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A spatial transcriptomic atlas of the host response to oropharyngeal candidiasis
Published 2025-08-01“…This approach provided a view of cellular interactions and immune dynamics, revealing intricate crosstalk between distinct immune cell populations. …”
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202
Hormonal and Transcriptomic Insights into Inflorescence Stalk Elongation in Oil Palm
Published 2025-06-01“…This study aimed to investigate the differences in stalk lengths between male and female inflorescences in Tenera oil palm and to elucidate the underlying hormonal and transcriptomic mechanisms. The stalk lengths from inflorescences associated with the fourth to eighteenth leaf positions of Tenera oil palm trees were measured, and hormone profiling and RNA sequencing (RNA-seq) were conducted in immature (F4 and M5) and mature (F14 and M13) stalks from an individual tree. …”
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203
Transcriptomic analysis of theca cells in a PCOS rat model: insights into follicular development
Published 2025-06-01“…PCR validation confirmed that Cyp17a1, Cyp11a1, S6k1, mTOR, Akt, Kit, and Tek were significantly upregulated in the PCOS group (P < 0.05). Conclusion Transcriptomic analysis identified key genes and pathways involved in follicular development dysregulation in PCOS rats, providing potential targets for further research.…”
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204
Unveiling Salt Tolerance Mechanisms in Plants: Integrating the KANMB Machine Learning Model With Metabolomic and Transcriptomic Analysis
Published 2025-06-01“…Using KANMB, 226 metabolic biomarkers significantly linked to salt stress responses, grounded in metabolomic and transcriptomic profiles are identified. These biomarkers correlate with metabolic pathways associated with salt tolerance, providing insight into the underlying biochemical mechanisms. …”
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205
CXCL14 drives age-related intervertebral disc degeneration via NF-κB pathway activation in a multiomic study
Published 2025-07-01“…We used transcriptomic and proteomic analyses to identify key regulatory genes associated with IDD. …”
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Degradation of lignocellulose by different bacterial and fungal co-cultures
Published 2024-01-01“…This work provided the proof of concept for technological feasibility, pertinence and usefulness of interdomain co-culture.…”
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208
Comparative transcriptomic and metabolomics analysis of ovary in Nilaparvata lugens after trehalase inhibition
Published 2025-02-01“…To investigate the mechanism by which trehalose affects the reproduction of N. lugens, we conducted a comparative transcriptomic and metabolomic analysis of the ovaries of N. lugens following injection with dsTREs and validamycin (a TRE inhibitor). …”
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209
Transcriptomic and metabolomic analyses for the mechanism underlying anthocyanin synthesis during the growth and development of purple eggplant (Solanum melongena L)
Published 2025-05-01“…Metabolomic profiling identified anthocyanin types, while transcriptomic data highlighted differentially expressed genes. …”
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210
Common antimicrobials disrupt early zebrafish development through immune-cardiac signaling
Published 2025-03-01“…All tested chemicals, except CX, cause significant teratogenic effects. Transcriptomic analysis reveals substantial disruptions in immune-related coagulation cascades and mitogen-activated protein kinase signaling pathways. …”
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211
Integrated analysis of methylomic and transcriptomic profiles in fetal mouse hypothalamus in response to maternal gestational exposure to arsenic
Published 2025-07-01“…Conclusion: This integrative analysis of methylomic and transcriptomic profiles in fetal mouse hypothalamus provides insights into the epigenetic and transcriptional responses to gestational arsenic exposure.…”
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212
The mechanism by which oriented polypropylene packaging alleviates postharvest ‘Black Spot’ in radish root (Raphanus sativus)
Published 2025-06-01“…Appearance and physiological parameters were assessed and transcriptomic and metabolomic analyses were conducted to identify the key molecular and biochemical factors contributing to the disorder and strategies for delaying its onset and development. …”
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213
The lamprey habenula provides an extreme example for the temporal regulation of asymmetric development
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Metabolomic and transcriptomic insights into the mechanisms of renal ischemia-reperfusion injury progression
Published 2024-12-01“…This study aims toinvestigate the potential mechanisms in the progression of IRI-AKI by integrating metabolomics and transcriptomics data, providing a reference for the subsequent identification of biomarkers and therapeutic targets. …”
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216
Multiparity induces persistent myocardial structural, functional and transcriptomic remodelling in mice
Published 2025-07-01“…Cardiac function was assessed by echocardiography together with transcriptomic analysis of the left ventricular myocardium. …”
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217
A Guide to Basic RNA Sequencing Data Processing and Transcriptomic Analysis
Published 2025-05-01“…RNA sequencing (RNA-Seq) has transformed transcriptomic research, enabling researchers to perform large-scale inspection of mRNA levels in living cells. …”
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218
A practical guide for single-cell transcriptome data analysis in neuroscience
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The GENDULF algorithm: mining transcriptomics to uncover modifier genes for monogenic diseases
Published 2020-12-01“…Taking advantage of the increasing availability of transcriptomic data, GENDULF is a novel addition to existing strategies for prediction of genetic disease modifiers, providing insights into disease pathogenesis and uncovering novel therapeutic targets.…”
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