Translational medicine research on the role of key gene network modulation mediated by procyanidin B2 in the precise diagnosis and treatment of multiple sclerosis by Jian Liu, Meng Pu, Di Guo, Ying Xiao, Jin-zhu Yin, Dong Ma, Cun-gen Ma, Qing Wang

“…These genes were significantly enriched in biological processes related to oxidative stress and served as potential targets for PCB2 in treating MS. Moreover, a key gene-transcription factor (TFs)-microRNA (miRNA) regulatory network was established to preliminarily explore the upstream regulatory mechanisms of these genes. …”
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From intensive care monitors to cloud environments: a structured data pipeline for advanced clinical decision supportResearch in context by Sijm H. Noteboom, Eline Kho, Maria Galanty, Clara I. Sánchez, Frans C.P. ten Bookum, Denise P. Veelo, Alexander P.J. Vlaar, Björn J.P. van der Ster

“…The availability, agility, computational power, high uptime, and streaming data pipelines allow for large retrospective analyses as well as the opportunity to implement real-time prediction of critical events with machine learning algorithms. Critical events can be accessed by applying keyword search in the natural language data, annotated by the treating team. …”
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Predictive density profile control with discrete pellets, applied to integrated simulations of ITER by C.A. Orrico, M. van Berkel, T.O.S.J. Bosman, L. Ceelen, W.P.M.H. Heemels, F. Koechl, D. Krishnamoorthy

“…We highlight the necessity of treating pellets as discrete events for controller performance and for remaining within density limits. …”
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A digital twin-enabled fog-edge-assisted IoAT framework for Oryza Sativa disease identification and classification by Goluguri N.V. Rajareddy, Kaushik Mishra, Satish Kumar Satti, Gurpreet Singh Chhabra, Kshira Sagar Sahoo, Amir H. Gandomi

“…At the heart of this system lies a sophisticated deep-learning model built on the robust AlexNet neural network architecture. …”
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Robotic Precision vs. Human Dexterity—Benchtop Comparative Study of Free-Hand vs. Robotic-Assisted Puncture in Fluoroscopy-Guided Percutaneous Nephrolithotomy by Jeffery Ze Kang Lim, Chai Chu Ann, Aung Kyaw Phyo, Kanesh Kumaran, Ahmad Nazran, Shanggar Kuppusamy, Teng Aik Ong, Wei Sien Yeoh

“…<b>Introduction:</b> Percutaneous nephrolithotomy (PCNL) is the standard procedure for treating large kidney stones, especially those measuring over 20 mm or staghorn stones. …”
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Omega-3 Fatty Acids: Key Players in Cognitive Function and Brain Health by Wiktoria Wesołowska, Emilia Bachoń, Michalina Doligalska, Aleksandra Stremel, Agnieszka Leszyńska, Julia Linke, Zuzanna Bałoniak, Dominika Kozłowska, Julia Bałoniak, Weronika Tuszyńska

“…Further research is needed to fully understand omega-3s' mechanisms, optimal dosing, and their use in preventing and treating neurological disorders. …”
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AI-driven discovery of synergistic drug combinations against pancreatic cancer by Mohsen Pourmousa, Sankalp Jain, Elena Barnaeva, Wengong Jin, Joshua Hochuli, Zina Itkin, Travis Maxfield, Cleber Melo-Filho, Andrew Thieme, Kelli Wilson, Carleen Klumpp-Thomas, Sam Michael, Noel Southall, Tommi Jaakkola, Eugene N. Muratov, Regina Barzilay, Alexander Tropsha, Marc Ferrer, Alexey V. Zakharov

“…Beyond highlighting the potential of ML, this work delivers 307 experimentally validated synergistic combinations, demonstrating its practical impact in treating pancreatic cancer.…”
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Analisis Minat Belajar Peserta Didik dalam Pembelajaran Sejarah di Kelas X SMA Negeri 16 Samarinda by Adriana Ana, Aulia Rahuma

“… Interest in learning is the main factor that allows students to receive lessons well. …”
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A COMPARATIVE STUDY OF STUDENT’S MATHEMATICAL REPRESENTATION ABILITY USING JIGSAW VS STUDENT FACILITATOR AND EXPLAINING by Merisa Ammelia Sari, Dadan Dasari

“…A random sampling technique was used and two groups were compared, with the experimental group-1 treated with the jigsaw learning model and the experimental group-2 with the student facilitator and explaining learning model. …”
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Ergonomic risk: social representations of dental students by Luana Kelle Batista Moura, Yara Teresinha Correa Silva Sousa, Guilherme César Batista Moura, Francisca Tereza Coelho Matos, Carlos Alberto Monteiro Falcão, Thiago LIma Monte

“…Objective: To learn the social representations of ergonomic risk prepared ​​by dental students. …”
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Ergonomic risk: social representations of dental students by Luana Kelle Batista Moura, Yara Teresinha Correa Silva Sousa, Guilherme César Batista Moura, Francisca Tereza Coelho Matos, Carlos Alberto Monteiro Falcão, Thiago LIma Monte

