc in radius into 28 coherent structures, and we proposed a three-dimensional geometric structure for the gas in the central region of this galaxy. …”
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  10. 18450
  11. 18451

    Association of Personal Care and Consumer Product Chemicals with Long-Term Amenorrhea: Insights into Serum Globulin and STAT3 by Ziyi Li, Xue Song, Daniel Abdul Karim Turay, Yanling Chen, Guohong Zhao, Yingtong Jiang, Kun Zhou, Xiaoming Ji, Xiaoling Zhang, Minjian Chen

    Published 2025-03-01
    “…Various statistical models for robustness tests and mediation analysis were used to explore associations with long-term amenorrhea and the role of serum globulin. …”
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  12. 18452

    Natural Product Identification and Molecular Docking Studies of Leishmania Major Pteridine Reductase Inhibitors by Moses N. Arthur, George Hanson, Emmanuel Broni, Patrick O. Sakyi, Henrietta Mensah-Brown, Whelton A. Miller, Samuel K. Kwofie

    Published 2024-12-01
    “…A library of 1463 natural compounds from AfroDb and NANPDB, prefiltered based on Lipinski’s rules, was used to screen against the LmPTR1 target. The X-ray structure of LmPTR1 complexed with NADP and dihydrobiopterin (Protein Data Bank ID: 1E92) was identified to contain the critical residues Arg17, Leu18, Ser111, Phe113, Pro224, Gly225, Ser227, Leu229, and Val230 including the triad of residues Asp181-Tyr194-Lys198, which are critical for the catalytic process involving the reduction of dihydrofolate to tetrahydrofolate. …”
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  13. 18453

    Depth distributions of soil temperature: Seasonal sensitivity and simulation across dryness/wetness conditions by Yining Wang, Jiefeng Wu, Jian-yun Zhang, Tiesheng Guan, Guoqing Wang, Junliang Jin, Zhenlong Wang

    Published 2025-07-01
    “…Using long-term monthly observations (1966–2022) from the Wudaogou National Comprehensive Hydrological Observation Station in Anhui Province, China, we analyzed the soil temperature at depths of 0–320 cm paired with meteorological data. …”
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  14. 18454

    CYFIP2: potential pancreatic cancer biomarker and immunotherapeutic target by Cong Xiao, Xiaojuan Zhang, Bobo Hou, Ping Wan, Zhenjun Cao, Xuefeng Rao

    Published 2024-12-01
    “…Methods The Cancer Genome Atlas (TCGA), Genotype-Tissue Expression (GTEx) database, CELL and GEO databases were utilized to explore the distribution of the CYFIP2 gene in human cancers. Data were analyzed using a variety of web-based platforms and software such as R (4.3.2), UCSC, MethSurv, Cytoscape (v3.10.2), UALAND, STRING, TISIDB, Harmonizome 3.0, TIMER 2.0, TCIA and TIDE. …”
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  15. 18455

    Bioinformatics-driven identification of key non-invasive prognostic biomarkers in hepatocellular carcinoma by Muhammad-Redha Abdullah-Zawawi, Muhammad Irfan Abdul Jalal, Shing Cheng Tan, Loscheni Varma, Nur Alyaa Afifah Md Shahri, Mira Farzana Mohamad Mokhtar, Ryia Illani Mohd Yunos, Nurul Syakima Ab Mutalib, Rahman Jamal

    Published 2025-04-01
    “…We subsequently developed a network of protein–protein interactions and established the densely interconnected clusters (core genes) underlying the network using these differentially expressed genes (DEGs). …”
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  16. 18456

    3-O Sulfated Heparan Sulfate (G2) Peptide Ligand Impairs the Infectivity of <i>Chlamydia muridarum</i> by Weronika Hanusiak, Purva Khodke, Jocelyn Mayen, Kennedy Van, Ira Sigar, Balbina J. Plotkin, Amber Kaminski, James Elste, Bajarang Vasant Kumbhar, Vaibhav Tiwari

    Published 2025-07-01
    “…<b>Methodology:</b> To rule out the possibility that host cell 3-O sulfated heparan sulfate (3-OS HS) plays a significant role in <i>C. muridarum</i> entry, a Chinese hamster ovary (CHO-K1) cell model lacking endogenous 3-OST-3 was used. In addition, we further tested the efficacy of the phage-display-derived cationic peptides recognizing heparan sulfate (G1 peptide) and the moieties of 3-O sulfated heparan sulfate (G2 peptide) against <i>C. muridarum</i> entry using human cervical adenocarcinoma (HeLa 229) and human vaginal epithelial (VK2/E6E7) cell lines. …”
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  17. 18457

    Understanding Gender-Specific Daily Care Preferences: Topic Modeling Study by Kyungmi Woo, Se Hee Min, Aeri Kim, Subin Choi, Gregory L Alexander, Terrence O’Malley, Maria D Moen, Maxim Topaz

    Published 2025-05-01
    “…ObjectiveThis study aims to identify and analyze the key themes and daily care preferences from unstructured adult text narratives with a focus on uncovering gender-specific variations. MethodsThis study used 4350 deidentified, unstructured textual data from MyDirectives (MyDirectives, Inc), an interactive online platform. …”
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  18. 18458

    Dog-assisted interventions to support health and wellbeing: a national survey of current practice in England by Emily Shoesmith, Sophie S. Hall, Evgenia Riga, Daniel S. Mills, Selina Gibsone, Dean McMillan, Qi Wu, Chris Clarke, Elena Ratschen

    Published 2025-08-01
    “…IntroductionIn England, dog-assisted interventions (DAIs) are increasingly used to support the health and wellbeing of individuals with mental and physical health conditions. …”
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  19. 18459
  20. 18460

    Rethinking of the Ornament in rural house (Case study: Ovan village in Qazvin) by Mohammad Yaser Mousapour

    Published 2018-09-01
    “…Qualitative research generally refers to research whose findings have not been obtained through statistical processes and for quantitative purposes. The data of this type of research is collected through observation, interviewing or oral interactions, and focuses on the meanings and contributions of the participants. ‎…”
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