An Analysis for IDH‐Mutant Grade 4 Astrocytoma Based on WHO CNS 5: Implication of Clinical Practice by Xianxin Qiu, Liping Liang, Lingchao Chen, Pengjie Hong, Wanzun Lin, Jiabing Liu, Zhirui Zhou, Wenjia Zhu, Tianqi Wu, Mingyuan Pan, Yihua Zhong, Jing Gao, Zhiyong Qin, Yang Wang

“…Eleven patients received adjuvant tumor‐treating fields (TTFields). Results The median follow‐up was 15.7 months. …”
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Soil suction dataset from a lime & cement treated embankment, from 2010 to 2023 by Yasmina Boussafir, Dimitri Mercadier, Christophe Piquet

“…Other sensors recorded the volumetric water content only, in the core of the embankment, its base and the platform [3]. All data are available from 2010 to 2023. A weather station recorded precise meteorological data from 2010 to 2013.The goal of this real size embankment was to evaluate the sustainability of treated soils used in earth structures and to test the re-use of very plastic clay thanks to adapted soil treatment. …”
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Retrospective study of onychomycosis patients treated with ciclopirox 8% HPCH and oral antifungals applying artificial intelligence to electronic health records by Gastón Roustan, José Luis López Estébaranz, Pablo De La Cueva, Savana Research Group, Francesca Pajuelo, María Luisa Tamarit, Aida Valmaseda, Jordi Galván

