The impact of referral workload on cardiology registrars in a high-volume district general hospital: implications for workforce well-being and service efficiency by Md Imran Hossain, Jaymin Shantilal Shah

“…Chi-square tests and non-parametric correlation analyses evaluated relationships among workload perception, stress and exhaustion. …”
Get full text

Toll-like receptor 8 agonists improve NK-cell function primarily targeting CD56brightCD16− subset by Enrico Maggi, Giovanni Scambia, Anna Fagotti, Lorenzo Moretta, Andrea Pelosi, Irene Veneziani, Valentina D'Oria, Claudia Alicata, Nadine Landolina, Biancamaria Ricci

“…Background Toll-like receptors (TLRs) are pattern-recognition sensors mainly expressed in innate immune cells that directly recognize conserved pathogen structures (pathogen-associated molecular patterns-PAMPs). …”
Get full text

Extracting individual trajectories from text by fusing large language models with diverse knowledge by Le Liu, Tao Pei, Zidong Fang, Xiaorui Yan, Chenglong Zheng, Xi Wang, Ci Song, Wenfei Luan, Jie Chen

“…While general-purpose large language models (LLMs) demonstrate potential for contextual reasoning capabilities, their deficient domain-specific knowledge pertinent to trajectory patterns hinders efficient and precise trajectory extraction. …”
Get full text

The Role of Values and Emotions in Accepting Fake Political News in the Post-Truth Era by Amir Mollaee Mozaffari, Ali Ashraf Nazari

“…The interview data were analyzed using Discursive Psychology, focusing on the linguistic patterns and discourse structures in the participants' responses. …”
Get full text

Developing Laterality-Specific Computable Phenotypes from Electronic Health Record Data, Employing Treatment-Warranted Diabetic Macular Edema as a Use Case by Kaili Ding, MBBS, MS, Tracy Z. Lang, BS, Roberta McKean-Cowdin, PhD, Hossein Ameri, MD, PhD, Narsing A. Rao, MD, Brian C. Toy, MD

“…Laterality data completeness was evaluated for each category, independently and in a tiered hierarchical order. …”
Get full text

Ecological and climatic transferability of airborne lidar-driven aboveground biomass models in Piñon-Juniper woodlands by Jessie F. Eastburn, Michael J. Campbell, Philip E. Dennison, William Rl Anderegg, Kevin J. Barrett, Patrick A. Fekety, Samuel W. Flake, David W. Huffman, Steven A. Kannenberg, Kelly L. Kerr, Andrew J. Sánchez Meador, Jody C. Vogeler

“…The dynamism of PJ woodland extent and abundance over space and time is attributable to variability in species compositions, stand structures, climatic conditions, and disturbance patterns. …”
Get full text

Synthesis of biosafe spirulina-derived carbon dots and their fluorescence imaging in zebrafish by Yue Wang, Zhizhi Gu, Jingyi Dong, Cunguang Liu, Jie Zhu, Zixu Wang, Jiaying Li, Meichen Lu, Jian Han, Shengnan Cao, Zhuang Xue, Yan Chen, Liyong Chen, Wei Wang

“…These CDs possess excellent tissue penetration capabilities and specific accumulation patterns, facilitating clear visualization of anatomical structures. …”
Get full text

Examining the evolution and impact of OTC vending machines in Global Healthcare Systems by Ammar Abdulrahman Jairoun, Sabaa Saleh Al-Hemyari, Moyad Shahwan, Sahab Alkhoujah, Faris El-Dahiyat, Ammar Ali Saleh Jaber, Sa'ed H. Zyoud

“…Objectives: This study involves a bibliometric quantitative analysis of academic literature to evaluate OTC vending machines in terms of their evolution, current trends, and potential areas for future research. …”
Get full text

Developmental changes of skin quality from breast, back, and thigh of Pekin ducks from 1 to 6 weeks of age by Hao Li, Wenxuan Zheng, Shuo Xin, Ye Hui, Yijun Zhu, Xi Lin, Huaqi Zhang, Yongwen Zhu

“…In conclusion, the developmental pattern of skin growth and structure of Pekin ducks in a linear manner with increased age. …”
Get full text

Remote sensing-based analysis of yield and water-fertilizer use efficiency in winter wheat management by Weiguang Zhai, Qian Cheng, Fuyi Duan, Xiuqiao Huang, Zhen Chen

“…Subsequently, the effects of different water and fertilizer treatments on winter wheat yield and water-fertilizer use efficiency were evaluated, and the response patterns between winter wheat spectral features (normalized difference vegetation index, NDVI) and texture features (Contrast) and yield and water-fertilizer use efficiency were analyzed. …”
Get full text

Exploring Scientific Outputs about Globalization: A Conceptual Framework Study by Saleh Rahimi, Faramarz Soheili

“…By analyzing term co-occurrences, this approach revealed underlying thematic clusters, prevailing trends, and evolving patterns over time, providing a dynamic perspective for interpreting the intellectual structure of a research domain.  …”
Get full text

Understanding the influence of precipitation and nitrogen depositions on the soil health and growth indices of invasive (Solidago canadensis L.) and native (Wedelia chinesis) assoc... by Ismail Khan, Muhammad Tariq, Faisal Nadeem, Muhammad Sadiq Khan, Sulaiman Ali Alharbi, Saleh Alfarraj, Sezai Ercisli, Ayse Usanmaz Bozhuyuk, Ping Zhuang

