An innovative curriculum development experience: Emergency Medical Dispatch role in the Healthcare Transformation Vision of Saudi Arabia by Yousef M. Alsofayan, Kharsan M. Almakhalas, Abdullah A. Alabdali, Mohammed S. Arafat, Nawfal A. Aljerian, Ameera A. Cluntun, Waad S. Alshammari, Salman S. Alharthi, Fahad S. Alhajjaj, Jalal M. Alowais, Sami J. Alsolamy, Bandr Y. Mzahim, Abdulrahman Y. Sabbagh

“…Results The development of the EMD program utilized a consecutive mixed approach starting with a competency-based with backward design method to ensure the achievement of targeted outcomes followed by the Kern Six-step curriculum development model, namely: (1) problem identification and general need assessment; (2) targeted need assessment; (3) goals and objectives; (4) educational strategies; (5) implementation; and (6) evaluation and feedback. …”
Get full text

Testing a parent support intervention to improve success of first year students at a historically-Black University (HBCU) by Sharron Xuanren Wang, Lawita Cheatham-Hemphill, Melissa A. Harrington

“…At our Historically Black University, we developed a year-long communication plan targeted at parents of first-year students and aimed at boosting the educational cultural capital of parents and cultivating a supportive environment to enhance students’ educational experiences and outcomes. …”
Get full text

Impact of Learning Management Systems and Digital Skills on TPACK Development Among Pre-service Mathematics Teachers by Muh Fitrah, Caly Setiawan, Widihastuti Widihastuti, Anastasia Sofroniou, Nur Azizatur Rahmawati, Arina Arina, Sri Ratna Sari, Iskandar Iskandar

“…Universities and school administrators should implement targeted training programs to enhance LMS utilization and help pre-service teachers develop strong TPACK competencies. …”
Get full text

A Supplemental Women’s Health Questionnaire for Women Veterans With Military Environmental Exposures: Project Development and Implementation by Leah N Eizadi, Mehret T Assefa, Jordan M Nechvatal, G Marina Veltkamp, Abou Ibrahim-Biangoro, Maheen M Adamson, Jennifer S Jennings

“…ObjectiveThe primary objective of this project is to (1) describe the development and implementation of a comprehensive health questionnaire for women veterans, (2) systematically describe and characterize the health conditions of women seeking care for MEE-related health concerns, and (3) use findings to inform clinic policies and develop targeted programs. …”
Get full text

Nutrient-adequate diets with the lowest greenhouse gas emissions or price are the least acceptable—insights from dietary optimisation modelling using the iOTA model® by Mahya Tavan, Nick W. Smith, Andrew J. Fletcher, Andrew J. Fletcher, Jeremy P. Hill, Jeremy P. Hill, Warren C. McNabb

Get full text

Enhancing social-emotional skills in early childhood: intervention study on the effectiveness of social and emotional learning by Rikuya Hosokawa, Yuki Matsumoto, Chizuko Nishida, Keiko Funato, Aki Mitani

“…A whole-class approach can reach more children, maximizing the preventive effects. The program can improve academic performance and social adaptation, contributing to the long-term development of psychological health and social skills. …”
Get full text

Efficacy, safety, and biomarker analyses of bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in patients with advanced non-small cell lung cancer by Arun Rajan, Renee N Donahue, Jeffrey Schlom, James L Gulley, Elizabeth Lamping, Osama Rahma, Houssein Abdul Sater, Jennifer L Marté, Beatriz Walter-Rodriguez, Yulia Vugmeyster, Yo-Ting Tsai, Shania Bailey, Wiem Lassoued, Richy Agajanian, Andrew Weisman, Rena Ito, Masashi Sato, Andreas Machl

Get full text

Mitigating Doxorubicin‐Induced Cardiotoxicity and Enhancing Anti‐Tumor Efficacy with a Metformin‐Integrated Self‐Assembled Nanomedicine by Jiaxin Huang, Jieru Yang, Yuanying Yang, Xiaofeng Lu, Juan Xu, Shan Lu, Hong Pan, Wenhu Zhou, Wenqun Li, Songwen Chen

“…PMDDH integrates metformin into a polyethyleneimine‐based bioactive excipient (PMet), with Dox intercalated into double‐stranded DNA and a hyaluronic acid (HA) coating to enhance tumor targeting. The PMDDH significantly improves the pharmacokinetics and tumor‐targeting capabilities of Dox, while metformin enhances the drug's anti‐tumor activity by downregulating programmed cell death ligand 1 (PD‐L1) and activating the AMP‐activated protein kinase (AMPK) signaling pathway. …”
Get full text

Randomized Controlled Trial of the Effectiveness of Genetic Counseling and a Distance, Computer-Based, Lifestyle Intervention Program for Adult Offspring of Patients with Type 2 Di... by M. Nishigaki, Y. Tokunaga-Nakawatase, J. Nishida, C. Taru, I. Miyawaki, H. Sanada, K. Kazuma

“…Relatives of type 2 diabetic patients are at a high risk of developing type 2 diabetes and should be regarded as target of intervention for diabetes prevention. …”
Get full text

Prevalence and antimicrobial resistance of salmonella isolates from backyard chicken in Maryland lower eastern shore, USA by Janak Dhakal, Sandesh Chapagain, Richard Y. Otwey, Jennifer Timmons, Ariel Clay

