Suggested Topics within your search.
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4021
Study of the Elemental Composition of Gadolinium–Aluminum Garnets—Obtaining Predictable Optical Properties
Published 2024-12-01“…For the first time, inductively coupled plasma mass spectrometry (ICP-MS) was developed for determining the target elemental composition of gadolinium–aluminum garnets with the varying composition Gd<sub>3–x</sub>Ce<sub>x</sub>Sc<sub>y</sub>Al<sub>5–y</sub>O<sub>12</sub>, where x = 0.01–0.16 and y = 0.25–1.75. …”
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4022
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4023
Anti-TGF-β/PD-L1 bispecific antibody promotes T cell infiltration and exhibits enhanced antitumor activity in triple-negative breast cancer
Published 2022-12-01“…In this work, we constructed a bispecific antibody targeting TGF-β and human PD-L1 (termed BiTP) and explored the antitumor effect of BiTP in TNBC.Methods BiTP was developed using Check-BODYTM bispecific platform. …”
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4024
Efficacy and safety of immunotherapy in cervical cancer: a review of advances in immune-related therapy for cervical cancer
Published 2025-03-01“…Abstract Purpose Immunotherapy is emerging as a promising approach for cervical cancer treatment, with new targets and drugs continuously being developed. In response to the wide range of immunotherapies currently available, this article aims to review and sort the immunotherapy for cervical cancer and the advancements in assessing effectiveness and prognosis. …”
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4025
An automated A-value measurement tool for accurate cochlear duct length estimation
Published 2018-01-01Get full text
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4026
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4027
Optimized lentiviral backbone induces robust and diverse T cell immunity against neoantigens to counteract tumor heterogeneity
Published 2025-07-01“…Incorporating proteasome-targeting sequences and 4-alanine spacers between neoepitopes enhanced responses to both dominant and subdominant neoepitopes. …”
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4028
Effect of prolonged cooking on pro-vitamin A levels of biofortified East African highland bananas
Published 2025-12-01Get full text
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4029
Harnessing lipid metabolism modulation for improved immunotherapy outcomes in lung adenocarcinoma
Published 2024-07-01“…Furthermore, the lipid metabolism score (LMS) system was constructed, and based on the LMS system, we further performed screening for potential agents targeting lipid metabolism. The mechanism of MK1775 was further validated using RNA sequencing, co-culture technology, and in vivo experiments.Results We developed an LSM system and identified a potential sensitizing agent, MK1775, which targets lipid metabolism and enhances the effects of anti-PD-1 treatment. …”
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4030
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4031
Unlocking tiny titans: 360 view of the quantum dots nanotechnology for dental applications
Published 2025-03-01Get full text
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4032
Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses
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4033
A Protozoology and Parasitological Techniques Brochure
Published 2012-06-01“…The theoretical contents listed in this brochure were developed in response to the contents included in the program for biological agents incorporated to the new curriculum of Bachelors in Health Technology, Bachelors in Clinical Bio-analysis and the rest of the studies in the field of Medical Sciences.…”
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4034
Stem Cell Niche Dynamics: From Homeostasis to Carcinogenesis
Published 2012-01-01Get full text
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4035
Clobetasol and Halcinonide Act as Smoothened Agonists to Promote Myelin Gene Expression and RxRγ Receptor Activation.
Published 2015-01-01“…One of the causes of permanent disability in chronic multiple sclerosis patients is the inability of oligodendrocyte progenitor cells (OPCs) to terminate their maturation program at lesions. To identify key regulators of myelin gene expression acting at the last stages of OPC maturation we developed a drug repositioning strategy based on the mouse immortalized oligodendrocyte (OL) cell line Oli-neu brought to the premyelination stage by stably expressing a key factor regulating the last stages of OL maturation. …”
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4036
Expanding the Role of FurA as Essential Global Regulator in Cyanobacteria.
Published 2016-01-01“…The results of such approaches led us to identify 15 novel direct iron-dependent transcriptional targets belonging to different functional categories including detoxification and defences against oxidative stress, phycobilisome degradation, chlorophyll catabolism and programmed cell death, light sensing and response, heterocyst differentiation, exopolysaccharide biosynthesis, among others. …”
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4037
Prognostic value of disulfidptosis-associated genes in gastric cancer: a comprehensive analysis
Published 2025-03-01“…FRMD6-AS emerged as a potential target for gastric cancer treatment.ConclusionsThis study developed a novel prognostic model for gastric cancer using DRLs, identifying two key signaling axes related to prognosis. …”
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4038
Reframing conservation audiences from individuals to social beings
Published 2024-11-01Get full text
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4039
In Silico Analysis of miRNA-mRNA Binding Sites in <i>Arabidopsis thaliana</i> as a Model for Drought-Tolerant Plants
Published 2025-06-01“…Using the MirTarget program, 274 miRNAs and 48,143 gene transcripts were analyzed to predict high-confidence miRNA–mRNA interactions based on binding free energies (−79 to −129 kJ/mole). …”
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4040
Improving company communication activity amidst the СOVID-19 restrictions
Published 2021-06-01“…The findings allowed developing the suggestions for forming a communication program of Like Center LLC under quarantine the COVID-19 restrictions. …”
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