Are bisphosphonates effective in the treatment of osteoarthritis pain? A meta-analysis and systematic review. by Alison J Davis, Toby O Smith, Caroline B Hing, Nidhi Sofat

“…Limitations of the studies we analysed included the differences in duration of bisphosphonate use, the dose and route of administration and the lack of long-term data on OA joint structure modification post-bisphosphonate therapy. Future more targeted studies are required to appreciate the value of bisphosphonates in treating osteoarthritis pain.…”
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HADHA-mediated regulation of JAK/STAT3 signaling in glioblastoma: a metabolic-epigenetic axis by Kan Wang, Yifei Xiao, Jinxin Wan, Yuanqi Chu, Ruipeng Zheng, Fengjun Lv, Guang Yang, Mingchun Yang, Haitao Ge, Yuwen Song, Yu Cheng

“…By targeting the metabolic-epigenetic pathway, this strategy presents a promising approach for treating this devastating disorder.…”
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The Value of a Modified Posterior Thigh Flap with Z-Plasty for Reconstruction of Ischial Tuberosity Pressure Ulcers: A Retrospective Single Center Analysis by Maximilian C. Stumpfe, Raymund E. Horch, Wibke Müller-Seubert

“…In this retrospective study, six patients with seven ischial pressure ulcers were treated between 2003 and 2024 using this approach. …”
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Transforming waste into stability: improving the soft clay soil with polyethylene terephthalate (PET) column as a sustainable solution by Ng Jun Shen, Muzamir Hasan

“…The previous studies only investigated the modification of stone columns through different sustainable materials, like ash materials. …”
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Evaluating the Effectiveness of Low-Silica X and Copper-Modified Low-Silica X Zeolite Adsorbents for Cyanide Ions Removal From Aqueous Solutions by Leta Dereje Wilessa, Abdi Nemera Emana, Abdisa Jabesa, Workisa Bacha Garuma, Mani Jayakumar

“…Environmental issues about treating wastewater that contains cyanide with adsorption technology have grown, necessitating the development of a reliable yet easy technique. …”
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In vitro and in vivo antifungal activity of Minocycline albumin nanoparticles in combination with fluconazole against azole-resistant Candida spp by Lulu An, Xiaowen Huang, Meizhen Zhong, Jiaan Wu, Mei Liu, Liqian Geng, Yongyong Li, Xiuli Wang, Lianjuan Yang, Jingwen Tan

“…Abstract Despite the widespread use of fluconazole (FLC) in treating Candida infections, the emergence of drug resistance has become an increasing concern. …”
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Palmitoylation prevents B7-H4 lysosomal degradation sustaining tumor immune evasion by Yijian Yan, Jiali Yu, Weichao Wang, Ying Xu, Kole Tison, Rongxin Xiao, Sara Grove, Shuang Wei, Linda Vatan, Max Wicha, Ilona Kryczek, Weiping Zou

“…However, the post-translational modification (PTM) of B7-H4 and its translational potential in cancer remains incompletely understood. …”
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Rational approach to nutrition for patients with gout by M. A. Gromova, V. V. Tsurko, A. S. Melekhina

“…Gout is a complex multifactorial disease associated with the deposition of crystals of sodium monourate in various tissues of the body and the emergence, in this regard, of chronic hyperuricemia, which is clinically manifested by acute recurrent arthritis and the formation of gouty nodes – tofus. Methods of treating gout can be divided into two groups: lifestyle modification / change in eating habits and pharmacotherapy. …”
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SuoquanYishen formula improves renal cellular senescence by inhibiting YTHDF1-Rubicon axis to promote autophagy in diabetic kidney disease by Zijie Yan, Lin Zhang, Tianpeng Ma, Yong Yuan, Yu Kang, Shuman Liu, BoCen Chen, Kai Li, Man Xiao, Man Xiao, Yiqiang Xie, Yiqiang Xie

“…SuoquanYishen formula (SQYSF), a traditional Chinese herbal prescription for treating diabetic kidney disease (DKD), has demonstrated clinical efficacy in lowering blood glucose and alleviating renal damage. …”
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Interaction of the anion [2-B₁₀H₉O(CH₂)₄O]− with secondary amines by E. Yu. Matveev, S. S. Novikov, V. Ya. Levitskaya, A. I. Nichugovskiy, I. E. Sokolov, K. Yu. Zhizhin, N. T. Kuznetsov

“…One of the most promising methods of treating malignant tumors is 10B-neutron capture therapy. …”
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Treatment of mine water containing ammonia nitrogen by sodium hexametaphosphate modified zeolite by Liping ZHANG, Xiang HU, Weiwei WANG, Wenbo LEI, Huitong LI, Huaran SUN, Yongqi ZHAN, Zeyu LIAN

