Upregulation of circGDI2 inhibits tumorigenesis by stabilizing the expression of RNA m6A demethylase FTO in oral squamous cell carcinoma by Yuwei Gu, Ling Sheng, Xiaoxiao Wei, Yuling Chen, Yuntao Lin, Zhangfu Li, Xiaolian Li, Huijun Yang, Yufan Wang, Hongyu Yang, Yuehong Shen

“…Overexpression of circGDI2 in OSCC cell lines led to decreased proliferation, migration, and invasion abilities. Knockdown of circGDI2 showed the opposite trend. …”
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Fe2O3 nanoparticles disrupt microstructure and reduce the viscoelasticity of simulated asthma airway mucus for potential airway mucus clearance applications by Jiayuan Zhong, Lei Shi, Zhiwei Liu, Kai Ni, Lei Liu, Yan Pan, Jingjing Li, Xiaowei Yu, Linhong Deng, Mingzhi Luo

“…In this study, we investigated the abilities of Fe2O3 nanoparticles dispersed in various media to alter the microstructure and rheological behaviors of simulated asthmatic AM. …”
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A Personalized Multimodal BCI–Soft Robotics System for Rehabilitating Upper Limb Function in Chronic Stroke Patients by Brian Premchand, Zhuo Zhang, Kai Keng Ang, Juanhong Yu, Isaac Okumura Tan, Josephine Pei Wen Lam, Anna Xin Yi Choo, Ananda Sidarta, Patrick Wai Hang Kwong, Lau Ha Chloe Chung

“…We propose a novel method of personalizing rehabilitation by aligning each patient’s specific abilities with the treatment options available. We collected 160 single trials of motor imagery using the multimodal BCI from 10 healthy participants. …”
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Summarizing clinical evidence utilizing large language models for cancer treatments: a blinded comparative analysis by Samuel Rubinstein, Aleenah Mohsin, Rahul Banerjee, Rahul Banerjee, Will Ma, Sanjay Mishra, Mary Kwok, Mary Kwok, Peter Yang, Jeremy L. Warner, Jeremy L. Warner, Andrew J. Cowan, Andrew J. Cowan

“…We objectively assessed the abilities of four commercially available LLMs to generate synopses for six treatment regimens in multiple myeloma and amyloid light chain (AL) amyloidosis.MethodsWe compared the performance of four LLMs: Claude 3.5, ChatGPT 4.0; Gemini 1.0 and Llama-3.1. …”
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Neural functions vary by return-to-sport status in participants with anterior cruciate ligament reconstruction: a retrospective cohort study using sub-bands of resting-state functi... by Hongyun Song, Hongyun Song, Hongyun Song, Hongyun Song, Hongyun Song, Sunan Zhu, Sunan Zhu, Sunan Zhu, Sunan Zhu, Zongyou Pan, Zongyou Pan, Zongyou Pan, Zongyou Pan, XiaoJing Yu, Bing Xiong, Xuesong Dai, Xuesong Dai, Xuesong Dai, Xuesong Dai

“…ObjectiveThis study aimed to characterize the differences in neural function among patients with different functional abilities 2 years after anterior cruciate ligament reconstruction (ACLR).DesignResting-state functional magnetic resonance imaging was performed to obtain blood-oxygen-level-dependent values for ACLR returned to sports coper participants (CP), non-coper participants (NP), and healthy controls (HC). …”
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The trajectory of anxiety symptoms during the transition from childhood to young adulthood is predicted by IQ and sex, but not polygenic risk scores by Ana Beatriz Ravagnani Salto, Giovanni A. Salum, Maurício Scopel Hoffmann, Marcos L. Santoro, André Zugman, Pedro M. Pan, Sintia I. Belangero, Lucas Toshio Ito, Victoria Fogaça Doretto, Marcos S. Croci, Marcelo J. A. A. Brañas, Carina deGiusti, Francisco Da Silva‐Jr, Sahâmia Martins Ribeiro, Euripedes Constantino Miguel, James F. Leckman

