USP21 is involved in the development of chronic hepatitis B by modulating the immune microenvironment by Pengyu Luo, Yuna Tang, Nan Chen, Pei Liu, Jing Wang, Yuchen Fan, Huihui Liu, Kai Wang

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Developing a data‐transfer model for a novel Wildlife‐tracking network by Melanie J. Davis, Sravan Thokala, Xinyu Xing, N. Thompson Hobbs, Daniel P. Walsh, Richard Y. Han, Shivakaht Mishra

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Results of the pedagogical experiment on the development of inclusive competence of teachers of general education organisations by Mirgul Esengulova, Zamira Dzhaparova, Bermet Asanbaeva, Barisa Turdubaeva

“…The purpose of the study was the practical implementation of the developed model of formation of inclusive competence necessary for work in the pedagogical environment. …”
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Efficiency of implementation of state environmental projects to achieve sustainable development of subjects of the Russian Federation by Artem D. Kozlov, Zhanna A. Mingaleva

“…The study found that the instruments of public administration and targeted state financing of various programs within the framework of the national project "Ecology" are effective. …”
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Quality by Design and In Silico Approach in SNEDDS Development: A Comprehensive Formulation Framework by Sani Ega Priani, Taufik Muhammad Fakih, Gofarana Wilar, Anis Yohana Chaerunisaa, Iyan Sopyan

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Development of a Mammalian Cell Line for Stable Production of Anti-PD-1 by Erika Csató-Kovács, Pál Salamon, Szilvia Fikó-Lászlo, Krisztina Kovács, Alice Koka, Mónika András-Korodi, Emőke Antal, Emília Brumă, Brigitta Tőrsők, Szilárd Gudor, Ildikó Miklóssy, Kálmán Csongor Orbán, Csilla Albert, Emese Éva Bálint, Beáta Albert

“…<b>Background/Objectives:</b> Immune checkpoint blockade, particularly targeting the programmed cell death 1 (PD-1) receptor, is a promising strategy in cancer immunotherapy. …”
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Differential Protein-Coding Gene Expression Profile in Patients with Prostate Cancer by Lorena Albarracín-Navas, Maylin Almonte-Becerril, Enmanuel Guerrero, Josue Rivadeneira, Marcelino Telechea-Fernández, Elizabeth Guzmán, Fanny Calderón, María José Hernández-Leal, Tamara Otzen, Carlos Manterola, Galo Duque, Ángela L. Riffo-Campos

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LEGAL SUPPORT OF THE FORMATION OF A MODERN STRATEGIC PLANNING SYSTEM IN RUSSIA by N. M. Mukhetdinova

“…In the recent decades, usage of indicative planning methods has transformed into application of programming methods in steering the economy. The article analyzes the draft law «Strategic planning in the Russian Federation» ready for the 2nd hearing in the State Duma,which creates a legal frameworkfor emergence of an appropriate planning system in Russia.The analysis reviews objectives targeted by the draft law as well as new planning documents including state programs and the long-term budget strategy introduced to ensure the financial realization of the strategic development goals set by the state. …”
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The de novo DNA methyltransferase 3B is a novel epigenetic regulator of MYC in multiple myeloma, representing a promising therapeutic target to counter relapse by Catharina Muylaert, Lien Ann Van Hemelrijck, Arne Van der Vreken, Robbe Heestermans, Hatice Satilmis, Emma Verheye, Elina Alaterre, Catharina Olsen, Nathan De Beule, Kim De Veirman, Eline Menu, Karin Vanderkerken, Jérôme Moreaux, Elke De Bruyne

“…Abstract Background The plasma cell malignancy multiple myeloma (MM) remains incurable due to the inevitable development of drug resistance (DR). Epigenetic modifiers are frequently mutated or deregulated in MM patients, contributing to MM progression and relapse. …”
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Antimicrobial stewardship approach: Prevalence of antimicrobial resistant bacteria at a regional hospital in South Africa by Khin SL Han, Lopez Gustavo, Venesh C Rajkumar, Khine Swe Swe-Han

