The interactions of Lipoprotein(a) with common cardiovascular risk factors in cardiovascular disease risk: evidence based on the UK Biobank by Linjun Ao, Raymond Noordam, J Wouter Jukema, Diana van Heemst, Ko Willems van Dijk

“…Multivariable-adjusted Cox proportional hazards interaction models were used to study whether the associations of Lp(a) with outcomes varied based on the level of total cholesterol (Total-C), low-density lipoprotein-cholesterol (LDL-C), triglycerides (TG) and other cardiovascular risk factors. …”
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Cognitive task analysis of clinicians’ drug–drug interaction management during patient care and implications for alert design by Nervana Elkhadragy, Amanda P Ifeachor, Julie B Diiulio, Karen J Arthur, Michael Weiner, Laura G Militello, Peter A Glassman, Alan J Zillich, Alissa L Russ-Jara

“…Background Drug–drug interactions (DDIs) are common and can result in patient harm. …”
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Coexistence of Sympatric Large Carnivores: Spatio‐Temporal Interactions Between Tigers and Leopards in Parsa National Park, Nepal by Dol Raj Thanet, Pramod Raj Regmi, Babu Ram Lamichhane, Dipanjan Naha, Caitlin Kupferman, James C. Beasley, Mandip Pangeni, Anil Shrestha, Saneer Lamichhane, Haribhadra Acharya, Bed Kumar Dhakal, Bhagawan Raj Dahal, Chiranjibi Prasad Pokheral, Naresh Subedi

“…Camera trap data obtained from 157 sampling sites (2 × 2 km grid cells) were used to assess daily temporal activity patterns, single‐species occupancy, and density of tigers and leopards using spatially explicit capture‐recapture models (SECR) to further examine their coexistence mechanism in light of the recent recovery of tiger populations in PNP. …”
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Genotype-by-environment interaction across THI classes impacts the selection for body weight at young ages in meat quails by Arícia Chaves Zanetti Reis, Daniele Botelho Diniz Marques, Delvan Alves da Silva, Alessandra Alves da Silva, Eula Regina Carrara, Leila de Genova Gaya, Paulo Sávio Lopes, Luiz F. Brito, Renata Veroneze

“…BW data from ten generations, recorded on 7 (BW7), 14 (BW14), 21 (BW21), 28 (BW28), 35 (BW35), and 42 (BW42) days after hatching were used for the analyses. …”
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Involvement of RBP-J interacting and tubulin-associated protein in the distribution of protein regulator of cytokinesis 1 in mitotic spindles by Julia Caspers, Andreas Ritter, Badi Bahrami, Samira Catharina Hoock, Susanne Roth, Alexandra Friemel, Franz Oswald, Frank Louwen, Nina-Naomi Kreis, Juping Yuan

“…The protein regulator of cytokinesis 1 (PRC1) is a key regulator of microtubule crosslinking and bundling, which is crucial for spindle formation and cytokinesis. RITA, the RBP-J interacting and tubulin-associated protein, is a microtubule associated protein. …”
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Irrigation Suitability and Interaction Between Surface Water and Groundwater Influenced by Agriculture Activities in an Arid Plain of Central Asia by Chenwei Tu, Wanrui Wang, Weihua Wang, Farong Huang, Minmin Gao, Yanchun Liu, Peiyao Gong, Yuan Yao

“…This study evaluates the irrigation water quality and groundwater–surface water interaction influenced by agricultural activities in a typical arid plain region using hydrochemical and stable isotopic data from 51 water samples. …”
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Treatment of Onychomycosis and the Drug–Drug Interactions in Patients with Diabetes Mellitus and Diabetic Foot Syndrome: A Systematic Review by David Navarro-Pérez, Aroa Tardáguila-García, Sara García-Oreja, Francisco Javier Álvaro-Afonso, Mateo López-Moral, José Luis Lázaro-Martínez

