Fluorinated Porcine Bone-Derived Hydroxyapatite Promotes Vascularized Osteogenesis by Coordinating Human Bone Marrow Mesenchymal Stem Cell/Human Umbilical Vein Endothelial Cell Com... by Xiayi Wu, Chunxin Xu, Junming Feng, Shiyu Wu, Runheng Liu, Wei Qiao, Xin Luo, Shoucheng Chen, Zhipeng Li, Zhuofan Chen

“…In this study, fluorine-modified biogenic hydroxyapatite (FPHA) with varying fluorine concentrations was prepared and tested for its ability to promote vascularized osteogenesis. …”
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The Effects of Six Months of Exercise on Single- and Dual-Task Posture, Gait, and Functional Mobility Relative to Usual Care Alone Among People Living with Dementia: The ENABLED Pi... by Deborah A. Jehu, Ryan Langston, Charmi Patel, Andre Soares, Jennifer L. Waller, Ryan M. Carrick, Colleen Hergott, Lufei Young, William Hall, Dawnchelle Robinson-Johnson, Crystal Allen, Richard Sams, Mark Hamrick, Ying Huang, Haidong Zhu, Yanbin Dong

“…Usual care may reduce the ability to appropriately select cautious gait, as the usual care group exhibited faster dual-task gait speed at 6 months compared to the OEP plus usual care (<i>p</i> < 0.05), which was faster than their single-task gait speed. …”
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Development of peptone-based serum-free media to support Vero CCL-81 cell proliferation and optimize SARS-CoV2 viral production by Suryo Kuncorojakti, Diena Delaiah, Ahmad Aswin, Yulianna Puspitasari, Yeni Damayanti, Helen Susilowati, Diyantoro, Iwan Sahrial Hamid, Mohammad Anam Al Arif, Suwarno, Watchareewan Rodprasert

“…Six types of peptones were tested at varying concentrations to determine the top three candidates. …”
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Feasibility of urban waste for constructing Technosols for plant growth by Blanca Prado, Lucy Mora, Thalita Abbruzzini, Sebastián Flores, Silke Cram, Pilar Ortega, Armando Navarrete, Christina Siebe

“…The type of parental materials defined the majority of the Technosol characteristics as well as their ability to function as a plant support. The concentrations of readily available heavy and trace metals were not a limitation for plant growth. …”
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Pasteurized Akkermansia muciniphila improves irritable bowel syndrome-like symptoms and related behavioral disorders in mice by Maëva Meynier, Valentine Daugey, Geoffroy Mallaret, Sandie Gervason, Mathieu Meleine, Julie Barbier, Youssef Aissouni, Stéphane Lolignier, Mathilde Bonnet, Denis Ardid, Willem M. De Vos, Matthias Van Hul, Peter Suenaert, Amandine Brochot, Patrice D. Cani, Frédéric A. Carvalho

“…The cognitive performance and emotional state of the animals were also assessed by several tests in the C. rodentium infection model. The neuromodulation ability of pasteurized A. muciniphila was assessed on primary neuronal cells from mice dorsal root ganglia using a ratiometric calcium imaging approach. …”
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Decellularized cartilage scaffolds derived from wharton's jelly facilitate cartilage regeneration and inhibit angiogenesis by Fawei Gao, Shilong Su, Jun Qi, Zhigang Li, Chenggong Wang, Da Zhong

“…The avascular nature of articular cartilage severely limits its ability to self-repair after injury, which poses a challenge for clinical treatment, and tissue engineering aims to address this issue with scaffold-based strategies. …”
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Biomass, Physiological, and Antioxidant Activity Responses of Wheat Plants After Selenium Foliar Spray Under Water Deficit by Luís Rocha, Ermelinda Silva, Alexandre Gonçalves, Cátia Brito, Helena Ferreira, Carlos Matos, Aureliano C. Malheiro, Susana Araújo, José Lima-Brito, José Moutinho-Pereira

“…The ability of selenium (Se) to trigger modifications in plant metabolism, thereby triggering tolerance to abiotic stresses, is well established. …”
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Evaluating PlanetScope and UAV Multispectral Data for Monitoring Winter Wheat and Sustainable Fertilization Practices in Mediterranean Agroecosystems by Italo Moletto-Lobos, Katarzyna Cyran, Luciano Orden, Silvia Sánchez-Méndez, Belen Franch, Natacha Kalecinski, Francisco J. Andreu-Rodríguez, Miguel Á. Mira-Urios, José A. Saéz-Tovar, Pierre C. Guillevic, Raul Moral

