Comparative effect of different plasticizers on physicochemical properties of hydroxypropyl methyl cellulose (HPMC)- based films appropriate for gilthead seabream packaging by Evmorfia Athanasopoulou, Enrico Maurizzi, Francesco Bigi, Andrea Quartieri, Andrea Pulvirenti, Theofania Tsironi

“…The hydrophobic films had also better water barriers compared to films with glycerol. All tested packaging materials resulted in similar preservative effect on packed gilthead seabream fillets, leading in shelf life 7–8 days at 2 °C. …”
Get full text

Design and Evaluation of a Crosslinked Chitosan-Based Scaffold Containing Hyaluronic Acid for Articular Cartilage Reconstruction by Salim Hamidi, Mickael Maton, Feng Hildebrand, Valérie Gaucher, Cédric Bossard, Frédéric Cazaux, Jean Noel Staelens, Nicolas Blanchemain, Bernard Martel

“…Scaffolds loaded with ciprofloxacin (CFX) demonstrated their ability to deliver therapeutic agents, as the CFX loading capacity was promoted by CHT–CFX interactions. …”
Get full text

An effective method for preparation of high purity oligohexamethylene guanidine salts by I. S. Ivanov, D. O. Shatalov, S. A. Kedik, I. P. Sedishev, S. V. Beliakov, K. N. Trachuk, V. V. Komarova

“…Given that microorganisms can become resistant to certain groups of drugs and considering also their ability to form biofilms, the development of new drugs that are active against adapted microflora is required. …”
Get full text

Outcome prediction model for patients with unresectable hepatocellular carcinoma treated with targeted therapy by Qiang Ruan, Xiaohui Wang, Qiang Li, Yu Tao, Yang Xun, Hua Yang, Han Zhao, Jinfeng Lu, Dazhi Yang, Yifan Chen, Li Wei

“…In the validation set, the TUHP model was tested and compared with other prognostic model. The results showed that the TUHP model was also significantly associated with OS and PFS and exhibited greater discriminative ability than the existing prognostic models. …”
Get full text

Design of a Sensory Device for the Characterization of the Volatile Organic Compounds Fingerprint in the Breath of Dairy Cattle by Simone Giovinazzo, Elio Romano, Carlo Bisaglia, Aldo Calcante, Ezio Naldi, Roberto Oberti, Alex Filisetti, Gianluigi Rozzoni, Massimo Brambilla

“…For this reason, we developed a sensory device, tested in the laboratory, to detect acetone concentrations ranging from 1 to 10 ppm (concentrations typically detected in the cow’s breath), and we look to verify the electronic nose’s potential as a non-invasive diagnostic tool for ketosis. …”
Get full text

A Metabolomics-Based Approach for Diagnosing NAFLD and Identifying Its Pre-Condition Along the Potential Disease Spectrum by Masanori Nojima, Takeshi Kimura, Yutaka Aoki, Hirotaka Fujimoto, Kuniyoshi Hayashi, Junya Ohtake, Mariko Kimura-Asami, Kazuhiko Suzuki, Kevin Urayama, Masaaki Matsuura, Taka-Aki Sato, Katsunori Masuda

“…While each metabolite exhibited a limited diagnostic ability for NAFLD when used individually, compared with BMI, the model constructed using the LASSO demonstrated adequate diagnostic power (area under the curve [AUC] 0.866, 95% confidence interval 0.847–0.885 in test set) and even for lean (BMI < 23) populations (AUC for LASSO 0.828, for BMI 0.78). …”
Get full text

Integration of Multifunctionality in a Colloidal Self‐Repairing Catalyst for Alkaline Water Electrolysis to Achieve High Activity and Durability by Yoshiyuki Kuroda, Daiji Mizukoshi, Vinay Yadav, Tatsuya Taniguchi, Yuta Sasaki, Yoshinori Nishiki, Zaenal Awaludin, Akihiro Kato, Shigenori Mitsushima

“…Herein, hybrid cobalt hydroxide nanosheets (Co‐ns), with a high deposition (repairing) rate, and β‐FeOOH nanorods (Fe‐nr), with high oxygen evolution reaction (OER) ability, are electrostatically self‐assembled into composite catalysts. …”
Get full text

