DTIAM: a unified framework for predicting drug-target interactions, binding affinities and drug mechanisms by Zhangli Lu, Guoqiang Song, Huimin Zhu, Chuqi Lei, Xinliang Sun, Kaili Wang, Libo Qin, Yafei Chen, Jing Tang, Min Li

“…Abstract Accurate and robust prediction of drug-target interactions (DTIs) plays a vital role in drug discovery but remains challenging due to limited labeled data, cold start problems, and insufficient understanding of mechanisms of action (MoA). …”
Get full text

Development of interactive-based civic education encyclopedia learning media to improve Pancasila student profiles by Nadya Putri Saylendra, Erwin Susanto, MSW Sona Minasya, Fani Kardina, Karna Januar

“…Methods for gathering data using a questionnaire. The employed data analysis techniques include deductive analysis, inductive analysis, reliability testing, validity testing, normalcy testing, homogeneity testing, independent samples mean testing, and hypothesis testing. …”
Get full text

Food-drug interactions: Modelling knowledge and attitude among healthcare professionals at the Ho Teaching Hospital. by Donatus Wewura Adongo, David Adedia, Augustine Tandoh, Hilda Amekyeh, Killian Asampana Asosega, Charles Kwaku Benneh, Eli Yao Lawluvi, Inemesit Okon Ben, Abigail Hohoayi, Ebenezer Wiafe, Jones Ofori-Amoah, Salifu Nanga, Eric Woode

“…<h4>Methodology</h4>A cross-sectional survey of 300 HCPs, including medical doctors, pharmacists, nurses, midwives, and dietitians, was conducted using a self-administered questionnaire. Data were analyzed using Kruskal-Wallis tests, logistic regression models and path analysis.…”
Get full text

Prevalence of drug interactions and its related factors in patients with epilepsy referred to Razi Hospital in Birjand by Azin Seifi, Kobra Naseri, Abbas Ali Ramazani, Melika Ramezani, Razieh Avan

“…The Chi-square, Fisher's tests, and logistic regression were used for data analysis. Results: The results showed that 154 patients (51%) were women in this study. …”
Get full text

Simulation of oak early life history and interactions with disturbance via an individual-based model, SOEL. by Kenneth F Kellner, Robert K Swihart

“…The model connects acorn survival, acorn dispersal, germination, seedling growth, and seedling survival submodels based on empirical data with an existing gap model (JABOWA). Using SOEL, we assessed the sensitivity of several metrics of oak regeneration to different parameters associated with early oak life history. …”
Get full text

Prediction of depression risk in middle-aged and elderly Cardiovascular-Kidney-Metabolic syndrome patients by social and environmental determinants of health: an interpretable mach... by Xinyi Xu, Xinru Li, Xiyan Li, Benli Xue, Xiao Zheng, Shujuan Xiao, Lingli Yang, Xinyi Zhang, Chengyu Chen, Ting Zheng, Yuyang Li, Yanan Wang, Jianan Han, Haoran Wu, Mengjie Zhang, Yanming Liao, Siyi Bai, Nan Zeng, Chichen Zhang

“…Conclusions A depression risk prediction model for middle-aged and elderly CKM patients was developed based on the CHARLS longitudinal data from 2011 to 2015. The SHAP framework was used to provide machine learning model explanations. …”
Get full text

COMPARATIVE CHARACTERISTIC OF THE POSITION OF INTERACTION OF STUDENTS – FUTURE MEDICAL WORKERS AND SPECIALISTS OF PSYCHOLOGICAL AND PEDAGOGICAL SUPPOR by I. I. Koryagina, V. G. Maralov, V. A. Sitarov

“…The set of theoretical and empirical methods based on the principles of general scientific methodology was used in the research: analysis, synthesis, generalization of source materials corresponding to the stated topic; testing, questioning, data collection, statistical processing of data. …”
Get full text

Proses Pembelajaran Melalui Interaksi Edukatif Dalam Pendidikan Islam by Rahmat Rifai Lubis, Media Gusman

“…(Library Studies), where the data sources used are books, or research journals related to Educational Interaction. …”
Get full text

The Role of Numerical Methods in the Sensitivity Analysis of a Density Parameter in a Passivation Rate Interaction by EN Ekaka-a, EO Chukwuocha, NM Nafo

“…Two numerical methods of studying sensitivity analysis of physiochemical interaction data are developed. This mathematical technique is used to investigate the extent of the sensitivity of the density parameter over a time interval. …”
Get full text

Relaxation and Thermal Conductivity of Hot and Thermal Quasiparticles and Fermi Liquid Interactions in d-wave Superconductors by H. Rabani

