Additive interaction of conjoint tobacco smoking and heavy drinking on hypertension prevalence in rural Uganda: a community-based cross-sectional study by Paineto Masengere, Nynke Halbesma, Rawlance Ndejjo, Bonny Enock Balugaba, Rhoda K. Wanyenze, Fred Nuwaha, Hilde Bastiaens, Geofrey Musinguzi

“…All analyses were performed via R programming software version 4.2.3. Results HBP was prevalent in 23% of the participants. …”
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SGSM1 as a pan-cancer biomarker: multi-omics insights into immune regulation, prognostic value, and therapeutic implications by Dali Wu, Guanghui Zhong, Yufeng Liu, Cuilian Li, Lingfei Yan, Yang Luo, Qing Li, Dawei Liu, Tao Wang

“…SGSM1 may be implicated in the tumor immune microenvironment, which holds promise as a putative novel treatment target for cancer.…”
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Baseline predictors for 28-day COVID-19 severity and mortality among hospitalized patients: results from the IMPACC study by Jintong Hou, Benjamin Haslund-Gourley, Joann Diray-Arce, Annmarie Hoch, Nadine Rouphael, Patrice M. Becker, Alison D. Augustine, Al Ozonoff, Leying Guan, Steven H. Kleinstein, Bjoern Peters, Elaine Reed, Matt Altman, Charles R. Langelier, Holden Maecker, Seunghee Kim, Ruth R. Montgomery, Florian Krammer, Michael Wilson, Walter Eckalbar, Steven E. Bosinger, Ofer Levy, Hanno Steen, Lindsey B. Rosen, Lindsey R. Baden, Esther Melamed, Lauren I. R. Ehrlich, Grace A. McComsey, Rafick P. Sekaly, Joanna Schaenman, Albert C. Shaw, David A. Hafler, David B. Corry, Farrah Kheradmand, Mark A. Atkinson, Scott C. Brakenridge, Nelson I. Agudelo Higuita, Jordan P. Metcalf, Catherine L. Hough, William B. Messer, Bali Pulendran, Kari C. Nadeau, Mark M. Davis, Ana Fernandez Sesma, Viviana Simon, Monica Kraft, Chris Bime, Carolyn S. Calfee, David J. Erle, IMPACC Network, Lucy F. Robinson, Charles B. Cairns, Elias K. Haddad, Mary Ann Comunale

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Phase I study of ribociclib (CDK4/6 inhibitor) with spartalizumab (PD-1 inhibitor) with and without fulvestrant in metastatic hormone receptor-positive breast cancer or advanced ov... by Sara M Tolaney, Tianyu Li, Elizabeth A Mittendorf, Geoffrey I Shapiro, Stephanie K Dougan, Nabihah Tayob, Joyce F Liu, Khanh Do, Heather Parsons, Molly DiLullo, Eileen Wrabel, Lestat R Ali, Ana C Garrido-Castro, Noah Graham, Christina Herold, Jennifer Desrosiers, Shom Goel, Amy J Williams

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Regulatory effects of Ishige okamurae extract and Diphlorethohydroxycarmalol on skin barrier function by Seon Gyeong Bak, Hyung Jin Lim, Yeong-Seon Won, Sang-Ik Park, Sun Hee Cheong, Seung Jae Lee

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Genome-Wide Identification and Expression Profiling of Glycosidases, Lipases, and Proteases from Invasive Asian Palm Weevil, <i>Rhynchophorus ferrugineus</i> by Nazmi Harith-Fadzilah, Mohammad Nihad, Mohammed Ali AlSaleh, Abdulqader Yaslam Bazeyad, Subash-Babu Pandurangan, Kashif Munawar, Arya Vidyawan, Hattan A. Alharbi, Jernej Jakše, Arnab Pain, Binu Antony

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The Monthly Cycling of Food Insecurity in Latinas at Risk for Diabetes: Methods, Retention, and Sample Characteristics for a Microlongitudinal Design by Angela Bermúdez-Millán, Rafael Pérez-Escamilla, Sofia Segura-Pérez, James Grady, Richard S Feinn VI, Hanako Agresta, Dean Kim, Julie Ann Wagner

