Frog‐Derived Neuroregenerative‐Peptide‐Reinforced Bioactive Hydrogels with Injectability, Thermosensitivity, and Enhanced Neurotrophic Function for Repairing Central Nervous Injuri... by Zhengang Sun, Zhenjuan Sun, Chenxi Du, Hongyu Chen, Xingchao Zhang, Yuanyuan Liu, Fang Dong, Xuexiao Ma, Gang Wei, Haiyuan Yue

“…The clinical treatment of central nervous system (CNS) injuries presents significant challenges due to the inflammatory microenvironment (IME) induced by CNS injury, which inhibits spontaneous neuronal regeneration. …”
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Increased Range of Motion and Function in an Individual with Breast Cancer and Necrotizing Fasciitis—Manual Therapy and Pulsed Short-Wave Diathermy Treatment by Wayne Johnson, David O. Draper

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Controlled release and antibioticeffect of vancomycin-loaded poly(-isopropylacrylamide) nanoparticles as a smart drug delivery system by Liang Lei, Shanlong Li, Xuefeng Kang, Jian Shang

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Collagen mimetic peptides as novel therapeutics for vascular disease in the central nervous system by Olivia L. Bossardet, Joseph M. Holden, Brian J. Del Buono, Eric Schlumpf, Lauren K. Wareham, David J. Calkins

“…Over a 12 weeks period, mice received weekly intravenous treatment of collagen mimetic peptide (CMP) or vehicle (phosphate buffered saline) to assess efficacy in promoting vascular integrity in central brain structures.ResultsFollowing the STZ/HFD regimen, diabetic atherosclerotic ApoE−/− mice treated with CMP exhibited increased vascular integrity compared to vehicle in the cortex and in the CA1 and dentate gyrus regions of the hippocampus, as assed by higher levels of the endothelial cell adhesion glycoprotein CD31 and intravascular collagen IV, increased vascular area, and diminished leakage. …”
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Design and Implementation of a Cyber Physical System for Building Smart Living Spaces by Zhi-yong Bai, Xin-yuan Huang

“…Recently, the integrated control systems with computing, Internet, and the electronic equipment with embedded sensors or identification device, called Cyber Physical Systems (CPSs), have gradually attracted more and more attention in a variety of different areas. …”
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Hybrid Electro‐optical Stimulation Improves Ischemic Brain Damage by Augmenting the Glymphatic System by Min Jae Kim, Jiman Youn, Hong Ju Lee, Seo‐Yeon Lee, Tae‐Gyu Kim, Young‐Jin Jung, Yong‐Il Shin, Byung Tae Choi, Joonsoo Jeong, Hwa Kyoung Shin

“…Herein, a novel hybrid electro‐optical stimulation device is proposed that integrates near‐infrared micro‐light‐emitting diode with transparent microneedles, enabling efficient noninvasive stimulation of the cortical area for ischemic stroke treatment. This study investigates whether this hybrid electro‐optical stimulation enhances the glymphatic system function and ameliorates ischemic brain injury in the middle cerebral artery occlusion and reperfusion (MCAO/R) mice model. …”
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Tocilizumab modulates the activity of the classical and alternative complement pathways in rheumatoid arthritis patients by Iván Ferraz-Amaro, Iván Ferraz-Amaro, Sergio Santos-Concepción, Javier Castro-Hernández, Maria Vanesa Hernández-Hernández, Beatriz Tejera Segura, Cristina Luna, Esmeralda Delgado-Frias, Federico Díaz-González, Federico Díaz-González, Federico Díaz-González

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Thematic analysis of six Asian prehospital emergency medical systems to explore development principles by Amila Ratnayake, Dinesh Bagaria, April B. Llaneta, Ratrawee Pattanarattanamolee, Bui Hai Hoang, Takaaki Suzuki, Kenji Fukushima, Minh Nguyen, Weerasak Phongphuttha, Patrick Joseph G. Tiglao, Niladri Banerjee, Sohan de Silva, Srilal De Silva, Harshit Agarwal, Emelia B. Santamaria, Kriangsak Pintatham, Xuan Quy Le, Shinji Nakahara

“…Background. Well-designed and functioning emergency medical service (EMS) can provide equitable access to emergency care to improve health issues, especially in low- and middle-income countries where the majority of deaths are due to conditions that could be treated with emergency care. …”
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Transcranial electrical stimulation in the treatment of peptic ulcer by Dariya N. Tarasova, Vsevolod V. Skvortsov, Boleslav N. Levitan

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Research progress on biodegradable polymer-based drug delivery systems for the treatment of knee osteoarthritis by Jinchi Zhang, Jinchao Zhang, Hailong Li, Huimin Zhang, Hongyan Meng

“…Currently, clinical aspects are mainly used to treat cartilage degeneration in patients with osteoarthritis of the knee by using different kinds of biodegradable biopolymer materials with excellent physical properties, histocompatibility and other properties, combined with a drug delivery system, which can reduce the level of inflammation and stiffness in the focal area, and maximise the restoration of the patient’s knee joint joint mobility and athletic ability. …”
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Injured Cardiac Tissue-Targeted Delivery of TGFβ1 siRNA by FAP Aptamer-Functionalized Extracellular Vesicles Promotes Cardiac Repair by Kang JY, Mun D, Park M, Yoo G, Kim H, Yun N, Joung B