“…However, its coarser resolution limited its ability to capture finer treatment-induced variability. …”
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Exploring the male fertility potential of medicinal plants from central and West African countries: A systematic review by Ismahil Adekunle Adeniyi, Olufunke Onaadepo, Daniel Owu, Ishak Abdi Jama, Augustine Oviosun, Ekom Monday Etukudo, Elna Owembabazi, Emeka Anyanwu, Patrick Maduabuch Aja, Josiah Ifie, Eric Aigbogun, Wusa Makena, Oluwatosin Olasheu Omoola, Comfort Ojochenemi Usman, Ibe Michael Usman

“…Treatment with the plant extracts were associated with increased sperm count, motility, and viability, and improved histoarchitecture of the testes. However, only a few of the included studies chemical characterized the plant used for the study; ultraviolet spectrophotometry 4 % (1/25), gas chromatography-mass spectrometry 12 % (3/25), high-performance liquid chromatography 8 % (2/25), nuclear magnetic resonance 4 % (1/25), fourier transform infrared spectroscopy 4 % (1/25) Conclusion: This review highlights the promising fertility-enhancing potential of plant species used in C&W Africa, demonstrating their ability to improve male reproductive health through antioxidative, anti-inflammatory, and hormonal modulation pathways. …”
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Insights into alleviating high brittleness of TiCu compound by doping C and O as interstitials: First-principle calculations by Yujie Tao, Yibo Liu, Yue Liu, Qi Sun, Haoyu Kong, Qingjie Sun

“…Seven different doping models were tested to determine the optimal concentration of C and O, with a comprehensive analysis of their impacts on the phase stability, mechanical properties, and electronic structure of TiCu conducted via first-principle calculations. …”
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Bergamot (<i>Citrus bergamia</i>): A Potential New Nutraceutical Against Cellular and Physiological Alterations Induced by Emerging Contaminants in Sentinel Organisms by Federica Impellitteri, Cristiana Roberta Multisanti, Kristian Riolo, Giorgia Zicarelli, Miriam Porretti, Giovanna Cafeo, Marina Russo, Paola Dugo, Giuseppa Di Bella, Giuseppe Piccione, Alessia Giannetto, Caterina Faggio

“…The analyses included cell viability of haemocytes and DG cells (trypan blue exclusion assay and the neutral red retention test); the ability of DG cells to regulate their volume (RVD); haemocyte phagocytic activity; expression of genes involved in antioxidant response (<i>Cu/ZnSOD, MnSOD, Hsp70</i>, and <i>CYP4Y</i>) on gills and DG; the energy efficiency of the organism through byssus production; and the measurement of key macromolecules, including total lipid and fatty acid content, total protein, tocopherols and carotenoids, which play a key role in maintaining physiological and metabolic functions in the organism. …”
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Galangin reduces MPTP-induced dopamine neuron injury via the autophagy dependent-PI3K/AKT pathway by Liping Huang, Liping Huang, Qiaofeng Li, Jingyi Wu, Yingying He, Junwei Huang, Sipeng Xie, Canfeng Yang, Qingling Ruan, Zhongliu Zhou, Minzhen Deng, Minzhen Deng

“…Techniques including network analysis, transcriptomic analysis, rotarod test, enzyme-linked immunosorbent assay (ELISA), qRT-PCR, western blotting, immunohistochemistry, immunofluorescence, and hematoxylin–eosin (HE) were employed to unveil the molecular changes induced by Galangin.ResultsThe network pharmacological analysis showed 301 targets related to Galangin, and 2,858 genes related to PD. …”
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Protective Effect of Allergen Immunotherapy in Patients With Allergic Rhinitis and Asthma Against COVID-19 Infection: Observational, Nationwide, and Multicenter Study by Rundong Qin, Yan Feng, Huanping Zhang, Beibei Zhao, Wei Lei, Hongying Sun, Lili Zhi, Zhongsheng Zheng, Siqin Wang, Yafeng Yu, Shengxue Jiang, Changshan Liu, Xingkai Ma, Hui Ma, Huiying Wang, Hang Lin, Qiaojie He, Lingying Wu, Yingying Zhai, Honglue Lu, Shi Chen, Yan Ma, Xiaohong Jin, Shan Deng, Nanshan Zhong, Ruchong Chen, Jing Li

