Pre-Breeding Considerations for the Development of Replacement Beef Heifers by Pedro L. P. Fontes, Nicky Oosthuizen, Carla D. Stanford, G. Cliff Lamb

“…To ensure satisfactory performance during the first breeding season, replacement heifers must be subjected to an adequate development program. This 3-page fact sheet covers age at puberty, nutrition, target body weight gain, pelvic area measurements, reproductive tract score, and herd health. …”
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Pre-Breeding Considerations for the Development of Replacement Beef Heifers by Pedro L. P. Fontes, Nicky Oosthuizen, Carla D. Stanford, G. Cliff Lamb

“…To ensure satisfactory performance during the first breeding season, replacement heifers must be subjected to an adequate development program. This 3-page fact sheet covers age at puberty, nutrition, target body weight gain, pelvic area measurements, reproductive tract score, and herd health. …”
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Pre-Breeding Considerations for the Development of Replacement Beef Heifers by Pedro L. P. Fontes, Nicky Oosthuizen, Carla D. Stanford, G. Cliff Lamb

“…To ensure satisfactory performance during the first breeding season, replacement heifers must be subjected to an adequate development program. This 3-page fact sheet covers age at puberty, nutrition, target body weight gain, pelvic area measurements, reproductive tract score, and herd health. …”
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The Alzheimer's Prevention Initiative Generation Program: Study design of two randomized controlled trials for individuals at risk for clinical onset of Alzheimer's disease by Cristina Lopez Lopez, Pierre N. Tariot, Angelika Caputo, Jessica B. Langbaum, Fonda Liu, Marie‐Emmanuelle Riviere, Carolyn Langlois, Marie‐Laure Rouzade‐Dominguez, Martin Zalesak, Suzanne Hendrix, Ronald G. Thomas, Vissia Viglietta, Rob Lenz, J. Michael Ryan, Ana Graf, Eric M. Reiman

“…Under the umbrella of the Alzheimer's Prevention Initiative Generation Program, therapies targeting Aβ, including CNP520 (umibecestat), a β‐site‐amyloid precursor protein cleaving enzyme‐1 (BACE‐1) inhibitor, and CAD106, an active Aβ immunotherapy, are in clinical development in preclinical AD. …”
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Online Education on the Development of Functional Foods and the Nutrients Encapsulation by Lanny Sapei, Natalia Suseno, Hendrik Gunawan

“…Due to the COVID-19 pandemic, society is becoming more aware of maintaining health by consuming healthy and nutritious foods. Therefore, the target of this educational webinar program was educated individuals in the education sector, and they were expected to influence their surrounding communities to adopt healthy eating patterns through the consumption of functional foods. …”
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Using Andersen's behavioral model of health care utilization in a decentralized program to examine the use of antenatal care in rural western Ethiopia. by Habtamu Tolera, Tegegne Gebre-Egziabher, Helmut Kloos

“…<h4>Conclusions</h4>Number of children, home visits, gainful activities, monthly income, high fever, and decentralized administrative kebele were strongly linked with recommended ANC schedule. The need for a program intervention aimed at meeting WHO recommendations for ANC visits include economizing birth size and spacing; improving home attendance by HEWs, knowledge of pregnancy complications and benefits of minimum ANC visits, local socio-economic development measures targeting poor women/households; further decentralization of health system improving proximity to ANC in rural western Ethiopia.…”
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Preliminary Study on Enhancing Literacy Skills Through Intervention Targeting Inhibitory Control, Cognitive Flexibility, Working Memory, and Attentional Control by Marta Castillo-Segura, Miguel Á. Carbonero-Martín, Luis J. Martín-Antón

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Intervention strategies for type 2 diabetes prevention in high-income countries targeting low socioeconomic groups: a scoping review by J. Thylefors, M. Annersten Gershater, E. Mangrio, S. Zdravkovic

“…Populations with lower socioeconomic status have a higher prevalence and poorer outcomes, making preventive interventions targeting these groups increasingly important.ObjectiveTo investigate the types of interventions that have been tested and reported regarding the prevention of type 2 diabetes targeting low socioeconomic populations and are applicable in a high-income country.MethodsBased on a systematic search strategy developed using the People, Concept, and Context model, the databases CINAHL, PubMed, and Web of Science were searched in January 2024 and updated in December 2024, and EMBASE was searched in May 2025. …”
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Study of target INR achievement, incidence of hemorrhagic complications and affecting factors after during warfarin treatment in western area of China by Rui Shi, Wei Wei, Yanbiao Yang, Shouyuan Yang, Liping Yan, Zongjie Zhu

“…Statistical analysis employed Pearson chi-square tests to evaluate associations between clinical variables and primary outcomes: achievement of target INR ranges (2.0–3.0 for most indications; 1.8–2.5 for mechanical valves) and development of hemorrhagic complications. …”
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The Method of Viral Mimicry in Oncology and Prospects for its Improvement by R. N. Mustafin

“…Tumor cells produce CTLA4 (CTLA4 — cytotoxic T-lymphocyte protein 4) and PD-1 (programmed cell death) checkpoints that inhibit the activity of T-lymphocytes and their production of antitumor cytokines. …”
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Improving arterial hypertension control in patients with high cardiovascular event risk: main stages of Russian Research and Clinical Program ARGUS-2 by A. I. Martynov, V. S. Moiseev, R. G. Oganov, Zh. D. Kobalava, Yu. V. Kotovskaya, E. G. Starostina