“…Just under half (41/87, ) spoke Spanish only, 69% (60/87) had no formal schooling, and 31% (27/87) had less than eighth ConclusionsThis study demonstrated how FI cycles over the month and whether and to what degree the cycling itself is related to the risk for T2D development, as well as the evidence for some putative mechanisms of this association that can serve as future intervention targets including SNAP disbursement schedules.…”
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Regulatory effects of specialized metabolites from Dendrobium albosanguineum on lipid metabolism and adipocyte differentiation by Jittima Wuttiin, Poomraphie Nuntawong, Hnin Ei Ei Khine, Rungroch Sungthong, Tharita Kitisripanya, May Thazin Thant, Chatchai Chaotham, Wanwimon Mekboonsonglarp, Kittisak Likhitwitayawuid, Boonchoo Sritularak

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Readiness and Acceptance of Health Providers using Clinical Decision Support System at Probolinggo Primary Healthcare Centers by Rokayah Rokayah, Riza Alfian, Yunita Nita, Hanni Prihhastuti Puspitasari

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Substituted 1,4-naphthoquinones for potential anticancer therapeutics: In vitro cytotoxic effects and QSAR-guided design of new analogs by Veda Prachayasittikul, Prasit Mandi, Ratchanok Pingaew, Supaluk Prachayasittikul, Somsak Ruchirawat, Virapong Prachayasittikul

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Virtual library docking for cannabinoid-1 receptor agonists with reduced side effects by Tia A. Tummino, Christos Iliopoulos-Tsoutsouvas, Joao M. Braz, Evan S. O’Brien, Reed M. Stein, Veronica Craik, Ngan K. Tran, Suthakar Ganapathy, Fangyu Liu, Yuki Shiimura, Fei Tong, Thanh C. Ho, Dmytro S. Radchenko, Yurii S. Moroz, Sian Rodriguez Rosado, Karnika Bhardwaj, Jorge Benitez, Yongfeng Liu, Herthana Kandasamy, Claire Normand, Meriem Semache, Laurent Sabbagh, Isabella Glenn, John J. Irwin, Kaavya Krishna Kumar, Alexandros Makriyannis, Allan I. Basbaum, Brian K. Shoichet

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Peptide-directed interference of PD-1/PD-L1 binding increases B lymphocyte function after infectious bursal disease viral infection by Qiuyu Zhang, Guopeng Sun, Feng Yue, Zhike Liu, Peng Li, Yanping Zhu, Yangzhao Zhu, Ruiyan Niu, Zilong Sun, Xuannian Wang, Gaiping Zhang

“…ABSTRACT: Programmed cell death protein 1 (PD-1)/PD-1 ligand 1 (PD-L1) binding contributes to immune evasion mechanisms responsible for B lymphocyte exhaustion and apoptosis. …”
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Impact of life adversity and gene expression on psychiatric symptoms in children and adolescents: findings from the Brazilian high risk cohort study by Vanessa Kiyomi Ota, Vanessa Kiyomi Ota, Vanessa Kiyomi Ota, Vanessa Kiyomi Ota, Adrielle Martins Oliveira, Adrielle Martins Oliveira, Adrielle Martins Oliveira, Amanda Victória Gomes Bugiga, Amanda Victória Gomes Bugiga, Amanda Victória Gomes Bugiga, Helena B. Conceição, Pedro Alexandre Favoretto Galante, Paula Fontes Asprino, Julia Luiza Schäfer, Julia Luiza Schäfer, Mauricio Scopel Hoffmann, Mauricio Scopel Hoffmann, Mauricio Scopel Hoffmann, Mauricio Scopel Hoffmann, Mauricio Scopel Hoffmann, Rodrigo Bressan, Rodrigo Bressan, Rodrigo Bressan, Elisa Brietzke, Gisele Gus Manfro, Gisele Gus Manfro, Rodrigo Grassi-Oliveira, Ary Gadelha, Ary Gadelha, Luis Augusto Rohde, Luis Augusto Rohde, Luis Augusto Rohde, Luis Augusto Rohde, Euripedes Constantino Miguel, Euripedes Constantino Miguel, Pedro Mario Pan, Pedro Mario Pan, Pedro Mario Pan, Marcos Leite Santoro, Marcos Leite Santoro, Marcos Leite Santoro, Giovanni Abrahao Salum, Giovanni Abrahao Salum, Giovanni Abrahao Salum, Carolina Muniz Carvalho, Carolina Muniz Carvalho, Carolina Muniz Carvalho, Sintia Iole Belangero, Sintia Iole Belangero, Sintia Iole Belangero, Sintia Iole Belangero

