Dexmedetomidine Protects the Brain: Exploring the α2AR/FAK Pathway in Post-Stroke Intestinal Barrier Repair by Xinting Zhou, Yan Yang, Zixuan Su, Zhonghui Luo

“…Statistical analyses included analysis of variance with Tukey’s post-hoc test. …”
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Isolation of a natural DNA virus of Drosophila melanogaster, and characterisation of host resistance and immune responses. by William H Palmer, Nathan C Medd, Philippa M Beard, Darren J Obbard

“…Using full transcriptome sequencing of infected males and females, we examine the transcriptional response of flies to Kallithea virus infection and describe differential regulation of virus-responsive genes. …”
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Genome-Wide Identification of Wheat Gene Resources Conferring Resistance to Stripe Rust by Qiaoyun Ma, Dong Yan, Binshuang Pang, Jianfang Bai, Weibing Yang, Jiangang Gao, Xianchao Chen, Qiling Hou, Honghong Zhang, Li Tian, Yahui Li, Jizeng Jia, Lei Zhang, Zhaobo Chen, Lifeng Gao, Xiangzheng Liao

“…Candidate genes within the QTL regions were inferred based on their transcription levels following the stripe rust inoculation. …”
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Genetic Associations of <i>ACOX2</i> Gene with Milk Yield and Composition Traits in Chinese Holstein Cows by Hui Cao, Zhe Wang, Lingna Xu, Bo Han, Dongxiao Sun

“…In addition, it was predicted that the T allele in the SNP rs109066086 created TFBSs for transcription factors NC2R2 and TFAP4, thereby potentially affecting <i>ACOX2</i> expression. …”
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Integrated functional genomic analysis identifies regulatory variants underlying a major QTL for disease resistance in European sea bass by Robert Mukiibi, Serena Ferraresso, Rafaella Franch, Luca Peruzza, Giulia Dalla Rovere, Massimiliano Babbucci, Daniela Bertotto, Anna Toffan, Francesco Pascoli, Sara Faggion, Carolina Peñaloza, Costas S. Tsigenopoulos, Ross D. Houston, Luca Bargelloni, Diego Robledo

“…Integration with chromatin accessibility and histone modification data pinpointed two SNPs in active regulatory regions of two of these genes (IFI27L2A and IFI27L2), and transcription factor binding site gains for the resistant alleles were predicted. …”
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Molecular epidemiologic characteristics and pretreatment drug resistance of HIV-1 in young and middle-aged first-diagnosed infections, 2019–2021 in Pudong New Area, Shanghai by Yan TANG, Jingjing LANG, Qiuli XU, Huiqin FU, Panpan CHEN, Lipeng HAO

“…The HIV-1 pol gene was amplified by reverse transcription-polymerase chain reaction (RT-PCR) for both pretreatment drug resistance genotyping and HIV-1 subtype determination, with subsequent analysis using the Stanford University HIV Drug Resistance Database for 302 successfully sequenced samples. …”
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Genetic Influence of the Brain on Muscle Structure: A Mendelian Randomization Study of Sarcopenia by Ting Lei, Zichao Jiang, Jiahao Wang, Jiangyu Nan, Long Hua, Zewu Zhu, Yihe Hu

“…Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway, protein–protein interaction (PPI), transcription factor interaction prediction and miRNA interaction prediction analysis were used to reveal potential signalling pathways and mechanisms. …”
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Non‐alcoholic fatty liver disease and heart failure: A comprehensive bioinformatics and Mendelian randomization analysis by Yayun Zhang, Lu Feng, Xin Guan, Zixiong Zhu, Yubin He, Xuewen Li

“…CIBERSORT analysis indicated associations between these hub genes and natural killer (NK) cells and macrophages. Transcription factor (TF) target prediction for CD38, CXCL10 and CCR1 highlighted related TFs. …”
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Deciphering the dynamic expression network of fiber elongation and the functional role of the GhTUB5 gene for fiber length in cotton based on an introgression population of upland... by Jianjiang Ma, Liupeng Yang, Yuanyue Dang, Kashif Shahzad, Jikun Song, Bing Jia, Li Wang, Juanjuan Feng, Nuohan Wang, Wenfeng Pei, Man Wu, Xuexian Zhang, Jinfa Zhang, Jianyong Wu, Jiwen Yu

