Lymph node transcriptomic profiles suggest susceptibility to bleomycin-induced pulmonary toxicity in classic hodgkin lymphoma by Maja Dam Andersen, Marie Hairing Enemark, Kristina Lystlund Lauridsen, Stephen Jacques Hamilton-Dutoit, Jørn Starklint, Francesco d’Amore, Maja Ludvigsen, Peter Kamper

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Histological and Transcriptomic Insights into Rugose Surface Formation in Pepper (<i>Capsicum annuum</i> L.) Fruit by Yiqi Xie, Haizhou Zhang, Chengshuang Li, Qing Cheng, Liang Sun, Huolin Shen

“…To investigate its regulatory basis, histological, textural, and transcriptomic differences, contrasting genotypes were analyzed. …”
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Effects of Geraniol on Survival, Reproduction, Endophytes, and Transcriptome of Tea Green Leafhoppers (<i>Empoasca onukii</i>) by Junjie Tian, Hainuo Hong, Shiliang Mo, Shiqin Mo, Hongliang Shi, Juan Shi, Ying Zhou

“…These findings indicate that the strategic application of geraniol could be a promising approach to controlling tea green leafhopper populations. …”
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Transcriptomic Profiling Unveils EDN3+ Meningeal Fibroblasts as Key Players in Sturge‐Weber Syndrome Pathogenesis by Daosheng Ai, Tianyue Ming, Xiaoli Li, Shu Wang, Zhanying Bi, Jinyi Zuo, Zizhang Cheng, Weijin Sun, Mingguo Xie, Fengzhi Li, Xiongfei Wang, Xueling Qi, Guoming Luan, Woo‐ping Ge, Yuguang Guan

“…These findings not only expand the understanding of SWS but also open up promising avenues for therapeutic interventions.…”
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Machine learning of clinical phenotypes facilitates autism screening and identifies novel subgroups with distinct transcriptomic profiles by Wasana Yuwattana, Thanit Saeliw, Marlieke Lisanne van Erp, Chayanit Poolcharoen, Songphon Kanlayaprasit, Pon Trairatvorakul, Weerasak Chonchaiya, Valerie W. Hu, Tewarit Sarachana

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Biofilm matrix regulation by Candida glabrata Zap1 under acidic conditions: transcriptomic and proteomic analyses by Bruna Gonçalves, Diana Priscila Pires, Liliana Fernandes, Miguel Pacheco, Tiago Ferreira, Hugo Osório, Ana Raquel Soares, Mariana Henriques, Sónia Silva

“…In this study, we reveal that Zap1 regulates the matrix of C. glabrata acidic biofilms and analyzed the modulation of their transcriptome (by microarrays) and matrix proteome (by LC-MS/MS) by Zap1. …”
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Transcriptomic Differences Between Human Trabecular Meshwork Stem Cells and Trabecular Meshwork Cells Reveal Specific Biomarker Profiles by Rong Du, Ajay Kumar, Enzhi Yang, Jingxue Zhang, Ningli Wang, Yiqin Du

“…Trabecular meshwork stem cells (TMSCs) have emerged as promising candidates for TM regeneration toward glaucoma therapies, yet their molecular characteristics remain poorly defined. …”
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Deciphering salt-responsive NB-ARC genes in rice transcriptomic data: A bioinformatics approach with gene expression validation by Saputro Triono Bagus, Wardhani Fila Oxi, Sholihah Nur Fadlilatus, Ermavitalini Dini, Purnama Putut Rakhmad, Nurhidayati Tutik

“…LOC_Os11g39310 stands out as a promising marker essential for guiding selection in breeding programs aimed at cultivating salt-tolerant rice varieties.…”
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Rivaroxaban alleviates hepatic sinusoidal obstruction syndrome in mice by modulating the gut microbiota and inhibiting the PI3K/Akt signaling pathway by Wencheng Liu, Yanbin Cheng, Xue Han, Junlin Xia, Qingyu Wei, Bing Chang, Quansheng Li

“…Rivaroxaban may be a promising therapeutic option for treating HSOS.…”
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Transcriptomic profiling of cytomegalovirus infection in cardiac transplantation: proof-of-concept for a new strategy in tissue markers application by Ilaria Barison, Diego Perazzolo, Chiara Castellani, Alessia Giarraputo, Elisabetta Rossi, Elisabetta Rossi, Luca Vedovelli, Sonia Anna Minuzzo, Chiara Tessari, Nicola Pradegan, Giuseppe Toscano, Francesco Tona, Cristina Basso, Gino Gerosa, Susanna Mandruzzato, Susanna Mandruzzato, Davide Abate, Dario Gregori, Annalisa Angelini, Marny Fedrigo

