A comparison of healthcare resource utilization and costs between patients with chronic lymphocytic leukemia treated with first-line ibrutinib or acalabrutinib using two large US r... by Kerry A Rogers, Benyam Muluneh, Zaina P Qureshi, Jinghua He, Alex Bokun, Zhijie Ding, Marie-Helene Lafeuille, Priyanka Gogna, Bruno Emond, Michael Fradley

“…Conclusion: In this large real-world study using a mix of claims data and imputed cost estimates, CLL/SLL patients treated with ibrutinib had longer duration of 1L, fewer days with CLL/SLLrelated outpatient services and numerically lower all-cause and CLL/SLL-related costs versus acalabrutinib, showing that ibrutinib can be an optimal cost-effective option in 1L.…”

Imputation and Missing Indicators for Handling Missing Longitudinal Data: Data Simulation Analysis Based on Electronic Health Record Data by Molly Ehrig, Garrett S Bullock, Xiaoyan Iris Leng, Nicholas M Pajewski, Jaime Lynn Speiser

“… Abstract BackgroundMissing data in electronic health records are highly prevalent and result in analytical concerns such as heterogeneous sources of bias and loss of statistical power. …”
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RIDDEN: Data-driven inference of receptor activity from transcriptomic data. by Szilvia Barsi, Eszter Varga, Daniel Dimitrov, Julio Saez-Rodriguez, László Hunyady, Bence Szalai

“…We also show that RIDDEN can be used to identify mechanistic biomarkers in an immune checkpoint blockade-treated cancer patient cohort. RIDDEN, the largest transcriptomics-based receptor activity inference model, can be used to identify cell populations with altered receptor activity and, in turn, foster the study of cell-cell communication using transcriptomics data.…”
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PROTEST AGAINST STEREOTYPE THREATS REFLECTED IN TONI MORRISON’S THE BLUEST EYE NOVEL by Ahmad Imam Muzaqi

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Intravenous Fosfomycin for Difficult-to-Treat Infections: A Real-Life Multicentric Study in Italy by Verena Zerbato, Gianfranco Sanson, Lisa Fusaro, Valentina Gerussi, Sara Sincovich, Fabiana Dellai, Giovanni Del Fabro, Nicholas Geremia, Cristina Maurel, Donatella Giacomazzi, Chiara Biasinutto, Filippo Giorgio Di Girolamo, Gianfranco Scrivo, Venera Costantino, Manuela Di Santolo, Marina Busetti, Lory Saveria Crocè, Simone Giuliano, Massimo Crapis, George Zhanel, Carlo Tascini, Roberto Luzzati, Stefano Di Bella

“…While widely used in severe infections, real-world data on intravenous fosfomycin remain limited. <b>Objectives:</b> This study aimed to describe the clinical and microbiological characteristics of patients treated with intravenous fosfomycin and to analyze its administration modalities in a real-world setting. …”
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EVALUATION OF IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH POSTTRAUMATIC OSTEOARTHROSIS TREATED WITH RADON THERAPY by E. Yu. Udartsev

“…Following treatment including radon therapy, a significant trend for normalization of all the studied immunological data was observed in majority of patients. The findings provide further evidence for application of radon therapy, in order to treat patients with posttraumatic inflammatory changes of the joint cavity.…”
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Hematological parameter changes and associated factors in neonates with hyperbilirubinemia treated with phototherapy by Adamu Kassie, Dereje Mengesha Berta, Aregawi Yalew, Chomaw Sitotaw, Mickael Workineh, Berhanu Woldu

“…Blood samples were collected before and after phototherapy. Data were entered into Epi-data (4.6.0) and analyzed using SPSS (25.0). …”
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Significant Progress in CAR T-Cell Therapy for Difficult-to-Treat Hematologic Malignancies by Raphaël Stadelmann, Anne Cairoli, Caroline Arber

“…Here the latest data on commercially available CAR T-cell therapies are summarized and discussed. …”
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Influence of hypothyroidism on renal function&amp;nbsp;of lithium-treated patients by Lozano R, Marín R, Santacruz M

