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10381
Jujuboside B Inhibits the Proliferation and Migration of Non-Small Cell Lung Cancer H1299 Cells Through Inhibiting PI3K/Akt and Wnt/β-Catenin Pathways
Published 2025-06-01“…Jujuboside B (JUB) is one of the main bioactive components in ZSS; however, JUB’s roles in the treatment of lung cancer, and the mechanism have not been well reported.Objective: This study intends to evaluate the effects of JUB on the proliferation and migration of non-small cell lung cancer H1299 cells (NC-1299 cells), as well as the potential related regulatory mechanism.Methods: The viability, migration and invasive ability of NC-1299 cells were analyzed by CCK8, wound-healing, transwell invasion, and the expression of proteins was analyzed through Western blotting experiments.Results: It showed that 160 and 320 μmol/L JUB significantly inhibited the proliferation of NC-1299 cells, reduced the cell migration in the wound healing test, and decreased the cell number of clonal assay (P < 0.05). …”
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10382
Changes in postural stability induced by a ball-and-board game designed from a systems perspective
Published 2025-05-01“…In conclusion, our game led to a postural reorganization that encourages us to test it in clinical settings.…”
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10383
Integration of Sensor Data and Mathematical Modeling of Underwater Robot Behavior Using a Digital Twin
Published 2025-06-01“…The Unity Game Environment was used to visualize and test the model. It created a digital twin module with the ability to display the system state in real time. …”
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10384
The evaluation of cold tolerance of winter soft wheat sprouts according to a degree of root growth speed repair
Published 2018-05-01“…The criteria can characterize not only primary tolerance and adaptive opportunities of the variety, but also its ability to homeostasis. Due to the conducted study, there have been found varietal differences of the tested parameter among the varieties belonging to various species of winter soft wheat (lutescens, suberythrospermum, gosteonum), as well as among the varieties belonging to single specie (lutescens). …”
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10385
The role of large language models in improving the readability of orthopaedic spine patient educational material
Published 2025-05-01“…This study assessed the readability of OrthoInfo spine articles and investigated the ability of large language models (LLMs) to improve readability. …”
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10386
Sistem Pendukung Keputusan Untuk Penerimaan Beasiswa Dengan Metode Simple Additive Weighting (SAW) Pada Smkn 1 Ciomas Kabupaten Bogor
Published 2020-03-01“…Therefore, it is necessary to build a decision support system for receiving a scholarship by using Simple Additive weighting method (SAW) which has the ability to solve the problem of multiple criteria. …”
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10387
Examining a brief web and longitudinal app-based intervention [Wysa] for mental health support in Singapore during the COVID-19 pandemic: mixed-methods retrospective observational...
Published 2024-12-01“…Engagement and retention were evaluated through usage data, and T-tests were used to compare engagement and retention between the app and website. …”
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10388
Construction and Evaluation of Intimate Partner Homicide Prediction Model
Published 2024-12-01“…The Hosmer-Lemeshow goodness of fit test result of the model was χ2=13.158, P=0.068. …”
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10389
Bioinspired activation strategies for Peano-HASEL artificial muscle.
Published 2025-01-01“…Future work should focus on more complex artificial muscle arrangements and test activation strategies in practical experiments.…”
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10390
Provider advice, pregnant persons’ expectations, and actual gestational weight gain among United States military health care beneficiaries: a secondary analysis of a randomized con...
Published 2024-11-01“…We used regression models to assess the predictive ability of expectations about GWG on actual GWG. Results Participants with higher baseline BMIs were more likely to expect excessive GWG as defined by the National Academy of Medicine (NAM; Overweight: 46.3%, Obesity: 65.4%). …”
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10391
DNA extraction protocols for animal fecal material on blood spot cards.
Published 2025-01-01“…Further, the suitability of Illumina shotgun metagenomic sequencing at 20 million paired-end (PE) read depth per sample was assessed on its ability to successfully characterize the taxonomic and functional aspects of the resulting fecal microbiome.…”
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10392
PENGEMBANGAN MULTIMEDIA INTERAKTIF BERBASIS PROBLEM BASED LEARNING PADA MATERI STATISTIKA
Published 2025-02-01“…The research instruments used include interview guidelines, questionnaires, observation sheets, and MPSA tests. Data analysis involved descriptive and descriptive statistical techniques. …”
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10393
Emergency Medical Services Calls for Service at Adult Detention Centers: A Descriptive Study
Published 2025-07-01“…Further study is needed to better understand the healthcare needs of these patients, including ability to consent.…”
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10394
Repeated-Sprint Training in Hypoxia Induced by Voluntary Hypoventilation at Low Lung Volume: A Meta-analysis
Published 2025-05-01“…Standardized mean difference (SMD) was determined for repeated-sprint ability related variables [i.e., best and mean performance (RSAbest and RSAmean), sprint decrement score (Sdec)] and maximal blood lactate concentration ([La]max). …”
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10395
Application of the Bidirectional Encoder Representations from Transformers Model for Predicting the Abbreviated Injury Scale in Patients with Trauma: Algorithm Development and Vali...
Published 2025-05-01“…It has a high generalization ability in external datasets.…”
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10396
A comprehensive evaluation of satellite-based and reanalysis soil moisture products over the upper Blue Nile Basin, Ethiopia
Published 2024-12-01“…After applying bias correction, the Kolmogorov-Smirnov two-sample t-tests, Bonferroni correction, and statistical error metrics, the evaluation reveals that all products, except NASA-GLDAS, effectively capture soil moisture dynamics. …”
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10397
The Demographic and Clinical Characteristics, Prognostic Factors, and Survival Outcomes of Head and Neck Carcinosarcoma: A SEER Database Analysis
Published 2024-11-01“…These nomograms enhance the ability to predict patient prognosis and personalize treatment strategies.…”
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10398
Urban Toponyms as Linguistic Markers of “Owning” the Space
Published 2025-04-01“…An important feature implying that an urban object is fixed on the mental map of a local community is its ability to be a reference point in everyday city life and communication. …”
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10399
The Impact of Smoking, Age, and BMI on Bone Healing in Patients Underwent Minimally Invasive Plate Osteosynthesis Fixation for Long Bones Fractures
Published 2024-12-01“…These injuries often require surgical intervention, with techniques like Minimally Invasive Plate Osteosynthesis (MIPO) being favored due to their ability to minimize soft tissue damage while providing stable fixation. …”
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10400
A New [PMo<sub>12</sub>O<sub>40</sub>]<sup>3−</sup>-Based Ni<sup>II</sup> Compound: Electrochemical and Photocatalytic Properties for Water Pollutant Removal
Published 2025-05-01“…A polyoxometalate-based metal–organic complex with the ability to treat pollutants in water was obtained under hydrothermal conditions, namely [Ni(H<sub>2</sub>L)(HL)<sub>2</sub>](PMo<sub>12</sub>O<sub>40</sub>)·3H<sub>3</sub>O·4H<sub>2</sub>O (<b>1</b>) (H<sub>2</sub>L = 4,4′-(1H,1′H-[2,2′-biimidazole]-1,1′-diyl)dibenzoicacid). …”
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