Influence of zirconium dioxide (ZrO2) and magnetite (Fe3O4) additions on the structural, electrical, and biological properties of Bioglass® for metal implant coatings by Imen Hammami, Manuel Pedro Fernandes Graça, Sílvia Rodrigues Gavinho, Joana Soares Regadas, Suresh Kumar Jakka, Ana Sofia Pádua, Jorge Carvalho Silva, Isabel Sá-Nogueira, Isabel Sá-Nogueira, João Paulo Borges

“…BackgroundThe growing need for durable implants, driven by aging populations and increased trauma cases, highlights challenges such as limited osseointegration and biofilm formation. 45S5 Bioglass® has shown promise due to its bioactivity, antimicrobial properties, and ability to enhance osseointegration through electrical polarization. …”
Get full text

The Role of Lactobacillus reuteri DSMZ17648 for Helicobacter pylori eradication therapy (Review of literature and advisory council resolution, February 28, 2018) by V. T. Ivashkin, O. P. Alekseyeva, A. Yu. Baranovsky, Ye. K. Baranskaya, Ye. V. Beloborodova, T. A. Kolesov, N. V. Korochanskaya, K. . Lang, T. L. Lapina, I. V. Mayev, M. V. Mokshina, D. L. Nepomnyashchy, Ye. V. Onuchina, R. G. Sayfutdinov, T. H. Sviridova, V. I. Simanenkov, A. V. Tkachev, A. S. Trukhmanov, L. P. Faizova, I. B. Khlynov, O. B. Khlynova, A. A. Sheptulin

“…L. reuteri strain DSM17648 which was chosen from over 700 wildtype strains of Lactobacillus spp. possess the ability for selective adhesion to H. pylori in vivo in the gastric media. …”
Get full text

Consumer behavior at sale point and consumption according to strawberry quality: How to use those data to evaluate food waste?entrepot.recherche.data.gouv.fr by Emma Pignères, Marine Masson, Steven Duret, David Blumenthal, Maëlle-Ahou Gouton, Nathalie Gontard, Hélène Angellier-Coussy, Valérie Guillard, Fanny Coffigniez, Sébastien Gaucel

“…Seven scenarios were tested by varying the initial deterioration of strawberries at the supermarket. …”
Get full text

A Case Series Report on the Effect of Tofacitinib on Joint Inflammation and Gut Microbiota Composition in Psoriatic Arthritis Patients Naive to Biologic Agents by Andrea Picchianti Diamanti, Concetta Panebianco, Valeria Di Gioia, Ilaria Anna Bellofatto, Simonetta Salemi, Roberta Di Rosa, Giorgio Sesti, Gabriele Nalli, Gerardo Salerno, Etta Finocchiaro, Bruno Laganà

“…The clinical response was assessed using validated scores (DAPSA, ASDAS, and BASDAI), laboratory tests, and US assessment of the target joint and enthesis. …”
Get full text

Denoising of electromagnetic data from different geological blocks using a hybrid PSO-GWO algorithm and CNN by Zhong-Yuan Liu, Zhong-Yuan Liu, Zhong-Yuan Liu, Di-Quan Li, Di-Quan Li, Di-Quan Li, Yecheng Liu, Yecheng Liu, Yecheng Liu, Xian Zhang, Xian Zhang, Xian Zhang

“…The method was tested on WFEM data from the Sichuan Changning Block and the Shanxi Xinyuan Coal Mine area. …”
Get full text

A New Antibody–Cytokine Construct Targeting Natural Killer Cells: An Immunotherapeutic Approach to Chronic Lymphocytic Leukemia by Michela Flego, Mauro Andreotti, Francesca Romana Mauro, Maria Beatrice Arasi, Silvia Zamboni, Zuleika Michelini, Sara Pepe, Clementina Maria Galluzzo, Roberta Amici, Diego Moricoli, Chiara Mazzei, Alessandro Ascione, Alessandra Mallano