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Preventive strategies and factors associated with surgically treated necrotising enterocolitis in extremely preterm infants: an international unit survey linked with retrospective cohort data analysis by Dirk Bassler, Kei Lui, Michael Dunn, Victor Samuel Rajadurai, Mikael Norman, Alejandro Avila-Alvarez, Marc Beltempo, Mark Adams, Barbara Bajuk, Malcolm Battin, Jean-François Tolsa, Ruben Alvaro, Chuks Nwaesei, Martine Claveau, Shoo K Lee, Prakesh S Shah, Zenon Cieslak, Rebecca Sherlock, Wendy Yee, Carlos Fajardo, Zarin Kalapesi, Koravangattu Sankaran, Mary Seshia, Amit Mukerji, Orlando Da Silva, Kyong-Soon Lee, Brigitte Lemyre, Kimberly Dow, Ermelinda Pelausa, Keith Barrington, Christine Drolet, Bruno Piedboeuf, Valerie Bertelle, Edith Masse, Roderick Canning, Hala Makary, Cecil Ojah, Luis Monterrosa, Jehier Afifi, Andrzej Kajetanowicz, lex Doyle, Roland Broadbent, Ross Haslam, Peter Marshall, Peter Schmidt, Paul Craven, Koert De Waal, Karen Simmer, Andy Gill, Jacqueline Stack, Dan Casalaz, Jim Holberton, Lucy Cooke, Lyn Downe, Michael Stewart, Andrew Berry, Rod Hunt, Charles Kilburn, Tony De Paoli, Mary Paradisis, Ingrid Rieger, Pieter Koorts, Carl Kuschel, Andrew Numa, Hazel Carlisle, Nadia Badawi, Guan Koh, Melissa Luig, Chad Andersen, Adrienne Lynn, Brian Darlow, Lindsay Mildenhall, Mariam Buksh, David Bourchier, Vaughan Richardson, Georgina Chambers, Robert Halliday, Thomas Riedel, Anne Synnes, Amir Kugelman, W Coroleu, Liisa Lehtonen, Brian A Darlow, Brian Reichman, Stellan Hakansson, Kjell K Helenius, Laura San Feliciano, Maximo Vento, Marco Moroni, Junmin Yang, Adam Buckmaster, Charles Barfield, Vijay Shingde, Shelley Reid, David Cartwright, Steven Resnick, Jutta van den Boom, Lee Carpenter, Adele Harrison, Khalid Aziz, Akhil Deshpandey, Sture Andersson, Outi Tammela, Ulla Sankilampi, Timo Saarela, Eli Heymann, Shmuel Zangen, Tatyana Smolkin, Francis Mimouni, David Bader, Avi Rothschild, Zipora Strauss, Clari Felszer, Hussam Omari, Smadar Even Tov-Friedman, Benjamin Bar-Oz, Michael Feldman, Nizar Saad, Orna Flidel-Rimon, Meir Weisbrod, Daniel Lubin, Ita Litmanovitz, Eric Shinwell, Gil Klinger, Yousif Nijim, Alona Bin-Nun, Agneta Golan, Dror Mandel, Vered Fleisher-Sheffer, David Kohelet, Lev Bakhrakh, José Luis Fernandez-Trisac, Ma Luz Couce Pico, María José Fernández Seara, Andrés Martínez Gutiérrez, Carolina Vizcaíno, Miriam Salvador Iglesias, Honorio Sánchez Zaplana, Belén Fernández Colomer, José Enrique García López, M Rafael García Mozo, Teresa González Martínez, Mª Dolores Muro Sebastián, Marta Balart Carbonell, Joan Badia Barnusell, Mònica Domingo Puiggròs, Corporacio Parc Taulí, Josep Figueras Aloy, Francesc Botet Mussons, Israel Anquela Sanz, Gemma Ginovart Galiana, Martin Iriondo, Laura Castells Vilella, Roser Porta, Xavier Demestre, Silvia Martínez Nadal, Cristina de Frutos Martínez, María Jesús López Cuesta, Dolores Esquivel Mora, Joaquín Ortiz Tardío, Isabel Benavente, Almudena Alonso, Ramón Aguilera Olmos, Miguel A García Cabezas, Mª Dolores Martínez Jiménez, Mª Pilar Jaraba Caballero, Mª Dolores Ordoñez Díaz, Alberto Trujillo Fagundo, Lluis Mayol Canals, Fermín García-Muñoz Rodrigo, Lourdes Urquía Martí, María Fernanda Moreno Galdo, José Antonio Hurtado Suazo, Eduardo Narbona López, José Uberos Fernández, Miguel A Cortajarena Altuna, Oihana Muga, David Mora Navarro, María Teresa Domínguez, Mª Yolanda Ruiz del Prado, Inés Esteban Díez, María Teresa Palau Benavides, Santiago Lapeña, Teresa Prada, Eduard Soler Mir, Araceli Corredera Sánchez, Enrique Criado Vega, Náyade del Prado, Cristina Fernández, Lucía Cabanillas Vilaplana, Irene Cuadrado Pérez, Luisa López Gómez, Laura Domingo Comeche, Isabel Llana Martín, Carmen González Armengod, Carmen Muñoz Labián, Mª José Santos Muñoz, Dorotea Blanco Bravo, Vicente Pérez, Mª Dolores Elorza Fernández, Celia Díaz González, Susana Ares Segura, Manuela López Azorín, Ana Belén Jimenez, Tomás Sánchez-Tamayo, Elías Tapia Moreno, María González, Beatriz Vacas del Arco, Josefina Márquez Fernández, Laura Acosta Gordillo, Mercedes Granero Asensio, Carmen Macías Díaz, Mar Albújar, Pedro Fuster Jorge, Sabina Romero, Ana Belén Escobar Izquierdo, Javier Estañ Capell, Mª Isabel Izquierdo Macián, Mª Mar Montejo Vicente, Raquel Izquierdo Caballero, Mª Mercedes Martínez, Aintzane Euba, Amaya Rodríguez Serna, Juan María López de Heredia Goya, Alberto Pérez Legorburu, Ana Gutiérrez Amorós, Víctor Manuel Marugán Isabel, Natalio Hernández González, Segundo Rite Gracia, Mª Purificación Ventura Faci, Mª Pilar Samper Villagrasa, Jiri Kofron, Katarina Strand Brodd, Andreas Odlind, Lars Alberg, Sofia Arwehed, Ola Hafström, Anna Kasemo, Karin Nederman, Lars Åhman, Fredrik Ingemarsson, Henrik Petersson, Pernilla Thurn, Eva Albinsson, Bo Selander, Thomas Abrahamsson, Ingela Heimdahl, Kristbjorg Sveinsdottir, Erik Wejryd, Anna Hedlund, Maria Katarina Söderberg, Boubou Hallberg, Thomas Brune, Jens Bäckström, Johan Robinson, Aijaz Farooqi, Erik Normann, Magnus Fredriksson, Anders Palm, Urban Rosenqvist, Bengt Walde, Cecilia Hagman, Andreas Ohlin, Rein Florell, Agneta Smedsaas-Löfvenberg, Philipp Meyer, Claudia Anderegg, Sven Schulzke, Mathias Nelle, Bendicht Wagner, Grégoire Kaczala, Riccardo E Pfister, Matthias Roth, Martin Stocker, Bernhard Laubscher, Andreas Malzacher, John P Micallef, Lukas Hegi, Romaine Arlettaz, Carlo Dani, Patrizio Fiorini, Paolo Ghirri, Barbara Tomasini, Franca Rusconi

