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Advances in PD-1/PD-L1 pathway inhibitors in the treatment of thyroid cancer: mechanisms and clinical therapeutic perspectives
Published 2025-08-01“…Notably, it summarizes recent clinical developments, such as combination regimens pairing PD-L1 blockade with mutation-targeted therapies, for which the median OS of the targeted combination therapy group was 14.7 months. …”
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Participant Perceptions and Destination Image: Cognitive and Affective Dimensions in Local Sports Contexts
Published 2025-06-01“…These results can inform the development of more targeted and impactful local sports programs that enhance participant’s satisfaction and foster long-term community involvement.…”
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Evaluasi Program Rehabilitasi Sosial Daerah Kumuh terhadap Peningkatan Kualitas Hidup Warga Di Kelurahan Ngagelrejo, Kecamatan Wonokromo Kota Surabaya
Published 2020-06-01“…The results of this evaluation indicate that in general, the Program Implementation was sufficient to meet the criteria targeted at the implementation program. …”
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Memory-promoting function of miR-379-5p attenuates CD8+ T cell exhaustion by targeting immune checkpoints
Published 2025-04-01Get full text
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Evaluating the Impact of a Corporate Social Responsibility Program on Member Trust and Loyalty in a Tennis Club: A Pre- and Post-Intervention Study
Published 2025-04-01“…This study contributes to the literature on CSR in participatory sports by demonstrating the measurable impact of environmental interventions and providing a framework for future CSR program development and evaluation in similar settings.…”
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Leadership competencies for innovability: Bridging theory and practice for sustainable development
Published 2025-01-01“…IMPLICATIONS: Theoretically, the study contributes to the conceptual framework of innovability leadership by identifying critical competencies and suggesting a more integrated approach to leadership development in business education. Practically, the research underscores the importance of developing targeted training programs and assessment tools to cultivate these competencies in future leaders. …”
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ANALISIS PENJAMINAN MUTU FAKULTAS EKONOMI: PENCAPAIAN SASARAN MUTU AKADEMIK DAN KESESUAIAN PROSEDUR AKADEMIK DENGAN STANDAR MUTU ISO 9001:2008
Published 2016-02-01“…The result of the research gave empirical support that: (1) the achivement of academic quality target on students and graduetes standard was very good at the Accounting Departments; it was good at Management; it was good enough at Economics Education and Development Ecoonomics Departments. (2) the achivement of academic quality target on Human Resources standard was very good at the Accounting Department, it was very good at Economics Education Department, and it was good enough at the Development Economics and Management Departments. (3) the achivement of academic quality target in curriculum, learning process, academic situation standard was very good at the Accounting, Management, Development Economics and Economics Education Departments, (4) the achivement quality target on facilities. …”
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Internet addiction and network identity: features of development in student youth
Published 2024-12-01Get full text
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Developmental stages of the Pekin duck (Anas platyrhynchos f. domestica) and the Mulard duck in artificial incubation
Published 2025-08-01“…For this reason, the incubation program needs to be targeted individually for each with these breeds.…”
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Role of PD-1/PD-L1 signaling axis in oncogenesis and its targeting by bioactive natural compounds for cancer immunotherapy
Published 2024-12-01“…A range of monoclonal antibodies, including avelumab, atezolizumab, camrelizumab, dostarlimab, durvalumab, sinitilimab, toripalimab, and zimberelimab, have been developed for targeting the interaction between PD-1 and PD-L1. …”
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Analysis of factors influencing contact in the 686 Program for patients with a first-time diagnosis of severe mental disorders in Hainan Province from 2018 to 2022
Published 2025-03-01“…Factors influencing the engagement in 686 Program among individuals with severe mental disorders remain underexplored in current research.This study aims to understand the barriers and facilitators to program contact, offers implications for the development of targeted interventions for people with severe mental disorders, enabling the creation of more tailored and impactful strategies to enhance the 686 Program’s effectiveness and reach. …”
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Myopia development: multifactorial interplay, molecular mechanisms and possible strategies
Published 2025-08-01“…For CRISPR-based approaches, critical challenges include mitigating off-target editing risks and developing safe, efficient in vivo delivery systems to the relevant ocular tissues. …”
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Entrustable professional activities in Finnish radiology training: a national survey
Published 2025-06-01Get full text
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THE WESTERN EXPERIENCE IN FINANCIAL-ECONOMIC DEVELOPMENT MECHANISMS OF INNOVATION CLUSTERS
Published 2015-03-01“…The western experience of cluster approachinfinancial-economic developmentmechanisms is considered for better understanding of Russian economic development. Among them we highlight: direct financing, reduction in tax, legislative remedies of intellectual property, providing loans and target donations, as well as the creating the funds of implementing the innovations. …”
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In Silico Pharmacological Prediction of Substituted Aminonitriles
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