“…This proof-of-concept study aims to assess the transcriptomic profile of CMV infection in cardiac transplanted patients as a new diagnostic approach to discriminate infection and Acute Cellular Rejection (ACR) on EMB specimens.MethodsWe performed a microarray-based messenger RNA (mRNA) and micro-RNA (miRNA) profiling. …”
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spliceJAC: transition genes and state‐specific gene regulation from single‐cell transcriptome data by Federico Bocci, Peijie Zhou, Qing Nie

“…Abstract Extracting dynamical information from single‐cell transcriptomics is a novel task with the promise to advance our understanding of cell state transition and interactions between genes. …”
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The Role of Genomics and Transcriptomics in Characterizing and Predicting Patient Response to Treatment in Triple Negative Breast Cancer (TNBC) by Franklin Eduardo Corea-Dilbert, Muhammad Zubair Afzal

“…These unique elements are the foundation of personalized medicine where genomics and transcriptomics play a critical role in increasing granularity in patients’ disease and treatment. …”
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Unraveling Ginsenoside Rg1’s osteoprotective pathways in zebrafish models of glucocorticoid induced osteoporosis via transcriptomics by Xinyu Fan, Ying Zhang, Xinyu Li, Junhui Ding, Jiaolong Huang, Kai Lian, Peng Duan, Chunhui Hu, Junchang Xu

“…Behavioural analysis revealed that Rg1 alleviated PN-induced hypoactivity, resulting in enhanced motion speed. Furthermore, transcriptome analysis identified 383 genes reversed by Rg1 treatment, with significant enrichment in skeletal system development. …”
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Artificial intelligence driven tumor risk stratification from single-cell transcriptomics using phenotype algebra by Namrata Bhattacharya, Anja Rockstroh, Sanket Suhas Deshpande, Sam Koshy Thomas, Anunay Yadav, Chitrita Goswami, Smriti Chawla, Pierre Solomon, Cynthia Fourgeux, Gaurav Ahuja, Brett Hollier, Himanshu Kumar, Antoine Roquilly, Jeremie Poschmann, Melanie Lehman, Colleen C Nelson, Debarka Sengupta

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Host blood transcriptomic biomarkers of tuberculosis disease in people living with HIV: a systematic review protocol by Mary Shelton, Humphrey Mulenga, Stanley Kimbung Mbandi, Simon C Mendelsohn, Mark Hatherill, Fatoumatta Darboe, Thomas J Scriba

“…Host tuberculosis transcriptomic biomarkers hold promise for diagnosing prevalent and predicting progression to incident tuberculosis and guiding further investigation, preventive therapy and follow-up. …”
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Cupric Doping Hollow Prussian Blue Nanoplatform for Enhanced Cholesterol Depletion: a Promising Strategy for Breast Cancer Therapy and Metastasis Inhibition by Shuangqian Yan, Panpan Xue, Ying Sun, Tingjie Bai, Sijie Shao, Xuemei Zeng

“…Abstract The dysregulated cholesterol metabolism in breast cancer cells drives malignancy, invasion, and metastasis, emphasizing the significance of reducing abnormal cholesterol accumulation for effective cancer treatment and metastasis inhibition. Despite its promise, cholesterol oxidase (ChOx) encounters challenge due to limited catalytic efficiency and susceptibility to harsh conditions. …”
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A multi-model approach identifies ALW-II-41-27 as a promising therapy for osteoarthritis-associated inflammation and endochondral ossification by Mauricio N. Ferrao Blanco, Raphaelle Lesage, Nicole Kops, Niamh Fahy, Fjodor T. Bekedam, Athina Chavli, Yvonne M. Bastiaansen-Jenniskens, Liesbet Geris, Mark G. Chambers, Andrew A. Pitsillides, Roberto Narcisi, Gerjo J.V.M. van Osch

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A promising drug repurposing approach for Alzheimer's treatment: Givinostat improves cognitive behavior and pathological features in APP/PS1 mice by Qi-Chao Gao, Ge-Liang Liu, Qi Wang, Sheng-Xiao Zhang, Zhi-Lin Ji, Zhao-Jun Wang, Mei-Na Wu, Qi Yu, Pei-Feng He

“…In summary, Givinostat offers a promising new strategy for AD treatment by targeting mitochondrial dysfunction.…”
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Transcriptomic analysis reveals potential crosstalk genes and immune relationship between triple-negative breast cancer and depression by Zhili Zhuo, Wenping Lu, Ling Zhang, Dongni Zhang, Yongjia Cui, Xiaoqing Wu, Heting Mei, Lei Chang, Qingya Song

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Spatial transcriptomics reveals macrophage domestication by epithelial cells promotes immunotherapy resistance in small cell lung cancer by Yu Sun, Minghui Zhang, Yanbin Zhao, Yubo Yan, Lei Wang, Xuhui Liu, Songsong Xia, Bingbing Wang, Xiaoxin Zhang, Yan Wang

“…Here, we applied spatial single-cell transcriptomics to investigate the spatial characteristics of SCLC and their associations with immunochemotherapy resistance. …”
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