Numerical simulation of a steel weld joint and fracture mechanics study of a Compact Tension Specimen for zones of weld joint by Ahmed Bensari, El Bahri Ould Chikh, Benattou Bouchouicha, Malika Tirenifi

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Ice sheet model simulations reveal that polythermal ice conditions existed across the northeastern USA during the Last Glacial Maximum by J. K. Cuzzone, A. Barth, K. Barker, M. Morlighem

“…<p>Geologic archives of the Laurentide Ice Sheet (LIS) provide abundant constraints regarding the size and extent of the ice sheet during the Last Glacial Maximum (LGM) and throughout the deglaciation. Direct observations of LGM LIS thickness are non-existent, however, due to ice surface elevations likely exceeding those of even the tallest summits in the northeastern United States (NE USA). …”
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Numerical Simulation of a Steel Weld Joint and Fracture Mechanics Study of a Compact Tension Specimen for Zones of Weld Joint by BENSARI AHMED, Ould Chikh El Bahri, Bouchouicha Benattou, Tirenifi Malika

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SimOutbreakSelection: a simulation-based tool to optimise sampling design and analysis strategies for detecting epidemic-driven selection by Cindy G. Santander, Ida Moltke

“…Abstract Throughout history, populations across species have been decimated by epidemic outbreaks. …”
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Towards Digital Twins: a Novel Model-Data Fusion Method for Simulating a Train Passing Through Curved Tracks by Shaodi Dong, Tengfei Jing, Wei Xia

“…When compared with other model-data fusion methods, the MDF-EKF method exhibits minimal deviations throughout the entire process of a train passing through curved tracks. …”
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How knee muscles and ground reaction forces shape knee buckling and ankle push-off in neuromuscular simulations of human walking by Alexandra Buchmann, Bernadett Kiss, Alexander Badri-Spröwitz, Daniel Renjewski

“…The knee is extended throughout the stance phase and begins to buckle just before push-off, with timing being crucial. …”
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Effects of high-fidelity simulation and e-learning methods on nursing students’ self-efficacy in patient safety: a quasi-experimental study by Kevser Ozata, Leyla Dinc

“…The professional self-efficacy and skills of nursing students regarding patient safety should be developed and assessed throughout their education. This study aimed to evaluate the impact of e-learning and high-fidelity simulation methods on the self-efficacy of nursing students. …”
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Air Quality-Driven Traffic Management Using High-Resolution Urban Climate Modeling Coupled with a Large Traffic Simulation by Janek Laudan, Sabine Banzhaf, Basit Khan, Kai Nagel

“…Building on prior work that establishes the coupling of the MATSim traffic model with the PALM-4U urban climate model, this second part focuses on implementing a feedback loop to inform traffic management decisions based on simulated air pollution concentration levels. The research explores how traffic volumes and atmospheric conditions, such as boundary layer dynamics, influence air quality throughout the day. …”
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Validation of real-time aging simulation of poly(lactic acid) (PLA) using accelerated aging in accordance with ASTM F1980 by Natalie Krug, Chaimae Chettouh, Jan-Christoph Zarges, Hans-Peter Heim

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"I still have not mastered that skill!" Medical student perspectives on a simulation-based evidence-based medicine competency assessment by Joey Nicholson, Caitlin Plovnick, Juliana Magro, Cees van der Vleuten, Anique de Bruin, Adina Kalet

“…Understanding how students experience and interact with a simulation-based assessment of EBM competence would enable us to improve the modality. …”
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Modeling, Control, and Simulation of Battery Storage Photovoltaic-Wave Energy Hybrid Renewable Power Generation Systems for Island Electrification in Malaysia by Nahidul Hoque Samrat, Norhafizan Bin Ahmad, Imtiaz Ahmed Choudhury, Zahari Bin Taha

“…Most of the islands throughout the world depend on fossil fuel importation with respect to energy production. …”
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Exploring the impact of flow dynamics on corrosive biofilms under simulated deep-sea high-pressure conditions using bio-electrochemostasis by Nicolò Ivanovich, Enrico Marsili, Xinhui Shen, Elena Messinese, Marcos, Pauliina Rajala, Federico M. Lauro, Federico M. Lauro, Federico M. Lauro

