Succinylation-related molecular activities in cancer: metabolic adaptations, immune landscape, and prognostic significance in colorectal cancer by Zhihang Jiang, Zhihang Jiang, Xiaoqing Li, Xiaoqing Li, Long Hu, Zheng Jiang

“…Succinylation scores were calculated using Gene Set Variation Analysis (GSVA). The interactions between succinylation scores, immune infiltration, tumor microenvironment, tumor mutational burden, and immunotherapy response were assessed. …”
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Divergent effects of short-term and continuous anthropogenic noise exposure on Western Bluebird parental care behavior by Kerstin Ozkan, Jordan M. Langley, Jason W. Talbott, Nathan J. Kleist, Clinton D. Francis

“…The effect of the playback type interacted with the effect of the order in which trials were presented. …”
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BET Protein Inhibition Relieves MDSC-Mediated Immune Suppression in Chronic Lymphocytic Leukemia by Erin M. Drengler, Audrey L. Smith, Sydney A. Skupa, Elizabeth Schmitz, Eslam Mohamed, Dalia El-Gamal

“…<b>Conclusions</b>: Altogether, these data support BET inhibition as a useful therapeutic approach to reverse MDSC-mediated immune suppression in CLL.…”
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Defining Public Health Transformation: A Scoping Review by Violet Phooko, Kuhlula Maluleke, Sebueng Ramatsokotla, Thato Serite, Kabelo Kgarosi, Funeka Sokudela, Tivani Mashamba‐Thompson

“…The quality of the included studies was assessed using the 2018 version of the mixed method appraisal tool. …”
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Flavonoid compound from Forsythia suspensa leaves inhibits adenovirus infection related to cell cycle based on UHPLC-Q-Exactive-Orbitrap/MS and experimental validation by Lingling Wang, Shuanshan Ren, Xingming Ma, Yanliu Li, Yongyong Zheng, Ling Li, Luhong Cao

“…An integrated analysis of GEO data revealed 990 adenovirus-associated DEGs, with network pharmacology and functional enrichment analyses further demonstrating FSL flavonoids’ preferential targeting of cell cycle regulators. …”
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Evaluation of mechanical properties and color stability of 3D-printed denture base materials following two surface treatments by Eymen Izzettinoglu, Erdal Eroglu

“…Statistical analysis of the data was performed using descriptive and analytical methods, with a significance level set at α = 0.05. …”
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Barriers and facilitators to sports participation in autistic Europeans: insights from a large-scale questionnaire survey by Célia Ruffino, Nicolas Gueugneau, Sidney Grosprêtre, Sidney Grosprêtre

“…This study seeks to provide an overview of sports participation among autistic Europeans and identify factors influencing their engagement in physical activities.MethodUsing an online questionnaire translated into five languages, data was collected from 540 respondents across several European countries. …”
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Behavioral tests for the assessment of social hierarchy in mice by Hao Zheng, Dantong Chen, Zilong Zhong, Ziyi Li, Meng Yuan, Zhenkun Zhang, Xiaoping Zhou, Guohui Zhu, Hongwei Sun, Lin Sun

“…This review summarizes the primary behavioral methods used to assess social dominance in mice, evaluates their applicability and limitations, and discusses potential improvements. …”
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Affective disorders and chronic inflammatory conditions: analysis of 1.5 million participants in Our Future Health by Daniel J Smith, Katie F M Marwick, Arish Mudra Rakshasa-Loots, Duncan Swiffen, Christina Steyn

“…Odds of experiencing affective disorders, calculated using logistic regression models, were significantly higher in this group compared with the general population (OR (95% CI) = 1.86 (1.82 to 1.90), p&lt;0.001), and these odds remained elevated when adjusting for the effects of age, sex, ethnicity (OR=1.75 (1.71 to 1.79), p&lt;0.001) and additionally, for household income, parental history of affective disorders, chronic pain status and frequency of social interactions (OR=1.48 (1.44 to 1.52), p&lt;0.001).Conclusions Overall, the risk of affective disorders among people living with autoimmune conditions was nearly twice that of the general population.Clinical implications Although the observational design of this study does not allow for direct inference of causal mechanisms, this analysis of a large national dataset suggests that chronic exposure to systemic inflammation may be linked to a greater risk for affective disorders. …”
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PCA Weight Determination-Based InSAR Baseline Optimization Method: A Case Study of the HaiKou Phosphate Mining Area in Kunming, Yunnan Province, China by Weimeng Xu, Jingchun Zhou, Jinliang Wang, Huihui Mei, Xianjun Ou, Baixuan Li

