Regulation of CXCR4 function by S1P1 through heteromerization by Hyun-Tae Kim, Jae-Yeon Jeong, Won-Ki Huh

“…Co-activation of S1P1 attenuated CXCL12-induced migration, while pretreatment with S1P or FTY720-phosphate increased CXCR4-mediated migration by downregulating surface S1P1 in KARPAS299 cells. In primary T cells, PLA confirmed CXCR4-S1P1 heteromerization, and S1P interfered with CXCL12-induced migration. …”
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Resolved ALMA [C ii] 158 μm Observations at Cosmic Noon: Interstellar Medium Structure and Dynamics of the Starbursting QSO SDSS J1000 by Christopher Rooney, Bo Peng, Amit Vishwas, Gordon Stacey, Thomas Nikola, Cody Lamarche, Catie Ball, Carl Ferkinhoff, Drew Brisbin, Steven Hailey-Dunsheath

“…We also report the discovery of a companion galaxy to J1 000 confirmed by the detection of [C ii ] and use recently obtained JWST/NIRCam imaging of the system to argue for J1 000 being an interacting system. …”
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Exposure assessment for air-to-skin uptake of traditional and emerging organophosphate flame retardants by Yujuan Fan, Ran Qi, Sicong Dong, Jing Zhang, Shiyu Shi, Youhua Zhao, Pengkun Wei, Guangxuan Yan, Ke Cheng, Huanjia Liu, Dan Yao, Chen Chen, Zhiguo Cao

“…A diffusion model was applied to the surface skin to simulate the OPFR concentration profiles and was compared with measured concentrations. …”
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MORPHOLOGICAL CONDITION OF THE MUCOUS DURING THE PERIOD OF PHYSIOLOGICAL CHANGE OF THE CANINES OF THE UPPER JAW by M. Cholovskyi

“…According to our data, more pronounced dystrophic and sclerotic processes were detected during vestibular placement of retained canines; instead, the processes of compensation and adjustment were less pronounced.Objective of the study: to determine the morphological features of the structure of the gums from the vestibular and palatal surfaces during the physiological change of canines. …”
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Fe-Cu-loaded γ-Al2O3 as an efficient heterogeneous Fenton catalyst for the advanced treatment of petrochemical wastewater by Shiqi Jiang, Changyong Wu, Qi Huang, Yin Yu, Peijian Zhang, Chenjie Wang, Xiyan Ou, Min Xu

“…The Fe(III)/Fe(II) and Cu(II)/Cu(I) redox pairs on the catalyst surface were identified as active sites for H2O2 activation. …”
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KIC 10855535: An Elegant δ Scuti Pulsator with Amplitude and Phase Modulation by Li-xian Shen, Ali Esamdin, Cheng-long Lv, Hao-zhi Wang, Tao-zhi Yang, Rivkat Karimov, Shuhrat A. Ehgamberdiev, Hu-biao Niu, Jin-zhong Liu

“…Two independent frequencies were detected: a pulsation frequency F0 = 17.733260(5) day ^−1 and a low frequency f _8 = 0.412643(8) day ^−1 . …”
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Analysis of RBP expression and binding sites identifies PTBP1 as a regulator of CD19 expression in B-ALL by Nicole Ziegler, Mariela Cortés-López, Francesca Alt, Maximilian Sprang, Arsenij Ustjanzew, Nadine Lehmann, Khalifa El Malki, Arthur Wingerter, Alexandra Russo, Olaf Beck, Sebastian Attig, Lea Roth, Julian König, Claudia Paret, Jörg Faber

“…Mutations in the CD19 locus and aberrant splicing events are known to account for the absence of surface antigen. However, early molecular determinants suggesting therapy resistance as well as the time point when first signs of epitope loss appear to be detectable are not enlightened so far. …”
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Exploring the potential processes controlling changes in precipitation–runoff relationships in non-stationary environments by T. Lan, T. Lan, T. Lan, T. Lan, T. Lan, T. Li, H. Zhang, H. Zhang, H. Zhang, J. Wu, J. Wu, J. Wu, Y. D. Chen, Y. D. Chen, C.-Y. Xu