“…Objective: To learn the social representations of ergonomic risk prepared ​​by dental students. …”
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Predictive modelling and identification of critical variables of mortality risk in COVID-19 patients by Olawande Daramola, Tatenda Duncan Kavu, Maritha J. Kotze, Jeanine L. Marnewick, Oluwafemi A. Sarumi, Boniface Kabaso, Thomas Moser, Karl Stroetmann, Isaac Fwemba, Fisayo Daramola, Martha Nyirenda, Susan J. van Rensburg, Peter S. Nyasulu

“…Aside from clinical methods, artificial intelligence (AI)-based solutions such as machine learning (ML) models have been employed in treating COVID-19 cases. …”
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Efficacy of Cooling Blankets and Cold Fluid Infusions in Classic Heatstroke Treatment: A Controlled Study in Rats by Chen L, Liu C, Zhang Z, Zhang Y, Feng X

“…Lan Chen,1,&ast; Chang Liu,1,&ast; Zhaocai Zhang,2 Yuping Zhang,1 Xiuqin Feng1 1Nursing Department, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310009, People’s Republic of China; 2Department of Critical Care Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310009, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Xiuqin Feng, Nursing Department, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, 310009, People’s Republic of China, Tel +8613757119151, Email fengxiuqin@zju.edu.cnBackground: Rapid core temperature reduction is crucial for treating heatstroke. Clinical methods like cooling blankets and cold fluid infusions are common, but their specific effects are not well defined. …”
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Development of a brain-penetrant G9a methylase inhibitor to target Alzheimer’s disease-associated proteopathology by Ling Xie, Ryan N. Sheehy, Adil Muneer, Yan Xiong, John A. Wrobel, Feng Zhang, Kwang-Su Park, Julia Velez, Jing Liu, Yan-Jia Luo, Brent Asrican, Ping Dong, Ya-Dong Li, Corina Damian, Luis Quintanilla, Yongyi Li, Chongchong Xu, Mohanish Deshmukh, Leon G. Coleman, Guo-Li Ming, Hongjun Song, Zhexing Wen, Jian Jin, Juan Song, Xian Chen

“…Correspondingly, we developed a brain-penetrant inhibitor of G9a, MS1262, which restored both age-related learning & memory and noncognitive functions in multiple AD mouse models. …”
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The role of a tutor in teaching values by Anna Pekala

“…A young person growing up in an environment where human values ​​are respected and transmitted, learns about proper relationship with the others, understands the meaning of human existence, recognizes the value of work, culture, learns empathy, how to respect and how to be responsible. …”
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Prophylactic IL-23 blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy by Ting Chen, Lin Zhao, Jiaojiao Zhang, Mingyi Ju, Zhuoyuan Deng, Minjie Wei, Lianghua Ma

“…Background Immune-related adverse events (irAEs), characterized by targeted inflammation, occur in up to 60% of patients with melanoma treated with immune checkpoint inhibitors (ICIs). …”
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The implementation of the situational control concept of information security in automated training systems by A. M. Chernih, S. V. Fedoseev

“…It is assumed that the automated learning system is a fragment of a larger information system that contains several information paths, each of them treats different information in the protection degree from information, containing constituting state secrets, to open access information.It is considered that the technical methods, measures and means of information protection in automated learning systems implement less than half (30%) functions of subsystems of control and protection information. …”
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دور مراکز التعلم فى دعم العملية التعليمية فى الوطن العربى : مراجعة علمية by عادل سيف الکمزاوى

“…To clarify the total and partialrelationship of the studies he reviews, and to treat each study a new idea, worthyof reading and review, and having a close relationship with the research topic.The most important results of this review were: Insufficient resources and financial allocations to transform libraries intoresource centers for learning, and the lack of representation of libraries inplanning committees and major forums to support them and turn them intoa resource center for learning. The strongest justification for changing the name of school libraries intolearning resource centers is the process of integrating school libraries witheducational aids, given that both information sources and educational aidsare sources of learning, and the factors that lead to increasing theeffectiveness of the learning resource center are the most important ofwhich are: qualified workers, the appropriate building and materialfacilities, and the budget Of the center, and the availability of informationsources of all kinds and forms. Librarians face many obstacles due to the lack of a job description that fitstheir work in the LRC, which results in the absence of qualified staff as aspecialist in LRC.…”
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EFEKTIVITAS PLATFORM DIGITAL BERBASIS GOOGLE SLIDE TERHADAP HASIL BELAJAR PADA PEMBELAJARAN PENDIDIKAN AGAMA ISLAM DI SEKOLAH DASAR by Royyanatul Mahbubah Suharto, Rofiatul Hosna Hosna

“…And educators are competing to present innovations and new colors in learning. Technology is very helpful in the learning process, the material is so easy to get, training or the learning process can be done online or anywhere, one of which is through the Google Slides platform. …”
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Ergonomic risk: social representations of dental students by Luana Kelle Batista Moura, Yara Teresinha Correa Silva Sousa, Guilherme César Batista Moura, Francisca Tereza Coelho Matos, Carlos Alberto Monteiro Falcão, Thiago LIma Monte

“…Objective: To learn the social representations of ergonomic risk prepared ​​by dental students. …”
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