Extraction of natural antioxidants from Moroccan saffron (Crocus sativus L.) using ultrasound-assisted extraction: An optimization approach with box-behnken design by Chaimae Slimani, Mouhcine Fadil, Chaimae Rais, Laila El-hanafi, Meryem Benjelloun, Hyeong-Moo Shin, John P. Giesy, Abderrahim Lazraq, Mahmoud M.A. Abulmeaty, Khalid M. Almutairi, Mourad A.M. Aboul-Soud

“…This study developed an ultrasound-assisted extraction technique to improve the efficiency of phenolic compound extraction and assess the antioxidant activity of saffron. …”
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Effects of cinnamon, rosemary and oregano on growth performance, blood biochemistry, liver enzyme activities, excreta microbiota and ileal morphology of Campylobacter jejuni‐challe... by Zahra Alimohammadi, Hassan Shirzadi, Kamran Taherpour, Enayat Rahmatnejad, Ali Khatibjoo

“…Feed intake, body weight gain (BWG), feed conversion ratio (FCR), energy efficiency ratio (EER) and protein efficiency ratio (PER) were assessed during the rearing period (0–42 days). …”
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Optimization of extraction in supercritical fluids in obtaining Pouteria lucuma seed oil by response surface methodology and artificial neuronal network coupled with a genetic algo... by Alex Chauca-Cerrutti, Marianela Inga, José Luis Pasquel-Reátegui, Indira Betalleluz-Pallardel, Gustavo Puma-Isuiza

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Activity-Based CO₂ Emission Analysis of Rail Container Transport: Lat Krabang Inland Container Depot–Laemchabang Port Corridor Route by Nilubon Wirotthitiyawong, Thanapong Champahom, Siwadol Pholwatchana

“…Fuel consumption testing revealed a power relationship between train weight and fuel consumption (<i>y</i> = 0.1121<i>x</i>^0.5147, <i>R</i>² = 0.97), indicating improving efficiency with increased loading. Terminal operations contribute significantly to rail transport’s emission profile, accounting for 36% of total emissions. …”
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Polyol-based ultrasound-assisted extraction: Unlocking the anti-tyrosinase and anti-melanogenesis potential of Vitex trifolia Linn. Leaves by Nuntawat Khat-Udomkiri, Panthipa Petsringoen

“…The selected UAE conditions: 50 % (w/v) propylene glycol, 1:50 solid-to-solvent ratio, ultrasonic power level 9-, and 60-min extraction, yielded a total phenolic content of 11.15 ± 0.25 mg GAE/g sample, DPPH scavenging activity of 9.08 ± 0.42 mg TE/g sample, and tyrosinase inhibition of 1.08 ± 0.09 mg KAE/g sample. …”
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Optimising ultrasound-assisted extraction conditions for maximising phenolic, flavonoid content and antioxidant activity in hog plum peel and seed: A response surface methodology a... by A.S.M. Sayem, Tanvir Ahmed, Md Usuf Khan Mithun, Mamunur Rashid, Md Rahmatuzzaman Rana

“…This study optimised ultrasound-assisted extraction (UAE) temperature, time, and ethanol concentration to investigate total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activity (DPPH free radical scavenging activity assay) from hog plum peel and seed. …”
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Optimizing Effects of Organic Farming and Moderately Low Nitrogen Levels on Soil Carbon and Nitrogen Pools by Guanghua Wang, Yu Yang, Yuqi Chen, Shilong Yu, Xiaomin Huang, Min Jiang, Zujian Zhang, Lifen Huang

“…However, the existing research on optimizing nitrogen use efficiency and soil carbon sequestration in organic systems remains limited. …”
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Poor sleep quality is common and independently associated with disease activity and poor quality of life in inflammatory bowel disease: a long-term follow-up study by Thanaboon Chaemsupaphan, Chawanont Pimolsri, Nichcha Subdee, Phutthaphorn Phaophu, Marianee Salaemae, Parinya Permpim, Lakkana Thongchot, Kamonnet Wannasewok, Wattanachai Chotinaiwattarakul, Julajak Limsrivilai

“…Longitudinal correlation was analyzed. Results: A total of 98 participants were enrolled, consisting of 68 remission, 21 mild, and 9 moderate-to-severe disease activities. …”
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Effect of High Pressure Sodium and Light-Emitting Diode Lamps’ Supplementary Lighting and Diffusion Glass on Growth, Yield, and Fruit Quality of Pink Tomato by Katarzyna Kowalczyk, Małgorzata Mirgos, Anna Geszprych, Jarosław Przybył, Marzena Sujkowska-Rybkowska, Wojciech Borucki, Stanisław Kalisz, Jerzy Jonczak, Anna Sobczak-Samburska, Małgorzata Kunka, Janina Gajc-Wolska

“…In this study, for first time, the efficiency of the yield and fruit quality of the pink tomato cultivar ‘Tomimaru Muchoo’ was studied in hydroponic cultivation with top and interlighting with LEDs (light-emitting diodes) and diffusion glass (<i>DGlass</i>) to cover the glasshouse roof (LED+LED+<i>DGlass</i>). …”
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One step preparation of papyrus culm derived activated biochar using partial air oxidation and its use as a filter for water treatment in aquaponics culture by Sumrit Mopoung, Suthasinee Pantho