“…Additionally, GhTUB5 was directly activated by GhHD-ZIP7, a homeobox-leucine zipper transcription factor, and its paralogous gene was previously reported to mediate fiber elongation. …”
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Perception of illusory vowels by Persian speakers in several consonant clusters of French loanwords by Saghar Javidpour, Aliyeh Kord Zafaranlu kambuziya, Mandana Nourbakhsh

“…In each trial, they heard a stimulus and were asked to identify the vowel between the two consonants, if any. A Persian transcription of the item was provided on screen. Participants were informed that the stimuli were non-words with no meaning, and they were instructed to choose the option that best matched how they would write down the word they heard, including the short vowels. …”
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How Do Arabidopsis Seedlings Sense and React to Increasing Ambient Temperatures? by Attila Fehér, Rasik Shiekh Bin Hamid, Zoltán Magyar

“…Thermomorphogenesis in the shoot and the root is overviewed separately, since the experiments indicate differences in key aspects of thermomorphogenesis in the two organs. This includes the variances in thermosensors and key transcription factors, as well as the predominance of cell elongation or cell division, respectively, even though auxin plays a key role in regulating this process in both organs. …”
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Distinctive features of IncRNA and mRNA between severe and mild patients with influenza a (H1N1) virus pneumonia by Dangsheng Xiao, Jinyou Li, Xuehui Zhao, Yongtao Li, Haifeng Lu, Jiezuan Yang

“…Objectives: The objectives of the study were to investigate the transcriptional variances in mRNA and lncRNA between severe and mild cases of H1N1 infection to discern potential markers contributing to the severity of the illness. …”
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Single‐microbe RNA sequencing uncovers unexplored specialized metabolic functions of keystone species in the human gut by Yifei Shen, Wenxin Qu, Mengdi Song, Tianyu Zhang, Chang Liu, Xiaofeng Shi, Xinxin Xu, Jingjing Jiang, Liguo Ding, Fangyu Mo, Zheying Mao, Mingzhu Huang, Ziye Xu, Jiaye Chen, Enhui Shen, Jian Ruan, Jiong Liu, Michael P. Timko, Yu Chen, Longjiang Fan, Shufa Zheng, Yongcheng Wang

“…Our results indicated that species‐function heterogeneity widely exists and plays important roles in the human gut microbiome, and through single‐microbe RNA sequencing, we have been able to capture the transcriptional activity variances and identify keystone species with specialized metabolic functions of possible biological and clinical importance.…”
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m6A-modified lncRNA GAS5 promotes M1-polarization of microglia in alcohol use disorder by Shuang Zhu, Peng Wang, Jian Hu

“…We assessed the expression levels of long noncoding RNA GAS5 (lncRNA GAS5) and microRNA-136–5p (miR-136–5p) in AUD tissue samples and cell lines using reverse transcription-quantitative polymerase chain reaction. …”
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Long noncoding nature brain-derived neurotrophic factor antisense is associated with poor prognosis and functional regulation in non–small cell lung caner by MingJing Shen, Zhonghua Xu, Kanqiu Jiang, Weihua Xu, Yongbin Chen, ZhongHeng Xu

“…Their endogenous brain-derived neurotrophic factor antisense expression levels were compared by quantitative reverse transcription polymerase chain reaction. Clinical relevance between endogenous brain-derived neurotrophic factor antisense expression level and patients’ clinicopathological variances or overall survival was analyzed. …”
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Multi-omics integration identifies NK cell-mediated cytotoxicity as a therapeutic target in systemic lupus erythematosus by Jingjing Zhang, Ling Ma, Hanyin Deng, Wenqian Yi, Alim Tohtihan, Xiaojun Tang, Xiudi Wu, Xuebing Feng

“…Significantly higher numbers of differentially accessible regions, transcripts, genes, mRNA, lncRNA, circRNA, and miRNA were observed in SLE patients compared to other cohorts, with these variances markedly reduced post-treatment. …”
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