Understanding the Needs and Wishes of Older Adults in Interprofessional Treatment for Malnutrition and Sarcopenia: A Grounded Theory Study by Boxum SD, Van Exter SH, Reinders JJ, Drenth H, Van den Berg MG, Tieland M, Geluk-Bleumink A, Spoorenberg SL, Finnema E, Van der Wees PJ, Koenders N, Jager-Wittenaar H

“…Data collection involved semi-structured interviews and focus groups with community-dwelling older adults who are undergoing treatment or have been treated for (risk of) malnutrition and/or sarcopenia. …”
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Variation in Management of CKD-Associated Pruritus: Results From a Multinational Survey of Kidney Units by Sreeram Venugopal, Daniel V. O’Hara, Neeru Agarwal, Barnaby D. Hole, Charlotte M. Snead, Elizabeth Stallworthy, Fergus J. Caskey, Kathryn Ducharlet, Brendan Smyth

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Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial. by John A Todd, Marina Evangelou, Antony J Cutler, Marcin L Pekalski, Neil M Walker, Helen E Stevens, Linsey Porter, Deborah J Smyth, Daniel B Rainbow, Ricardo C Ferreira, Laura Esposito, Kara M D Hunter, Kevin Loudon, Kathryn Irons, Jennie H Yang, Charles J M Bell, Helen Schuilenburg, James Heywood, Ben Challis, Sankalpa Neupane, Pamela Clarke, Gillian Coleman, Sarah Dawson, Donna Goymer, Katerina Anselmiova, Jane Kennet, Judy Brown, Sarah L Caddy, Jia Lu, Jane Greatorex, Ian Goodfellow, Chris Wallace, Tim I Tree, Mark Evans, Adrian P Mander, Simon Bond, Linda S Wicker, Frank Waldron-Lynch

“…There was an initial learning phase with five pairs of participants, each pair receiving one of five pre-assigned single doses from 0.04 × 106 to 1.5 × 106 IU/m2, in order to model the dose-response curve. …”
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Lesiones musculoesqueléticas atendidas tras la inundación ocurrida en octubre del 2024 en Valencia, España by J.F. Garrido Ferrer, J. Diranzo García, X. Bertó Martí, L. Marco Díaz, L. Hernández Ferrando

“…A total of 84 wounds (20.5% of the sample) and musculoskeletal and ligament injuries (14.4%) were treated, along with joint dislocations (2.4%). The most common injury sites were the lower limbs (48.6%), followed by the upper limbs (36.7%). …”
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Investigating the effectiveness of an intraoperative decision support guided fluid therapy intervention on postoperative outcome of high-risk patients undergoing high-risk abdomina... by Sean Coeckelenbergh, Amelie Delaporte, Damien Rousseleau, Jacques De Montblanc, Stephanie Roullet, Joanna Ramadan, Bernard Cholley, Alexandre Stibon, Emmanuel Weiss, Maria-Christina Kassab, Sylvain Diop, Elsa Manzi, Marco Pustetto, Guillaume Porta Bonette, Pierre Gregoire Guinot, Philippe Guerci, Domien Vanhonacker, Francois Martin Carrier, Brenton Alexander, Joseph Rinehart, David Boldt, Tristan Grogan, Maxime Cannesson, Jacques Duranteau, Lamiae Grimaldi, Bruno Pereira, Alexandre Joosten

“…The Acumen Assisted Fluid Management (AFM) software is a decision support system that uses machine learning to predict fluid responsiveness and individualise fluid therapy. …”
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Multicenter validation of an RNA-based assay to predict anti-PD-1 disease control in patients with recurrent or metastatic head and neck squamous cell carcinoma: the PREDAPT study by Howard L McLeod, A Dimitrios Colevas, Georges Azzi, Kevin C Flanagan, Douglas Adkins, Jessica Ley, Ezra E W Cohen, James Wade, Jon Earls, Jeffrey Hiken, Rachel L Wellinghoff, Michelle M Ponder, William H Westra, Vera Vavinskaya, Leisa Sutton, Ida Deichaite, Orlan K Macdonald, Karim Welaya, Andrew W Pippas, Jennifer Slim, Bruce Bank, Xingwei Sui, Steven E Kossman, Todd D Shenkenberg, Warren L Alexander, Katharine A Price, David N Messina, Jarret I Glasscock, Eric J Duncavage