“…Moreover, non-stationary hydrological processes were initially detected, and the nonlinear correlations among the factors were assessed. …”
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Thiol isomerase ERp18 enhances platelet activation and arterial thrombosis by Chao He, Aizhen Yang, Keyu Lv, Yuxin Zhang, Zhenzhen Zhao, Yi Lu, Chao Fang, Yue Han, Depei Wu, Miao Jiang, Jingyu Zhang, Yi Wu

“…Platelets from ERp18 knockout mice were used to detect aggregation, activation, spreading, and clot retraction. …”
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Repurposing of epalrestat for neuroprotection in parkinson’s disease via activation of the KEAP1/Nrf2 pathway by Huafang Jia, Mengru Liu, Hong Jiang, Zhen Qiao, Kaiyue Ren, Xixun Du, Xi Chen, Qian Jiao, Fengyuan Che

“…Immunofluorescence was used to detect dopaminergic (DAergic) neurons survival in the substantia nigra. …”
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Cytomegalovirus-induced oncomodulation drives immune escape in glioblastoma by Harald Krenzlin, Felix Corr, Deepak Ailani, Philipp Einheuser, Thomas Bukur, Thomas Rößler, Alina Henrich, Raja Hollnagel, Alice Dauth, Libo Hu, Leon Schmidt, Marion Griessl, Michael Gutknecht, Noe Mercado, Beat Alessandri, Charles H. Cook, Florian Ringel, Sean E. Lawler, Niels A. Lemmermann, Naureen Keric

“…Infection of mouse glioblastoma cells (GL261Luc2) with mCMV resulted in a short period of viral replication. MHC-I cell surface expression was reduced after mCMV infection by approximately 40% compared with non-infected tumor cells (p < 0.0001). …”
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Seroprevalence of transfusion-transmitted infections among blood donors in Makkah, Saudi Arabia by Faisal Minshawi, Asim A Abdulshakoor, Emran M Alwakil, Ghaiyda T Basfar, Saeed Kabrah, Akhmed Aslam, Hibah Almasmoum, Abdulrahman Mujalli, Rabab H Moaminah, Ghadeer A Almoalad, Mohammed A Alwadani, Mohammad G Alzahrani, Kholoud A Alsehemi, Bassem Refaat

“…Conclusions: Hepatitis B virus was the most frequently detected bloodborne pathogen, followed by hepatitis C virus and syphilis. …”
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Single cell viral tagging of Faecalibacterium prausnitzii reveals rare bacteriophages omitted by other techniques by Danielle E. Campbell, Xiaofen Wu, Lindsey R. Hall, Dylan Lawrence, Jerome M. Molleston, Lawrence A. Schriefer, Lindsay Droit, James S. Weagley, Benjamin S. Olson, Joanna Rimmer, Miles Parkes, Scott A. Handley, Megan T. Baldridge

“…Remarkably, VT also identified novel prophage integration events in F. prausnitzii, demonstrating that VT interactions can extend beyond the level of surface attachment and constitute active infection events. …”
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Intra-familial transmission of Hepatitis B virus in a peri-urban community from the Democratic Republic of the Congo by Florence Cindibu Kalonji, Yu Nakagama, Evariste Tshibangu-Kabamba, Nadine Kayiba Kalenda, Shun Nakagama, Sachie Nakagama, Pathy Kamanga Nkolongo, Nestor Kalala-Tshituka, Alphonse Lufuluabu Mpemba, Faustin Ndjibu Mpoji, André Kabongu Kalala, Benjamin Muamba Mpoyi, Dieudonné Mumba Ngoyi, Natsuko Kaku, Yusuke Shimakawa, Ghislain Tumba Disashi, Yasutoshi Kido

