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Topical Application of RNAi Therapy Using Surface-Modified Liposomes for Treating Retinal-Vein Occlusion
Published 2025-06-01“…In this study, we present a novel approach to treating retinal diseases using eye drops that contain PnkRNA, a single-stranded RNA nucleic acid. …”
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202
The performance of chemically and physically modified local kaolinite in methanol dehydration to dimethyl ether
Published 2014-09-01“…Natural kaolinite (KN) was treated chemically with H2O2 (KT) followed by thermal treatment at 500 °C (KC) and then mechano-chemically by ball milling with and without CaSO4 (KB-Ca and KB, respectively). …”
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203
Comparative Study Between Native and Modified Starches Isolated from Tamarind Seed
Published 2025-01-01“…Seeds represent a potential source of starch, containing at least 60–70% of total starch, however many of them are treated as waste and are usually discarded. Tamarind seeds known to be high in Xyloglycan. …”
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204
METTL3 promotes podocyte pyroptosis in diabetic nephropathy through N6-methyladenosine modification of TRIM29 mRNA
Published 2025-12-01“…Our results suggest that METTL3 plays a critical role in hyperglycemia-induced podocyte injury through m6A modification of TRIM29 mRNA, which provides new insight for the development of METTL3- and pyroptosis-targeted strategies to treat DN and other diabetic kidney diseases.…”
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205
Esculetin inhibits ferroptosis after ICH by promoting NUDT1-mediated m7G methylation modification of GPX4
Published 2025-08-01“…Inhibiting ferroptosis after ICH will effectively treat ICH and improve prognosis. Esculetin is the main active ingredient of the Chinese medicine Cortex Fraxini, which has neuroprotective effects. 7-methylguanosine (m7G) methylation is a common RNA modification that regulates mRNA stability and translation, playing an important role in neural development and function, as well as in ferroptosis-related pathways. …”
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RBM15 promotes hypoxia/reoxygenation-induced ferroptosis in human cardiomyocytes by mediating m6A modification of ACSL4
Published 2025-07-01“…Methods and results AC16 cells were treated with hypoxia/reoxygenation (H/R) to establish an in vitro myocardial infarction cell model. …”
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207
Effectiveness and Safety of CGRP-Targeted Therapies Combined with Lifestyle Modifications for Chronic Migraine in Korean Pediatric Patients: A Retrospective Study
Published 2025-05-01“…This study evaluated the safety and efficacy of CGRP-targeted therapies combined with structured lifestyle modifications in Korean pediatric patients with CM. <b>Methods:</b> This retrospective study examined 10 pediatric CM patients treated at Gangnam Severance Hospital from 2021 to 2024. …”
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208
Assessment of dental professionals' preparedness for treating patients with special health care needs in Lahore, Pakistan
Published 2024-06-01“…Frequent interactions with SHCN patients were reported by 23.6% (n=52), and 55.5% (n=122) believed there was insufficient experience among dental practitioners in treating these patients. CONCLUSION: The study highlighted a significant knowledge gap and perceived challenges in treating SHCN patients among general dentists. …”
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EFFECT OF POLYMER PROSTHETIC CONSTRUCTION TREATED WITH GLOW-DISCHARGE PLASMA ON ORAL MUCOSA (CLINICAL CASE)
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Enhanced Performance of a Microbial Fuel Cell Using Double Oxidant-Treated Carbon Felts
Published 2025-03-01“…Utilizing double oxidant-treated carbon felts in MFC applications increased current density to 749.56 mA/m<sup>2</sup> and increased peak power density to 125.23 mW/m<sup>2</sup>. …”
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215
The effects of wetting-drying and freezing-thawing cycles on mechanical properties of biopolymer-fiber treated soil
Published 2025-04-01“…Biopolymer-fiber treated soil has great application potential in civil engineering with better mechanical properties and environmental sustainability. …”
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216
Investigating the Histological Changes in Heart, Lung, Liver and Kidney of Male Albino Mice Treated with Ivabradine
Published 2019-09-01“…In Kidney, there are no histopathological modifications in the tissue after the animals treated with 10 mg\kg of Ivabradine. …”
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217
CD19 -targeted CAR T therapy treating hematologic malignancies: hidden danger is the next neighbor to security?
Published 2025-03-01“…In this review, we summarize the short- and long-term toxicity, such as secondary T-cell tumors and lethal CAR tumors, of patients with hematologic malignancies treated with CD19-CAR-T cells, including cytokine release syndrome (CRS), ICANS, and secondary malignancies with low occurrence rates but high mortality, such as secondary T cell tumors and lethal CAR tumors, which may be related to the gene modification mechanism of viral vectors currently approved for CAR-T cells. …”
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The suitability of mesenchymal stem cells for treating immune-mediated inflammatory skin diseases: a systematic review
Published 2025-07-01“…Mesenchymal stem cell (MSC) therapy holds promise for treating immune-mediated inflammatory skin diseases (IMIDs), particularly when conventional therapies are ineffective. …”
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Stem cell-derived exosome delivery systems for treating atherosclerosis: The new frontier of stem cell therapy
Published 2025-02-01“…The design engineering of exosomes has been summarized to present how drug loading and surface modification with targeting ligands can improve the therapeutic and targeting capacity of exosomes, demonstrating atheroprotective action. …”
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