“…Consequently, hEV@FAP-siTGFβ 1 significantly improved cardiac function, reduced myocardial fibrosis, and decreased cardiomyocyte cross‐sectional area (P < 0.05) without inducing systemic toxicity.Conclusion: hEV@FAP represents a novel approach for targeted delivery of therapeutic siRNA to injured cardiac tissues, providing a promising nanomedicine for cardiac repair. …”
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Therapeutic Effect of High-Definition Transcranial Direct Current Stimulation Combined with Suspension Exercise Training on Lower Limb Motor Function of Stroke Patients by ZHANG Haiquan, HU Chuan, HUANG Lei, LU Wei, WANG Xin

“…ObjectiveTo observe the effect of high-definition transcranial direct current stimulation combined with suspension exercise training on lower limb motor function of stroke patients.MethodsA total of 120 stroke patients treated in the department of rehabilitation medicine of the Shandong Provincial Third Hospital, Shandong University from January 2022 to February 2023 were randomly divided into control group, HD-tDCS group, suspension group and combined treatment group, with 30 cases in each group. …”
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Bibliometric analysis of traditional Chinese medicine in cancer treatment via immune system modulation (2015–2025) by Youfeng Lei, Chunyan Chen

“…The Journal of Ethnopharmacology is the leading journal in this field, publishing a substantial number of highly cited studies. Key research areas include keywords such as “apoptosis,” “expression,” “inflammation,” “extract,” “in vitro,” “activation,” “antioxidant,” and “NF-kappa B,” focusing on exploring the role, mechanisms, and efficacy of TCM in modulating immune responses.ConclusionResearch interest in TCM’s role in treating cancer through immune system regulation continues to grow, underscoring its potential in cancer therapy. …”
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Nanobiomaterials-enabled sensors for heavy metal detection and remediation in wastewater systems: advances in synthesis, characterization, and environmental applications by Lata Deso Abo, Hirpha Adugna Areti, Mani Jayakumar, Magesh Rangaraju, Saminathan Subashini

“…NBMs, which merge the advantages of nanotechnology and biomaterials, exhibit high surface area-to-volume ratios and tailored surface functionalities, making them effective adsorbents for heavy metal ions even at low concentrations. …”
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Efficient delignification of poplar and Chinese fir wood using a peroxyacetic acid/hydrogen peroxide system by Xinde Bao, Meng Yang, Junjie Zhu, Hui Xu, Huiying Dang, Kai Guo, Dingxing Long, Xin Guan, Xiaoyun Chen, Jinguo Lin

“…Additionally, the specific surface area increased by 6.4% in poplar and 30.9% in Chinese fir. …”
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FMT reduces systemic inflammatory response in severe acute pancreatitis by increasing the abundance of intestinal Bifidobacteria and fecal bacteria by Yanning Mao, Yandong Huang, Weiwei Zhang, Huiping Liang, Fengming Liu, Qi Luo, Chunqin Xu, Yi Qin, Jiawen Liu, Shaobo Tang, Huaying Liu, Xiaolong Ge

“…Intestinal microbiota dysbiosis caused by SAP exacerbates systemic inflammatory response syndrome and organ dysfunction. …”
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Comprehensive review on co-integration of conventional systems and advanced oxidation processes for industrial and agricultural wastewater treatment applications by Lata Deso Abo, Mani Jayakumar, Albert Selvakumar Jeyapaul, Magesh Rangaraju, Hirpha Adugna Areti, Ayele Assefa Adugna

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A review of biopolymer innovations in oculoplastic surgery: reconstruction of eyelid, lacrimal, and orbital structures by Merve Kulbay, Kevin Y. Wu, Adam Hocini, Patrick Daigle

“…This review, which spans research from 2015 to 2023, delves into the application and integration of biopolymers and functional biomaterials in these complex areas. The discussion begins by reviewing the key anatomy of the external ocular surface, lacrimal system, and orbit. …”
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Near-infrared light-induced photothermal and immunotherapy system for lung cancer bone metastasis treatment with simultaneous bone repair by Guoqing Zhong, Yali Miao, Jielong Zhou, Yijie He, Wenjie Yang, Chongquan Huang, Yunhui Zhang, Jin Xiao, Bingqing Bai, Jiaqi Zhou, Renshan Li, Tiantian Wei, Yu Zhang, Shi Cheng

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Stearic-Acid-Coated Sand: A Game Changer for Agriculture Water Management by Muhammad Abdullah, Mergen Zhazitov, Nazerke Kydyrbay, Tolagay Duisebayev, Yerbolat Tezekbay, Olzat Toktarbaiuly

“…Structural, chemical, and physical characterizations confirmed the successful functionalization of the sand surface. The coated sand exhibited a high water contact angle (WCA > 150°), indicating strong water repellency and potential for reducing water loss in soil systems. …”
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