“…Principal results of the Russian Research and Clinical Program ARGUS. In this patient group, arterial hypertension (AH) control is very low, as well as diuretic prescription rate. …”
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Programmed Cell Death Protein 10 (PDCD10) Regulates Vesicle Trafficking and Contributes to the Progression of Clear Cell Renal Cell Carcinoma by Rui Wang, Tianyu Lin, Yi Liu, Hao Wang, Xinyu Liu, Yihan Dong, Jiaxin Li, Huamao Jiang, Ruibing Chen, Yong Wang, Dan Yue

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Importance of pattern recognition for later symbolic arithmetic: piloting a novel online training program for children in their first year of primary education by Kurt Winkler, Martin Schöfl, Liane Kaufmann, Christoph Weber

“…The training app “LORE” specifically targets and cultivates pattern recognition skills from the beginning of formal schooling. …”
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mRNA and protein expression of programmed cell death-ligand-1 on canine mammary gland tumour in dogs of Chiang Mai, Thailand by Wanwisa Srisawat, Pongpisid Koonyosying, Anucha Muenthaisong, Kanokwan Sangkakam, Thanya Varinrak, Amarin Rittipornlertrak, Boondarika Nambooppha, Nisachon Apinda, Nattawooti Sthitmatee

“…The findings strongly support the potential for developing effective immunotherapy methods targeting the PD-1/PD-L1 pathway for advanced CMTs in the future. …”
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Implementation of a Cost and Variation Reduction Program for Hemostasis Products at a Large Academic Medical Center: A Multi-Stakeholder Perspective by Shah T, Brethauer S, Danker III WA, Doshi I, O'Hara M, Silber A, Vasileff WK

“…Thus, we sought to evaluate hospital stakeholder satisfaction with conversion to a sole supplier for hemostasis products, in addition to economic and clinical impacts, to help develop best practices for implementation.Methods: This cross-sectional study assessed satisfaction with converting to a sole supplier for hemostasis products at a large US academic medical center using qualitative interviews and quantitative surveys with clinical and non-clinical stakeholders, on the decision-making process, conversion, and vendor-supported hemostasis optimization program (HOP) post-implementation (February 2022–May 2022). …”
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The challenges and opportunities of applying tumour mutational burden analysis to precision cancer medicine by Attia M. Elbehi

“…Initially, treatment was administered to patients on the basis of expression levels of one of the targets of ICI therapy, programmed cell death ligand 1. …”
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The role of health literacy in intervention studies targeting children living with overweight or obesity and their parents—a systematic mixed methods review by Heidi Holmen, Heidi Holmen, Tone Nygaard Flølo, Tone Nygaard Flølo, Christine Tørris, Astrid Torbjørnsen, Kari Almendingen, Kirsti Riiser, Kirsti Riiser

“…Thus, there is a need to summarize the effects of and experiences with interventions that include health literacy components to guide the development of effective, future weight-related interventions.AimThis review aims to identify how health literacy is integrated into studies of interventions targeting children with excess weight or obesity and/or their parents and to appraise the identified literature.MethodsWe conducted a systematic mixed methods review, with searches in Medline, CINAHL, Cochrane, EMBASE, ERIC, PsycINFO, and Web of Science. …”
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EIF2AK2 protein targeted activation of AIM2-mediated PANoptosis promotes sepsis-induced acute kidney injury by Siwei Wei, Lei Wu, Zhen Xiang, Xiaoxiao Yang, Dongjie Pei, Liubing Jiang, Zhen Du

“…PANoptosis refers to a type of inflammatory programmed cell death that exhibits key characteristics of apoptosis, necroptosis, and pyroptosis. …”
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Molecular heterogeneity of CD30+ peripheral T-cell lymphoma with prognostic significance and therapeutic implications: a retrospective multi-centre studyResearch in context by Yu-Jia Huo, Shu Cheng, Hong-Mei Yi, Ting Niu, Lei Fan, Guo-Hui Cui, Fu-Ling Zhou, Xian-Min Song, Fei Li, Ou Bai, Xiao-Jing Yan, Jun Shi, Ming-Ci Cai, Yao-Hui Huang, Lei Dong, Jie Xiong, Song Hu, Yu-Ran Qiu, Yan Zhao, Peng-Peng Xu, Li Wang, Min Lu, Hong-Mei Jing, Wei-Li Zhao

“…Funding: This study was supported by National Key R&D Program of China, National Natural Science Foundation of China, Clinical Research Plan of Shanghai Hospital Development Centre, Shanghai Clinical Research Centre for Cell Therapy, Shanghai Municipal Health Commission, and China Postdoctoral Science Foundation.…”
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Dietary ginger (Zingiber officinale) enhances performance traits, biochemical and haematological indices of Turkey targeting mRNA gene expression by Eman A. Manaa, Mervat A. Abdel-Latif, Samya E. Ibraheim, Abdelaziz M. Sakr, Hanaa M. Ghanem, Rania M. Waheed, Ghadeer M. Albadrani, Mohamed M. Abdel-Daim, Amr El Zawily, Basant M. Shafik

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