“…That said, the emotional needs of girls in late adolescence should be monitored, regardless of their cognitive abilities or high achievements.…”
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Identification of anoikis-related molecular patterns and the novel risk model to predict prognosis, tumor microenvironment infiltration and immunotherapy response in bladder cancer by Luochen Zhu, Feng Xiao, Yi Hou, Shenjun Huang, Yanyan Xu, Xiaohong Guo, Xinwei Dong, Chunlu Xu, Xiaolei Zhang, Haijuan Gu

“…Next, patients in the TCGA cohort were randomized into the train and test groups in a 1:1 ratio. Subsequently, the anoikis-related model was constructed to predict the prognosis via utilizing the univariate Cox, LASSO and multivariate Cox analyses, and validated internally and externally. …”
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Exploration and practice of comprehensive clinical rotation internship for undergraduate dental students by Yanting Liao, Yingjun Liu, Jing Huang, Yong Jiang, Wenshu Ge, Cong Fan, Na An

“…Descriptive statistics were employed to analyze the distribution of responses. The Chi-Square test was utilized to assess potential differences in response patterns between genders and between academic programs. …”
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Diet Patterns Featuring Western-Style and Low-Preparation Foods Differentially Relate to Cognitive Function in Early Childhood From the STRONG Kids 2 Birth Cohort Study by Arden L McMath, Shelby A Keye, Jennifer M Barton, Corinne N Cannavale, Samantha J Iwinski, Kelly F Bost, Sharon M Donovan, Naiman A Khan

“…A subsample of children completed a modified Eriksen flanker to measure attentional inhibition, a hearts and flowers switch task to assess cognitive flexibility, and the Woodcock Johnson Early Cognitive and Academic Development tests to assess academic abilities during preschool ages (between 4 and 6 y old). …”
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Effects of Video-Guided Active Breaks on Motor Competence of Schoolchildren with Special Education Needs by Alejandra Robles-Campos, Daniel Reyes-Molina, Karen Kracht-Suazo, Igor Cigarroa, Jaime Cárcamo-Oyarzun, Nicolas Martinez-Lopez, Margarita Perez-Ruiz, Alberto Grao-Cruces, Jorge Mota, Alberto Ruiz-Ariza, Fernando Muñoz Hinrichsen, Guillermo García-Pérez-de-Sevilla, Carlos Celis-Morales, Rafael Zapata-Lamana

“…These results indicate that the experimental group showed significantly greater improvements in object control, jumping, and running abilities compared to the control group. Conclusions: The active break program significantly improved motor skills in schoolchildren with special educational needs. …”
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WTAP/YTHDF1-mediated m6A modification amplifies IFN-γ-induced immunosuppressive properties of human MSCs by Quan Chen, Luoquan Ao, Qing Zhao, Lu Tang, Yanli Xiong, Yuchuan Yuan, Xiaofeng Wu, Wei Xing, Zhan Li, Wei Guo, Huaping Liang, Song Guo Zheng, Qizhou Lian, Di Lu, Weijun Wan, Xiang Xu

“…Further, functional capacity of T cells was tested using flow cytometry, and both DSS-induced colitis mice and CIA mice were constructed to clarify the effect of WTAP and YTHDF1 in MSC-mediated immunosuppression. …”
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Gut microbiota regulates exercise-induced hormetic modulation of cognitive functionResearch in context by Elisa Cintado, Pablo Muela, Lucía Martín-Rodríguez, Ignacio Alcaide, Patricia Tezanos, Klara Vlckova, Benjamín Valderrama, Thomaz F.S. Bastiaanssen, María Rodríguez-Muñoz, María L. de Ceballos, María R. Aburto, John F. Cryan, José Luis Trejo

“…We measured cognition through several tests and analysed microbiota composition comparing adult exercised animals to sedentary controls. …”
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Rate of depression in late-life in superannuated government employed center of ‎Guilan University of medical sciences by naeima khodadady, farzaneh sheikholeslami, shadman rezamasuoleh, mohamadali yazdani