“…Objectives To compare necrotising enterocolitis (NEC) prevention practices and NEC associated factors between units from eight countries of the International Network for Evaluation of Outcomes of Neonates, and to assess their association with surgical NEC rates.Design Prospective unit-level survey combined with retrospective cohort study.Setting Neonatal intensive care units in Australia/New Zealand, Canada, Finland, Israel, Spain, Sweden, Switzerland and Tuscany (Italy).Patients Extremely preterm infants born between 240 to 286 weeks’ gestation, with birth weights<1500 g, and admitted between 2014–2015.Exposures NEC prevention practices (probiotics, feeding, donor milk) using responses of an on-line pre-piloted questionnaire containing 10 questions and factors associated with NEC in literature (antenatal steroids, c-section, indomethacin treated patent ductus arteriosus and sepsis) using cohort data.Outcome measures Surgical NEC rates and death following NEC using cohort data.Results The survey response rate was 91% (153 units). …”
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Analyzing Changes in Amino Acid Blood Metabolites and Developmental Data in Children Aged 24–59 Months Treated for Malnutrition With and Without Rice Bran Supplementation by Emma S Bovaird, Moretta D Fauzi, Damayanti D Soekarjo, Sahar B Toulabi, Annika M Weber, Frank T Wieringa

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Quality of life of treated opiate addicts in the methadone maintenance program and those treated with buprenorphine by Marinković Mirjana, Đorđević-Jovanović Lidija, Miljković Snežana, Milojković Bobana, Janjić Vladimir

“…The aim of this study was to determine which addicts characteristics, as well as the characteristics of the addiction and treatment have predicative influence on the quality of life of the opiate addicts treated in the methadone maintenance program and those treated with buprenorphine. …”
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Acute Myeloid Leukemia: To Treat or Not to Treat – Experience from a Resource-limited Setting by Kaladada I. Korubo, Akpevwe Deborah Maduka, Emmanuel Wobo, Gracia Ekeh, Hannah E. Omunakwe, Linda Anucha Dublin-Green, Chijioke Adonye Nwauche

“…MATERIALS AND METHODS: A 5-year retrospective study was conducted in two tertiary healthcare facilities in Nigeria. Data were retrieved from the case files of patients diagnosed with AML from July 2016 to June 2021. …”
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Treating rheumatoid arthritis to target: Revision of the 2014 International Expert Group Recommendations by N. T. Vatutin, E. V. Sklyannaya, G. G. Taradin, A. S. Smirnova, M. A. El-Khatib

“…The revised recommendations consider the results of numerous randomized controlled and cohort studies, as well as the data of an extensive systematic review of the literature. …”
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Efficacy and safety of co-administered ivermectin plus albendazole for treating soil-transmitted helminths: A systematic review, meta-analysis and individual patient data analysis. by Marta S Palmeirim, Eveline Hürlimann, Stefanie Knopp, Benjamin Speich, Vicente Belizario, Serene A Joseph, Michel Vaillant, Piero Olliaro, Jennifer Keiser

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Prognostic Value of KRAS/TP53 Status for Overall Survival in First-Line Monoimmunotherapy and Chemoimmunotherapy Treated Patients With Nonsquamous NSCLC in the Netherlands: A Brief... by Vincent D. de Jager, MD, Léon C. van Kempen, PhD, Betzabel N. Cajiao Garcia, MSc, T. Jeroen N. Hiltermann, MD, PhD, Anthonie J. van der Wekken, MD, PhD, Ed Schuuring, PhD, Stefan M. Willems, MD, PhD

“…In a separate analysis of treatment subgroups, mutated TP53 was associated with longer median OS in chemoimmunotherapy treated KRAS-wildtype patients (468 versus 341 d, HR = 0.71, p = 0.029) but not in monoimmunotherapy treated patients with KRAS-wildtype (512 versus 371 d, HR = 0.91, p = 0.78). …”
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Descriptive analysis of durvalumab use in unresectable stage III non-small cell lung cancer in patients treated in Quebec’s University teaching hospitals by Valérie Labrie, Judith Lefebvre, Catherine Labbé, Kevin Jao, Mandy Malick, Serge Simard, Nicole Bouchard

