Suggested Topics within your search.
Suggested Topics within your search.
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Wild <i>Coffea</i> Species: A Modern Genomic Approach to Unravel Variations for Future Cultivated Coffee Improvement
Published 2024-07-01“…The aim of this research is to target significant genetic variations that can be harnessed to develop superior coffee cultivars, ensuring sustainability and resilience in the face of changing environmental conditions. …”
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Effect of water, sanitation, and hygiene on the prevention of trachoma: a systematic review and meta-analysis.
Published 2014-02-01“…Though limitations included moderate to high heterogenity, low study quality, and the lack of standard definitions, these findings support the importance of WASH in trachoma elimination strategies and the need for the development of standardized approaches to measuring WASH in trachoma control programs.…”
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Dual Roles of SIRT7 Inhibition by Oroxylin A Reprogram HSCs Fate: PRMT5 Succinylation-Driven Senescence and Ecto-Calreticulin-Dependent NK Cell Immune Clearance in Liver Fibrosis
Published 2025-01-01“…This work establishes SIRT7 as a pivotal therapeutic target and provides mechanistic insights for developing antifibrotic strategies.…”
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TIGIT immunosuppressive role in female reproductive system malignant neoplasms: from mechanism to therapy
Published 2020-04-01“…TIGIT is a promising immunotherapeutic target in malignant neoplasms of the female reproductive system. …”
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Evolution of Allogeneic Stem Cell Transplantation: Main Focus on AML
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Decision Support System for Selecting Village Fund BLT Recipients using ROC and WASPAS Methods
Published 2025-07-01“…The Village Fund Direct Cash Assistance (BLT) Program is a government initiative aimed at improving social welfare, reducing inequality, and supporting economically disadvantaged communities. …”
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Supporting the editing of dot maps using the spectral clustering algorithm
Published 2025-01-01“…Particular attention should be paid to dot distribution maps, the editing of which is very time-consuming and complicated due to the lack of support in GIS programs. The aim of this research was to develop a method supporting automation of dot map creation. …”
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Estimating the extrinsic incubation period of malaria using a mechanistic model of sporogony.
Published 2021-02-01“…Our work highlights the importance of mechanistic modelling of sporogony to (1) improve estimates of malaria transmission under different environmental conditions or disease control programs and (2) evaluate novel interventions that target the mosquito life stages of the parasite.…”
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RETRACTED ARTICLE: Determining the role of innovative teaching practices, sustainable learning, and the adoption of e-learning tools in leveraging academic motivation for students’...
Published 2024-03-01“…Additionally, it was discovered that academic motivation helped the students to develop good academic record and mental health. Conclusion The research’s conclusions can help the policy makers creating successful educational initiatives and programs that promote students’ overall growth. …”
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Breakfast Habits, Anthropometry, and Nutrition‐Related Outcomes in Adolescents From Low‐ and Middle‐Income Countries: A Systematic Review and Meta‐Analysis
Published 2025-06-01“…Breakfast integrated within school feeding programs may be well positioned as a double‐duty solution to tackle malnutrition in all its forms among adolescents.…”
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Suppression of a Field Population of Aedes aegypti in Brazil by Sustained Release of Transgenic Male Mosquitoes.
Published 2015-01-01“…The increasing burden of dengue, and the relative failure of traditional vector control programs highlight the need to develop new control methods. …”
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Assessment of Board of Management’s Resource Mobilisation Practices on Effective Governance of Public Primary Schools in Nyeri County, Kenya
Published 2025-06-01“…The research used descriptive survey design and applied the steward theory. Target population was 352 public primary schools and 352 BOM chairpersons. …”
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Tumor microenvironment biomarkers predicting pathological response to neoadjuvant chemoimmunotherapy in locally advanced esophageal squamous cell carcinoma: post-hoc analysis of a...
Published 2024-08-01“…Cohort 3 consisted of 27 ESCC patients receiving neoadjuvant treatment of toripalimab with chemotherapy and was used as the external validation dataset. Targeted RNA sequencing, immunohistochemistry for programmed death ligand 1 (PD-L1), and multiplex immunofluorescence (mIF) imaging were performed.Results Integration of targeted RNA sequencing, PD-L1 immunohistochemistry, and mIF revealed a significant immune-suppressive microenvironment with higher neutrophil infiltration, enriched TGF-β, and cell cycle pathways in non-pathological complete response (non-pCR) patients. …”
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A Multifunctional Fe-EGCG@RSL3 Nanomedicine Synergizes Ferroptosis Induction and Tumor Microenvironment Remodeling for Enhanced Bladder Cancer Immunotherapy
Published 2025-01-01“…Ferroptosis has promising potential for augmenting antitumor effects, but monotherapy with ferroptosis inducers in vivo has been reported to have limited efficacy in tumor management. The development of synergistic strategies with targeted capabilities is crucial for enhancing the antitumor efficacy of ferroptosis inducers. …”
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SP140 inhibits STAT1 signaling, induces IFN-γ in tumor-associated macrophages, and is a predictive biomarker of immunotherapy response
Published 2022-12-01“…Background Understanding the role and potential therapeutic targeting of tumor-associated macrophages (TAMs) is crucial to developing new biomarkers and therapeutic strategies for cancer immunotherapies. …”
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Contemporary Management of Complex Ventricular Arrhythmias
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DNA methylation in melanoma immunotherapy: mechanisms and therapeutic opportunities
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National partnerships address critical needs in infection prevention and control
Published 2024-01-01“…The American Medical Association recruited eight physicians and one medical student to join their director of infectious diseases to develop educational programs targeting knowledge gaps. …”
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