Análise contra o conceito de trauma cultural: ou como aprendi a amar o sofrimento dos outros sem ajuda da psicoterapia by Wulf Kansteiner, Harald Weilnböck

“…At that point in time, a few very influential texts, especially the publications of Cathy Caruth, helped establish a fairly homogenously structured interdisciplinary terrain that celebrated cultural trauma as a welcome disruption of existing cultural hegemonies and master narratives. …”
Get full text

Norcantharidin inhibits TOP2A expression via H3K27me3 mediated epigenetic regulation to alleviate the progression of hepatocellular carcinoma by Ruibing Wu, Hengye Yuan, Yuehua Wang, Xianggang Gou, Wanhua Hou, Zhongzheng Zhou, Xinran Wang, Xiuling Deng, Changshan Wang, Haisheng Wang, Jia Yan, Jia Yan

“…Mechanistic investigations demonstrated that NCTD epigenetically suppresses TOP2A transcription via PRC2 (Polycomb Repressive Complex 2)-mediated deposition of the repressive histone mark H3K27me3 at the TOP2A promoter. …”
Get full text

Aurora kinase B is required for growth and expansion of medulloblastoma cells in the tissue context by Alexandre Gries, Karthiga Santhana Kumar, Fabien Kuttler, Özgün Özalp, Veronica Akle, Hanqing Zhang, Michael A. Grotzer, Stephan C.F. Neuhauss, Amin Allalou, Martin Baumgartner

“…We validated tumor suppressive activities of the AURKB inhibitor (AURKBi) Barasertib (AZD1152-HQPA) and the structurally unrelated compound GSK-1070916 in cerebellum slice culture models for SHH, and Grp3 MB. …”
Get full text

The regulation of complementary and alternative medicine professions in Ontario, Canada by Jeremy Y. Ng

“…Alford’s model of dominant, challenging and repressed structured interests (DSIs, CSIs, and RSIs respectively) is used to describe the competition between various players within the healthcare system and their position in the health policy process. …”
Get full text

Participation of NKVD and Prosecutor’s Office in Ensuring Construction of Kuibyshev Defensive Line (November 1941 — January 1942) by A. G. Pashkin, R. A. Mukhamedov

“…In the course of the work, it was proved that by mid-December 1941 the repressive policy had been curtailed, and local authorities took measures to improve the food supply for workers.…”
Get full text

The intrinsic antiviral defense to incoming HSV-1 genomes includes specific DNA repair proteins and is counteracted by the viral protein ICP0. by Caroline E Lilley, Mira S Chaurushiya, Chris Boutell, Roger D Everett, Matthew D Weitzman

“…During the initial stages of HSV-1 infection, novel sub-nuclear structures containing these ND10 proteins form in association with incoming viral genomes. …”
Get full text

Molecular basis of ligand-dependent Nurr1-RXRα activation by Xiaoyu Yu, Jinsai Shang, Douglas J Kojetin

Get full text

The Fake History: Soviet Totalitarianism and the Memory of the Guerrilla War by Bernardas Gailius

“…The systematic Soviet repressions were aimed at the complete destruction of the Lithuanian social pattern. …”
Get full text

Pharmacological Inhibition of Astrocytic Transglutaminase 2 Facilitates the Expression of a Neurosupportive Astrocyte Reactive Phenotype in Association with Increased Histone Acety... by Thomas Delgado, Jacen Emerson, Matthew Hong, Jeffrey W. Keillor, Gail V. W. Johnson

“…Astrocytes play critical roles in supporting structural and metabolic homeostasis in the central nervous system (CNS). …”
Get full text

Nalchik District during the Russian Revolution (1917-1920): The Chaotization of Violence by Osman A. Zhansitov

“…Moreover, militarized structures subordinate to the authorities, such as regular army units or popular militias, often used unauthorized repressive practices. …”
Get full text

Gulag Poetry as Literary Testimony: Poetical and Epistemic Framework by Claudia Pieralli

“…The present survey aims at presenting the corpus of verses composed by the victims of рolitical repressions in the Soviet Union from the point of view of published collections and main critical works, concerning, above all, Stalinian era’s texts. …”
Get full text

Peculiarities of the molecular composition of heterochromatin associated with pronucleoli in mouse embryos by I. O. Bogolyubova, Z. K. Sailau, D. S. Bogolyubov

“…The NPBs are fibrillar electron-dense structures inactive in RNA synthesis. The vast majority of NPBs are surrounded by a ring-shaped zone of transcriptionally inactive heterochromatin. …”
Get full text