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Antibiotic Use and Survival in Patients With Late-Stage NSCLC Treated With Chemoimmunotherapy by Emanuela Taioli, MD, PhD, Raja M. Flores, MD, Arwa Abdelhamid, MPH, Matthew Untalan, MPH, Tara Ivic-Pavlicic, MPH, Stephanie Tuminello, PhD, MPH

“…Methods: We have analyzed antibiotic use in patients with stage IV first, primary NSCLC diagnosed in 2015 and treated with chemotherapy or chemoimmunotherapy, drawn from the Surveillance, Epidemiology, and End Results-Medicare data set. …”
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Investigation of the nature of defects on the outer surface of heat-treated seamless pipes by O. V. Rozhkova

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Radiation pneumonitis in lung cancer patients treated with chemoradiation plus durvalumab by Narek Shaverdian, Maria Thor, Annemarie F. Shepherd, Michael D. Offin, Andrew Jackson, Abraham J. Wu, Daphna Y. Gelblum, Ellen D. Yorke, Charles B. Simone II, Jamie E. Chaft, Matthew D. Hellmann, Daniel R. Gomez, Andreas Rimner, Joseph O. Deasy

“…Conclusions Our data suggest a delayed onset of RP in patients treated with cCRT and durvalumab vs cCRT alone, and for RP to develop in a greater number of patients treated with cCRT and durvalumab. …”
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Toll-like Receptor 4 Modulation as a Strategy to Treat Sepsis by X. Wittebole, D. Castanares-Zapatero, P. F. Laterre

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Sex as modifier of survival in patients with advanced urothelial cancer treated with pembrolizumab by Lorena Incorvaia, Sarah Scagliarini, Fernando Sabino Marques Monteiro, Hideki Takeshita, Jose Carlos Tapia, María Natalia Gandur Quiroga, Elaine Lam, Deniz Tural, Lazar Popovic, Saul Campos-Gomez, Paolo Andrea Zucali, Augusto Mota, Cinzia Ortega, Juan Pablo Sade, Mimma Rizzo, Ondřej Fiala, Nuno Vau, Patrizia Giannatempo, Halima Abahssain, Andrea Benedetto Galosi, Giuseppe Badalamenti, Jindrich Kopecky, Aristotelis Bamias, Johannes Landmesser, Jawaher Ansari, Fabio Calabrò, Francesco Massari, Sebastiano Buti, Joaquim Bellmunt, Matteo Santoni

“…Our data showed that women with metastatic urothelial carcinoma treated with pembrolizumab had shorter OS than men, with a 13% advantage in the 5-year OS rate for male patients. …”
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Would you rather treat? A rare case of Mycobacterium scrofulaceum by Junaid Zafar Sheikh, Nonhlanhla Lunjani, Hira Gul, Louay Kila, Brian Casserly

“…Due to lack of empirical data for guidance, treatment approaches at this juncture remain unclear. …”
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Influence of Different Obturation Systems on the Fracture Resistance of Endodontically Treated Roots by Mazen Doumani, Saleem Abdulrab, Abdulaziz Samran, Ahmed Doumani, Kinda Layous, Mutlu Özcan

“… Objective: This study aimed to compare the fracture resistance of endodontically treated roots filled by different obturation systems. …”
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Outcomes from intracerebral hemorrhage among patients pre-treated with statins by Flávio Ramalho Romero, Eduardo de Freitas Bertolini, Vanessa Nogueira Veloso, Leandro Venturini, Eberval G. Figueiredo

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Effects of Different Magnetically Treated Waters on Emergence and Growth of Snail Medic by Saeed Sharafi, Mohsen Nasrabadi, Mohammad Javad Nahvinia

“…The number of seedlings emerged was counted on daily basis, whereas growth data was measured on the 20th day after planting. …”
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Gender-related Differences in Surgically Treated Patients with Renal Cell Carcinoma by İlker Akarken, Yelda Dere, Hüseyin Tarhan, Hasan Deliktaş, Hayrettin Şahin

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Methotrexate Reduced TNF Bioactivity in Rheumatoid Arthritis Patients Treated with Infliximab by Delphine Dénarié, Mélanie Rinaudo-Gaujous, Thierry Thomas, Stéphane Paul, Hubert Marotte

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