Pluchea dioscoridis extract: A novel therapeutic approach for polycystic ovary syndrome targeting ovarian morphology, dopamine pathways, and neurobehavior in relation to its phytoc... by Rasha Atta, Sahar Galal Gouda, Marwa Hussein Mohamed, Sherif M Afifi, Mahmoud I Nassar, Mohamed A Farag, Abdelsamed I Elshamy, Mohamed A Zayed, Thamer Alqurashi, Shimaa Mohammad Yousof

“…Histological analysis revealed less cystic follicles and a reinstated normal ovarian architecture in rats treated with P. dioscoridis compared to PCOS group (P < 0.05%). …”
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Nanoparticles assisted drug delivery for effective management of Glioblastoma by Mansi Damani, Nagesh Nilawar, Munira Momin, Raghumani Singh Ningthoujham, Tabassum Khan

“…Specifically, the blood-brain barrier (BBB) and the blood-brain tumor barrier (BBTB) impede the effective concentration of therapeutic agents within the brain, posing a significant challenge in treating GBM. The primary focus of current research has pivoted towards nanotechnology to address these limitations. …”
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Exploration of TCM Comprehensive Treatment of Irritable Bowel Syndrome Based on Pathophysiological Mechanism by Xu X, Huang Y, Ma Z, Liu Z

“…This study aimed to investigate the efficacy and safety of Traditional Chinese Medicine (TCM) in treating IBS, focusing on the pathophysiological mechanisms underlying the disorder, to provide insights into a promising complementary approach for managing IBS, with potential applications in clinical practice to improve symptom management and patient quality of life. …”
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471 Defining proteomic and cellular elements of the pancreatic ductal adenocarcinoma (PDAC) tumor microenvironment with mass spectrometry imaging by Caroline Kittrell, Blake Sells, Lyndsay Young, Peggi Angel, Richard Drake

“…Objectives/Goals: Currently, a lack of screening markers and targeted therapies prevent clinicians from successfully treating PDAC. Precision medicine may allow oncologists to better combat this disease. …”
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The Reconsolidation of Traumatic Memories Protocol’s adjustments to the remote treatment of injured Ukrainian military personnel in hospital settings by Viktoriia Gorbunova, Robin Hampton

“…The main adjustments involved on-site adaptations (using the procedure room, utilising nurse assistance, ensuring a stable Internet connection) and modifications to the procedure (conducting shorter sessions, up to 45 min), delegating some Protocol administration steps to patients, and using military jargon and commands.Conclusions: The online administration of the RTM Protocol shows promise for treating combat-related ASD in hospital settings, providing a structured intervention for recovering military personnel, and ensuring accessibility and effectiveness in resource-limited settings.…”
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Effect of histone demethylase KDM5B on long-term cognitive impairment in neonatal rats induced by sevoflurane by Yanhong Wang, Yanhong Wang, Yun Chen, Mengxiao Zhang, Chengdong Yuan, Yu Zhang, Xingjian Liu, Yi Zhang, Xiaoli Liang

“…From postnatal day 22 to 36, rats in the +AS8351 group were treated with AS8351 while those in the Sevoflurane group and control group were treated with normal saline. …”
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Assessment of dental, skeletal, and soft tissue changes following mandibular advancement with Invisalign in skeletal Class II by Hassan Al Subaie, Ghassan Alturki, Fahad Alsulaimani, Salma Ghoneim, Hosam Baeshen

“…Objective: This study evaluated the dentoskeletal and soft tissue changes for Class II malocclusion patients treated with Invisalign clear aligners with mandibular wings (IAMW). …”
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Potential of diterpenoid andrographolide in COVID-19 therapy: an insight on its antiviral-, immunomodulatory-, anti-inflammatory-, antioxidant- and antithrombotic- properties by Biswanath Dinda, Manikarna Dinda, Subhajit Dinda, Bishu Karmakar

“…Moreover, Andro prevents sepsis-related complications in influenza virus-infected or LPS-treated mice, by suppression of inflammation, accumulation of macrophages and neutrophils and oxidative stress in lung tissues through deactivation of NF-κB (via covalent modification of Cys62 of p50) and JAK/STAT and activation of Nrf2/HO-1 pathways. …”
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Early effects of PCSK9 inhibitors: evolocumab versus alirocumab by Su-Hyun Bae, Bong-Joon Kim, Soo-Jin Kim, Sung-Il Im, Hyun-Su Kim, Jung-Ho Heo

“…Background The significance of risk modification in patients with acute coronary syndrome (ACS) is well recognized; however, the optimal timing for adminstering PCSK9 inhibitors remains unclear. …”
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Spontaneous Growth Induced by a Biologically Oriented V Class Restoration (BOVR) Technique: A 3D Prospective Study by Davide Farronato, Giuseppe Messina, Luciano Laveglia, Pietro Mario Pasini, Lorenzo Azzi, Marco Farronato

