Translatome analysis reveals cellular network in DLK-dependent hippocampal glutamatergic neuron degeneration by Erin M Ritchie, Dilan Acar, Siming Zhong, Qianyi Pu, Yunbo Li, Binhai Zheng, Yishi Jin

Get full text

A qualitative study on optimizing influenza vaccination services and strategies for people aged 60 and above in Shanghai by WANG Xiaolan, YANG Tian, XUE Caoyi, WU Linlin, FEI Yi, YANG Xiaoguang, XU Biao

Get full text

Ways of improving the legal regulation of human organ and tissue transplantation in the Russian Federation by E. V. Karakulina, S. M. Khomyakov, O. A. Aleksandrova, I. V. Lysikov, S. V. Shedenko, S. V. Gautier

“…Measures on organ donation and transplantation in the Russian Federation have been approved within the «Healthcare Development», a framework of the state program of the Russian Federation. …”
Get full text

Autoimmune Diseases and Molecular Mimicry in Tuberculosis by Leonid P. Churilov, Muslimbek G. Normatov, Hong Ling, Min Zhuang, Dmitry Kudlay, Anna Starshinova

“…However, the molecular mimicry between <i>Mycobacterium tuberculosis</i> (Mtb) and human autoantigens is an important provocative factor in the development of autoimmunity on one hand. Mtb has already been widely discussed as a provocateur of autoimmunity in humans. …”
Get full text

Evaluating Bioassays for the Determination of Simvastatin’s Osteogenic Activity: A Systematic Review by Lara Steiner Back, Isabella Schönhofen Manso, Mariane Beatriz Sordi, Gabriel Leonardo Magrin, Águedo Aragonês, Ricardo de Souza Magini, Reinhard Gruber, Ariadne Cristiane Cabral Cruz

Get full text

A Double‐Humanized Murine Model in Bladder Cancer: A Novel Preclinical Model for Cancer Immunology Research by Niannian Ji, Zaineb Hassouneh, Shaun Trecarten, Zhen‐Ju Shu, Jaime Furman, Tyler J. Curiel, Robert S. Svatek, Neelam Mukherjee

Get full text

Selective Pyk2 inhibition enhances bone restoration through SCARA5-mediated bone marrow remodeling in ovariectomized mice by Yunqing Liu, Mai Nishiura, Mika Fujii, Sumiti Sandhu, Yasutaka Yawaka, Yutaka Yamazaki, Akira Hasebe, Tadahiro Iimura, Sek Won Kong, Ji-Won Lee

Get full text

Monitoring and Analysis of Relocation and Reclamation of Residential Areas Based on Multiple Remote Sensing Indices by Huiping Huang, Yingqi Wang, Chao Yuan, Wenlu Zhu, Yichen Tian

“…The relocation of residents from high-risk areas is a critical measure to address safety and development issues in the floodplain regions of Henan Province in China. …”
Get full text

Optimization of intraocular lens optical power calculation using artificial intelligence capabilities by A.R. Vinogradov, S.V. Balalin, E.G. Solodkova

“…The program interface was developed and implemented.…”
Get full text

Mechanistic Studies on the Role of IL-17/NLRP3 in Arsenic-Induced Activation of Hepatic Stellate Cells Through Hepatocyte Proptosis by Ting Hu, Mei Chen, Sai Tian, Peng Luo, Jiangping Zhang

“…Hepatocyte pyroptosis, a form of programmed cell death, is a critical factor in the occurrence of inflammation. …”
Get full text

Unveiling the power of plumbagin: revitalizing exhausted T cells to combat tongue cancer by Rongrong Zhang, Qingkun Jiang, Runying Guo, Ke Guo, Jiaxuan Qiu

“…This study aimed to evaluate the immunomodulatory effects of plumbagin in TSCC to facilitate the development of neoadjuvant immunotherapy strategies. …”
Get full text

