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    Identify the potential target of efferocytosis in knee osteoarthritis synovial tissue: a bioinformatics and machine learning-based study by Shangbo Niu, Shangbo Niu, Shangbo Niu, Mengmeng Li, Mengmeng Li, Mengmeng Li, Jinling Wang, Jinling Wang, Jinling Wang, Peirui Zhong, Peirui Zhong, Peirui Zhong, Xing Wen, Xing Wen, Xing Wen, Fujin Huang, Fujin Huang, Fujin Huang, Linwei Yin, Linwei Yin, Linwei Yin, Yang Liao, Yang Liao, Yang Liao, Jun Zhou, Jun Zhou, Jun Zhou

    Published 2025-02-01
    “…A critical mechanism in the pathogenesis of KOA is impaired efferocytosis in synovial tissue. The present study aimed to identify and validate key efferocytosis-related genes (EFRGs) in KOA synovial tissue by using comprehensive bioinformatics and machine learning approaches.MethodsWe integrated three datasets (GSE55235, GSE55457, and GSE12021) from the Gene Expression Omnibus database to screen differentially expressed genes (DEGs) associated with efferocytosis and performed weighted gene co-expression network analysis. …”
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    Histopathological Image Analysis Using Machine Learning to Evaluate Cisplatin and Exosome Effects on Ovarian Tissue in Cancer Patients by Tuğba Şentürk, Fatma Latifoğlu, Çiğdem Gülüzar Altıntop, Arzu Yay, Zeynep Burçin Gönen, Gözde Özge Önder, Özge Cengiz Mat, Yusuf Özkul

    Published 2025-02-01
    “…This study aims to evaluate the reparative effects of cisplatin and exosome treatments on ovarian tissue damage through the analysis of histopathological images and machine learning (ML)-based classification techniques. …”
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    Robotic Integration of Massage and Real-Time Tissue Assessment: A Technological Framework by Yizhong Zhang, Hui Zhang, Chen Qiu, Shaosong Xie, Min Tang, Yue-Guang Fan

    Published 2025-01-01
    “…Compared with traditional soft tissue assessment devices, the massage robot equipped with a stiffness assessment system that leverages integrated sensors, enables real-time monitoring of soft tissue conditions during massage, thus integrates detection and treatment seamlessly. …”
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    Deep Learning Technique for Automatic Segmentation of Proximal Hip Musculoskeletal Tissues From CT Scan Images: A MrOS Study by Mahdi Imani, Jared Buratto, Thang Dao, Erik Meijering, Sara Vogrin, Timothy C. Y. Kwok, Eric S. Orwoll, Peggy M. Cawthon, Gustavo Duque

    Published 2025-04-01
    “…This study aims to develop a deep learning technique for segmentation and quantification of musculoskeletal tissues in CT scans of proximal hip. …”
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    Different effects of scopolamine on learning, memory, and nitric oxide metabolite levels in hippocampal tissues of ovariectomized and Sham-operated rats by Hamid Azizi-Malekabadi, Mahmoud Hosseini, Mohammad Soukhtanloo, Reihaneh Sadeghian, Masoud Fereidoni, Fatimeh Khodabandehloo

    Published 2012-06-01
    “…Different effects of scopolamine on learning, memory, and nitric oxide (NO) metabolites in hippocampal tissues of ovariectomized (OVX) and sham-operated rats were investigated. …”
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    Exploring novel molecular mechanisms underlying recurrent pregnancy loss in decidual tissues by Hui Ding, Yajie Gao, Yuan Gao, Yulu Chen, Ruimin Liu, Caili Wang, Yuqing Gao

    Published 2025-07-01
    “…Machine learning (LASSO, SVM-RFE, RF) identified optimal feature genes, which were validated via real-time quantitative polymerase chain reaction (RT-qPCR) and immunohistochemistry (IHC). …”
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    An in vivo systemic massively parallel platform for deciphering animal tissue-specific regulatory function by Ashley R. Brown, Ashley R. Brown, Grant A. Fox, Grant A. Fox, Irene M. Kaplow, Irene M. Kaplow, Irene M. Kaplow, Alyssa J. Lawler, Alyssa J. Lawler, BaDoi N. Phan, BaDoi N. Phan, BaDoi N. Phan, Lahari Gadey, Lahari Gadey, Morgan E. Wirthlin, Morgan E. Wirthlin, Easwaran Ramamurthy, Easwaran Ramamurthy, Gemma E. May, Ziheng Chen, Qiao Su, Qiao Su, C. Joel McManus, Robert van de Weerd, Robert van de Weerd, Andreas R. Pfenning, Andreas R. Pfenning, Andreas R. Pfenning

    Published 2025-04-01
    “…Here, we introduce a systemic MPRA (sysMPRA) to address these challenges through systemic intravenous AAV viral delivery.Results: We demonstrate successful transduction of the MPRA library into diverse mouse tissues, efficiently identifying tissue specificity in candidate enhancers and aligning well with predictions from machine learning models. …”
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