“…As the demand for its removal escalates, a strategy involving the modification of natural zeolite (NZ) with sodium hexametaphosphate (SHMP) immersion was employed to enhance its removal efficiency. …”
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Versatile Copper-Chalcogenide-Based Nanoparticles for the Treatment of Brain Diseases by Shuyang Xie, Hualong Liu, Ke Yang, Tingting Wang, Hao Zhang, Zhen Li

“…This review summarizes emerging trends and explores future perspectives on the use of CS NPs for diagnosing and treating central nervous system diseases, including glioblastoma and neurodegenerative disorders.…”
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Dietary formaldehyde: a silent aggravator of diabetes and cognitive impairments by Hanyuan Xu, Haishu Chen, Yihao Li, Tiancheng Luo, Danrui Zhao, Xiaoxiao Chen, Haozhan Zhang, Xinyun Hu, Hui Xu, Yiquan Wang, Yangping Shentu, Zhiqian Tong

“…In this review, we discuss the pivotal role of diet-derived formaldehyde in diabetes and propose that reduction of formaldehyde by the formaldehyde scavengers may be a new strategy for treating DM patients.…”
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Nonmetallic modified zero-valent iron for remediating halogenated organic compounds and heavy metals: A comprehensive review by Zimin Yan, Jia Ouyang, Bin Wu, Chenchen Liu, Hongcheng Wang, Aijie Wang, Zhiling Li

“…Zero-valent iron (ZVI), an ideal reductant treating persistent pollutants, is hampered by issues like corrosion, passivation, and suboptimal utilization. …”
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An ultra low frequency spike timing dependent plasticity based approach for reducing alcohol drinking by Anders J. Asp, Suelen Lucio Boschen, Su-Youne Chang, Jiwon Kim, Jodi L. Silvernail, J. Luis Lujan

“…Our data suggest that GPi/ACC ULF-STDP selectively decreases DMS D1-MSN hyperactivity leading to reduced alcohol consumption without evoking undesired affective behaviors using electrical stimulation rather than approaches requiring genetic modification. This work represents a step towards fulfilling the unmet need for a reliable method of treating severe AUD through cell-type-specific control with clinically available neuromodulation tools.…”
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Bibliometric analysis of rhein in the treatment of tumors by Lan Jiang, Lan Jiang, Lan Jiang, Qian Huang, Zhongquan Shi, Yi Yang

“…However, owing to its poor water solubility, in recent years, functional modification of its functional groups or production of rhein nanoparticles to enhance its bioavailability and antitumor effects has become a hot research direction in the future.…”
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En bloc resection of the ligamentum flavum for bilateral decompression in unilateral biportal endoscopic transforaminal lumbar interbody fusion: a 2-year follow-up study by Chao Li, Beiyu Xu, Yao Zhao, Longtao Qi, Lei Yue, Ranlyu Zhu, Chunde Li, Zhengrong Yu

“…This study has refined UBE-TLIF to incorporate en bloc resection of the ligamentum flavum for bilateral decompression and aim to detail the surgical procedure and evaluate the clinical outcomes of this modification. Methods This study analyzes the outcomes of 109 consecutive patients treated by a single surgeon for lumbar degenerative disease using UBE-TLIF. …”
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Proteomics analysis of body fluid exosomes of rheumatoid arthritis patients underwent oxhorn cupping therapy. by Du Leng, Chimedragchaa Chimedtseren, Tegexibaiyin Wang, Ruga Su, Saren Bao, Xiele Mo, Xigesaiyin Ge, Suna Cha, Runtulaguer Xi, Saqila Wu, RenGaoWa Sa, Jiaqi Zhao, Ren Na, Perenlei Molor-Erdene

“…<h4>Objective</h4>The present study was undertaken to understand the multitarget mechanisms of oxhorn cupping therapy (OHCT) in treating rheumatoid arthritis by proteomic analysis.…”
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Nanobiomaterials-enabled sensors for heavy metal detection and remediation in wastewater systems: advances in synthesis, characterization, and environmental applications by Lata Deso Abo, Hirpha Adugna Areti, Mani Jayakumar, Magesh Rangaraju, Saminathan Subashini

“…Future studies should prioritize optimizing the synthesis, surface modification, and regeneration of NBMs to ensure their scalability and long-term applicability in large-scale treatment systems. …”
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Phenylacetic acid metabolic genes are associated with Mycobacteroides abscessus dominant circulating clone 1 by Brittany N. Ross, Emma Evans, Marvin Whiteley

“…These genes were enriched for functions in sulfur-based DNA modification, DNA integration, and phenylacetic acid (PAA) catabolism. …”
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