Sources and Forms of Financing of Innovative Activities in Germany by Elmira Mekhdyatovna Khayretdinova, Vera Andreevna Zubenko

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Algorithm for Recognition of Small Air Targets by Trajectory Features in Passive Bistatic Radar by Dao Van Luc, A. A. Konovalov, Le Minh Hoang

“…Aim. Development of an algorithm for recognizing small air targets by trajectory features based on machine learning. …”
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Alterations in mitochondrial base editors enhance targeted editing efficiency for mouse model generation by Seongho Hong, Sol Pin Kim, Sanghun Kim, Soo Kyung Kang, Sungmo Jung, Yeji Oh, Seung Hee Choi, Su Bin Lee, Hou Cha, Jieun Kim, Jiyoung Bae, Jiyoon Park, Kyoungmi Kim, Chang Geun Choi, Soo-Ji Park, Do Hyun Kim, Lark Kyun Kim, Je Kyung Seong, Hyunji Lee

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An Android-Based Game for Improving Students’ English Literacy in Targeted School of Kampus Mengajar by Yusniarsi Primasari, Supriyono, Yayuk Widyastuti, Hesty Puspita Sari

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Unravelling inflammation-driven mechanisms in hepatocellular carcinoma: therapeutic targets and potential interventions by Dhrubajyoti Sen, Sonia Bisht, Sangeetha Gupta

“…This study concentrates on important inflammatory targets that are essential for regulating immune responses in the tumor microenvironment, such as the NOD-like receptor protein 3 (NLRP3) inflammasome, programmed cell death protein (PD-L1), stimulator of interferon genes 1 (STING1), high mobility group box 1 (HMGB1), pentraxin 1, and vascular cell adhesion molecule 1 (VCAM1). …”
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Using Crawlers for Targeted Data Extraction from a Local Multi-File Database by Alexandru ANGHELESCU, Ciprian-Viorel STUPINEAN, Ariana-Anamaria CORDOȘ

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An optimized integrin α6-targeted peptide capable of delivering toxins for melanoma treatment by Zheng Zhao, Zi-Qian Li, Ying-Bin Huang, Meng-meng Liu, Fei Cao, Guo-Long Bu, Peng-Fei Xu, Qi Fang, Zhu-Long Hu, Di Wu, Guo-Kai Feng, Xue-Kui Liu

“…Cell-penetrating peptides (CPPs) with the ability to selectively enter cancer cells, with sufficient stability and increased endosomal escape mechanisms, can provide a new and improved delivery strategy for therapeutic agents for treating cancer. Methods We developed a new combination strategy for the synthesis of penetrating peptides functionalized with targeting of integrin α6. …”
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Targeting Policy for Obesity Prevention: Identifying the Critical Age for Weight Gain in Women by Trevor J. B. Dummer, Sara F. L. Kirk, Tarra L. Penney, Linda Dodds, Louise Parker

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Target Bioconjugation of Protein Through Chemical, Molecular Dynamics, and Artificial Intelligence Approaches by Sk Jahir Abbas, Sabina Yesmin, Sandeepa K. Vittala, Nayim Sepay, Fangfang Xia, Sk Imran Ali, Wei-Chun Chang, Yao-Ching Hung, Wen-Lung Ma

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Non-coding RNAs: emerging biomarkers and therapeutic targets in cancer and inflammatory diseases by Basma Hossam Abdelmonem, Basma Hossam Abdelmonem, Lereen T. Kamal, Lilian Waheed Wardy, Lilian Waheed Wardy, Manon Ragheb, Manon Ragheb, Mireille M. Hanna, Mohamed Elsharkawy, Anwar Abdelnaser

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Bis(7)-harmine derivatives as potential multi-target anti-Alzheimer agents by Hongtao Du, Hongtao Du, Hongtao Du, Fang Ma, Fang Ma, Yuanyuan Cao, Miaoyan Bai, Xinyi Gao, Ziyi Yang, Yang Xu, Yan Yan, Yan Yan