Therapeutic gene editing in CD34+ hematopoietic progenitors from Fanconi anemia patients by Begoña Diez, Pietro Genovese, Francisco J Roman‐Rodriguez, Lara Alvarez, Giulia Schiroli, Laura Ugalde, Sandra Rodriguez‐Perales, Julian Sevilla, Cristina Diaz de Heredia, Michael C Holmes, Angelo Lombardo, Luigi Naldini, Juan Antonio Bueren, Paula Rio

Get full text

Prospects of epigenetic therapy of head and neck squamous cell carcinoma by R. N. Mustafin

“…To stimulate antitumor immune response, antibodies against such cell cycle checkpoints as programmed cell death 1 (pD-1) and programmed death-ligand 1 (pD-L1) are used. …”
Get full text

EVALUASI CAPAIAN PEMBERIAN FE PADA REMAJA PUTRI TULUNGAGUNG MELALUI KEGIATAN MAGANG MAHASISWA by Widadari Intan Rujaby, Trias Mahmudiono, Bekti Krisdyana

“…This achievement is still relatively low compared to the target of the National Medium-Term Development Plan (RPJMN) in 2021, which is 52%. …”
Get full text

Overexpression of WDFY2 inhibits prostate cancer cell growth and migration via inactivation of Akt pathway by Jianqing Wang, Xu Chen, Shijun Tong, Huihui Zhou, Jianliang Sun, Yuancheng Gou, Fei Wu, Jimeng Hu, Jianfeng Xu, Guanxiong Ding

Get full text

Impact of a Text Messaging Intervention as an In-Between Support to Diabetes Group Visits in Federally Qualified Health Centers: Cluster Randomized Controlled Study by Allie Z Yan, Erin M Staab, Daisy Nuñez, Mengqi Zhu, Wen Wan, Cynthia T Schaefer, Amanda Campbell, Michael T Quinn, Arshiya A Baig

“…MethodsA TMI was implemented for 11 health centers participating in a cluster randomized study of diabetes GVs in Midwestern FQHCs targeting adults with T2DM. FQHC patients participated in 6 monthly GVs either in person or online and a concurrent 25-week TMI. …”
Get full text

IL-1R2 promotes tumorigenesis and modulates the tumor immune microenvironment in colorectal cancer by Yanyan Lang, Hao Huang, Hongwei Jiang, Shaoxian Wu, Zhang Fang, Dachuan Zhang, Heya Qian, Yingting Liu, Maoling Yuan, Bin Xu, Lujun Chen, Xiao Zheng, Jingting Jiang

“…However, its precise role in tumor development and its impact on immune checkpoint inhibitors (ICIs) therapy in CRC remain poorly understood. …”
Get full text

Transformable self-assembling peptide nanoplatforms with tumor microenvironment responsiveness for tumor stem cell suppression and immunomodulation by Chen Wei, Xinyu Sun, Lijuan Gao, Yue Wang, Fantao Lin, Yao Du, Xiaoyu Zhao, Wei Gao, Jingkun Bai

“…In addition, the tumor microenvironment promotes the maintenance of BCSC stemness, inhibits immune cell activity, and forms an immune escape “barrier”. In this study, we developed an amphiphilic peptide nanocarrier system, PA/Pep1, with an RGD-targeting sequence. …”
Get full text

Unraveling the Mechanisms, Clinical Impact, Comparisons, and Safety Profiles of Slow-Release Therapies in Glaucoma by Marco Zeppieri, Caterina Gagliano, Daniele Tognetto, Mutali Musa, Federico Bernardo Rossi, Angelo Greggio, Giuliano Gualandi, Alessandro Galan, Silvia Babighian

Get full text

Modeling Aberrant Angiogenesis in Arteriovenous Malformations Using Endothelial Cells and Organoids for Pharmacological Treatment by Eun Jung Oh, Hyun Mi Kim, Suin Kwak, Ho Yun Chung

Get full text