Enhanced beta power emerges from simulated parkinsonian primary motor cortex by Donald W. Doherty, Liqiang Chen, Yoland Smith, Thomas Wichmann, Hong-Yuan Chu, William W. Lytton

“…Dysfunction in PT5B neurons, the final-common-pathway to brainstem and spinal cord, provides a new target to treat PD motor symptoms.…”
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COVID-19-Associated Biventricular Takotsubo Syndrome Complicated with Cardiogenic Shock (Clinical Case) by E. M. Zeltyn-Аbramov, N. I. Belavina, N. N. Klochkova, R. T. Iskhakov, O. Yu. Evsyukov, L. Yu. Аrtyukhina, A. M. Svanadze, M. A. Lysenko

“…The presented case demonstrates a life-threatening TS pattern in patients with severe COVID-19. TPE procedure should be treated as a possible trigger of TS.…”
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THE INFLAMMASOME DRIVES MICROVASCULAR IMPAIRMENT IN MOUSE MODELS OF INTRAVASCULAR HEMOLYSIS by PL Brito, EMFG Azevedo, LFS Gushiken, FC Leonardo, FF Costa, N Conran

“…Moreover, NLRP3 inflammasome inhibition reduced leukocyte recruitment to the venule walls of HEM mice, indicating an improvement in hemolysis-induced microvascular dysfunction. This was further corroborated by LDF, which showed improved blood perfusion in the skin of MCC950-treated HEM mice. …”
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The Effects of Caffeine Toxicity on The Liver in WistarRats by Innih, S.O.*, Calmday-Ombo, D.

“…The data obtained from this study suggests that Caffeine induces hepatotoxicity in ascending manner of dose- dependent pattern in adult Wistar rats.…”
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A Case Report of IgG4-related Disease With Common Clinical Manifestation in an Atypical Gender by Seyed Reza Najafizadeh, Maryam Yaseri

“…Background IgG4-related disease (IgG4-RD) is a recently described clinicopathological condition with a wide range of clinical manifestations including a dense lymphoplasmacytic infiltrate rich in IgG4positive plasma cells, fibrosis arranged in a storiform pattern, obliterative phlebitis, and elevated serum IgG4 concentrations. …”
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The prevalence and correlates of low sexual functioning in women on hemodialysis: A multinational, cross-sectional study. by Valeria Saglimbene, Patrizia Natale, Suetonia Palmer, Marco Scardapane, Jonathan C Craig, Marinella Ruospo, Letizia Gargano, Giuseppe Lucisano, Marietta Török, Eduardo Celia, Rubén Gelfman, Anna Bednarek-Skublewska, Jan Dulawa, Paul Stroumza, Miguel Leal, Domingo Del Castillo, Angelo Marco Murgo, Staffan Schon, Charlotta Wollheim, Jörgen Hegbrant, Giovanni F M Strippoli

“…The aim of this study was to assess prevalence and correlates of the individual domains of sexual functioning in women treated with hemodialysis. We recruited, into this multinational cross-sectional study, women treated with long-term hemodialysis (Collaborative Working Group on Depression and Sexual dysfunction in Hemodialysis study). …”
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From hypertension to heart failure: The missed clues of transthyretin cardiac amyloidosis by Ambreen Gul, Kamran Dawood

“…NT-proBNP increased to 1204 ng/L, and cardiac troponin was mildly elevated at 28 ng/L.Electrocardiography (ECG) demonstrated a pseudo-infarct pattern (Fig 1). Repeat echocardiography revealed severe LVH with a restrictive filling pattern, raising suspicion of an infiltrative cardiomyopathy, such as cardiac amyloidosis. …”
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Sexual Motivation (Desire): Problems with Current Preclinical and Clinical Evaluations of Treatment Effects and a Solution by Anders Ågmo

“…There has been an extensive search for efficient pharmacological treatment of female sexual interest/arousal disorder and other sexual dysfunctions. However, available treatments have met limited success, except for the drugs used for treating erectile deficiency. …”
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Clinical, pathogenetic and prognostic value of diabetic retinopathy’s progression after phacoemulsification in patients with the essential hypertension by N. S. Khodjaev, V. V. Chernikh, K. E. Kuntysheva

“…All identified laboratory patterns were confirmed by the parallel dynamic prospective ophthalmic studies that demonstrated a higher incidence of vascular disorders after phacoemulsification in patients with diabetic retinopathy and hypertension who were not taking ACE inhibitors. …”
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The dual GLP-1 and GIP receptor agonist tirzapetide provides an unintended interaction with the β-adrenoceptors and plays a role in glucose metabolism in hyperglycemic or senescent... by Dunya Aydos, Zeynep Busra Aksoy, Mehmet Altay Unal, Kamil Can Akcali, Ceylan Verda Bitirim, Belma Turan