“…Utilizing the derived activated biochar prepared with carbonization at 600 °C for aquaponics culture has shown that the values of total NH3, NO2–, NO3–, PO43-, and turbidity decreased, while the DO content increased in the water of the aquaponics culture with efficiency percentage values of 33.33–35.90 %, 4.93–13.43 %, 9.15–12.90 %, 34.97–43.04 %, 10.23–23.90 %, and 16.86–23.90 %, respectively, throughout the four weeks of the experiment. …”
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Novel inhibitors of dengue virus methyltransferase: discovery by in vitro-driven virtual screening of fucoidan analogues, its synthesis, characterization, and potential in-vitro an... by Kothai Ramalingam, Arul Balasubramanian, Saravanan Muniappan, Kalirajan Rajagopal, Nagappan Andiappan

“…These molecules may produce efficient anti-dengue activity against DENV2. Compound FUC-4 was subjected to MD simulation at 100 ns and it showed the highest binding affinity with methyl transferase. …”
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Recombinant Expression and Functional Analysis of the AEJ-CHAP Domain from Staphylococcus aureus Endolysin by Jingjing DENG, Hui YIN, Waner LI, Zhanpeng LI, Jian LI, Hongzhou LÜ

“…Notably, CHAP has a smaller molecular weight than CHAP-Amidase, contributing to higher expression efficiency. A considerable effect on lytic activity was exerted by metal ions, with CHAP's activity being greatly increased by Mg2+ and Ca2+, whereas inhibitory effects were shown by Mn2+, Zn2+, and Cu2+, with its activity being almost totally suppressed by Zn2+ and Cu2+. …”
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Life Cycle Assessment and Activity-Based Costing for Low-Cost Aluminum die manufacturing: A comparative study of machining process, conventional and rapid investment casting by Samina Bibi, Muhammad Sajid, Wasim Ahmad, Muhammad Asad Ali, Mirza Jahanzaib, Salman Hussain

“…ABC results indicate that CIC incurs the highest total cost (PKR 422,600.35), with labor alone contributing 81.39 %. …”
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Effect of Culture Density on Growth, Digestive Enzymes, and Intestinal Flora of Net-Cage Culture of Sea Cucumber (Apostichopus japonicus) Under Feeding Mode by Yiming SONG, Jianlong GE, Meijie LIAO, Bin LI, Xiaojun RONG, Yingeng WANG, Jinjin WANG, Limei CHEN

“…Digestive enzyme (Trypsin, Amylase, and Lipase) activities were determined spectrophotometrically using enzyme activity assay kits (Nanjing Jiancheng Bioengineering Institute, China) following the manufacturer's instructions. …”
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Changes of Peripheral T Cells in Systemic Lupus Erythematosus Patients by Juanfeng Lao, Rongjun Huang, Rongcai Wu, Yulin Yuan

“…This study aimed to find biomarkers to assess lymphocyte‐mediated immune response in SLE patients. Methods A total of 81 SLE patients (non‐active: n = 35, active: n = 46) and 70 healthy donors were recruited in the study. …”
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Seasonal alternation of soil phosphorus saturation in rice-wheat rotation systems under multiple fertilization strategies by Gang Wu, Lulu Wei, Wenjing Shang, Jiabao Wang, Manman Yuan, Qing Chen, Yixiang Sun, Shuai Zhang

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Safety of an inactivated enterovirus 71 vaccine administered concurrently with other vaccines among infants aged 6–11 months: An observational study using active surveillance by Linlin Wu, Yu Zhang, Jiechen Liu, Zhuoying Huang, Huiyong Shao, Xiaoying Ma, Xiaodong Sun

“…This study aimed to evaluate the safety of the enterovirus 71 (EV71) vaccine administered alone or concurrently with other vaccines in infants 6–11 months. A total of 3,769 EV71 vaccine doses were administered to children in the active surveillance area, of which 1,909 were administered concurrently with other vaccines and 1,860 doses were administered alone. …”
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LONG-TERM SAFETY AND EFFICACY OF TOCILIZUMAB IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS OF MODERATE OR HIGH ACTIVITY (RESULTS OF PHASE III MULTICENTER EXTENSION CLINICAL STUDY ML2... by E. L. Nasonov, M. L. Stanislav, V. I. Mazurov, T. M. Chernykh, V. N. Sorotskaya, T. S. Salnikova, R. S. Saikovsky, O. V. Reshet’ko, T. A. Popova, E. I. Shmidt, V. P. Tyurin, N. P. Shilkina, I. N. Bokarev, M. Z. Kanevskaya, S. S. Yakushin

“…Objective: to assess the long-term safety and efficiency of tocilizumab (TCZ) therapy in patients with early rheumatoid arthritis (RA) of moderate and high activity, who have completed the basic WA19926 study, as well as the rate of sustained drug-free remission.Subjects and methods. …”
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Impact of stocking density on oxidative stress, digestive enzyme activity, ATPase function, and transcriptomic changes in juvenile Crimson snapper (Lutjanus erythropterus) during l... by Jiaqi Su, Yu Guo, Jiayang Li, Karsoon Tan, Chuanxin Qin

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Dietary creatine improves the growth performance, antioxidant capacity and energy metabolism of common carp (Cyprinus carpio) by activating glucose metabolism and the Nrf2-Keap1 pa... by Meiqi Xing, Xinchi Shang, Longwu Geng, Haijun Wei, Xinghua Che, Xiaodan Shi, Zhengwei Li, Hailong He, Wei Xu

“…In addition, the addition of 0.5 g/kg creatine activated the Nrf2-Keap1 pathway; significantly increased the activities of catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GSH-PX); increased the total antioxidant capacity (T-AOC); and decreased the content of malondialdehyde (MDA) (P < 0.05), which improved antioxidant capacity. …”
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