DU MOI « CRYPTOPHORE » AU MOI IDENTITAIRE DE NADIA : L’ÉCRITURE THÉRAPEUTIQUE DANS LE ROMAN INSTRUMENTS DES TÉNÈBRES DE NANCY HUSTON by Teodora Maria POP

“…Starting from the filial bond and from the maternal characteristics transmitted hereditarily, but also acquired through imitation behaviour, our analysis follows the deconstruction of identity self and the consequences over the psyche of the childhood memories repressed in the Unconscious. The mutations of the psychic structures thus lead to split personality and to the configuration of the cryptophore woman’s typology that repeatedly reconstructs the lived traumas: the loss of the mother, the child and the brother. …”
Get full text

Aberrant EZHIP expression drives tumorigenesis in osteosarcoma by Wajih Jawhar, Geoffroy Danieau, Alva Annett, Takeaki Ishii, Andrea Bajic, Ana Castillo-Orozco, Brian Krug, Yara Faucher-Jabado, Justin Seyedmoomenkashi, Mostafa Saquib, Masoumeh Aghababazadeh, Marjan Khatami, Nadim Tawil, Damien Faury, Sungmi Jung, Ahmed Aoude, Robert E. Turcotte, Benjamin Ellezam, Thomas Sontag, Sylvie Langlois, Daniel Sinnett, Swneke D. Bailey, Lingxin Zhang, Dorothée Dal Soglio, Claudia L. Kleinman, Nada Jabado, Livia Garzia

“…Abstract Osteosarcomas (OS) are aggressive bone tumors known for their extensive structural variations and rare recurrent oncogenic driver mutations. …”
Get full text

Multiscale juridification of the mining industry: Experiences in Central America and Mexico by Ainhoa Montoya, Rachel Sieder, Yacotzin Bravo-Espinosa

“…In this article, we expose the complex relationships between the multiscale landscape of global legal pluralism that structures socioenvironmental conflicts over mining, the processes of juridification and the varied forms of violence that motivate quests for justice. …”
Get full text

Dynamics of Platform Architecture and Labor Unrest: Mobilizing and Contesting Solidarity in the 2021–2022 Foodpanda Delivery Rider Strikes in Hong Kong by Ngai Keung Chan

“…Algorithmic control also serves as a repressive tool to demobilize workers. Thus, solidarity was fragmented and transient. …”
Get full text

Long-term senolytic therapy with Dasatinib and Quercetin alleviates lipofuscin-dependent retinal degeneration in mice by Bo Yang, Kunhuan Yang, Ruitong Xi, Shiying Li, Jingmeng Chen, Yalin Wu

“…Importantly, the long-term D + Q regimen significantly alleviated the degeneration of retinal structures and function in 8-month-old Abca4−/−Rdh8−/− mice, and it effectively repressed cellular senescence, lysosomal alkalinization, lipofuscin accumulation and oxidative stress in the RPE. …”
Get full text

ZNFX1 suppresses apoptosis-associated mRNA stability in cardiomyocyte to protect against myocardial infarction by Yang Shi, Zeqi Sun, Yongchao Chen, Yanli Xie, Chen Chen, Han Lou, Jan Mohammad Omar, Lei Wang, Ling Liu, Heng Liu, Limin Zhao, Henghui Xu, Xiaohan Li, Run Xu, Zhouxiu Chen, Khuzin Dinislam, Yong Zhang, Xin Liu

“…Mechanistically, RNA-seq identified apoptosis as a possible regulated pathway of ZNFX1, overexpression of ZNFX1 repressed the cardiomyocyte apoptosis that gives rise to MI while knockdown of ZNFX1 deteriorated it. …”
Get full text

Transcriptome and Proteome Reveal Heat Shock Promotes Haploid Induction Rate via Activating ABA Signal Transduction in Watermelon by Shiqi Gong, Bingqian Tang, Yujuan Dai, Xiangyu Sun, Huijuan Song, Cheng Xiong, Tian Zou, Longjun Sun, Guang Liu, Hongbo Yang, Shengxiu Zhu, Sihui Dai, Xiaowu Sun

“…Previous researchers found that heat shock can increase the rate of Embryo-like structures (ELSs) induction. However, molecular mechanisms underlying heat-shocked haploid induction remain poorly understood. …”
Get full text

Epigenetic regulation and mechanobiological adaptation in tenocytes during maturation by Ellen Y. Zhang, Tyler E. Blanch, Saeed B. Ahmed, Xi Jiang, Nathaniel A. Dyment, Su Chin Heo

“…While prior studies have characterized the mechanical and structural changes in tendons during maturation, the epigenetic regulation of tenocyte function during aging remains poorly understood. …”
Get full text