“…PREDAPT aimed to validate OncoPrism-HNSCC, a clinical biomarker assay predictive of disease control in patients with recurrent or metastatic HNSCC treated with anti-PD-1 immune checkpoint inhibitors as a single agent (monotherapy) and in combination with chemotherapy (chemo-immunotherapy). …”
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Baseline atrial volume indices and major adverse cardiac events following thoracic radiotherapy by Edmund M. Qiao, John He, Katrina D. Silos, Jordan O. Gasho, Patrick Belen, Danielle S. Bitterman, Danielle S. Bitterman, Elizabeth McKenzie, Jennifer Steers, Christian Guthier, Anju Nohria, Michael T. Lu, Hugo J. W. L. Aerts, Hugo J. W. L. Aerts, Hugo J. W. L. Aerts, Andriana P. Nikolova, Raymond H. Mak, Raymond H. Mak, Katelyn M. Atkins, Katelyn M. Atkins

“…We utilized machine learning (ML) to discover novel predictors of MACE and validated them on an external cohort.MethodsThis multi-institutional retrospective study included 984 patients [n = 803 non-small cell lung cancer (NSCLC), n = 181 breast cancer] treated with radiotherapy. …”
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Extended length of stay in open versus minimally invasive surgery with robotic-assisted sub-analysis for spinal nerve sheath tumor resection: a nationwide analysis by Taha Khalilullah, Abdul Karim Ghaith, Xinlan Yang, Shaan Bhandarkar, Linda Tang, Yuanxuan Xia, Richard Crawford, Tej Azad, Jawad Khalifeh, A. Karim Ahmed, Nicholas Theodore, Daniel Lubelski

“…Gradient Boosting had the highest predictive performance among machine learning models (AUC: 0.594), followed by AdaBoost and logistic regression. …”
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Circadian rhythm disruption by PARP inhibitors correlates with treatment toxicity in patients with ovarian cancer and is a predictor of side effectsResearch in context by Deeksha Malhan, Janina Hesse, Nina Nelson, Kay Stankov, Jessica Nguyen, Ouda Aboumanify, Josefin Garmshausen, Gunther Rogmans, Bastian Czogalla, Jens Gerber, Martin Koch, Tomáš Kupec, Oliver Tomé, Ralf Witteler, Mustafa Deryal, Michael Eichbaum, Jalid Sehouli, Elena Ioana Braicu, Angela Relógio

“…These disruptions strongly correlated with the severity and frequency of side effects, including nausea and fatigue, displaying opposite trends between the placebo and rucaparib-treated groups. K-means clustering successfully distinguished rucaparib-treated patients from those receiving placebo based on BMAL1 phase and gene expression profiles. …”
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Association between clinician team segregation, receipt of cardiovascular care and outcomes in valvular heart diseases by Ikeoluwapo Kendra Bolakale‐Rufai, Shannon M. Knapp, Janina Quintero Bisono, Adedoyin Johnson, Wanda Moore, Ekow Yankah, Ryan Yee, Dalancee Trabue, Brahmajee Nallamothu, John M. Hollingsworth, Stephen Watty, Francesca Williamson, Natalie Pool, Megan Hebdon, Nneamaka Ezema, Quinn Capers, Courtland Blount, Nia Kimbrough, Denee Johnson, Jalynn Evans, Brandi Foree, Anastacia Holman, Karen Lightbourne, David Brown, Brownsyne Tucker Edmonds, Khadijah Breathett

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Individually controlled noise reducing devices to improve IEQ in classrooms of primary schools by Dadi Zhang

