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741
Computational Study of Trisindoline 5 Against Overexpressed EGFR Protein on Breast Cancer Stem Cell
Published 2025-01-01“…The existing inhibitory drugs used to treat the EGFR that act as the master regulator of the signaling network still have a limited response in breast cancer. …”
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742
Lignocellulose−based insulation materials: A review of sustainable and biodegradable solutions for energy efficiency
Published 2024-11-01“…Moreover, with interest centered on the integration of lignocellulosic waste into the modification of biodegradable polymers to produce thermal insulation materials, prospects are promising for utilizing treated lignocellulose, cellulose, and their derivatives (such as nanocellulose and microcrystalline cellulose) as economical materials for developing biodegradable insulators. …”
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743
Study on the Synthesis and Performance of Bio-Based Waterproof and Antifouling Finishing Agents for Fabrics
Published 2025-04-01“…To broaden the application of bio-based antifouling self-cleaning finishing agents on cotton fabric surfaces, a waterborne polyurethane emulsion (GWPU) with excellent hydrophobic and antifouling properties was prepared and applied to cotton fabric surface treatment.GWPU was synthesized using glycerol monooleate (GMO) as a chain extender and hydroxyethyl acrylate (HEA) as an end-capping agent,followed by UV curing treatment to prepare GWPU films and cotton fabrics.Subsequently, the chemical structure, functional groups, and surface morphology of the samples were analyzed by FT-IR spectroscopy and scanning electron microscopy.Results showed that GMO was successfully incorporated into waterborne polyurethane (WPU).GWPU formed a continuous film-like structure on the cotton fiber surface, significantly enhancing the fabric’s hydrophobic and antifouling properties.The contact angle of liquid pollutants on the UV-cured GWPU-treated cotton fabric exceeded 110°.Moreover, increasing the GMO content led to larger emulsion particle sizes, and GWPU exhibited superior thermal properties compared to WPU.When the mass fraction of GMO reached 0.5%, the GWPU film achieved optimal tensile strength and elongation at break.Overall, this study successfully prepared GWPU emulsion and realized its effective application on cotton fabric surfaces,significantly improving the fabric’s functionality.GWPU demonstrated excellent physical properties and thermal stability, offering a novel approach for the functional modification of textile materials and showing promising application prospects.…”
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744
Clean air technologies: Modern approaches to reducing the toxicity of wood slab materials
Published 2024-01-01“…The introduction of acid-treated vegetable fillers into the CFS in the amount of 2-3 wt. h. per 100 wt. h. of resin allowed to reduce the content of free formaldehyde in liquid glue by 6-12 times. …”
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745
Polymethylmethacrylate augmentation of conventional pedicle screws in spine surgery – A modified classical method
Published 2025-04-01“…Results: A total of 47 patients were treated with 700 conventional screws. A total of 26/700 screws (3.71%) showed CL. …”
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746
Usefulness of methotrexate in the treatment of rheumatoid arthritis
Published 2024-11-01“…Conclusions: Treatment modification aimed at reducing adverse effects improves patient comfort without affecting treatment efficacy. …”
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747
Evaluation of the eco-friendly contribution of cashew leaf ash in sustainable lateritic soil road pavement construction
Published 2025-06-01“…It is recommended to use lateritic soil treated with 6 % CLA and compacted at 28 days curing age for sub-base in flexible pavement construction. …”
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748
CENTRALISED SURVEY ON THE UNDERTREATMENT OF THE HYPERCHOLESTEROLEMIA IN RUSSIA (CEPHEUS)
Published 2013-08-01“…The study participants received lipid-lowering therapy for at least 3 months (no dose modification for ≥6 weeks). The start-date and end-date of the study were Oct 22nd 2010 and Mar 22nd 2011, respectively. …”
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749
Optimization of Compressive Strength Properties in Fused Deposition Modeling 3D Printed PLA/HA Composites for Bone Tissue Engineering Applications
Published 2025-05-01“…ABSTRACT This study investigates the optimization of 3D‐printed polylactic acid (PLA) and hydroxyapatite (HA) composites for biomedical applications, focusing on enhancing mechanical properties through process parameter optimization and surface modification. The response surface methodology (RSM), along with post hoc statistical validation using Tukey's HSD test, was employed to evaluate the influence of nozzle temperature (200°C–240°C), layer height (0.1–0.3 mm), and HA filler ratio (3–9 wt%) on the compressive strength of both untreated and chemically treated composites. …”
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750
Small-molecule inhibitors of 6-phosphofructo-1-kinase simultaneously suppress lactate and superoxide generation in cancer cells.
Published 2025-01-01“…Deregulated energy metabolism is a hallmark of cancer, characterized by increased glycolytic flux. Cancer-specific modification of 6-phosphofructo-1-kinase (PFK) impairs its ability to regulate the enzyme's activity which increases glycolytic flux. …”
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751
The impact of the early tenotomy of Achilles tendon on the length and results of congenital clubfoot severe forms treatment
Published 2019-01-01“…In this paper we present our modification of the Ponseti method which we have been using for the treatment of severe forms of congenital clubfoot since 2007. …”
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752
Optimizing the thermal treatment procedure using electrochemical methods to improve the performance of vanadium redox flow batteries
Published 2025-06-01“…An interesting conclusion is that thermal treatment with an optimized procedure can sufficiently catalyze vanadium redox reactions on graphite felts better than those treated with electro-catalysts impressing no need for further electrode modification.…”
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753
Dehydrocostus lactone: a comprehensive review on its isolation, chemical transformations, and pharmacological potential
Published 2025-05-01“…It also exhibits promise in treating benign prostatic hyperplasia, bone remodeling disorders, and endometriosis. …”
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754
Practices employed by audiologists in the management of adult patients with multidrug-resistant tuberculosis in South Africa
Published 2015-11-01“…Introduction: Aminoglycosides used for treating multidrug-resistant (MDR) tuberculosis are ototoxic, leading to a need for audiological monitoring. …”
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755
Gut Microbiome as a Target of Intervention in Inflammatory Bowel Disease Pathogenesis and Therapy
Published 2024-10-01“…Finally, we will highlight microbiome-based therapy as a novel and promising strategy to treat and manage IBD.…”
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756
The Effect of Sleep Disruption on Cardiometabolic Health
Published 2025-01-01“…The latest evidence points to the role of sleep-induced changes in the composition and function of gut microbiota, which may contribute to metabolic dysfunction through modifications in the intestinal barrier and inflammatory responses. …”
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757
Effect of laser shock peening on microstructure and wear resistance for 15-5 PH stainless steel
Published 2025-05-01“…Laser shock peening (LSP) is an advanced surface modification technology that can improve the mechanical properties of metallic parts effectively. …”
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758
Catalytic para-xylene maximization. Part X: Toluene disproportionation on HF promoted H-ZSM-5 catalysts
Published 2012-12-01“…This doping caused pore size modification of the H-ZSM-5 catalyst. The reaction was carried out in a fixed bed flow type reactor. …”
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759
Management of Chronic Granular Hypertrophic Pharyngitis (Vrunda) through Ayurveda: A Paediatric Case Report
Published 2025-06-01“…This case study aims to demonstrate the effectiveness and importance of Ayurvedic treatment principles in treating chronic granular hypertrophic pharyngitis, or Vrunda, in a paediatric patient.…”
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760
Impact of Heat Treatment on Microstructure Evolution in Grey Cast Iron EN-GJL-300
Published 2025-05-01“…Continuous cooling with three different rates and two other non-continuous treatments (austempering and ausforming) were used to treat the experimental samples. The research was focused on modification of the matrix microstructure, initially pearlitic. …”
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