“…We designed and developed a cis-acting immunocytokine composed of an anti-CD56 single-chain Fragment variable (scFv) and IL15, labeled scFvB1IL15. scFvB1IL15 was tested in vitro on peripheral blood mononuclear cells (PBMCs) obtained from both different healthy donors (HDs) and CLL patients in order to evaluate its ability to target NK cells and enhance their activation and NK-mediated directed cytotoxicity. scFvB1IL15 specifically induced strong degranulation and cytokine and chemokine production in NK cells in both HD- and CLL patient-derived PBMC samples. …”
Get full text

Peculiarities of Functional Connectivity—including Cross-Modal Patterns—in Professional Karate Athletes: Correlations with Cognitive and Motor Performances by Beatrice Berti, Davide Momi, Giulia Sprugnoli, Francesco Neri, Marco Bonifazi, Alessandro Rossi, Maria M. Muscettola, Roberto Benocci, Emiliano Santarnecchi, Simone Rossi

“…All subjects underwent an extensive cognitive test battery for the identification of individual multidimensional cognitive profile and rs-fMRI scans investigating functional connectivity (FC). …”
Get full text

Investigation of Phagocyte Functions in Pseudomonas-Colonized Cystic Fibrosis Patients by Handan Duman Şenol, Meral Barlık, Ezgi Topyıldız, Figen Gülen, Güzide Aksu, Necil Kütükçüler, Esen Demir, Neslihan Edeer Karaca

“…The neutrophils oxidative burst activity and the chemotactic ability of the CF patients did not differ from those of the controls. …”
Get full text

Colorado Pediatric Airway Score (COPUR) as a Predictor of Intubation Difficulty in Children Aged 1-8 Years by Christopher Kapuangan, Aries Perdana, Fulki Fadhila, Andi Ade Wijaya Ramlan, Raihanita Zahra, Komang Ayu Ferdiana, Rahendra Rahendra

“…The score demonstrated good discriminative ability (AUC-ROC: 0.770, 95% CI: 0.685–0.842) and suitable calibration (Hosmer-Lemeshow test, p = 0.584). …”
Get full text

Thermal Tolerance and Host Plant Suitability of <i>Bemisia tabaci</i> MED (Gennadius) in Brazilian Legume Crops by Daniel de Lima Alvarez, Rafael Hayashida, Daniel Mariano Santos, Felipe Barreto da Silva, Cristiane Müller, Renate Krause-Sakate, William Wyatt Hoback, Regiane Cristina de Oliveira

“…Temperatures between 23 °C and 32 °C were the most suitable for <i>B. tabaci</i> MED development and viability across all tested host plants, whereas 35 °C proved harmful for insects reared on legumes. …”
Get full text

Persistence of Reptile DNA in a Terrestrial Substrate: A Case Study Using the Eastern Indigo Snake by Leah R. N. Samuels, Houston C. Chandler, Michelle Hoffman, John A. Kronenberger, Michele Elmore, Robert Aldredge, Benjamin S. Stegenga, James E. Bogan Jr., Mark A. Davis, Stephanie Hertz, Michael K. Schwartz, Taylor Wilcox

“…However, knowledge gaps regarding eDNA deposition and persistence in this system currently limit our ability to apply eDNA sampling effectively at the landscape scale. …”
Get full text

Development and validation of a clinical prediction model for osteoporosis diagnosis by lumbosacral X-ray and radiomics by Xiaofeng Chen, Xiaofeng Chen, Dongling Cai, Dongling Cai, Hao Li, Weijun Guo, Qian Li, Qian Li, Jinjun Liang, Junxian Xie, Jincheng Liu, Zhen Xiang, Wenxuan Dong, Sihong OuYang, Zhuozheng Deng, Qipeng Wei

“…Upon comprehensive performance analysis across different models, the clinical and radiomics model emerged as the most effective. The training set and test set area under the curves (AUCs) were 0.818 and 0.740, respectively. …”
Get full text

Meloxicam mitigated methylglyoxal-induced glycative stress in rats by Talha Fayyaz, Ghulam Abbas, Hammad Ahmed, Najeeb Khatian, Shumaila Usman, Uzair Nisar, Noor Ain, Yamna Khurshid, Syed Ali

“…The present study evaluated meloxicam, a clinically used NSAID, for its ability to offer protection against glycative stress.Materials and Methods: Methylglyoxal (MGO; 17.25 mg/kg) was administered for two weeks to create a rat model of glycative stress. …”
Get full text