Single-cell transcriptomics analysis reveals dynamic changes and prognostic signature in tumor microenvironment of PDAC by Yongsheng Li, Zhilong Ding, Tingxin Cheng, Yihuai Hu, Fei Zhong, Shiying Ren, Shiyan Wang

“…This study aims to elucidate the dynamic changes in the TME during PDAC progression and develop a prognostic model using single-cell RNA sequencing (scRNA-seq) data. …”
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Experimental Study on Bond Fatigue Between Carbon Fiber-Reinforced Polymer Bars and Seawater–Sea Sand Concrete Under Seawater Immersion and Dry–Wet Cycle Conditions by Fu Yang, Weiquan Gan, Bingsan Chen, Jiangchuan Wu, Shiwen Yuan

“…However, excessively high stresses may lead to bond fatigue failures. Using experimental data and existing fatigue bond–slip constitutive models, a customized model for CFRP bars in SWSSC was developed. …”
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Identification of key ferroptosis genes in hepatocellular carcinoma and type 2 diabetes mellitus through bioinformatics analysis by Jinjin Zhou, Yage Shi, Yulun Jian, Yuhan Li, Wenya Yu, Wei Mu, Yang Ge

“…To explore the complex interactions between ferritin deposition, T2DM, and HCC, we performed bioinformatics analysis on publicly available gene expression data and identified 23 differentially expressed genes (DEGs) that are commonly expressed in both T2DM and HCC. …”
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Study on Pressure Oscillation Characteristic of Steam Low-velocity Jet under Seawater Condition by Study on Pressure Oscillation Characteristic of Steam Low-velocity Jet under Seawater Condition

“…In order to address the research gap in steam-seawater interactions and evaluate the feasibility of using seawater as a coolant in marine nuclear power systems, the pressure oscillation characteristics of steam low-velocity jet in seawater have been investigated. …”
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Gut Microbiome dysbiosis and immune activation correlate with somatic and neuropsychiatric symptoms in COVID-19 patients by Paula L. Scalzo, Austin G. Marshall, Sirena Soriano, Kristen Curry, Mario Dulay, Timea Hodics, Eamonn M. M. Quigley, Todd J. Treangen, María M. Piskorz, Sonia Villapol

“…Gut microbiome profiling was performed using full-length 16 S rRNA gene sequencing to evaluate microbial diversity and composition. …”
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Determinants of improvement trends in health workers' compliance with outpatient malaria case-management guidelines at health facilities with available "test and treat" commodities... by Beatrice Amboko, Kasia Stepniewska, Lucas Malla, Beatrice Machini, Philip Bejon, Robert W Snow, Dejan Zurovac

“…Association between 31 determinants and improvement trends in five outpatient compliance outcomes were examined using interactions between each determinant and time in multilevel logistic regression models and reported as an adjusted odds ratio of annual trends (T-aOR).…”
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Evaluating the influence of anti-PD-1 immunotherapy combined with IMRT on thyroid dysfunction in nasopharyngeal carcinoma by Liqianqi Chen, Zihuang Li, Xianming Li, Shihai Wu, Long Gong, Gang Xu, Shanyi Chen, Yucong Zhang

“…Data collected included smoking status, BMI, presence of thyroid nodules, staging, treatment modality, thyroid mean dose (Dmean), percentage of thyroid volume receiving more than x Gy, pituitary mean dose (Dmean), and TSH and FT4 levels per cycle. …”
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Culturomics of the pig tonsil microbiome identifies new species and an untapped source of novel antimicrobials by Isabela Maria Fernandes de Oliveira, Simen Fredriksen, Marcela Fernández Gutiérrez, Hermie J. M. Harmsen, Jos Boekhorst, Peter van Baarlen, Jerry M. Wells

“…Here, we describe a large collection of representative bacterial species from the tonsil surface biofilm and used genome mining and in vitro assays to assess their potential as probiotics to reduce infections by S. suis and other pathogens. …”
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Transcriptome analyses for revealing leaf abscission of Cyclocarya paliurus stem segments in vitro by Gaoyin Wu, Zhongcheng Peng, Qiuying Li, Xiang Zhang, Shuanggui Geng, Shuang Wang, Enrong Lu, Yingying Liu, Congjun Yuan, Xiaoli Wei, Yingliang Liu

“…The emerged leaves of C. paliurus stem segments were cultured for 22 days (T0) in vitro; leaves at 27 days (T1) and leaves that had fallen after ≥ 32 days (T2) were used as materials for analysis of the physiological characteristics and transcriptome data. …”
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Pleiotrophin promote glioma proliferation and invasion by enhancing NF-κB/SLUG mediated epithelial–mesenchymal transition by Hong-Xing Ye, Chao Zhang, Long-Yuan He, Ping Lan, Feng Wang, Ren-Ya Zhan, Xiu-Jue Zheng