“…Median PFS was 40 months in patients treated with CRT + durvalumab vs 6.9 months with CRT alone, with a hazard ratio (HR) of 0.22 (95% confidence interval (CI) 0.13-0.37; p < 0.0001). …”
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Subclinical hypothyroidism: treat or watch? by I. A. Tsanava, S. V. Bulgakova, A. V. Melikova

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Real-World-Data of Treatment-Naïve and Previously Treated Patients Receiving Up to 3 Injections of Faricimab in Neovascular Age-Related Macular Degeneration by Kunzmann BC, Schweig AS, Bartz-Schmidt KU, Sobolewska B

“…Demographic data, treatment history, best corrected visual acuity (BCVA), anatomic parameters, and adverse events (AEs) were collected.Results: After one IVI of faricimab, previously treated (n=160) eyes with a mean of 33.51 IVIs and treatment-naïve (n=10) eyes showed a mean BCVA gain of +0.59± 0.52 letters (p=0.364) and +5.00± 6.50 letters (p=0.461), respectively, and a mean central subfield thickness (CST) reduction of − 27.65± 5.33 μm (p< 0.001) and − 94.10± 39.74 μm (p=0.042), respectively. …”
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Using chemotherapy against metastatic pancreatic neuroendocrine neoplasm: how aggressively do we treat it? Real world data from a Brazilian Cancer Center by Mauro Daniel Spina Donadio, Victor Hugo Fonseca de Jesus, Milton José Barros

“…Conclusion: Our real world data shows that doublet platin is a preferred and active schema for treating pNEN, especially in first and second line. …”
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Coverage and contextual factors associated with insecticide-treated net use among women of reproductive age in Nigeria: evidence from the 2021 malaria indicator survey data. by Amadou Barrow, Oluwakemi Christie Ogidan, Chimezie Igwegbe Nzoputam, Michael Ekholuenetale

“…We conducted a secondary data analysis of the 2021 Malaria Indicator Survey (NMIS). …”
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A predictive model for functional cure in chronic HBV patients treated with pegylated interferon alpha: a comparative study of multiple algorithms based on clinical data by Ya-mei Ye, Yong Lin, Fang Sun, Wen-yan Yang, Lina Zhou, Chun Lin, Chen Pan

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Evaluation of Healthcare Outcomes of Patients Treated with 3D-Printed-Titanium and PEEK Cages During Fusion Procedures in the Lumbar Spine by Corso KA, Teferra AA, Michielli A, Corrado K, Marcini A, Lotito M, Smith C, Costa M, Ruppenkamp J, Wallace A

“…Katherine A Corso,1 Andreas A Teferra,1 Annalisa Michielli,2 Kristin Corrado,2 Amy Marcini,3 Mark Lotito,2 Caroline Smith,4 Michelle Costa,4 Jill Ruppenkamp,1 Anna Wallace1 1MedTech Epidemiology and Real-World Data Science, Johnson & Johnson, Raynham, Massachusetts & New Brunswick, New Jersey, USA; 2Clinical Research, DePuy Synthes, MedTech, Johnson & Johnson, Raynham, Massachusetts, USA; 3Medical Affairs, DePuy Synthes, MedTech, Johnson & Johnson, Raynham, Massachusetts, USA; 4Franchise HEMA, DePuy Synthes, Medtech, Johnson & Johnson, Raynham, Massachusetts, USACorrespondence: Katherine A Corso, MedTech Epidemiology and Real-world Data Science, Johnson & Johnson, 325 Paramount Drive, Raynham, MA, 02767, USA, Tel +1 857-523-0279, Email kcorso1@its.jnj.comPurpose: The objective of this observational, real-world study was to describe reoperation, revision, index healthcare utilization and hospital costs among patients treated with PEEK (polyetheretherketone) or 3D-printed-titanium cages during lumbar/lumbosacral posterior fusion procedures, either TLIF (transforaminal lumbar interbody fusion) or PLIF (posterior lumbar interbody fusion). …”
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CLINICIAN — TREATS, AND PATIENT — BEING TREATED? RECENT VIEW ON THE TREATMENT ADHERENCE IN CORONARY HEART DISEASE SETTING by О. Yu. Shaydyuk, М. А. Kudinova, Е. О. Taratukhin, О. V. Romashenko

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Treating osteoarthrosis in terms of the safety of pharmacotherapy by A E Karateyev

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Are payers treating orphan drugs differently? by Joshua P. Cohen, Abigail Felix

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