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  1. 201

    A spatial transcriptomic atlas of the host response to oropharyngeal candidiasis by Sunna Nabeela, Hayden McSwiggin, Rubens Daniel Miserani Magalhaes, Eliciane Cevolani Mattos, Mohammad Mannan, John T. Dillon, Ashley Barbarino, Eman G. Youssef, Shakti Singh, Wei Yan, Ashraf S. Ibrahim, Heather R. Conti, Priya Uppuluri

    Published 2025-08-01
    “…This approach provided a view of cellular interactions and immune dynamics, revealing intricate crosstalk between distinct immune cell populations. …”
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    Article
  2. 202

    Hormonal and Transcriptomic Insights into Inflorescence Stalk Elongation in Oil Palm by Peng Shi, Yin Min Htwe, Dapeng Zhang, Zhiying Li, Qun Yu, Xiangman He, Jing Yang, Yong Wang

    Published 2025-06-01
    “…This study aimed to investigate the differences in stalk lengths between male and female inflorescences in Tenera oil palm and to elucidate the underlying hormonal and transcriptomic mechanisms. The stalk lengths from inflorescences associated with the fourth to eighteenth leaf positions of Tenera oil palm trees were measured, and hormone profiling and RNA sequencing (RNA-seq) were conducted in immature (F4 and M5) and mature (F14 and M13) stalks from an individual tree. …”
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  3. 203

    Transcriptomic analysis of theca cells in a PCOS rat model: insights into follicular development by Chen Yuanyuan, Sun Ningyu, Lu Lu, Zhang Wuwen, Li Kai, Li Yanting, He Junlan, Cheng Xiang, Zhou Jing, Yan Hua, Yin Ping

    Published 2025-06-01
    “…PCR validation confirmed that Cyp17a1, Cyp11a1, S6k1, mTOR, Akt, Kit, and Tek were significantly upregulated in the PCOS group (P < 0.05). Conclusion Transcriptomic analysis identified key genes and pathways involved in follicular development dysregulation in PCOS rats, providing potential targets for further research.…”
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    Article
  4. 204

    Unveiling Salt Tolerance Mechanisms in Plants: Integrating the KANMB Machine Learning Model With Metabolomic and Transcriptomic Analysis by Shoukun Chen, Hao Zhang, Shuqiang Gao, Kunhui He, Tingxi Yu, Shang Gao, Jiankang Wang, Huihui Li

    Published 2025-06-01
    “…Using KANMB, 226 metabolic biomarkers significantly linked to salt stress responses, grounded in metabolomic and transcriptomic profiles are identified. These biomarkers correlate with metabolic pathways associated with salt tolerance, providing insight into the underlying biochemical mechanisms. …”
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    Article
  5. 205

    CXCL14 drives age-related intervertebral disc degeneration via NF-κB pathway activation in a multiomic study by Tianle Zhou, Tonghui Zhang, Qiwang He, Zhiwen Zhang, Yong Huang, Zijun Chen, Wei Wang

    Published 2025-07-01
    “…We used transcriptomic and proteomic analyses to identify key regulatory genes associated with IDD. …”
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  6. 206
  7. 207

    Degradation of lignocellulose by different bacterial and fungal co-cultures by Julian Detain, Ludovic Besaury

    Published 2024-01-01
    “…This work provided the proof of concept for technological feasibility, pertinence and usefulness of interdomain co-culture.…”
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    Article
  8. 208

    Comparative transcriptomic and metabolomics analysis of ovary in Nilaparvata lugens after trehalase inhibition by Yongkang Liu, Fan Yang, Sijing Wan, Xianzhong Wang, Liwen Guan, Yan Li, Caidi Xu, Binghua Xie, Shigui Wang, Xiao-Ling Tan, Bin Tang

    Published 2025-02-01
    “…To investigate the mechanism by which trehalose affects the reproduction of N. lugens, we conducted a comparative transcriptomic and metabolomic analysis of the ovaries of N. lugens following injection with dsTREs and validamycin (a TRE inhibitor). …”
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    Article
  9. 209

    Transcriptomic and metabolomic analyses for the mechanism underlying anthocyanin synthesis during the growth and development of purple eggplant (Solanum melongena L) by Ting Yang, Wanping Lv, Runjie Zhuang, Shiyu Wang, Shuqi Fan, Yongxian Wen, Yongxian Wen

    Published 2025-05-01
    “…Metabolomic profiling identified anthocyanin types, while transcriptomic data highlighted differentially expressed genes. …”
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    Article
  10. 210

    Common antimicrobials disrupt early zebrafish development through immune-cardiac signaling by Yueyue Liu, Chen Wang, Zhiyou Fu, Yingchen Bai, Guomao Zheng, Fengchang Wu

    Published 2025-03-01
    “…All tested chemicals, except CX, cause significant teratogenic effects. Transcriptomic analysis reveals substantial disruptions in immune-related coagulation cascades and mitogen-activated protein kinase signaling pathways. …”
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    Article
  11. 211

    Integrated analysis of methylomic and transcriptomic profiles in fetal mouse hypothalamus in response to maternal gestational exposure to arsenic by Xuehua Li, Jinzhong Cui, Xinyu Zhang, Yue Wu, Jiajia Xu, Yonggan Zhao, Sajjad Hussain, Leishan Chen

    Published 2025-07-01
    “…Conclusion: This integrative analysis of methylomic and transcriptomic profiles in fetal mouse hypothalamus provides insights into the epigenetic and transcriptional responses to gestational arsenic exposure.…”
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  12. 212

    The mechanism by which oriented polypropylene packaging alleviates postharvest ‘Black Spot’ in radish root (Raphanus sativus) by Zixin Lin, Bihong Feng, Shibei Fang, Xi Pang, Huafeng Liang, Shuzhi Yuan, Xiaodi Xu, Jinhua Zuo, Xiaozhen Yue, Qing Wang

    Published 2025-06-01
    “…Appearance and physiological parameters were assessed and transcriptomic and metabolomic analyses were conducted to identify the key molecular and biochemical factors contributing to the disorder and strategies for delaying its onset and development. …”
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  15. 215

    Metabolomic and transcriptomic insights into the mechanisms of renal ischemia-reperfusion injury progression by Wanyi Li, Xiaoqing Liu, Honglin Li, Jiawei Zeng, Yan Chen, Bei Xu

    Published 2024-12-01
    “…This study aims toinvestigate the potential mechanisms in the progression of IRI-AKI by integrating metabolomics and transcriptomics data, providing a reference for the subsequent identification of biomarkers and therapeutic targets. …”
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  16. 216
  17. 217

    A Guide to Basic RNA Sequencing Data Processing and Transcriptomic Analysis by Rowayna Shouib, Gary Eitzen, Rineke Steenbergen

    Published 2025-05-01
    “…RNA sequencing (RNA-Seq) has transformed transcriptomic research, enabling researchers to perform large-scale inspection of mRNA levels in living cells. …”
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    The GENDULF algorithm: mining transcriptomics to uncover modifier genes for monogenic diseases by Noam Auslander, Daniel M Ramos, Ivette Zelaya, Hiren Karathia, Thomas O. Crawford, Alejandro A Schäffer, Charlotte J Sumner, Eytan Ruppin

    Published 2020-12-01
    “…Taking advantage of the increasing availability of transcriptomic data, GENDULF is a novel addition to existing strategies for prediction of genetic disease modifiers, providing insights into disease pathogenesis and uncovering novel therapeutic targets.…”
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    Article