Showing 101 - 120 results of 1,358 for search 'treating modification', query time: 0.11s Refine Results
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    Sodium Butyrate Attenuates Diabetic Kidney Disease Partially via Histone Butyrylation Modification by Tingting Zhou, Huiwen Xu, Xi Cheng, Yanqiu He, Qian Ren, Dongzhe Li, Yumei Xie, Chenlin Gao, Yuanyuan Zhang, Xiaodong Sun, Yong Xu, Wei Huang

    Published 2022-01-01
    “…Histone lysine butyrylation (Kbu), a novel histone modification marker induced by butyrate, has been found to be involved in the regulation of pathophysiological processes. …”
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    Visualization analysis of breast cancer-related ubiquitination modifications over the past two decades by Yongxiang Li, Yiyang Wang, Yubo Jing, Youseng Zhu, Xinzhu Huang, JunYi Wang, Elihamu Dilraba, Chenming Guo

    Published 2025-03-01
    “…Abstract Background Ubiquitination is a type of post-translational modification, referring to the process in which the small molecular protein ubiquitin covalently binds to target proteins under the catalysis of a series of enzymes. …”
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  7. 107

    Methionine-driven methylation modification overcomes plasmid-mediated high-level tigecycline resistance by Dan Fang, Tianqi Xu, Fulei Li, Yue Sun, Jingyi Sun, Yanqing Yin, Haijie Zhang, Zhiqiang Wang, Yuan Liu

    Published 2025-01-01
    “…Abstract Tigecycline is a last-resort antibiotic to treat complicated infections caused by multidrug-resistant pathogens, while the emergence of plasmid-mediated tet(X) family severely compromises its clinical efficacy. …”
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  8. 108

    Effect of Tilted Nanostructures on Anisotropic Wetting Behavior on PET Surfaces by Oxygen Plasma Modification by WANG Yitian, LI Yupeng, HUO Lei, LEI Mingkai

    Published 2024-12-01
    “…In order to improve the wettability of polymer surfaces, oxygen plasma modification technology was used to treat the surface of polyethylene terephthalate (PET) under the condition of 200 W for 90 min using sample holders with inclination angles of 30°, 45° and 60°.The nanostructures with tilt angles and lengths of 32.5° and 2.36 μm,45.2° and 2.15 μm,59.5° and 2.00 μm were prepared, respectively.Anisotropic wetting of liquid droplets and directional flow behavior of liquid were studied on the PET surfaces after modified by plasma.Additionally,the direction opposite to the tilted nanostructure was referred to as the Y+direction, the direction along the tilted nanostructure was referred to as the Y- direction, and the direction perpendicular to Y± was referred to as the X± direction.Results showed that the contact angle of the droplet on the PET surfaces modified by plasma decreased, and the wetting length increased with the increase of inclination angle of the sample holders.Meanwhile, the static contact angle of the droplet in the X± direction was greater than that in the Y± direction,and the wetting length in the X± direction was smaller than that in the Y± direction.Continuous water injection was carried out on the PET surfaces modified by plasma.The droplets were pinned in the Y- direction and flowed in the Y+direction.Furthermore, the average flow velocities of droplets on the plasmamodified surface at 30°,45° and 60° inclination angles were 0.017 0,0.021 0 and 0.022 7 mm/s,respectively.Among them,the droplets on the PET surfaces after modified by plasma at 60° inclination angle had a flow velocity of 2.39 times that of the original surfaces in the Y+direction.…”
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    The Effect of Organic Acid Modification on the Pore Structure and Fractal Features of 1/3 Coking Coal by Jiafeng Fan, Feng Cai

    Published 2025-04-01
    “…The acidification modification of coal seams is a significant technical measure for transforming coalbed methane reservoirs and enhancing the permeability of coal seams, thereby improving the extractability of coalbed methane. …”
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    A study on the impact of electrode and membrane modification in stacked microbial fuel cells for wastewater treatment by Aritro Banerjee, Rajnish Kaur Calay, Somil Thakur, Mohamad Y. Mustafa

    Published 2025-01-01
    “…This study investigates the efficacy of treating wastewater using microbial fuel cell (MFC) technology to the safe limits for discharge in the environment. …”
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    Helicobacter pylori employs a general protein glycosylation system for the modification of outer membrane adhesins by Kai-Wen Teng, Kai-Siang Hsieh, Ji-Shiuan Hung, Chun-Jen Wang, En-Chi Liao, Pei-Chun Chen, Ying-Hsuan Lin, Deng-Chyang Wu, Chun-Hung Lin, Wen-Ching Wang, Hong-Lin Chan, Shau-Ku Huang, Mou-Chieh Kao

    Published 2022-12-01
    “…The current findings reveal that H. pylori employs a general protein glycosylation system related to LPS biosynthesis for adhesin modification and its biological significance. The enzymes required for adhesin glycosylation rather than the adhesins themselves are potentially better drug targets for preventing or treating H. pylori infection.…”
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    Targeting epigenetic and post-translational modifications of NRF2: key regulatory factors in disease treatment by Xinyi Yang, Yingchao Liu, Jinghao Cao, Cuiyun Wu, Lusheng Tang, Wenxia Bian, Yuhan Chen, Lingyan Yu, Yunyi Wu, Sainan Li, Yuhuan Shen, Jun Xia, Jing Du

    Published 2025-04-01
    “…Targeting NRF2 offers potential therapeutic avenues for treating various diseases. NRF2 is regulated through two principal mechanisms: post-translational modifications (PTMs) and epigenetic alterations. …”
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