“…Introduction: Aging is a word used for decreased life abilities with diminished biological ‎morbid. Emotional disorders make up a group of late‏ ‏‎-‎‏ ‏life mental disorders. …”
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Prevalence of mild cognitive impairment among former elite athletes without a history of sport-related concussions compared to the general older population: a protocol for a cross-... by Jingjing Ren, Qing Zhao, Haojie Li, Shuo Luan, Jiahui Cong, Hanzhi He, Jiaying Xu, Jinghua Qian

“…MCI and instrumental activities of daily living will be assessed using the Montreal Cognitive Assessment, Memtrax continuous recognition test and Lawton Instrumental Activities of Daily Living (IADL) scale. …”
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文冠果壳中总皂苷和总黄酮的抗氧化活性"Antioxidant activity of total saponins and total flavonoids from Xanthoceras sorbifolia Bunge shells" by 刘荣徽，魏媛，刘超，赵光鸿，杨洋，刘玉冰，汪甜甜，王珊，史高峰，王国英LIU Ronghui, WEI Yuan, LIU Chao, ZHAO Guanghong, YANG Yang

“…The relationship between antioxidant activity and structure-activity of the compounds extracted from Xanthoceras sorbifolia Bunge shells was analyzed.The results indicated that both total saponins and total flavonoids from Xanthoceras sorbifolia Bunge shells had certain scavenging abilities against these four types of free radicals, with the total flavonoids exhibiting higher scavenging capacities than the total saponins for all tested radicals.The structure-activity relationship analysis indicated that the differences in antioxidant activity between the total saponins and total flavonoids from Xanthoceras sorbifolia Bunge shells were related to their chemical structures.In conclusion, extracting total flavonoids from Xanthoceras sorbifolia Bunge shells and developing them as natural antioxidants can help enhance the comprehensive utilization value of Xanthoceras sorbifolia Bunge shells resources. …”
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The Effects of a Smartphone App (Feelee) to Enhance Adolescents’ Emotion Regulation Skills in a Forensic Outpatient Setting: Protocol for a Multiple Single-Case Experimental Design... by Merel M L Leijse, Levi van Dam, Thimo M van der Pol, René Breuk, Arne Popma

“…Quantitative analyses follow single-case experimental design methods, including visual analysis of individual trajectories, standardized mean difference permutation distance tests, and Cohen d at the group level. A 95% CI is calculated per participant to assess change reliability. …”
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Gatekeeper training for suicide prevention: a systematic review and meta-analysis of randomized controlled trials by Hui Liu, Chaohui Zheng, Yu Cao, Fanyan Zeng, Huiting Chen, Wei Gao

“…Abstract Introduction Gatekeeper training (GKT) aims to enhance suicide gatekeepers’ (GKs) abilities in assessing suicide risk, identify those at-risk and refer them. …”
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Expression profile, clinical significance, and biological function of insulin-like growth factor 2 messenger RNA-binding proteins in non–small cell lung cancer by Run Shi, Xinnian Yu, Yajing Wang, Jing Sun, Qi Sun, Wenjie Xia, Gaochao Dong, Anpeng Wang, Zhaojia Gao, Feng Jiang, Lin Xu

“…In vitro, knockdown of IGF2BP3 inhibited lung adenocarcinoma cell proliferation by inducing cell cycle arrest and apoptosis, and undermined abilities of migration and invasion, and overexpression of IGF2BP3 could promote malignant phenotypes in lung adenocarcinoma cells. …”
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Physiology and Pathophysiology of Marathon Running: A narrative Review by Lorin Braschler, Pantelis T. Nikolaidis, Mabliny Thuany, Daniela Chlíbková, Thomas Rosemann, Katja Weiss, Matthias Wilhelm, Beat Knechtle

“…It further positively affects hematopoiesis and cytotoxic abilities of natural killer cells, and may act neuroprotective on a long-term basis. …”
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Impact of regular physical activity and sports on school performance among girls and boys aged between 6 and 10 years (Impacto de la actividad física regular y los deportes en el r... by Amina Kheira Bekhechi, Belkacem Khiat

“…The socio-demographic data were collected by a questionnaire intended for the students of the two groups, and the administrative school results at the end of each quarter. An intelligence test of the CPM (Raven's Coloured Progressive Matrices) was administered at the end of the fifth trimester to assess the main cognitive abilities in both groups. …”
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