“…Additionally, the GACOS (Generic Atmospheric Correction Online Service) atmospheric correction product is applied to further enhance data quality. Taking the Haikou Phosphate Mine area in Kunming, Yunnan, as the study area, surface deformation information was extracted using the SBAS-InSAR technique, and the spatiotemporal characteristics of subsidence were analyzed. …”
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Joint and independent associations of dietary vitamin intake and prevalence of cardiovascular disease in chronic kidney disease subjects: a cross-sectional analysis by Guoqing Wang, Guoqing Wang, Luojun Huang, Luojun Huang, Wenwen Yue, Wenwen Yue, Jun Feng, Jun Feng

“…Additionally, we examined the co-exposure of nine dietary vitamins, defined as their concurrent intake, and evaluated the potential additive or interactive effects of co-exposure of nine dietary vitamins on CVD risk in CKD patients using Bayesian kernel machine regression (BKMR) and weighted quantile sum (WQS) regression.ResultsFinally, 2,203 CKD participants (weighted n = 27,120,429) were included, and 622 had CVD, with a CVD prevalence of 28.2%. …”
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Lungs volume status and oxygen transport in patients with coronary artery disease with various types of comorbidity before and after coronary artery bypass grafting by B. I. Geltser, E. A. Sergeev, V. N. Kotelnikov, K. A. Fogelevich, A. A. Silaev

“…The analysis of volume and hemodynamic monitoring data demonstrated the heterogeneity of their changes during CABG and one day after with different comorbidity profile. …”
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Family involvement along the care continuum for small and sick newborns – attitudes and skills of healthcare providers in Ghana by Christina Schuler, Faith Agbozo, Emmanuel Bansah, Richard Owusu, George Edward Ntow, Barbara Preusse-Bleuler, Riccardo E. Pfister

“…The survey instruments included the standardized and validated instruments ‘Family Importance in Care - Nurses’ attitudes’ (FINC-NA) and ‘Family Nursing Practice Scale’ (FNPS), which measure healthcare providers’ attitudes and skills in working with families, alongside four open-ended questions. Quantitative data were analyzed using descriptive statistics, while answers to open-text components were categorized thematically. …”
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Pharmacy Preparedness in Disaster Management in Pediatric Emergency Department (PED) by Dr Faiza Usman

“…Methodology: A quantitative analysis was used to gather data from EMR (Electronic medical record). …”
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A multi-omics exploration of PPARG activation in colon cancer: kinases featuring a PPRE sequence within regulatory regions by Pritha Saha, Palaniyandi Ravanan, Priti Talwar

“…Peak calling analysis from ChIP-seq data identified 14,000 to 34,000 binding sites for PPARG across different experimental conditions. …”
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New insights on Galectin-9 expression in cancer prognosis: An updated systemic review and meta-analysis. by Chun Yan So, Yusong Li, Kwan Ting Chow

“…Galectin-9 (Gal-9) has gained increasing attention in recent years in the field of cancer immunology. Its interactions with various immune cell types in the tumor microenvironment influence tumor progression, making it a novel target for immunotherapy. …”
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Particle flux–gradient relationships in the high Arctic: emission and deposition patterns across three surface types by T. Mathes, H. Guy, H. Guy, J. Prytherch, J. Kojoj, I. Brooks, S. Murto, P. Zieger, B. Wehner, M. Tjernström, A. Held

“…Near-surface particle and sensible heat fluxes were measured using the gradient method during the ARTofMELT Arctic Ocean Expedition 2023. …”
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Metagenomic and phylogenetic analyses reveal gene-level selection constrained by bacterial phylogeny, surrounding oxalate metabolism in the gut microbiota by Sromona D. Mukherjee, Mangesh Suryavanshi, John Knight, Dirk Lange, Aaron W. Miller

“…In conservative genome-based estimates, over 30% of gut microbial species harbored at least one oxalate-handling gene, with the specific pathways used dependent on bacterial phylum. Co-occurrence analyses revealed interactions between specialist genes that can metabolize oxalate or its by-products, but not multi-functional genes that can act in more than one oxalate-related pathway. …”
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Research on carbon compensation zoning guided by major function zones: A case study of the Yangtze River Delta region by Rui Shen, Yinan Yang, Jialong Xu, Li Wang, Yuhang Jiang, Yujing Xie, Yuan Wang

“…To address this gap, we developed a “carbon source- carbon sequestration ” quantification model using multi-source data and employed a hierarchical analysis approach to examine carbon budget inequities in the Yangtze River Delta (YRD) region at both grid and county scales. …”
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Comparative transcriptome analysis reveals key genes and signaling pathways mediated by salicylic acid in potato by Aie Chen, Beini Zhang, Huijie Wang, Jiangqing Wang, Ji Wei, Yuxin Jia, Hongyang Wang

“…Functional validation using virus-induced gene silencing demonstrated that NbPAL1 and NbPAL2 are essential regulators of SA biosynthesis. …”
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