“…The experiment was conducted in two chambers (acoustically treated chamber and untreated chamber) with different reverberation times (RTs) at the same time. …”
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The impact of early special educational needs provision on later hospital admissions, school absence and education attainment: A target trial emulation study of children with isola... by Vincent Nguyen, Kate Lewis, Ruth Gilbert, Bianca De Stavola, Lorraine Dearden

“…Furthermore, we cannot discount the impact of unaccounted confounding factors, such as parental education and early home learning environments, particularly for the education attainment results.…”
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A mixed methods study protocol for CONFIVAC, an intervention to enhance paediatric nurses' and paediatricians' skills to promote vaccination and vaccine confidence by Elisabet Henderson, Sara Valmayor, Victoria Porthé, Alba Asensio, Xavier Bruna, Usue Elizondo-Alzola, Anna Ramirez-Morros, Gemma Ricós, Josep Vidal-Alaball, M. Isabel Pasarín, Cristina Rius, Elena Roel, Elia Díez

“…PHCWs in the intervention arm will participate in the training program CONFIVAC, which includes 10 h of online learning and 2 h of in-person training featuring role-playing exercises. …”
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Integrating Palliative Care and Heart Failure: the PalliatHeartSynthesis realist synthesis by Tracey McConnell, Carolyn Blair, Geoff Wong, Claire Duddy, Clare Howie, Loreena Hill, Joanne Reid

“…All health and social care staff should work closely together when managing patients with heart failure to learn from each other. Policy, practice and service user champions must be identified and supported to share the benefits of integrated care. …”
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Special Issue on Contemporary Research Studies in Operations Research, Business Analytics, and Business Intelligence by Viswanath Kumar Ganesan, S. Vinodh, Malolan Sundararaman, M. Vimala Rani, M. Mathirajan

“…The results lay the groundwork for developing nano-biosensors to diagnose, treat, and manage cardiovascular disease. The mathematical model had possible scope for target detection and drug delivery at stenosed sites. …”
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Corporate Real Estate alignment by Monique Arkesteijn

“…In all pilot studies the decision makers used the opportunity to either add or remove decision variables and change curves, weights or constraints. The use of such a learning process in the context of work practice and problem solving is described by Schön (1987) as reflection in action. …”
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A group psychological intervention for postnatal depression in British mothers of South Asian origin – the ROSHNI-2 RCT by Nusrat Husain, Karina Lovell, Carolyn A Chew-Graham, Farah Lunat, Penny Bee, Matthias Pierce, Najia Atif, Saadia Aseem, Kamaldeep Bhui, Peter Bower, Traolach Brugha, Nasim Chaudhry, Akbar Ullah, Linda Davies, Nadeem Gire, Deepali Sharma, Jahanara Miah, Waqas Ahmed, Joe Kai, Ilyas Mirza, Jillian Morrison, Naeem Mohmed, Atif Rahman, Shanaya Rathod, Najma Siddiqi, Waquas Waheed, Christopher Williams, Nosheen Zaidi, Richard Emsley, Richard Morriss

“…The results are promising for the wider field, particularly for learning lessons in engagement with this community. …”
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The Ethical Significance of Brain-Computer Interfaces as Enablers of Communication by Toma Gruica

“…The argument culminates in a normative claim: societies have an ethical obligation to maintain and protect communicative capacity where feasible, treating BCIs not merely as therapeutic tools but as infrastructures of moral inclusion. …”
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Enhancing referrals to Child and Adolescent Mental Health Services: the EN-CAMHS mixed-methods study by Kathryn M Abel, Pauline Whelan, Lesley-Anne Carter, Heidi Tranter, Charlotte Stockton-Powdrell, Kerry Gutridge, Lamiece Hassan, Rachel Elvins, Julian Edbrooke-Childs

“…Background National Health Service Child and Adolescent Mental Health Services are specialist teams that assess and treat children and young people with mental health problems. …”
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Healthy Living: Hyperglycemia and Hypoglycemia by Jennifer Hillan, Emily Minton

“…Both can be serious if not treated. Therefore, it’s important to learn about hypoglycemia and hyperglycemia so you can prevent and treat them before they cause health problems. …”
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