“…Although allergen immunotherapy (AIT) alters the course of allergies, there is limited evidence from clinical practice demonstrating its ability to enhance the host defense against pathogens. …”
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Seeking Correlation Among Porin Permeabilities and Minimum Inhibitory Concentrations Through Machine Learning: A Promising Route to the Essential Molecular Descriptors by Sara Boi, Silvia Puxeddu, Ilenia Delogu, Domenica Farci, Dario Piano, Aldo Manzin, Matteo Ceccarelli, Fabrizio Angius, Mariano Andrea Scorciapino, Stefan Milenkovic

“…Conversely, when permeation ability is low, other factors play the most significant role in antimicrobial potency. …”
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7-α-O-Methylmorroniside ameliorated brain injury in 5×FAD mice by regulating the gut microbiome and NMDAR2B by Fengxiao Hao, Fengxiao Hao, Mengnan Zeng, Mengnan Zeng, Bing Cao, Bing Cao, Xiwen Liang, Zhiyou Hao, Zhiyou Hao, Kaili Ye, Kaili Ye, Xinmian Jiao, Xinmian Jiao, Weisheng Feng, Weisheng Feng, Xiaoke Zheng, Xiaoke Zheng

“…In the present study, we investigated the mechanism by which MorA ameliorated brain injury in 5×FAD mice by using gut microbiota (GM) combined with in vitro and in vivo pharmacological experiments. Behavioral tests revealed that MorA could enhance learning and memory ability and improve cognitive impairment. …”
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Anticancer Potential of <i>Cymbopogon citratus</i> L. Essential Oil: In Vitro and In Silico Insights into Mitochondrial Dysfunction and Cytotoxicity in Cancer Cells by Tamara Maksimović, Daliana Minda, Codruța Șoica, Alexandra Mioc, Marius Mioc, Daiana Colibășanu, Alexandra Teodora Lukinich-Gruia, Maria-Alexandra Pricop, Calin Jianu, Armand Gogulescu

“…Moreover, LEO treatment decreased all mitochondrial respiratory rates, thus suggesting its ability to induce impairment of mitochondrial function. …”
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Osteogenic shift in the adipose-derived stem cells of Acomys cahirinus is linked to impaired adipose tissue self-renewal by M. Boldyreva, M. Boldyreva, E. Zubkova, E. Trubkina, E. Trubkina, M. Agareva, M. Agareva, S. Michurina, N. Alekseeva, I. Beloglazova, E. Ratner, Ye Parfyonova, Ye Parfyonova, I. Stafeev

“…The mesenchymal phenotype of ADSC was confirmed by surface markers expression and differentiation ability. Proliferation and migration of ADSC were assessed by metabolic tests and microscopy. …”
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Combining the RCAS/tv-a retrovirus and CRISPR/Cas9 gene editing systems to generate primary mouse models of diffuse midline glioma by Sophie R. Wu, Julianne Sharpe, Joshua Tolliver, Abigail J. Groth, Reid Chen, María E. Guerra García, Vennesa Valentine, Nerissa T. Williams, Sheeba Jacob, Zachary J. Reitman

“…However, current midline glioma GEMM approaches are limited in their ability to multiplex perturbations and/or target specific cell lineages in the brain for genetic manipulation. …”
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LC risk score – development and evaluation of a scale for assessing the risk of developing long COVID by Mateusz Babicki, Mateusz Lejawa, Tadeusz Osadnik, Joanna Kapusta, Maciej Banach, Piotr Jankowski, Agnieszka Mastalerz-Migas, Żaneta Kałuzińska-Kołat, Damian Kołat, Michal Chudzik

“…Model predictive ability was evaluated based on the ROC curve and the AUC value. …”
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A digital intervention to improve mental health and interpersonal resilience for young people who have experienced online sexual abuse: the i-Minds non-randomised feasibility clini... by Sandra Bucci, Filippo Varese, Ethel Quayle, Kim Cartwright, Amanda Larkin, Cindy Chan, Prathiba Chitsabesan, Victoria Green, William Hewins, Matthew Machin, Alice Newton, Erica Niebauer, John Norrie, Gillian Radford, Cathy Richards, Marina Sandys, Victoria Selby, Sara Shafi, Jennifer Ward, Pauline Whelan, Matthias Schwannauer

“…Facilitators included the distinct nature and specificity of the i-Minds app for the target group and its ability to support young people on service waiting lists. …”
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