Development and mechanism study of functional fermentation media for reducing alkaloid content in cigar tobacco leaves by Wanrong Hu, Li Liu, Jiabao Zhang, Quanwei Zhou, Zhongrong Jiang, Yun Jia, Qianying Zhang, Dongliang Li

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Analysis of effective factors on integrated local management in peripheral rural settlements of Tehran metropolitan by Masoumeh Ghorbani, Alireza Darban Astaneh, Mohammad Reza Rezvani, Mojtaba Ghadiri Masoum

“…The main tool for collecting data is a questionnaire and a total of 350 questionnaires have been distributed and completed. …”
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Functional insights from recombinant production of bacterial proteases in Saccharomyces cerevisiae by Tova Lindh, Mattias Collin, Rolf Lood, Magnus Carlquist

“…Conclusions S. cerevisiae was found to be an efficient expression host for the bacterial protease IdeS. …”
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Rhizobacteria consortium improves growth, yield, and phytochemicals in Robusta coffee (Coffea canephora L.) by Ni Luh Suriani, Mohammed Al-zharani, Fahd A. Nasr, Lina M. Alneghery, Dewa Ngurah Suprapta, I. Nyoman Suarsana, Ni Made Delly Resiani, Hesham Ali El Enshasy, Hesham Ali El Enshasy, Riyaz Sayyed, Jayanthi Barasarathi, Ting Seng Ho, Yulmira Yanti

“…The F3 treatment proved to be the most efficient in enhancing growth, antioxidant activity, alkaloid content, tannin levels, caffeine concentration, and coffee production, whereas the F2 treatment resulted in the highest flavonoid content. …”
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Deforestation Risk Zoning Using Analytical Hierarchy Process by Hiva Mahmoudi, Mahtab Pir Bavaghar, Parviz Fatehi

“…According to the zoning map, about 60% of the total area is in a high and very high-risk zone. …”
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Enhancing sustainable solid waste management through separate source collection by O. Arabiyat, J.T. Al-Bakri, F. Kölsch, S. Al-Omari, H. Aladwan

“…A significant amount of municipal solid waste (60 percent) has an organic composition, while recyclable waste constitutes about 12.5 percent of the total municipal solid waste. The study was a success, with a consistent increase in recyclable waste collection at 59 percent average purity and a 30 percent decrease in total yearly waste collection costs. …”
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Genotypic Variation in Drought-Season Stress Responses Among Traditional Fig (<i>Ficus carica</i> L.) Varieties from Mediterranean Transition Zones of Northern Morocco by Mohammed Elmeknassia, Abdelali Boussakouran, Rachid Boulfia, Yahia Rharrabti

“…Among locations, Chefchaouen showed the highest protein, TSS, H₂O₂, and MDA levels, reflecting active stress tolerance mechanisms. These variations were confirmed by principal component analysis, which revealed a clear separation between photosynthetically efficient varieties (Nabout and Ounq Hmam) and stress-tolerant varieties (Ghouddane and Fassi). …”
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Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study. by Robert Molokie, Donald Lavelle, Michel Gowhari, Michael Pacini, Lani Krauz, Johara Hassan, Vinzon Ibanez, Maria A Ruiz, Kwok Peng Ng, Philip Woost, Tomas Radivoyevitch, Daisy Pacelli, Sherry Fada, Matthew Rump, Matthew Hsieh, John F Tisdale, James Jacobberger, Mitch Phelps, James Douglas Engel, Santhosh Saraf, Lewis L Hsu, Victor Gordeuk, Joseph DeSimone, Yogen Saunthararajah

“…This dose decreased DNMT1 protein in peripheral blood mononuclear cells by >75% and repetitive element CpG methylation by approximately 10%, and increased HbF by 4%-9% (P < 0.001), doubling fetal hemoglobin-enriched red blood cells (F-cells) up to approximately 80% of total RBCs. Total hemoglobin increased by 1.2-1.9 g/dL (P = 0.01) as reticulocytes simultaneously decreased; that is, better quality and efficiency of HbF-enriched erythropoiesis elevated hemoglobin using fewer reticulocytes. …”
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Combining Carboxylic-Acid-Based Deep Eutectic Solvents and High Temperatures Enhances Phenolic Acid Extraction from Grape Pomace by Francesca Lorenzo, Marialaura Frisina, Sonia Bonacci, Monica Nardi, Manuela Oliverio, Antonio Procopio

“…Phenolic acids are contained in grape pomace, mostly in a conjugate form, and can be a natural source of building blocks if they are efficiently hydrolyzed and extracted from the natural matrix. …”
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Intercellular interactions and progression of hormonal resistance of breast cancer cells by S. E. Semina, D. V. Bagrov, M. A. Krasil’nikov

“…Hormonal independence may be accompanied with the loss of the receptors, as well as with the another mechanisms including ligand-independent receptor activation, disbalance between receptor activators and repressors, stimulation of hormone-independent pathways. …”
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Physiological and molecular mechanisms of exogenous salicylic acid in enhancing salt tolerance in tobacco seedlings by regulating antioxidant defence system and gene expression by Xiliang Song, Jian Chen, Can Xu, Xianjie Cai, Wenjing Song, Aixia Chang, Yu Zhang, Chenggang Luo

