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Mechanisms of induced resistance to the antitumoral agent ZZW-115 in pancreas ductal adenocarcinoma
Published 2025-07-01“…Nuclear protein 1 (NUPR1), a stress-responsive protein implicated in cancer progression and treatment resistance, represents a potential therapeutic target. Our laboratory has developed NUPR1 inhibitors such as ZZW-115. …”
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Global availability of guidelines related to assistive technology: a scoping review
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Bayesian joint-regression analysis of unbalanced series of on-farm trials
Published 2025-01-01“…Participatory plant breeding (PPB) is aimed at developing varieties adapted to agroecologically-based systems. …”
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Community-level mental health screening and referral using task-sharing with student volunteers in Kerala, India: a scalable model for low and middle income countries
Published 2025-04-01“…Structural fragmentation prevents effective screening and treatment, despite several policies and programs. The study presents a culturally tailored mental health campaign developed within a service design paradigm for mental health screening. …”
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The attitude of the unvaccinated children’s parents toward pediatric COVID-19 vaccination in Tabriz, Iran
Published 2025-03-01“…Understanding the reasons for parental reluctance to vaccinate their children is essential for developing effective public health strategies. This study aimed to assess the attitudes of parents with unvaccinated children aged 5–12 years toward COVID-19 vaccination and to explore their reasons for not vaccinating their children, despite having access to vaccination programs, in Tabriz, Iran. …”
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Changes of influenza vaccination rate and associated influencing factors after the COVID-19 pandemic in Shanghai, China
Published 2024-12-01“…The overall influenza vaccination coverage rate in Shanghai, especially among elderly individuals, is lower than many developed countries. Appropriate strategies and programs targeting different populations need to be implemented to enhance influenza vaccine coverage.…”
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From Simulation to Implementation: A Systems Model for Electric Bus Fleet Deployment in Metropolitan Areas
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Mechanistic PK/PD modeling to address early-stage biotherapeutic dosing feasibility questions
Published 2023-12-01“…Early assessment of dosing requirements should be an integral part of developability assessments for a discovery program. If a very high dose is required to achieve the desired pharmacological effect, it may not be clinically feasible or commercially desirable to develop the biotherapeutic for the selected target unless extra measures are taken to develop a high concentration formulation or maximize yield during manufacturing. …”
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Assessment of breeding lines of rice (Oryza sativa L.) carrying the Pi-40 gene for resistance to rice blast strains from Krasnodar region
Published 2016-08-01“…Couch, 2002, is one of the most harmful diseases of rice (Oryza sativa L.), and so the development of resistant varieties is important in rice breeding. …”
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How environmental stress will be spatially reconfigured under artificial sources and scale mismatch? A case in Yangtze River Delta, China
Published 2025-04-01“…Under high-quality development scenarios in 2035, multiple linear programming model recommends allocating 47,600 km2 for urban use, 145,800 km2 for agriculture, and 165,700 km2 for ecological conservation to meet environmental standards. …”
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Innovation Ecosystem of Iran's Tourism Industry with Emphasis on Supply Chain
Published 2024-01-01“…Today’s tourism products target more specific markets, with customers seeking authentic experiences. …”
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Current Tick Control Strategies and Prospects for Using Nanotechnology as an Efficient Alternative—A Review
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IMPORT SUBSTITUTION IN THE RUSSIAN TOURISM INDUSTRY
Published 2017-10-01“…The forms of the public-private partnershipin this area and the progress of the federal target program “The Development of the Domestic and Inbound Tourism in the Russian Federation (2011-2018)” are discussed. …”
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