“…<b>Background:</b> The behavior of soft tissues following recession type 1 (RT1) and/or non-carious cervical lesions (NCCLs) treated with class V restorations is not well understood. …”
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Influence of acidified-biochar on phosphorus and potassium availability in alkaline sandy soil by Tamer A. Elbana, Noura Bakr, Sahar A. Shahin, Nahed A. A. Azab, Soad M. El-Ashry

“…A 15-week incubation was conducted using sandy alkaline soil pre-treated with 0.48 Mg ha-1 of superphosphate fertilizer. …”
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Oxygen plasma treatment to mitigate the shedding of fragmented fibres (microplastics) from polyester textiles by Abdul Jabbar, Michael Bryant, Josh Armitage, Muhammad Tausif

“…The impact of textile material and structural variables as well as chemical modification of textiles to mitigate the release of FFs has previously been reported. …”
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The use of combined fenestrated and bifurcated endografts in fenestrated aortic repair by Eric Dorenberg, Anne-Marte Schrøder-Aasen, Beate Lindberg, Rune Andersen, Steinar Guvåg, Ulrik Carling

“…Results Twelve patients were treated with a modular endograft (group A) and 13 patients with a combined endograft design (group B). …”
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PSAT1 is upregulated by METTL3 to attenuate high glucose-induced retinal pigment epithelial cell apoptosis and oxidative stress by Xiaofeng Du, Yanting Wang, Fan Gao

“…Methods High-glucose (HG) was used to treat human retinal pigment epithelial cells (ARPE-19) to construct a cell injury model. …”
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The Effects of Combined Micron-Scale Surface and Different Nanoscale Features on Cell Response by Yi Kang, Xuelei Ren, Xin Yuan, Li Ma, Youneng Xie, Zeyu Bian, Jun Zuo, Xiyang Wang, Zhiming Yu, Kechao Zhou, Qiuping Wei

“…Sandblasting and acid-etching (SLA) and anodization are the two most commonly used methods for surface modification of biomedical titanium. However, there are unavoidable problems such as residual sand particles and lack of hydrophilicity on the surface of titanium sheets treated with SLA technology. …”
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Scriptaid Improves Cashmere Goat Embryo Reprogramming by Affecting Donor Cell Pluripotency Molecule NANOG Expression by Xiaoshu Zhe, Hairui Ma, Wenqi Zhang, Rui Ding, Fei Hao, Yuan Gao, Gumara Uri, Gellegen Jiri, Garangtu Jiri, Dongjun Liu

“…In this study, we used Albas cashmere goat cells as donor cells, treated them with Scriptaid, and constructed embryos using SCNT. …”
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Inhibition of O‐GlcNAcylation protects from Shiga toxin‐mediated cell injury and lethality in host by Kyung‐Soo Lee, Jieun Lee, Pureum Lee, Bong Chan Jeon, Min Yeong Song, Sojung Kwak, Jungwoon Lee, Jun‐Seob Kim, Doo‐Jin Kim, Ji Hyung Kim, Vernon L Tesh, Moo‐Seung Lee, Sung‐Kyun Park

“…Here, we report that O‐GlcNAcylation, a type of post‐translational modification, was acutely increased upon induction of endoplasmic reticulum (ER) stress in host cells by Stxs. …”
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Acquired Bacterial Resistance to Antibiotics and Resistance Genes: From Past to Future by Michela Galgano, Francesco Pellegrini, Elisabetta Catalano, Loredana Capozzi, Laura Del Sambro, Alessio Sposato, Maria Stella Lucente, Violetta Iris Vasinioti, Cristiana Catella, Amienwanlen Eugene Odigie, Maria Tempesta, Annamaria Pratelli, Paolo Capozza

“…The discovery, commercialization, and regular administration of antimicrobial agents have revolutionized the therapeutic paradigm, making it possible to treat previously untreatable and fatal infections. …”
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Eosinophilic Colitis: University of Minnesota Experience and Literature Review by Wolfgang B. Gaertner, Jennifer E. MacDonald, Mary R. Kwaan, Christopher Shepela, Robert Madoff, Jose Jessurun, Genevieve B. Melton

“…The pediatric patients responded very well to dietary modifications, with no recurrences. The adult patients were treated with steroids and did not respond. …”
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Stem cells in the treatment of myocardial injury-induced cardiomyopathy: mechanisms and efficient utilization strategies by Jiali Yang, Jiali Yang, Tian Yue, Jian He, Jian He, Shiqiang Xiong, Yan Luo, Jun Hou

“…Pretreatment of stem cells or genetic modification to enhance the adaptability of stem cells to the environment, or the use of new biomaterials to assist stem cells transplantation is an effective optimization scheme and significantly enhances the therapeutic effect of stem cells therapy for cardiomyopathy. …”
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