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1201
Modulating Cognition-Linked Histone Acetyltransferases (HATs) as a Therapeutic Strategy for Neurodegenerative Diseases: Recent Advances and Future Trends
Published 2025-06-01“…Recent investigations into the neuroepigenome of the brain are providing unparalleled understanding into the impact of post-translational modifications (PTMs) of histones in regulating dynamic gene expression patterns required for adult brain cognitive function and plasticity. …”
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1202
Older Jehovah’s Witnesses with Acute Myeloid Leukemia: Hypomethylating Agents and Venetoclax as a Transfusion-Sparing Approach
Published 2025-06-01“…This case series reports the outcomes of four older JW patients with AML treated with azacitidine (Aza) and venetoclax (Ven), including two with hyperleukocytosis and FLT3-ITD mutations. …”
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1203
Improving cole crop safety and weed control response with chloroacetamide and oxyfluorfen herbicide combinations
Published 2025-01-01“…In field studies, nontreated plots exhibited significant weed growth, reaching up to 71% coverage 28 d after transplanting (DATr), whereas herbicide-treated plots exhibited weed cover at or below 10% by 28 DATr. …”
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1204
Mechanisms of Decidual Dysfunction and Infertility in Endometriosis: Roles of Prostaglandins and SASP
Published 2025-01-01“…ABSTRACT Background Endometriosis is a challenging disease to treat and one of the leading causes of infertility. …”
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1205
CRISPR/Cas-Based Ex Vivo Gene Therapy and Lysosomal Storage Disorders: A Perspective Beyond Cas9
Published 2025-07-01“…As genetic diseases, LSDs can be treated with gene therapies (GT), including the CRISPR/Cas systems. …”
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1206
General anesthesia of endhotracheal tube in cholesistektomy with cholelithiasis with cholecystitis: A case report
Published 2025-01-01“…With the proper anesthetic modifications, the patient stayed steady throughout the procedure. …”
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1207
Precipitation of Calcium Phosphates in the Presence of Collagen Type I on Four Different Bioactive Titanium Surfaces: an in Vitro Study
Published 2015-12-01“…Material and Methods: Blasted titanium discs were treated with four different surface modifications, alkali and heat, sodium fluoride, anodic oxidation and hydroxyapatite coating. …”
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1208
Outcome Analysis in Epilepsy Patients Undergoing Switchover from Levetiracetam to Brivaracetam
Published 2025-01-01“…The safety profile included tolerability of dose modifications and treatment-emergent adverse events. …”
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1209
Cabazitaxel-induced ureteritis in metastatic castration-resistant prostate cancer patients: a single center case series 2014–2024
Published 2025-04-01“…Case presentation Between June 2014 and May 2024, 354 patients diagnosed with mCRPC were treated with CBZ at the Department of Oncology, Vejle Hospital. …”
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1210
Efficient delignification of poplar and Chinese fir wood using a peroxyacetic acid/hydrogen peroxide system
Published 2025-07-01“…Abstract The efficient removal of lignin is crucial for process optimization, as it enhances the exposure of polar groups in wood and provides interfacial binding sites for subsequent material modifications. In this study, an environmentally friendly peracetic acid/ hydrogen peroxide system was employed to delignify fast-growing wood. …”
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1211
Effect of adding various supplements on physicochemical properties and starch digestibility of cooked rice
Published 2024-10-01“…Abstract This study investigated the physicochemical modifications of cooked rice caused by adding various supplements (rapeseed oil, dried wasabi powder, and dried chili pepper powder). …”
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1212
Retinal-ESRGAN: A Hybrid GAN Model Approach for Retinal Image Super-Resolution Coupled With Reduced Training Time and Computational Resources for Improved Diagnostic Accuracy
Published 2025-01-01“…The model incorporates architectural modifications with respect to generator and discriminator network using Google Colaboratory and TensorFlow 2.0 facilitating limited resource usage. …”
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1213
Network pharmacology-based study in polymetformin’s new function of blocking ages/rage pathway curing diabetic complications
Published 2025-06-01“…The study discovered that PL interacted with AGEs via both non-covalent and covalent modifications, altering AGEs’ binding sites and antagonizing the AGEs-RAGE pathway. …”
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1214
Increased functional potency of multi-edited CAR-T cells manufactured by a non-viral transfection system
Published 2025-03-01“…Chimeric antigen receptor (CAR)-T cell therapy represents a breakthrough for the treatment of hematological malignancies. However, to treat solid tumors and certain hematologic cancers, next-generation CAR-T cells require further genetic modifications to overcome some of the current limitations. …”
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1215
Effects of microwave heating on coal seam property for full-cycle in situ exploitation
Published 2025-10-01“…Systematic investigations quantify microwave-induced structural modifications in coal matrices, characterizing porosity, permeability, fracture networks, and surface morphology evolution under varied parameters. …”
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1216
Diagnostic value of bronchoalveolar lavage in children with nonresponding community-acquired pneumonia
Published 2017-10-01“…For positive aerobic culture results, BAL results guided modifications of antibiotic regimens in 21 episodes (21 of 38, 55.3%). …”
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1217
Homozygous Familial Hypercholesterolemia: Case Series and Review of the Literature
Published 2011-01-01“…Treatment options consist of lifestyle modifications, lipid-lowering medications, LDL aphaeresis, and orthotopic liver transplantation (OLT). …”
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1218
Endoscopy- and Monitored Anesthesia Care-Assisted High-Resolution Impedance Manometry Improves Clinical Management
Published 2018-01-01“…The majority of these patients were treated successfully with targeted interventions, including per oral endoscopic myotomy, gastrostomy, botox injection, medical therapy, and dietary modifications.…”
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1219
Underestimated virus impaired cognition-more evidence and more work to do
Published 2025-05-01“…This review focuses on new findings linking viral infection to NDs and explores how viral modifications of cellular functions can impact the development of neurodegeneration and will also explore the therapeutic potential of antiviral drugs in NDs.…”
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1220
Different approaches for plasma nitrocarburizing of austenitic stainless steel using a plasma-activated solid carbon precursor in a hot-wall reactor
Published 2025-01-01“…In particular, the influence of afterglow and direct glow conditions during short-time nitrocarburizing treatments performed at 440 °C in a N2–H2 plasma on the modifications of the resulting surface properties of AISI 316L austenitic stainless steel is studied comparatively. …”
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