Genome-wide association study of cassava starch paste properties. by Cristiano Silva Dos Santos, Massaine Bandeira Sousa, Ana Carla Brito, Luciana Alves de Oliveira, Carlos Wanderlei Piler Carvalho, Eder Jorge de Oliveira

“…The results indicated additive effects of the genetic control of Cold-PVisc, FinalVis, Hot-PVisc, and SetBack, especially on the large LD block on chromosome 18. One transcript encoding the glycosyl hydrolase family 35 enzymes on chromosome 17 and one encoding the mannose-p-dolichol utilization defect 1 protein on chromosome 18 were the most likely candidate genes for the regulation of CSPP. …”
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Assessment of the genetic diversity of cattle by marker genes of dairy productivity by Abramova M.V., Ilina A.V., Evdokimov E.G., Konovalov A.V., Mushtukova Yu.V.

“…Among the studied animals, the greatest genetic variance is accounted for by individual diversity - 82%. …”
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Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke. by Stephen R Williams, Qiong Yang, Fang Chen, Xuan Liu, Keith L Keene, Paul Jacques, Wei-Min Chen, Galit Weinstein, Fang-Chi Hsu, Alexa Beiser, Liewei Wang, Ebony Bookman, Kimberly F Doheny, Philip A Wolf, Michelle Zilka, Jacob Selhub, Sarah Nelson, Stephanie M Gogarten, Bradford B Worrall, Sudha Seshadri, Michèle M Sale, Genomics and Randomized Trials Network, Framingham Heart Study

“…Additionally, a genetic-score consisting of the five significant loci explains 13% of the variance of ΔPOST in FHS and 6% of the variance in VISP. …”
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%diag_test: a generic SAS macro for evaluating diagnostic accuracy measures for multiple diagnostic tests by Jacques K. Muthusi, Peter W. Young, Frankline O. Mboya, Samuel M. Mwalili

“…The SAS programmer can modify the source code to include other diagnostic measures and variance estimation methods. By automating analysis, the macro adds value by saving analysis time, reducing transcription errors, and producing publication-quality outputs.…”
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Circadian regulation of the transcriptome in a complex polyploid crop. by Hannah Rees, Rachel Rusholme-Pilcher, Paul Bailey, Joshua Colmer, Benjamen White, Connor Reynolds, Sabrina Jaye Ward, Benedict Coombes, Calum A Graham, Luíza Lane de Barros Dantas, Antony N Dodd, Anthony Hall

“…In wheat, period lengths of rhythmic transcripts are found to be longer and have a higher level of variance than in other plant species. …”
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Genome wide association analysis of a founder population identified TAF3 as a gene for MCHC in humans. by Giorgio Pistis, Shawntel U Okonkwo, Michela Traglia, Cinzia Sala, So-Youn Shin, Corrado Masciullo, Iwan Buetti, Roberto Massacane, Massimo Mangino, Swee-Lay Thein, Timothy D Spector, Santhi Ganesh, CHARGE Consortium Hematology Working, Nicola Pirastu, Paolo Gasparini, Nicole Soranzo, Clara Camaschella, Daniel Hart, Michael R Green, Daniela Toniolo

“…We show here that TAF3 is required for transcription of the SPTA1 gene, encoding alpha spectrin, one of the proteins that link the plasma membrane to the actin cytoskeleton. …”
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Effects of CTHRC1 on odontogenic differentiation and angiogenesis in human dental pulp stem cells by Jong-soon Kim, Bin-Na Lee, Hoon-Sang Chang, In-Nam Hwang, Won-Mann Oh, Yun-Chan Hwang

“…CTHRC1 doses of 5, 10, and 20 µg/mL were administered to hDPSCs. Reverse-transcription polymerase reaction was used to detect dentin sialophosphoprotein, dentin matrix protein 1, vascular endothelial growth factor, and fibroblast growth factor 2. …”
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ChromaFactor: Deconvolution of single-molecule chromatin organization with non-negative matrix factorization. by Laura M Gunsalus, Michael J Keiser, Katherine S Pollard

“…ChromaFactor provides the ability to identify trends accounting for the maximum variance in the dataset while simultaneously describing the contribution of individual molecules to each component. …”
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Varying effects of chlorination on microbial functional repertoire and gene expression in contrasting effluents by Mandy Lok Yi Tang, Stanley Chun Kwan Lau

“…Most of the genes and transcripts with significant changes in relative abundances were exclusive to their respective effluents. …”
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Transcriptome-wide assessment of human brain and lymphocyte senescence. by Mun-Gwan Hong, Amanda J Myers, Patrik K E Magnusson, Jonathan A Prince

“…<h4>Principal findings</h4>Among negatively correlated transcripts, an enrichment of mitochondrial genes was evident in both populations, providing a replication of previous studies indicating this as a common signature of aging. …”
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Valproate-vitamin E co-treatment preserved cortico-callosal white matter integrities in cypermethrin co-exposed pentylene tetrazole induced seizure by Aminu Imam, Oluwadamilola Eunice Ajibola, Aalimah Akinosho Akorede, Omamuyovwi Meashack Ijomone, Moyosore Salihu Ajao