“…The plant hormone salicylic acid (SA) has notable potential in mitigating salt toxicity, yet its mechanism in enhancing the salinity tolerance of tobacco plants is not well explored.MethodsThis study aimed to assess the potential benefits of exogenous SA application (1.0 mM) on tobacco seedlings subjected to saline soil conditions.ResultsThe foliar spray of SA partially mitigated these salt-induced effects, as evidenced by a reduction of malondialdehyde content, and improvements of leaf K+/Na+ ratios, pigment biosynthesis, and electron transport efficiency under NaCl stress. Additionally, SA increased the contents of total phenolic compound and soluble protein by 16.2% and 28.7% to alleviate NaCl-induced oxidative damage. …”
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Chicken liver meal as an effective fishmeal replacement for Litopenaeus vannamei diets: A comprehensive evaluation of growth, non-specific immunity and gut health by Huaxing Lin, Wanting Huang, Xuehe Li, Jiahua Wu, Beiping Tan, Shuyan Chi, Qihui Yang

“…Whole body crude protein (CP) content was significantly higher in the C20 group (P < 0.05). Total antioxidant capacity (T-AOC), catalase (CAT) and superoxide dismutase (SOD) activities were significantly (P < 0.05) higher in C20, C40, C60 and C80 groups. …”
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Determining the Bioavailability Percentage of Bone Ash Phosphorus Compared to Monocalcium Phosphate and Its Effect on Performance, Bone Quality and Phosphorus Digestibility in Broi... by Mohammad Sedghi, Zahra Sarrami, Raziye Ghasemi, Mahdi Zanghae

“…Phosphorus plays a vital role in muscle function, enzyme activity, lipid metabolism, bone mineralization, maintaining osmotic and acid-base balance, energy metabolism, amino acid metabolism, and protein synthesis. …”
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Dihydroartemisinin-sodium taurocholate-PLGA nanoparticles: a novel therapeutic approach against cystic echinococcosis by Aierpati Moheteer, Aierpati Moheteer, Jiang Zhu, Jiang Zhu, Dongming Pang, Dongming Pang, Xue Rao, Xue Rao, Nijiati Aini, Nijiati Aini, Kalibixiati Aimulajiang, Zhenping Zhang, Zhenping Zhang, Saifuding Abula, Saifuding Abula, Adelijiang Wusiman, Adelijiang Wusiman

“…IntroductionDihydroartemisinin (DHA) demonstrates potent anti-echinococcal activity. However, its clinical application is constrained by non-specific biodistribution and low bioavailability. …”
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Optimizing polyphenol extraction and UPLC-MS/MS analysis from red clover (Trifolium pratense L.) species using response surface methodology by Emily P. Verhulst, Carlos Álvarez, Nigel P. Brunton, Dilip K. Rai

“…Central composite design software was used to conduct Response Surface Methodology (RSM) modelling and optimize the polyphenol yield from the red clover. Total phenolic content, antioxidant activity and ultra-performance liquid chromatography mass-spectrometry (UPLC-MS/MS) analysis were used to quantify polyphenols. …”
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Optimization of antioxidant extraction from agro-industrial wastes using ultrasound &amp; response surface methodology by Dunja Malenica, Marko Kass, Rajeev Bhat

“…This study assessed the total polyphenol content (TPC) and antioxidant activity (DPPH• and ABTS•+) of under-researched materials : hempseed hulls (HH), oat bran (OB), sea buckthorn pomace with (SBPS) and without seeds (SBPW), and sea buckthorn leaves (SBL) using conventional solvent extraction (CSE) and ultrasound-assisted extraction (UAE). …”
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Enhanced Ciprofloxacin Ozonation Degradation by an Aqueous Zn-Cu-Ni Composite Silicate: Degradation Performance and Surface Mechanism by Yue Liu, Rong Guo, Jie Li, Yizhen Cheng, Congmin Wang, Weiqiang Wang, Huifan Zheng

“…The chemical coprecipitation method was used in this study to prepare the Zn-Cu-Ni composite silicate, serving as a heterogeneous ozonation catalyst. The catalytic activity was then evaluated by degrading ciprofloxacin (CIP). …”
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Study on Mechanical and Microscopic Properties of Fly Ash Cement-Based Materials in High Geothermal Environment by Yehong Hu, Wen Xie, Feng Zou, Jialei Yang, Tian Xi, Ruijun Li, Xin Wang, Xuefeng Xu

“…Last, under a hot and humid environment of high ground temperature, fly ash saturation in cementing material should range from 20% to 30% in mass of total binder, which makes for long-term performance of cement-based materials.…”
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The Role of Innovative Entrepreneurship in the Economic Development of EU Member Countries by Rodica Crudu

“…The key findings of the paper show that innovative entrepreneurs (being measured by the Total Early-stage Entrepreneurial Activity (TEA) innovation level) are more present in countries with higher development levels and higher incomes, being motivated by the improvement opportunity they see in becoming entrepreneurs. …”
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A systematic review on sleep stage classification and sleep disorder detection using artificial intelligence by Tayab Uddin Wara, Ababil Hossain Fahad, Adri Shankar Das, Md Mehedi Hasan Shawon

“…Sleep is vital for our physical and mental health, and sound sleep can help us to focus on daily activities. Therefore, a sleep study that includes sleep patterns and disorders is crucial to enhancing our knowledge about individual health status. …”
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