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Insights into miRNAs of the Stingless Bee <i>Melipona quadrifasciata</i> by Dalliane Oliveira Soares, Lucas Yago Melo Ferreira, Gabriel Victor Pina Rodrigues, João Pedro Nunes Santos, Ícaro Santos Lopes, Lucas Barbosa de Amorim Conceição, Tatyana Chagas Moura, Isaque João da Silva de Faria, Roenick Proveti Olmo, Weyder Cristiano Santana, Marco Antônio Costa, Eric Roberto Guimarães Rocha Aguiar

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Molecular characterization of VP1 gene during the foot and mouth disease virus outbreak in East Java, Indonesia, in 2022 by Zayyin Dinana, Suwarno Suwarno, Imam Mustofa, Jola Rahmahani, Kusnoto Kusnoto, Aussie Tahta Maharani, Anisa Lailatul Fitria, Adiana Mutamsari Witaningrum, Firdausy Kurnia Maulana, Nur Saidah Said, Deka Uli Fahrodi, Fedik Abdul Rantam

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Circular RNA circPHLPP2 promotes tumor growth and anti-PD-1 resistance through binding ILF3 to regulate IL36γ transcription in colorectal cancer by Yan Hu, Ze-Rong Cai, Ren-Ze Huang, De-Shen Wang, Huai-Qiang Ju, Dong-Liang Chen

“…Abstract Background Most Colorectal Cancer (CRC) patients exhibit limited responsiveness to anti-programmed cell death protein 1 (PD-1) therapy, with the underlying mechanisms remaining elusive. …”
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Natural and Designed Cyclic Peptides as Potential Antiviral Drugs to Combat Future Coronavirus Outbreaks by Hilarie Uwamahoro, Willard E. Collier, Toufic O. Nashar, Jesse M. Jaynes, Desmond G. Mortley, Cheryl G. Davis, Getrude G. Kanyairita, Eslam F. Abdelazim, Jean Francois Regis Igiramaboko, Concorde Habineza, Devotha Tumushimiyimana, Umuraza Noella Rutayisire, Yasmin A. Davis, Kamora L. Renard

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Genome-wide association study −Driven drug repositioning for the treatment of insomnia by Rahmat Dani Satria, Wirawan Adikusuma, Usi Sukorini, Devy Eka Avitasari, Indra Sari Kusuma Harahap, Mohammad Hendra Setia Lesmana, Lalu Muhammad Irham, Nur Imma Fatimah Harahap, Pranindya Rinastiti, Donytra Arby Wardhana, Richardus Wisnandito Prabasaktya, Chiou-Feng Lin, Aprilia Paramitasari, Andrian Fajar Kusumadewi

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Sex-specific NLRP3 activation in neutrophils promotes neutrophil recruitment and NETosis in the murine model of diffuse alveolar hemorrhage by Pierre-André Jarrot, Pierre-André Jarrot, Jiyoun Kim, Jiyoun Kim, William Chan, William Chan, Lukas Heger, Lukas Heger, Lukas Heger, Nicolas Schommer, Nicolas Schommer, Nicolas Schommer, Pierre Cunin, Camila M. S. Silva, Camila M. S. Silva, Stéphane Robert, Peter A. Nigrovic, Bruce Ewenstein, Bruce Ewenstein, Denisa D. Wagner, Denisa D. Wagner

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Pain Hypersensitivity and Increased Urinary Tetrahydrobiopterin Levels in Mice Submitted to High-Fat Diet by Tuany Eichwald, Débora da Luz Scheffer, Leonardo Barros, Alexandre Solano, Vivian De Souza Menegassi, Ananda Christina Staats Pires, Camila Sartor Spivakoski, Rodrigo A. Da Silva, Joana M. Gaspar, Marcelo Fernando Ronsoni, Alexandra Latini

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