“…Variable precipitation patterns and nitrogen (N) deposition rates have influenced plant community structure and productivity in different ecosystems. …”
Get full text

Development and Validation of a Brain Aging Biomarker in Middle-Aged and Older Adults: Deep Learning Approach by Zihan Li, Jun Li, Jiahui Li, Mengying Wang, Andi Xu, Yushu Huang, Qi Yu, Lingzhi Zhang, Yingjun Li, Zilin Li, Xifeng Wu, Jiajun Bu, Wenyuan Li

“…Model performance was evaluated using mean absolute error (MAE) against benchmark models, while generalization capability was further validated on an external UK Biobank dataset. …”
Get full text

Multicenter study correlating molecular characteristics and clinical outcomes of cancer cases with patient-derived organoids by Paloma Navarro, Tatiana P. Grazioso, Arantzazu Barquín, Maria Barba, Mónica Yagüe, Carlos Millán, Irene López, Elena Sevillano, Miguel Quiralte, Paloma Fernández, Diego Losada, Eduardo Caleiras, Julia Calzas, Beatriz Jiménez, Sergio Ruiz-Llorente, Juan Justo, Félix Guerrero, Vital Hevia, Raquel Martín, Francisco José Pérez-Rodriguez, Julia Tejerina, Mario Prieto, Paula Comune, Juan Francisco Rodriguez-Moreno, Jesús García-Donás

“…Abstract Background 3D-spatial interaction between cancer cells influences tumor behavior, making it essential to replicate tumor structures for predicting patient outcomes. Methods We collected data from three multicenter prospective studies to evaluate the ability to establish Patient-Derived Organoids (PDOs) from different biological samples and timepoints, correlating their characteristics and drug sensitivity with clinical outcomes. …”
Get full text

Case Report: A 55 kg retroperitoneal liposarcoma by Ren Yingzheng, An Junjie, Wang Guifei, Yang Yang, Dong Long, Jiang Linlin, Fang Zhiqiang, Bi Xiaogang, Dong Yonghong

“…Retroperitoneal liposarcoma (RPLS), particularly the well-differentiated subtype, often presents as large masses due to its deep anatomical location and indolent growth pattern. Moreover, its frequent adherence to vital structures poses significant challenges for complete surgical resection.Case presentationA 62-year-old male was admitted to the hospital due to the gradual enlargement of a mass in the abdomen and pelvis over the past 20 years. …”
Get full text

A Polysorbate-Based Lipid Nanoparticle Vaccine Formulation Induces In Vivo Immune Response Against SARS-CoV-2 by Aishwarya Saraswat, Alireza Nomani, Lin-Kin Yong, Jimmy Chun-Tien Kuo, Heather Brown, Muralikrishna Narayanareddygari, Avery Peace, Rizan Fazily, Timothy Blake, Christopher D. Petro, Bindhu Rayaprolu, Johanna Hansen, Amardeep Singh Bhalla, Mohammed Shameem

“…We hypothesized that substituting conventional linear PEG-lipids with PS-80, a widely used, biocompatible injectable surfactant featuring a branched PEG-like structure, may change the LNPs biodistribution pattern and enhance long-term stability. …”
Get full text

Opportunities and limitations of CT - assessment of neoadjuvant chemoradiation therapy of gastric cancer by T. A. Agababyan, N. K. Silanteva, V. Yu. Skoropad, S. A. Ivanov, A. D. Kaprin, Yu. A. Komin, A. Yu. Usacheva, D. D. Kudryavtsev

“…The maximal wall thickness (p<0.001) and the maximal area of the tumor (p<0.001) decreased significantly in postchemoradiotherapy scans compared to the baseline.CT texture analysis after the completion of radiochemotherapy showed that the primary tumors became more homogenous with the multilayer pattern, especially in the peripheral portion of the residual tumor, a marked enhancement of the mucosal layer of the stomach in 17 of 24 patients (71%) in the arterial phase and in 20 of 24 patients (83%) in the portal and/or venous phases.Accurate measurement of the tumor before and after the therapy allowed the evaluating the response to therapy by RECIST 1.1 criteria. …”
Get full text

Acute Hepatitis A-Induced Autoimmune Hepatitis: A Case Report by Brenda N. Loza-Hernández, Héctor M. Herrera-Martínez, Erika G. Salgado-Parra, Arturo-Rodríguez Guajardo, Violeta López-Gutierrez, Mauricio Old-Morales

“…Exposure to external factors is considered necessary to trigger the autoimmune reaction against hepatic structures.…”
Get full text

Re-composing Physical Form with Energy-Based Resilience Approach to Improve Thermal Comfort (Case Study: Sadra New Town) by Sahar Akbari, Mahsa Sholeh, Sahand Lotfi

“…The evaluation result showed that no part of the neighborhood is in the optimal temperature range. …”
Get full text

Intra-articular Glenoid Fracture Managed by Arthroscopic Fixation and Open Reduction and Internal Fixation Techniques: An Analytical Study by Prahalad K Singhi, Sivakumar Raju, Chidambaram Muthu, Gopi Kumarasamy, Vinoth Thangamani, Muthukishore Marichamy

“…Due to complex anatomy and neurovascular structures in vicinity, operative treatment is relatively uncommon. …”
Get full text