Get full text

Current insights and trends in atopic dermatitis and microbiota interactions: a systematic review and bibliometric analysis by Zhongsong Zhang, Zhongsong Zhang, Rong Wang, Mao Li, Mao Lu

“…This article uniquely integrates a systematic review with bibliometric analysis to map the research landscape of AD and microbiota interactions, offering a comprehensive synthesis of trends and future directions.MethodsWe conducted a bibliometric analysis using the Web of Science Core Collection, retrieving 1,196 English-language articles and reviews published between 2009 and 2024, employing a detailed search strategy targeting AD and microbiota-related terms. …”
Get full text

THERMODYNAMIC STUDIES OF THE INTERACTION OF SODIUM N-DODECYL, SULPHATE WITH CALF - THYMUS WISTONE H3

“…and 3 7 ?c .T he binding data have been used to obtain the Gibbs free energy of interaction using a theoretical model of the Wyman binding potential; and the enthalpy of interaction from the temperature dependence of theequilibriumconstantsfronr theVan't Hoff re1ation.The enthalpy of interaction of H3 and SDS is exothermic in some buffer solutions which is in marked contrast to other histone - SDS complexes, The entropy of initial interaction of H3 and SDS is negative in some other buffer solutions with increasing binding of SDS, the entropy becomes positive.…”
Get full text

Interaction in Online Tutoring Sessions: An Opportunity to Knit English Language Learning in a Blended Program by Rosa Alejandra Medina Riveros

“…Students' surveys, chat transcriptions and tutor's journals were used to collect data. The results showed how language itself, the methodology of the course, reflection upon learning, and social and personal issues made up the conversational topics prevailing in these sessions. …”
Get full text

Multi-omics analysis of host-microbiome interactions in a mouse model of congenital hepatic fibrosis by Mengfan Jiao, Ye Sun, Zixing Dai, Xiaoxue Hou, Xizhi Yin, Qingling Chen, Rui Liu, Yuwen Li, Chuanlong Zhu

“…The gut microbiome and metabolome data were integrated using Data Integration Analysis for Biomarker discovery using Latent cOmponents (DIABLO), which helped identify key microbial and metabolic features associated with CHF. …”
Get full text

LEGAL REGULATION OF THE INTERACTION OF EDUCATIONAL AND MIGRATION POLICIES IN RUSSIA: EQUALITY OF OPPORTUNITIES AND INTEGRATION THROUGH EDUCATION by REZAKOV MAXIM

Get full text

Establishing the best step-up treatments for children with uncontrolled asthma despite inhaled corticosteroids: the EINSTEIN systematic review, network meta-analysis and cost-effec... by Sofia Cividini, Ian Sinha, Giovanna Culeddu, Sarah Donegan, Michelle Maden, Katie Rose, Olivia Fulton, Dyfrig Hughes, Stephen Turner, Catrin Tudur Smith

“…We asked all researchers to share the data they had originally collected with us and combined results using a network meta-analysis. …”
Get full text

Analysis of variant interactions in families with autism points to genes involved in the development of the central nervous system. by Jacek Kaczyński, Marta Pasenkiewicz-Gierula

“…Whole-genome sequencing data of simplex families with autism spectrum disorder (ASD) were analyzed by searching for statistical interactions between loci. …”
Get full text

STUDI POLA INTERAKSI PERILAKU JANGKRIK (Gryllus bimaculatus ) JANTAN DAN BETINA by Anwari Adi Nugroho, Namira Hanin Sal Sabilla, Dwi Setyaningrum, Fikih Putri Prastin, Talila Rima Dani

“…Retrieval of data using direct observation, recording sounds and then recorded in the observation sheet, observation notes, and documentation tools. …”
Get full text

3D scanning probe nanotomography of tissue spheroid fibroblasts interacting with electrospun polyurethane scaffold by A. E. Efimov, O. I. Agapova, L. A. Safonova, M. M. Bobrova, V. A. Parfenov, E. V. Koudan, F. D. A. S. Pereira, E. A. Bulanova, V. A. Mironov, I. I. Agapov

“…Three-dimensional analysis of fibroblasts interacting with electrospun polyurethane fibers was conducted using scanning probe nanotomography with an experimental setup combining ultramicrotome and a scanning probe microscope. …”
Get full text

Prediction of drug-drug interactions in clozapine combination therapy based on physiologically based pharmacokinetic model by MOU Fan, HUANG Zhiwei, CHENG Yu, ZHAO Xue, LI Huafang, YU Shunying

“…The models′ accuracy was evaluated by comparing predicted values of the area under the curve (AUC) and peak concentration (Cmax) to observed data, using the mean percentage error (MPE) and mean absolute percentage error (MAPE) as evaluation indicators. …”
Get full text