“…Methods To establish the multifaceted cardioprotective function and underlying mechanisms of TZPD against hyperglycemia (HG)—or senescence (SC)-induced cardiac dysfunction, H9c2 cells were treated with and without TZPD. …”
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Oral High-Dose Thiamine Improves the Symptoms of Chronic Cluster Headache by Costantini Antonio, Tiberi Massimo, Zarletti Gianpaolo, Pala Maria Immacolata, Trevi Erika

“…Cluster headache is a rare painful primary disorder occurring in either episodic or chronic patterns. Several authors found that the hypothalamus, the brain region regulating endocrine function and autonomic system, is involved in the pathophysiology of cluster headache. …”
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Activated PRDM1-CREBBP contributes to preeclampsia by regulating apoptosis and invasion of the human trophoblast cells by Xuan Zhang, Lei Sun

“…High-throughput mRNA sequencing (RNA-seq) was performed to analyze the gene expression patterns in placentas from patients with early-onset PE (EOPE). …”
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Adherence to clinical guidelines for the evaluation and management of eosinophilic esophagitis among gastroenterologists in the Arab countries by Abdulrahman Al-Hussaini, Abdulrahman Al-Hussaini, Abdulrahman Al-Hussaini, Jaber Alrashidi, Mohamad Miqdady, Rana Bitar, Isamme AlFayyad

“…BackgroundThe practice patterns of eosinophilic esophagitis (EoE) remain poorly characterized. …”
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Features of functional state restoration among military personnel after traumatic brain injury combined with acubarotrauma by A. V. Shvets, Yu. V. Podolian, M. I. Holinko

“…A discriminant model allows to reliably (P < 0.001) determine patterns of informative characteristics of functional state in patients with concussion and those who additionally had acubarotrauma on admission to the hospital. …”
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NEUROPSYCHIATRIC DISORDERS IN JUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: RESULTS FROM A RETROSPECTIVE STUDY by M. I. Kaleda, I. P. Nikishina, S. I. Glukhova, N. Yu. Stepanenko

“…There was a preponderance of central nervous system lesion (89%) in the pattern of neuropsychiatric manifestations. Fifteen (33.3%) patients had more than one manifestation of neurolupus. …”
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Identification of a metabolic brain network characterizing essential tremor by Solange Volnov, Hamzah Baagil, Oliver Winz, Hans-Juergen Kaiser, Sanne Katherina Meles, Joerg Bernhard Schulz, Kathrin Reetz, Felix Manuel Mottaghy, Florian Holtbernd

“…The ET related metabolic spatial covariance pattern (ETRP) was characterized by relatively increased metabolism in the cerebellum, brainstem, and temporo-occipital cortices, accompanied by relative metabolic decreases mainly in fronto-temporal and motor cortices. …”
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SURGICAL TECHNIQUE FOR COMPLEX SYNDACTYLY IN APERT SYNDROME: A SERIAL CASE by Williams Mesang, Agus Santoso Budi, Magda Rosalina Hutagalung

“…It is practically symmetrical causing significant dysfunction and infection if not treated properly. The goals in the treatment are the separation of independent digits without disturbing function and growth, the creation of a lined commissure, the provision of skin cover for the denuded nail edge and exposed bone, and to creation of aesthetically pleasing individual fingertips with proper nails, nail folds, and adequate pulp fullness. …”
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Inhibition of astrocyte signaling leads to sex-specific changes in microglia phenotypes in a diet-based model of cerebral small vessel disease by Jenna L. Gollihue, Khine Zin Aung, Colin B. Rogers, Leopoldine B. Galopin, Nicholas A. Wright, Pradoldej Sompol, Erica M. Weekman, Yuriko Katsumata, Josh M. Morganti, Christopher M. Norris

“…In contrast, microglial genes in females were less sensitive to diet and AAV treatments, though disease-like patterns were also observed in the HHcy condition. …”
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The crossroads of anxiety: distinct neurophysiological maps for different symptomatic groups by Gerez M, Suarez E, Serrano C, Castanedo L, Tello A

“…Hypothesis-related neurophysiological variables were combined into ten independent factors: 1) dysrhythmic patterns, 2) delta, 3) theta, 4) alpha, 5) beta (whole-head absolute power z-scores), 6) event-related potential (ERP) combined latency, 7) ERP combined amplitude (z-scores), 8) magnitude, 9) site, and 10) site of hyperactive networks. …”
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A Case of Status Epilepticus in a Patient Experiencing an Acute Attack of Hereditary Angioedema by Danielle Weinberg, Steven Gayda, Kyle Hultz, Hanan Atia, Brian Kohen, Eric Boccio

“…Hereditary angioedema is inherited in an autosomal dominant pattern and results in a quantitative deficiency (HAE type I) or dysfunction (HAE type II) of the C1-esterase inhibitor (C1-INH) protein. …”
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