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Integrating human resource management in urban workforce development: A focus on salary increments by L. Yu, A. Santos

“…Key measures included a mean satisfaction rating of 4.15 for work-life balance initiatives and a mean effectiveness rating of 4.20 for training programs.CONCLUSION: Based on the findings, it is recommended that the company integrate historical narratives into employee training programs to foster organizational pride and loyalty. …”
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Silviculture Promotes Sustainability in <i>Nothofagus antarctica</i> Secondary Forests of Northern Patagonia, Argentina: A Multicriteria Analysis by Matías G. Goldenberg, Claudia Huaylla, Facundo J. Oddi, Juan I. Agüero, Marcos E. Nacif, Guillermo J. Martínez Pastur, Lucas A. Garibaldi

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How can we enhance the performance of medical education development offices in medical universities? A brief overview of implementable actions by Mahla Salajegheh, Parvin Rezaei-Ghazki

“…We hope this perspective stimulates additional conversation and action targeted at boosting educational development in medical institutions.…”
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How far along the future path do individuals recognize the path for stepping on multiple footfall targets? A new evaluation method under virtual reality by Ryotaro Waki, Ryotaro Waki, Kazuyuki Sato, Kazuyuki Sato, Junki Inoue, Junki Inoue, Minoru Yamada, Takahiro Higuchi

“…In this study, we aimed to develop a walking task within a virtual reality (VR) environment, termed the VR multi-target stepping (VR-MTS) task, as a method to evaluate the extent to which individuals can recognize the path ahead while continuously stepping on footfall targets.MethodsAs an initial study for the development of the VR multi-target stepping (VR-MTS) task, we tested a sample of young individuals (8 males and 5 females, aged 26.2 ± 3.7 years). …”
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Understanding the factors influencing the human development index of Asian nations using path analysis by Ronel Geraldizo Dagohoy, Joeteddy Barzaga Bugarin, Leomarich Fortugaliza Casinillo

“…By adopting these targeted strategies, Asian countries can achieve sustainable human development, creating societies where all individuals can lead fulfilling lives.…”
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Implementation of the K-Means Algorithm for Customer Churn Segmentation in Developing Bank Marketing Strategies by Reva Nur Rahmadiana, Dinda Lestarini

“…This study demonstrates that the K-Means algorithm is effective in producing relevant customer segmentation, serving as a valuable foundation for developing more targeted and efficient marketing strategies.…”
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The role of civil society organizations in achieving sustainable development (Nineveh Center for Consulting and Research as a model by Nada Fattah Al-Abachi, Saja Fattah

“… Abstract The research summarizes by studying the role of civil society organizations in achieving sustainable development, especially in areas emerging from conflict and armed conflict, and we have chosen the Nineveh Center for Consultation and Research as a model from several civil society organizations working within the province of Nineveh and trying to get acquainted with its programs and goals and who are the target groups of training and knowing the results Achieved on the ground in a city that was subjected to war and destruction and where people suffered from many types of tragedies and calamities. …”
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A Narrative Inquiry into the Roles of Debate in Developing an Indonesian EFL Teacher’s English Language Proficiency by Arief Eko Priyo Atmojo

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Targeting USP47 enhances the efficacy of KRAS inhibitor in KRASG12C mutated non-small cell lung cancer by controlling deubiquitination of c-Myc by Hyungkyung Shin, SuA Hwang, Jeong Hyun Jeong, Sang Chul Shin, Yeonji Oh, Jinhyeok Kim, Inah Hwang, Eunice EunKyeong Kim, Hyunah Choo, Eun Joo Song

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Phase I study of bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in patients with pretreated biliary tract cancer by Makoto Ueno, Masafumi Ikeda, Do-Youn Oh, Masatoshi Kudo, Christoph Helwig, Changhoon Yoo, Hye Jin Choi, Shunsuke Kondo, Li-Tzong Chen, Motonobu Osada, Isabelle Dussault

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