Painful Left Bundle Branch Block Syndrome Treated With Conduction System Pacing. A Report of Two Cases by Catalin Pestrea, Constantin Guzgan, Ecaterina Cicala, Radu Vatasescu

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LYMPHATIC SYSTEM: A FORGOTTEN AREA? by G. P. Itkin, M. G. Itkin

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The Experience of Observational Departments’ Functioning for Treatment of Patients with Tuberculosis from COVID-19 Contact and Convalescents after COVID-19 by E. M. Bogorodskaya, E. A. Kotova, E. L. Khristoforova, I. V. Nozdrevatykh

“…During medical care for patients of physiatry profile in Moscow city, a wide range of management decisions consisting in the change of routing system in specialized medical care, was taken. Among them, creation and functioning of observational departments for contact persons from COVID-19 areas and convalescents after COVID-19 play a particular role.Creation of such departments within a large medical institution enabled the contemporary isolation of contact persons from COVID- 19 areas and convalescents after COVID-19 and allowed the additional control of nosocomial infection spread…”
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The application of ultrasound-guided percutaneous transforaminal endoscopy in treating carpal tunnel syndrome by Yun Xu, Shuo Deng, Langhai Xu, Shun Li, Zhongwei Ji

“…Ultrasound was employed to locate the transverse carpal ligament and median nerve, followed by carpal tunnel release using the transforaminal endoscopic system. Hand symptoms and function were assessed at 2 weeks, 1 month, 3 months and 6 months postoperatively using the Boston Carpal Tunnel Questionnaire-Symptom Severity Score (BCTQ-S) and the Boston Carpal Tunnel Questionnaire-Function Status Scale (BCTQ-F). …”
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Potential locations for non-invasive brain stimulation in treating ADHD: Results from a cross-dataset validation of functional connectivity analysis by Yue Yang, Sitong Yuan, Huize Lin, Yi Han, Binlong Zhang, Jinna Yu

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Functional Adaptation in the Brain Habenulo–Mesencephalic Pathway During Cannabinoid Withdrawal by Sonia Aroni, Claudia Sagheddu, Marco Pistis, Anna Lisa Muntoni

“…The mesolimbic reward system originating from dopamine neurons in the ventral tegmental area (VTA) of the midbrain shows a profound reduction in function during cannabinoid withdrawal. …”
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A New Way to Treat Central Nervous System Dysfunction Caused by Musculoskeletal Injuries Using Transcranial Direct Current Stimulation: A Narrative Review by Stéphane Perrey

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Morphological and Functional Changes in Hepatic System Precipitate Liver Disease in Elderly: Addressing Knowledge Gaps and Treatment Challenges by Fatrian Dwicahya, Ulfa Kholili

“…By critically analyzing recent evidence, we identify challenges in treating liver diseases in the elderly and highlight areas requiring further research.…”
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Influence of solid and liquid hydrophobic compounds on characteristics of water located in an adsorption layer of a hydrophilic component of the system by V. V. Turov, V. M. Gun'ko, T. V. Krupska, M. T. Kartel

“…The effects of CDCl3 are much stronger for water in nontreated system than those in compacted composite. This is due to reorganization of water affected both by changes in the confined space effects and the influence of hydrophobic chloroform, which can displace water into small voids (inaccessible for larger chloroform molecules) or larger voids to reduce the contact area of both liquids. …”
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Comprehensive Transcriptomic Analysis of Brain Tissues From the Infarcted Area of MCAO Rats Revealed That Acupuncture Attenuates Brain Injury via the Complement System by Yanlin Liu, Yuting Jin, Yuxin Liu, Jiaqi Gao, Xiaomei Wang, Hongbin Ren, Yabo Hao, Xibin Yang, Kaitao Luo

“…Methods An MCAO rat model was established and treated with acupuncture. Brain tissue from the infarct area was analyzed through RNA sequencing, Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment, and protein–protein interaction (PPI) analyses, followed by qRT‐PCR and western blot validation of key complement‐related genes. …”
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MODERN CONCEPTS OF TREATING HYPERESTHESIS OF HARD TOOTH TISSUES (REVIEW OF LITERATURE) by S.P. Yarova, O.S. Genzytska, Yu.Yu. Yarov, A.A. Komlev

