Trends and gender disparities in the burden of rheumatoid arthritis in Pakistan from 1990 to 2021 by Hong Cheng, Tao Li, Canxuan Li, Wei Su

“…Despite anticipated per-capita declines in RA incidence, prevalence, mortality, and DALYs by 2036, demographic shifts will likely sustain a substantial absolute burden. These findings emphasize the necessity of precise public health measures to advance early diagnosis, optimize disease management, and reinforce prevention—particularly in rapidly developing areas and among high-risk groups such as women and the elderly.…”
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Kinetic Pattern Recognition in Home-Based Knee Rehabilitation Using Machine Learning Clustering Methods on the Slider Digital Physiotherapy Device: Prospective Observational Study by Clement Twumasi, Mikail Aktas, Nicholas Santoni

“…Gender was the strongest determinant for the left knee, with male participants significantly likely to belong to cluster 3 (OR 3.52, 95% CI 2.91-4.27; P<.001). …”
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Using Machine Learning Approaches on Dynamic Patient-Reported Outcomes to Cluster Cancer Treatment-Related Symptoms by Nora Asper, Hans Friedrich Witschel, Louise von Stockar, Emanuele Laurenzi, Hans Christian Kolberg, Marcus Vetter, Sven Roth, Gerd Kullak-Ublick, Andreas Trojan

“…The machine learning model was not able to recognize any of the patients with prostate and blood–lymph cancer, likely as these cancer types were barely represented in the dataset. …”
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Water quality improvements and ecological inertia: a basin-wide assessment of ecosystem recovery in the Yangtze River system (2005–2022) by Xingchen Zhao, Yunlin Zhang, Haoran Tang, Qingji Zhang, Chixiao Cui, Boqiang Qin

“…Here, we synthesize an 18‑year (2005–2022) multisource dataset—including monthly measurements of 24 water‑quality parameters at 1,014 river cross‑sections, chlorophyll‑a (Chla) concentrations, remote‑sensing of macrophyte cover, benthic invertebrate surveys across 99 lakes, and upper‑river fish‑catch data (1998–2022)—to assess recovery trajectories across the basin. This integrated analysis revealed that rivers exhibited rapid and uniform improvements in total nitrogen (TN), total phosphorus (TP), ammonia‑N (NH3‑N), and permanganate index of chemical oxygen demand (CODMn), with 95.4 % of sites achieving China’s Grade I–III water quality by 2022 (Grade I indicating optimal water quality), reflecting successful pollution control measures. …”
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Collagenase injection versus limited fasciectomy surgery to treat Dupuytren’s contracture in adult patients in the UK: DISC, a non-inferiority RCT and economic evaluation by Joseph Dias, Puvan Tharmanathan, Catherine Arundel, Charlie Welch, Qi Wu, Paul Leighton, Maria Armaou, Belen Corbacho, Nick Johnson, Sophie James, John Cooke, Christopher Bainbridge, Michael Craigen, David Warwick, Samantha Brady, Lydia Flett, Judy Jones, Catherine Knowlson, Michelle Watson, Ada Keding, Catherine Hewitt, David Torgerson

“…Recovery of hand function was quicker for participants who received the injection; however, they were more likely to need further treatment (i.e. further care and/or re-intervention). …”
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