“…IntroductionThe multi-targeted ligands (MTDL) strategy has been recognized as a promising Approach for the development of effective treatments against Alzheimer’s disease (AD), due to the presence of multiple pathological mechanisms in AD. …”
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Unlocking the power of probiotics, postbiotics: targeting apoptosis for the treatment and prevention of digestive diseases by Qiuyan Xie, Ji Liu, Ping Yu, Ting Qiu, Shanyu Jiang, Renqiang Yu

“…Digestive diseases are becoming an increasingly serious health burden, creating an urgent need to develop more effective treatment strategies. Probiotics and postbiotics have been extensively studied for their potential to prevent and treat digestive diseases. …”
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Food-derived compounds targeting ferroptosis for cancer therapy: from effects to mechanisms by Jin-Wei Zhao, Wei-Yi Zhao, Zhongyang Yu, Zhongyang Yu

“…Finally, the challenges and opportunities of developing dietary compounds as ferroptosis inducers are discussed, focusing on the discovery of new targets, enhancing selectivity, as well as reducing toxicity and the recurrence of side effects. …”
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THE ANALYSIS OF EXPERIENCE OF DEVELOPED COUNTRIES IN THE APPLIANCE OF STATE SUPPORT IN THE SYSTEM OF MANAGEMENT AND AGRICULTURAL DEVELOPMENT by G. Fyliuk, O. Pimenova

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Contribution of Youth Livelihood Program (YLP) Towards Agriculture in Nyarusiza Sub-County Kisoro District. by Ndirahisha, Brian

“…Addressing these challenges through targeted strategies can enhance the program's effectiveness, leading to greater agricultural productivity, economic growth, and youth empowerment. …”
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Programmed cell death-related ABI1 is a critical mediator of abdominal aortic aneurysm by Han Wang, Zhihai Xu, Jing Guo, Lei Li, Yu Tian, Shengjie Fu

“…The findings suggest that ABI1 may represent a promising therapeutic target for the prevention and treatment of AAA. Further research is warranted to fully understand the role of ABI1 in AAA and to develop targeted therapies based on this promising target.…”
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Faculty Perceptions on the Roles of Mentoring, Advising, and Coaching in an Anesthesiology Residency Program: Mixed Methods Study by Sydney Nykiel-Bailey, Kathryn Burrows, Bianca E Szafarowicz, Rachel Moquin

“…ConclusionsImplementing structured mentoring, advising, and coaching can profoundly impact resident education but requires role clarity, protected time, culture change, leadership buy-in, and faculty development. Targeted training and operational investments could enable programs to actualize immense benefits from high-quality resident support modalities. …”
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Regulation of the developmental programs in Toxoplasma by a novel SNF2L-containing chromatin remodeling complex by Yuchao Zhu, Bolin Fan, Hao Xu, Yazhou Li, Xiaohan Liang, Lilan Xue, Liting Wei, Fuqiang Fan, Xin Zhang, Yukun Chen, Shanshan Qian, Bang Shen

“…Here, we screen putative chromatin remodeling proteins in T. gondii and find that a novel complex containing an evolutionarily conserved ATPase SNF2L is critical for programming the parasite’s development. This complex contains four core proteins and conditional depletion of three of them leads to similar expression changes of developmentally regulated genes, including increased transcription of genes involved in sexual commitment and development. …”
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Workplace health promotion program: An integrated intervention to promote well-being among healthcare workers by Silvia Vivarelli, Concettina Fenga

“…Overall, the suggested protocol is expected to inform targeted strategies aimed at promoting health, improving workplace safety, and guiding occupational policy development. …”
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Inter-relationship between testicular dysgenesis and Leydig cell function in the masculinization programming window in the rat. by Sander van den Driesche, Petros Kolovos, Sophie Platts, Amanda J Drake, Richard M Sharpe

“…Studies in rats exposed in utero to di(n-butyl) phthalate (DBP) have strongly supported the TDS concept, but so far no direct evidence has been produced that links dysgenesis per se to somatic cell dysfunction, in particular to androgen production/action during the 'masculinization programming window' (MPW; e15.5-e18.5). Normal reproductive tract development and anogenital distance (AGD) are programmed within the MPW, and TDS disorders arise because of deficiencies in this programming. …”
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