“…In this study, we investigated the prevalence, serotype, and antibiotic resistance of Salmonella from backyard poultry as part of a youth development initiative by the University of Maryland Eastern Extension Department's 4-H program. …”
Get full text

Pre-breeding in alfalfa germplasm develops highly differentiated populations, as revealed by genome-wide microhaplotype markers by Cesar A. Medina, Dongyan Zhao, Meng Lin, Manoj Sapkota, Alexander M. Sandercock, Craig T. Beil, Moira J. Sheehan, Brian M. Irish, Long-Xi Yu, Hari Poudel, Annie Claessens, Virginia Moore, Jamie Crawford, Julie Hansen, Donald Viands, Michael D. Peel, Neal Tilhou, Heathcliffe Riday, E. Charles Brummer, Zhanyou Xu

“…This study demonstrates that individual plants in BASE populations possess high genetic diversity, low interpopulation distances, and minimal inbreeding, characteristics that are essential for base-broadening selection. The populations developed in this project serve as valuable sources of novel alleles for North American alfalfa breeding programs, offering breeders access to diverse, regionally adapted pools for improving various alfalfa traits.…”
Get full text

On the development of mechanisms and tools for expanding the value of full-cycle science and technology projects using the TPRL methodology by A. V. Komarov, D. A. Matveev, A. V. Filimonov, A. V. Sartory

“…The use of professional competences of techno-brokers is confirmed by the positive experience of the Program for the Development and Commercialization of Projects of the Federal Targeted Program “Research and Development in Priority Areas of the Scientific and Technological Complex of Russia for 2014–2020” (hereinafter the Federal Target Program) and the practice of similar domestic and foreign networks. …”
Get full text

Are Academic Libraries Doing Enough to Support the Sustainable Development Goals (SDGs)? A Mixed-Methods Review by Israel Mbekezeli Dabengwa

“…Positive correlations between specific targets imply synergies that libraries can exploit to strengthen their sustainable development roles. …”
Get full text

Adaptation and Implementation of “Care for Child Development" (CCD) Intervention in the Health System in Iran: A Protocol Study by Seifollah Heidarabady, Ali Bahari Gharehgoz, Nasrin Baraheni, Lama Charafeddine, Michela Profeta, Mamak Shariat

“…Providing a comprehensive program to promote the development of children and psychological support for parents of children at risk of developmental delays under three is essential. …”
Get full text

The Impact of Sex Education Towards Moral Development Among Pupils in Kebisoni Sub-County Rukungiri District. by Kamagara, Annet

“…:iplines, an advisory committee builds support for the program, states should also require that school districts do more to facilitate staff development, encouraging parents to become more involved in the development and implementation of sexuality education courses.…”
Get full text

Automatic Optimal Design Method for Minimum Total Resistance Hull Based on Enhanced FFD Method by Shuhui Guo, Baoji Zhang, Zheng Tian, Jie Liu, Hailin Tang

“…To this end, an integrated, fully automated optimization program was developed based on Python, incorporating Enhanced Free-Form Deformation (FFD) technology, scripted CFD numerical evaluation, and the Particle Swarm Optimization (PSO) algorithm. …”
Get full text

Thirty years after the Cairo declaration on population & development: have family planning measurements caught up? by Nour Horanieh, Nour Horanieh, Alice Witt, Marieme Fall, Eloisa Montt-Maray, Lamiah Adamjee, Elizabeth Larson, Thais Gonzalez-Capella, Beniamino Cislaghi, Beniamino Cislaghi

“…IntroductionThe 1994 International Conference on Population Development (ICPD) initiated the transition of family planning (FP) programmes from focusing on population control to promoting human rights and women's empowerment. …”
Get full text

Development of machine learning algorithms to predict viral load suppression among HIV patients in Conakry (Guinea) by Degninou Yehadji, Degninou Yehadji, Geraldine Gray, Carlos Arias Vicente, Petros Isaakidis, Petros Isaakidis, Abdourahimi Diallo, Saa Andre Kamano, Thierno Saidou Diallo

“…This study aims to identify the most predictive variables of VL suppression and develop ML models for PLHIV in Conakry (Guinea).MethodsAnonymized data from HIV patients in eight Conakry health facilities were pre-processed, including variable recoding, record removal, missing value imputation, grouping small categories, creating dummy variables, and oversampling the smallest target class. …”
Get full text

SENP3 Drives Abdominal Aortic Aneurysm Development by Regulating Ferroptosis via De‐SUMOylation of CTH by Long Chen, Zhaohua Cai, Danrui Xiao, Yiping Shi, Qingqing Xiao, Min Liang, Yangjing Jiang, Yijie Huang, Feng Liang, Guo Zhou, Fei Zhuang, Xia Wang, Huanhuan Huo, Liang Fang, Qin Shao, Ben He

“…Mechanistic studies identified Cystathionine Gamma–Lyase (CTH), a critical enzyme involved in hydrogen sulfide production, as a target protein of SENP3 that mediated the exacerbating effects of SENP3 on ferroptosis and inflammatory programs in macrophages. …”
Get full text

Leveraging diverse cell death patterns in osteosarcoma patients and identification of the function of FADS2 in osteosarcoma cells by Guannan Bai, Shaobo Zhao, Lushan Chen, Manli Zhao, Wenhao Chen

“…There is an urgent need to explore novel therapeutic targets to improve the survivorship of OS patients. …”
Get full text