“…Methods The expression levels of PTN in glioma samples were analyzed using data from The Cancer Genome Atlas (TCGA) and the Chinese Glioma Genome Atlas (CGGA). …”
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Roles of Single Nucleotide Polymorphisms in the SLC6A2 Gene in the Risk of Vasovagal Syncope Among Children in Eastern China: A Case‐Control Study by Minmin Wang, Meng Li, Haizhao Zhao, Xiaoyue Liu, Qingyu Kong, Cuifen Zhao, Baomin Li

“…Five single nucleotide polymorphisms (SNPs) in the SLC6A2 gene (rs2242446, rs168924, rs2397771, rs5564, and rs5569) were genotyped using TaqMan assays. Clinical and hematological data were analyzed alongside genetic information. …”
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Digital Technologies in Urban Regeneration: A Systematic Literature Review from the Perspectives of Stakeholders, Scales, and Stages by Xiaer Xiahou, Xingyuan Ding, Peng Chen, Yuchong Qian, Hongyu Jin

“…With the fast advancement of digital technologies such as artificial intelligence (AI), Internet of Things (IoT), and big data, these technologies have extensively penetrated various dimensions of urban regeneration, from planning and design to implementation and post-operation management, providing new possibilities for improving urban regeneration efficiency and quality. …”
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Development of a core outcome set for pharmacological interventions in osteoporosis among patients with diabetes mellitus: an international consensus study protocol by Chao Wei, Chao Wei, Xiaobin Wang, Zubing Mei, Zubing Mei, Jing Li

“…Patients with DM are at increased risk of developing osteoporosis due to complex pathophysiological interactions between glucose metabolism and bone health. …”
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Effects of Climate, Soil, Topography and Disturbance on Liana Prevalence by Emma J. Mackintosh, Catherine E. Waite, Francis E. Putz, Marion Pfeifer, Chengrong Chen, Zhongming Lan, Sophie Brennan, Andrew R. Marshall

“…., rattans) stems ≥ 1 cm DBH were measured and environmental data were collected on climate, soil and topography. …”
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Effect of Chemically Modified Biowaste-Low Density Polyethylene Waste Composites for Sorption of Heavy Metals in Soil Samples collected at Waste Dumpsite in Uvwie Local Government... by K. A. Ibe, B. Ati

“… The objective of this paper was to evaluate the effect of chemically modified biowaste-low density polyethylene waste composites prepared in a 1:1 and 1:2 ratios for sorption of heavy metals in soil samples collected at waste dumpsite in Uvwie Local Government Area of Delta State, Nigeria using appropriate standard techniques. Data obtained show reduction of values of metal concentration across board, before and after treatment with sorbents. …”
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The Dentin Microbiome: A Metatranscriptomic Evaluation of Caries-Associated Bacteria by Simone G. de Oliveira, Rodrigo Jardim, Nelson Kotowski, Alberto M. R. Dávila, Hélio R. Sampaio-Filho, Karina G. S. Ruiz, Flávio H. B. Aguiar

“…<b>Methods:</b> Samples from six patients (three healthy and three decayed teeth) were analyzed using the Illumina NovaSeq 2000 platform, with data processed through the SAMSA2 pipeline for taxonomic and functional annotation. …”
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Experience of Aging in the Ngäbe-Buglé Community in Coto Brus, Costa Rica: A Qualitative Study by Melissa Rallo, Nicholas Leahy, Alexis Vetack, Hima Konduru, Shania Bailey, Lillianna Pedersen, Christine Wan, Wendel Mora, Virginia Rowthorn, Shailvi Gupta, Carlos Faerron Guzmán

“…Thematic analysis was used to examine participants’ responses to understand their experiences with aging. …”
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Fertilization for Growth or Feeding the Weeds? A Deep Dive into Nitrogen’s Role in Rice Dynamics in Ecuador by Cristhian Fernando Sánchez-Sabando, Adriana Beatriz Sánchez-Urdaneta, Fernando David Sánchez-Mora, Gary Eduardo Loor-Escobar, Barlin O. Olivares

“…Weed incidence was higher in Los Ríos, dominated by grasses (55.28%), while Cyperaceae (46.27%) prevailed in Guayas. The data analysis included non-parametric tests to identify significant treatment effects, debiased sparse partial correlations (DSPCs) to reveal key agronomic interactions, and principal component analysis (PCA) to identify influential traits, ensuring robust and normalized interpretations. …”
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Extracellular Vesicle Mitochondrial DNA Levels Are Associated With Chronic Kidney Disease and Mitochondrial Haplogroup in Obese Individuals by Jaida E. Morgan, Nicole Noren Hooten, Nicolle A. Mode, Ngozi Ezike, Alan B. Zonderman, Michele K. Evans

“…In our longitudinal analyses using data from both visit 1 and visit 2, individuals who developed CKD had lower EV mtDNA levels. …”
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The potential ecological collapse of the seed dispersal network in an insular high mountain: Teide National Park by Manuel Nogales, Sara Beatriz Mendes, Beatriz Rumeu, Patricia Marrero, Javier Romero, María Guerrero-Campos, Ángel Mallorquín, Omar Trujillo, Carlos Sánchez, Pablo Vargas

“…The current network was built using field data collected in 2020–2021 and complemented with published records. …”
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