“…<b>Background:</b> This systematic review reports on treatments for onychomycosis in patients with diabetes and the drug interactions with other drugs in regard to the complicated diabetic patient profile. …”
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Enhanced sign evaluation with AI: A visual data-driven approach by Yi Lin Wong, Pan Wang

“…However, a shortcoming of comprehensibility testing is that it does not provide qualitative information relevant to sign modification and does not facilitate interactions between designers and users. This article advocates the use of visual data to evaluate signs by examining the similarities between signs and drawings produced by end users based on a sign referent given to them. …”
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Phages-bacteria interactions underlying the dynamics of polyhydroxyalkanoate-producing mixed microbial cultures via meta-omics study by Jian Yao, Yan Zeng, Xia Hong, Meng Wang, Quan Zhang, Yating Chen, Min Gou, Zi-Yuan Xia, Yue-Qin Tang

“…A total of 963 metagenome-assembled genomes (MAGs) and 4,294 phage operational taxonomic units (pOTUs) were assembled from bulk metagenomic data. The dynamic changes in the structure of phage and bacterial communities were remarkably consistent. …”
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Resting-state functional magnetic resonance imaging and tryptophan hydroxylase-2 methylation interaction in major depressive disorder by Zhi Xu, Tingting Tan, Yan Jiang, Haiping Tang, Bingwei Chen, Wenji Chen, Yonggui Yuan

“…Methods: Data from 98 patients with MDD and 63 controls were utilized. …”
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Prevalence and factors associated with potential clinically significant drug-drug interactions in patients with cardiovascular diseases at hospital admission by Marović Iva, Udovičić Mario, Rudan Diana, Manola Šime, Samardžić Ivana, Vrca Vesna Bačić, Hadžiabdić Maja Ortner, Marinović Ivana

“…The research was approved by the Hospital’s Ethics Committee and each patient involved in the study signed an informed consent. Lexicomp® Lexi-InteractTM Online (Lexi-Comp, Inc., USA) was used for DDI analysis. …”
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Enhancing the Prediction of Dam Deformations: A Novel Data-Driven Approach by Jonas Ziemer, Gideon Stein, Carolin Wicker, Jannik Jänichen, Daniel Klöpper, Katja Last, Joachim Denzler, Christiane Schmullius, Maha Shadaydeh, Clémence Dubois

“…The analysis provided evidence for the following insights: First, the accuracy of current modeling approaches can be greatly improved by utilizing advanced feature engineering and data-driven model selection. The prediction performance of the pendulum data was improved by utilizing data-driven algorithms, reducing the mean absolute error from 0.51 mm in the baseline model (<i>R</i>² = 0.92) to as low as 0.05 mm using the full model search space (<i>R</i>² = 0.99). …”
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Maternal seafood intake, dietary contaminant exposure, and risk of juvenile idiopathic arthritis: exploring gene-environment interactions by Vilde Øverlien Dåstøl, Vilde Øverlien Dåstøl, Kristine Løkås Haftorn, Hamid Khoshfekr Rudsari, Piotr Pawel Jaholkowski, Piotr Pawel Jaholkowski, Ketil Størdal, Ketil Størdal, Siri Eldevik Håberg, Siri Eldevik Håberg, Clarice R. Weinberg, Lisa G. Rider, Ole A. Andreassen, Ole A. Andreassen, Ole A. Andreassen, Anne Lise Brantsæter, Ida Henriette Caspersen, Ida Henriette Caspersen, Helga Sanner, Helga Sanner

“…A polygenic risk score (PRS) for JIA was used in a subsample to assess gene-environment interactions.ResultsWe identified 217 JIA patients and 71,884 controls. …”
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Human IFN-κ Inhibited Respiratory RNA Virus Replication Dependent on Cell-to-Cell Interaction in the Early Phase by Weihui Fu, Peng Sun, Jun Fan, Longfei Ding, Songhua Yuan, Guanxing Zhai, Miaomiao Zhang, Chenli Qiu, Shuye Zhang, Xiaoyan Zhang, Jianqing Xu, Haijuan Wang