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Programmable production of bioactive extracellular vesicles in vivo to treat myocardial infarction by Siyuan Fu, Zhiyu Wang, Peihong Huang, Guanjun Li, Jian Niu, Zhiyang Li, Guangyue Zu, Pengcheng Zhou, Lianhui Wang, David Tai Leong, Xianguang Ding

“…When surgically implanted, we demonstrate the therapeutic potential of in-situ EV production system to alleviate MI symptoms and improve cardiac function. …”
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Mechanism-based myofilament manipulation to treat diastolic dysfunction in HFpEF by Katherine L. Dominic, Alexandra V. Schmidt, Henk Granzier, Kenneth S. Campbell, Kenneth S. Campbell, Julian E. Stelzer

“…However, there are no therapies that directly treat the primary feature of the disease. This is due in part to the complexity of normal diastolic function, and the challenge of isolating the mechanisms responsible for dysfunction in HFpEF. …”
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When infection threats the mind: an investigation into the cognitive impairment associated with HIV infection by Miguel Braganca

“…The negative impact of infection on neurocognition was confirmed, globally and in all areas evaluated. The main predictors of cognitive functioning were: (1) education, professional status and social class; (2) infection pathway, protective measures and lifestyles; (3) psychotropic drugs and coffee intake; (4) disease stage and nadir CD4 count. …”
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Anticancer effect of surface functionalized nano titanium dioxide with 5‐fluorouracil on oral cancer cell line—An in vitro study by Marco Antonio Rivera Rodriguez, Verónica Campos‐Ibarra, Aruna‐Devi Rasu Chettiar, Latha Marasamy, Ravichandran Manisekaran

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Time to treat the climate and nature crisis as one indivisible global health emergency by Kamran Abbasi, Parveen Ali, Virginia Barbour, Thomas Benfield, Kirsten Bibbins-Domingo, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Robert Mash, Peush Sahni, Wadeia Mohammad Sharief, Paul Yonga, Chris Zielinski

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THE IMPORTANCE OF HIGH-RESOLUTION COMPUTED TOMOGRAPHY IN EVALUATING THE EFFICACY OF RITUXIMAB IN PATIENTS WITH INTERSTITIAL LUNG DISEASE IN SYSTEMIC SCLEROSIS by O. A. Koneva, O. V. Desinova, L. P. Ananyeva, N. V. Kovaleva

“…Multi-slice spiral computed tomography (MSCT) of the chest is the gold standard for confirming interstitial changes in the lung; but the role of this technique in evaluating the efficiency of therapy for systemic sclerosis (SSc) has not been fully defined.Objective: to assess the time course of changes in the lung according to chest MSCT findings and pulmonary function test (PFT) results in SSc patients and interstitial lung disease (ILD) during of active treatment.Subjects and methods. …”
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Digitized Precision Corrective Osteotomy for Treating Knee Joint Deformities: Current Evidence and Future Perspectives by Xiaoyu Wang, Qinglin Kang

“…Digitized orthopedic surgery has favorable potential in terms of surgical practice, skill training, and delivery of healthcare information. Surgical navigation systems with synthetic functions of planning, training, and robotic assistance should be developed.…”
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Astragaloside IV increases PDHA1 in mesenchymal stem cell exosomes to treat myocardial infarction by Sha Zhongxin, Chen Zhijie, Du Feng, Guo Mei Qin, Zhong Ya, Hu Jinxin, Wei Zhang, Yu Zhenqiu

“…The effect of AS-IV in treating AMI via MSC exosomes was evaluated by cardiac ultrasound to assess cardiac function, TTC staining to observe myocardial infarction area, TUNEL staining was used to analyze cell apoptosis, and ELISA to measure the IL-6 and TNF-α in myocardial tissue. …”
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The Alpine Metropolitan-Mountain Faced with Global Challenges. Reflections on the Case of Turin by Giuseppe Dematteis

“…The analysis helps to identify some general characters of the Alpine spaces included in metropolitan territorial systems. The increasing mutual dependences between them stimulates a reflexion on the integration of rural mountain areas in metropolitan regions, starting from new mutual dependences. …”
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