“…The results highlighted the device’s ability to closely replicate environmental conditions, thereby keeping bacterial communities metabolically active throughout the experiments and allowing for a more accurate assessment of the impact of MIC. …”
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Benzothiazinone analogs as Anti-Mycobacterium tuberculosis DprE1 irreversible inhibitors: Covalent docking, validation, and molecular dynamics simulations. by Mahmoud A A Ibrahim, Doaa G M Mahmoud, Alaa H M Abdelrahman, Khlood A A Abdeljawaad, Gamal A H Mekhemer, Tamer Shoeib, Mohamed A El-Tayeb, Peter A Sidhom, Paul W Paré, Mohamed-Elamir F Hegazy

“…Structural and energetical analyses were performed for the identified analogs against DprE1 throughout the 100 ns MD simulations, and the results demonstrated the great stability of the identified BTZ analogs. …”
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Molecular dynamic simulation studies of hemidesmus indicus-derived oleanen-3-yl acetate in stat3 based tumor signaling by J Renukadevi, V S Karthikha, J Sam Helinto, D. Prena, Arockiya Rabin A

“…Discussion: The RMSD values are maintained below at 2 Å throughout the simulation period, confirming the high structural stability of the ligand-protein complexes, while RMSF analysis is maintained at minimal fluctuation (<1.5 Å) involving key residues,  supporting the best ligand-protein interactions. …”
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Simulation-Based Rapid Development and Implementation of a Novel Barrier Enclosure for Use in COVID-19 Patients: The SplashGuard CG by Tine François, Laurence Tabone, Arielle Levy, Laurence Alix Seguin, Taher Touré, Carl Eric Aubin, Philippe Jouvet

“…Computer-aided design and simulation sessions throughout the entire process facilitated the rapid and safe implementation of the SplashGuard CG in different settings (intensive care unit, emergency department, and the operating room) during AGMPs such as bag-valve-mask ventilation, nasopharyngeal suctioning, intubation and extubation, and noninvasive ventilation. …”
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In-silico based discovery of potential Keap1 inhibitors using the strategies of pharmacophore screening, molecular docking, and MD simulation studies by Ekta Singh, Gurubasavaraja Swamy Purawarga Matada, Prasad Sanjay Dhiwar, Rajesh B. Patil, Rohit Pal

“…The leads (ASINEX 508, MiniMaybridgeHTS_01719, and ZINC 0000952883) were stabilized in the Keap1 binding cavity throughout 100 ns simulation, with average RMSD values of 0.100, 0.114, and 0.106 nm, respectively. …”
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Study on passive-active cooperative thermal control technology for space manipulator end effectors: Design, simulation, testing, and on-orbit validation by Min Zhang, Chunlong Liu, Richa Hu, Yantang Hua, Zhiyong Yang, Qingwen Wu, Liang Guo

“…This study provides a comprehensive analysis of the thermal design, simulation, testing, and orbital validation of a space manipulator's end effector. …”
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Development of a Lumped Parameter Model of Human Whole Body Circulatory Loop by Xun Liu, Chenghuai Mo, Jiaxing Li, Hongyi Yu, Sheng Hu, da Zhu, Puming Zhang, Yonghua Li

“…Utilizing this model, the hemodynamic characteristics of circulatory loops in healthy individuals, heart failure patients, and those experiencing cardiogenic shock are investigated, alongside transitions in circulatory states throughout the day. The model further simulates the pathological processes of two typical cardiovascular diseases: aortic valve stenosis and mitral valve regurgitation through parameter adjustments. …”
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Novel Quinoline- and Naphthalene-Incorporated Hydrazineylidene–Propenamide Analogues as Antidiabetic Agents: Design, Synthesis, and Computational Studies by Osama Alharbi, Wael H. Alsaedi, Mosa Alsehli, Saif H. Althagafi, Hussam Y. Alharbi, Yazeed M. Asiri, Ramith Ramu, Mohammed Al-Ghorbani

“…Molecular dynamics (MDs) simulations demonstrated that <b>7g</b> remained stable over a 100 ns simulation period, and the binding free energy estimates remained consistent throughout this time. …”
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Deconvoluting Protein (Un)folding Structural Ensembles Using X-Ray Scattering, Nuclear Magnetic Resonance Spectroscopy and Molecular Dynamics Simulation. by Alexandr Nasedkin, Moreno Marcellini, Tomasz L Religa, Stefan M Freund, Andreas Menzel, Alan R Fersht, Per Jemth, David van der Spoel, Jan Davidsson

“…However, they also suggest that the fully unfolded state is present at a low fraction throughout the investigated temperature interval, and that the (un)folding intermediate is highly populated at the thermal midpoint in line with the view that this intermediate can be regarded to be the denatured state under physiological conditions. …”
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