“…Conventional molecular biology methods were used to determine the localization of IFN-κ and its structure and function. …”
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Exploring effector-host interactions in Pyricularia oryzae infections: A molecular and structural approach to rice blast resistance by Zakir Amin, F.A. Mohiddin, Ali Anwar, Asif B. Shikari, Sajad Un Nabi, Tauseef A. Bhat, Vishal Gupta, Fehim Jeelani Wani, Shugufta Parveen, Mohd Salim Mir, Subaya Manzoor, Suhail Ashraf, Mohammad Raish

“…Despite the global importance of rice blast, there is a lack of comprehensive data on the race dynamics of Pyricularia oryzae in temperate ecosystems such as Kashmir, particularly using the newly designated U-i-k-z-ta system, which employs an expanded set of 25 resistance genes and a susceptible check for precise race characterization. …”
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Data-driven mechanisms for network freight platforms: An evolutionary game perspective. by Chan He, Qun Xu, Xu Xu, Feng Kong, Feng Shen

“…The study also highlights important implications for policymakers and industry practitioners, emphasizing the importance of effective data governance and the strategic use of information to shape the future of freight logistics.…”
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Evaluation of drug-drug interaction between Suraxavir Marboxil (GP681) and itraconazole, and assessment of the impact of gene polymorphism by Mai Han, Gang Cui, Yan Zhao, Xianbo Zuo, Xiaoxue Wang, Xin Zhang, Na Mi, Jiangli Jin, Chunyan Xiao, Jing Wang, Wei Wu, Yajuan Li, Jintong Li

“…No significant increase in adverse events was observed during co-administration. Using random forest algorithm, we estimated effects of cytochrome P450 enzymes followed the order of CYP 3A4 &gt; CYP 1A2 &gt; CYP 2C19. …”
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A Diverse, Overlooked Population of Type Ia Supernovae Exhibiting Mid-infrared Signatures of Delayed Circumstellar Interaction by Geoffrey Mo, Kishalay De, Eli Wiston, Nayana A. J., Raffaella Margutti, Danielle Frostig, Jesper Sollerman, Yashvi Sharma, Takashi J. Moriya, Kevin B. Burdge, Jacob Jencson, Viraj R. Karambelkar, Nathan P. Lourie

“…While most known events show evidence for dense nearby CSM identified via peak-light spectroscopy (as SNe Ia-CSM), targeted late-time searches have revealed a handful of cases exhibiting delayed CSM interaction with detached shells. Here we present the first all-sky search for late CSM interaction in SNe Ia using a new image subtraction pipeline for mid-infrared data from the NEOWISE space telescope. …”
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Hybrid epithelial-mesenchymal status of lung cancer dictates metastatic success through differential interaction with NK cells by Ugo Pastorino, Massimo Milione, Paola Orecchia, Massimo Moro, Gabriella Sozzi, Monica Parodi, Giovanni Centonze, Fabio Murianni, Francesca Andriani, Ilaria Roato, Cecilia Gardelli, Melissa Balsamo, Giulia Taiè, Andrea Petretto, Chiara Lavarello ‎, Luca Roz, Massimo Vitale, Giulia Bertolini

“…Interactions with NK cells were investigated in vitro using migration assays, cytotoxic degranulation assays, and evaluation of CD133+ CICs modulation after coculture, and validated in vivo through NK cell neutralization assays. …”
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CWL-PLAS: Task Workflows Assisted by Data Science Cloud Platforms by Andrea Detti, Ludovico Funari, Luca Petrucci, Michele Dorazio, Arianna Mencattini, Eugenio Martinelli

“…The Common Workflow Language (CWL) is a platform-independent description language for the representation of data science workflows consisting of a set of tasks that interact with each other to perform scientific analysis. …”
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