“…Participants were screened for hepatitis B surface antigen (HBsAg), followed by PCR amplification of HBV DNA and sequencing. …”
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Epidemiological Characteristics and Prognostic Scoring in Toxic Epidermal Necrolysis and Stevens–Johnson Syndrome: Insights from a 17-Year Burn Center Experience by David Breidung, Sarina Delavari, Ioannis-Fivos Megas, Alexander Geierlehner, Wolfgang Hitzl, Karl J. Bodenschatz, Konrad Karcz, Denis Ehrl, Moritz Billner

“…A classification tree was created to detect unknown determinants of SJS/TEN mortality. …”
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Insights into the role of MSLN-positive circulating tumor cell as an auxiliary diagnostic biomarker in epithelial ovarian cancer by Hang Xu, Min Wang, Shuting Wu, Qinke Li, Jinlong Wang, Siying Zhang, Qiongming Liu, Mengting Wang, Ruifang Li, Zhiyuan Hu, Zhiyuan Hu, Yi Liu, Zhu Yang

“…In a prospective cohort of 35 patients with undiagnosed ovarian masses, we employed immunofluorescence staining to detect MSLN-positive circulating tumor cells (MSLN(+)CTCs) and assessed their diagnostic performance using receiver operating characteristic (ROC) analysis.ResultsMSLN was highly expressed in EOC cell line and tissues but lowly expressed in normal ovarian surface epithelial tissues. …”
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The Synthesis and Characterization of CdS Nanostructures Using a SiO₂/Si Ion-Track Template by Aiman Akylbekova, Kyzdarkhan Mantiyeva, Alma Dauletbekova, Abdirash Akilbekov, Zein Baimukhanov, Liudmila Vlasukova, Gulnara Aralbayeva, Ainash Abdrakhmetova, Assyl-Dastan Bazarbek, Fariza Abdihalikova

“…After CdS synthesis, the surfaces of nanoporous SiO_2 nanopores/Si were examined using a scanning electron microscope to determine the pore sizes and the degree of pore filling. …”
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Short-term use of ceftriaxone sodium leads to intestinal barrier disruption and ultrastructural changes of kidney in SD rats by Wenli Zou, Yueming Liu, Wei Zhang, Bo Lin, Wei Shen, Yiwen Li, Qiang He, Juan Jin

“…TEM examination of colon revealed that dramatic morphological changes were observed in the ceftriaxone (Cef) group, wherein microvilli were misaligned and shortened significantly and morphologically intact bacteria were seen on the epithelial cell surface. TEM examination of kidneys from the Cef group showed characteristic glomerular changes in the form of widely irregularly thickened glomerular basement membrane (GBM) and foot process fusion or effacement; mild thickening of the GBM and foot process fusion was detected when ceftriaxone and Resatorvid (TAK242, an inhibitor of TLR4 signaling) are used together in the ceftriaxone + TAK242 (TAK) group.Conclusions Short-term use of ceftriaxone induced dynamic changes of gut microbiota and lead to intestinal barrier disruption and ultrastructural changes of kidneys in the SD rats. …”
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The role of stem and progenitor cells in the regeneration of the pancreas and testes in metabolic disorders by A. V. Pakhomova, O. V. Pershina, V. A. Krupin, L. A. Ermolaeva, N. N. Ermakova, A. I. Kudryashova, A. M. Dygai, E. S. Pan, O. Yu. Rybalkina, E. G. Skurikhin

“…We used cytometric methods to study the surface markers of stem and progenitor cells, culture methods and transplantation test to investigate the regenerative potential of stem and progenitor cells.Results. …”
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Development of an indicator system for solar-induced chlorophyll fluorescence monitoring to enhance early warning of flash drought by Zixuan Qi, Yuchen Ye, Lian Sun, Chaoxia Yuan, Yanpeng Cai, Yulei Xie, Guanhui Cheng, Pingping Zhang

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