“…Methods Histochemical and immunohistochemical analyses for hematoxylin and eosin (H&E), myelin basic protein (MBP), ionized calcium-binding adaptor molecule 1 (IBA1), glial fibrillary acidic protein (GFAP), and oligodendrocyte transcription factor 2 (OLIG-2) were conducted on cerebral white matter and corpus callosum tissues. …”
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Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression. by Michael S Cunnington, Mauro Santibanez Koref, Bongani M Mayosi, John Burn, Bernard Keavney

“…The proportion of expression variance attributable to cis-acting effects was 8% for CDKN2A, 5% for CDKN2B, and 20% for ANRIL. …”
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RBFOX1 and RBFOX3 mutations in rolandic epilepsy. by Dennis Lal, Eva M Reinthaler, Janine Altmüller, Mohammad R Toliat, Holger Thiele, Peter Nürnberg, Holger Lerche, Andreas Hahn, Rikke S Møller, Hiltrud Muhle, Thomas Sander, Fritz Zimprich, Bernd A Neubauer

“…The RBFOX1 protein and its homologues (RBFOX2 and RBFOX3) regulate alternative splicing of many neuronal transcripts involved in the homeostatic control of neuronal excitability. …”
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An in-depth characterization of the major psoriasis susceptibility locus identifies candidate susceptibility alleles within an HLA-C enhancer element. by Alex Clop, Anna Bertoni, Sarah L Spain, Michael A Simpson, Venu Pullabhatla, Raul Tonda, Christian Hundhausen, Paola Di Meglio, Pieter De Jong, Adrian C Hayday, Frank O Nestle, Jonathan N Barker, Robert J A Bell, Francesca Capon, Richard C Trembath

“…Although genome-wide association scans (GWAS) have identified 36 disease susceptibility regions, more than 50% of the genetic variance can be attributed to a single Major Histocompatibility Complex (MHC) locus, known as PSORS1. …”
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29 A Pilot Study of DataDay: Daily support for people with dementia by Hafsah Umar, Kristen Di, Stefano, Djellza Dani, Lashvanthy Shanmugunathan, Arlene Astell, Erica Dove, Joseph Ferenbok, Gilbert Sharpe

“…Quantitative data analysis will include repeated measures analysis of variance to compare pre- and post-intervention outcomes, such as medication use and ER visits. …”
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Sympatry and evolution: relationships between the endemic Myrcia guarujana and the widely distributed M. spectabilis by M. A. G. Magenta, L. F. Almeida, L. M. Rocha, C. E. A. Batista, R. H. G. Priolli

“…By AMOVA, the highest variance percentage found was 73.54% (P = 0.0079) between the species. …”
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A meta-analysis of gene expression signatures of blood pressure and hypertension. by Tianxiao Huan, Tõnu Esko, Marjolein J Peters, Luke C Pilling, Katharina Schramm, Claudia Schurmann, Brian H Chen, Chunyu Liu, Roby Joehanes, Andrew D Johnson, Chen Yao, Sai-Xia Ying, Paul Courchesne, Lili Milani, Nalini Raghavachari, Richard Wang, Poching Liu, Eva Reinmaa, Abbas Dehghan, Albert Hofman, André G Uitterlinden, Dena G Hernandez, Stefania Bandinelli, Andrew Singleton, David Melzer, Andres Metspalu, Maren Carstensen, Harald Grallert, Christian Herder, Thomas Meitinger, Annette Peters, Michael Roden, Melanie Waldenberger, Marcus Dörr, Stephan B Felix, Tanja Zeller, International Consortium for Blood Pressure GWAS (ICBP), Ramachandran Vasan, Christopher J O'Donnell, Peter J Munson, Xia Yang, Holger Prokisch, Uwe Völker, Joyce B J van Meurs, Luigi Ferrucci, Daniel Levy

“…The top BP signature genes in aggregate explain 5%-9% of inter-individual variance in BP. Of note, rs3184504 in SH2B3, which was also reported in GWAS to be associated with BP, was found to be a trans regulator of the expression of 6 of the transcripts we found to be associated with BP (FOS, MYADM, PP1R15A, TAGAP, S100A10, and FGBP2). …”
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Transcriptome Profiling Identifies Key Regulators of Tuber Skin Color in Potato by Boshu Li, Shuo Wang, Jun Hu, Liping Jin, Jianfei Xu

“…The color of tuber skin exhibits remarkable diversity in potato (<i>Solanum tuberosum</i> L.) and is intricately associated with variance in anthocyanin accumulation across different varieties. …”
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Effects of the cathepsin K inhibitor with mineral trioxide aggregate cements on osteoclastic activity by Hee-Sun Kim, Soojung Kim, Hyunjung Ko, Minju Song, Miri Kim

“…Data were analyzed by one-way analysis of variance and Tukey's post hoc test (p < 0.05).ResultsBiocompatibility results showed that there were no significant differences among any of the groups. …”
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Prophylactic Use of Troxerutin Can Delay the Development of Diabetic Cognitive Dysfunction and Improve the Expression of Nrf2 in the Hippocampus on STZ Diabetic Rats by Songyun Zhang, Lingling Yuan, Lihui Zhang, Caige Li, Jie Li

“…Nuclear factor E2-related factor 2 (Nrf2) is the core transcription factor of antioxidative stress. Early prevention and treatment of diabetic cognitive dysfunction can reduce the incidence of dementia and improve the quality of life of diabetic patients. …”
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