Showing 1 - 20 results of 22 for search 'striking sequence optimization', query time: 0.11s Refine Results
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    A comprehensive analysis of in vitro and in vivo genetic fitness of Pseudomonas aeruginosa using high-throughput sequencing of transposon libraries. by David Skurnik, Damien Roux, Hugues Aschard, Vincent Cattoir, Deborah Yoder-Himes, Stephen Lory, Gerald B Pier

    Published 2013-01-01
    “…High-throughput sequencing of transposon (Tn) libraries created within entire genomes identifies and quantifies the contribution of individual genes and operons to the fitness of organisms in different environments. …”
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    Article
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    Challenges in adjusting scoring matrices when comparing functional motifs with non-standard compositions by Patryk Jarnot

    Published 2024-12-01
    “…Abstract Methods for scoring matrix adjustment decrease the significance of biased residues to better detect homology between protein sequences. This is because non-homologous proteins often contain fragments with non-standard compositions that are strikingly similar to each other. …”
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    Application of Optimized Adaptive Neuro-Fuzzy Inference for High Frame Rate Video Quality Assessment by Marko Matulin, Štefica Mrvelj, Marko Periša, Ivan Grgurević

    Published 2025-04-01
    “…The subtractive clustering parameters were optimized to strike a balance between model complexity and predictive accuracy. …”
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    Modelling Population Genetic Screening in Rare Neurodegenerative Diseases by Thomas P. Spargo, Alfredo Iacoangeli, Mina Ryten, Francesca Forzano, Neil Pearce, Ammar Al-Chalabi

    Published 2025-04-01
    “…<b>Conclusions and Relevance:</b> We show that risk following a positive screening test result can be strikingly low for rare neurological diseases, even for fully penetrant variants such as <i>HTT</i>, if the test has sub-optimal performance. …”
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    Robust genetic codes enhance protein evolvability. by Hana Rozhoňová, Carlos Martí-Gómez, David M McCandlish, Joshua L Payne

    Published 2024-05-01
    “…Whereas the genetic codes that optimize evolvability depend to some extent on the detailed relationship between amino acid sequence and protein function, we also uncover general design principles for engineering nonstandard genetic codes for enhanced and diminished evolvability, which may facilitate directed protein evolution experiments and the bio-containment of synthetic organisms, respectively.…”
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    A study on phonemes recognition method for Mandarin pronunciation based on improved Zipformer-RNN-T(Pruned) modeling. by Zhaohui Du, Xiaofeng Zhao, Lin Li, Baohua Yu, Lijiang Miao

    Published 2025-01-01
    “…Currently, the mainstream pronunciation assessment models rely on advanced speech recognition technology, converting speech into phoneme sequences, and then determining mispronounced phonemes through sequence comparison. …”
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    Dissection of a rice OsMac1 mRNA 5' UTR to uncover regulatory elements that are responsible for its efficient translation. by Hiromi Mutsuro-Aoki, Hiroshi Teramura, Ryoko Tamukai, Miho Fukui, Hiroaki Kusano, Mikhail Schepetilnikov, Lyubov A Ryabova, Hiroaki Shimada

    Published 2021-01-01
    “…Mutation analysis of UTRc demonstrated that an optimal sequence length of sp38, rather than its nucleotide sequence is essential for UTRc to promote efficient translation. …”
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    Unveiling immune cell response disparities in human primary cancer-associated fibroblasts between two- and three-dimensional cultures. by Jian-Ping Yang, Nikhil Nitin Kulkarni, Masashi Yamaji, Tsubasa Shiraishi, Thang Pham, Han Do, Nicole Aiello, Michael Shaw, Toshihiro Nakamura, Akiko Abiru, Narender R Gavva, Shane R Horman

    Published 2024-01-01
    “…Cancer-associated fibroblasts (CAFs) play pivotal roles in solid tumor initiation, growth, and immune evasion. However, the optimal biomimetic modeling conditions remain elusive. …”
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    Hydrocarbon enrichment regularity of the first member of Paleogene Dainan Formation in Qintong Sag, Subei Basin by TAI Hao,YU Wenduan,ZANG Suhua,SHI Mengjun,JING Xiaobo,SUN Wei

    Published 2023-12-01
    “…The study shows that the fan delta front facies belt is a favorable area for the development of lithologic oil reservoirs, and the sand shale interbed near the largest lake flooding surface is the optimal reservoir cap combination vertically, The formation of oil and gas reservoirs in the first member of Dainan Formation is jointly controlled by the structural background, sedimentary facies belts, and regional strike slip structural belts. …”
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    Hybrid GIS-Transformer Approach for Forecasting Sentinel-1 Displacement Time Series by Lama Moualla, Alessio Rucci, Giampiero Naletto, Nantheera Anantrasirichai, Vania Da Deppo

    Published 2025-07-01
    “…Empirical analysis determined that optimal forecasting is achieved with a 50-time-step input sequence, and that predicting 10% of the input sequence length strikes a balance between temporal coverage and accuracy. …”
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    Synaptic Structure and Transcriptomic Profiling of Reward and Sensory Brain Areas in Male Mice of Fentanyl Addiction by Feng J, Xu N, Wang L, Wang H, Zhou Y, Shen Q

    Published 2024-12-01
    “…These transcriptomic changes may be correlated with the structural and behavioral changes observed in fentanyl-exposed mice.Discussion: The findings of this study contribute to a better understanding of the molecular mechanism of addiction behavior, which is essential for the development of optimized therapy strategies for addicts.Keywords: fentanyl, addiction, synaptic plasticity, gene expression, transcriptional profiles…”
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    Generation of Individualized, Standardized, and Electrically Synchronized Human Midbrain Organoids by Sanae El Harane, Bahareh Nazari, Nadia El Harane, Manon Locatelli, Bochra Zidi, Stéphane Durual, Abderrahim Karmime, Florence Ravier, Adrien Roux, Luc Stoppini, Olivier Preynat-Seauve, Karl-Heinz Krause

    Published 2025-08-01
    “…Air–liquid interface organoids (3D-ALi) showed optimized size and shape standardization. RNA sequencing and immunostaining confirmed neural/dopaminergic specification. …”
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    Selective ligand recognition by a diversity-generating retroelement variable protein. by Jason L Miller, Johanne Le Coq, Asher Hodes, Roman Barbalat, Jeff F Miller, Partho Ghosh

    Published 2008-06-01
    “…Diversity-generating retroelements (DGRs) recognize novel ligands through massive protein sequence variation, a property shared uniquely with the adaptive immune response. …”
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    Method of adaptive component-based design of unmanned aerial vehicles suitable for military missions by Oleg Fedorovich, Leonid Malieiev, Tetyana Pisklova, Yevhenii Polishchuk

    Published 2025-05-01
    “…The research utilizes a range of mathematical methods and models, including: systems analysis for adaptive project activities related to UAV development; component-based UAV design method; lexicographic ordering for ranking design alternatives; expert evaluation techniques for identifying the most rational UAV configuration; targeted search method for optimal developer team formation using integer (Boolean) programming; and simulation modeling to plan the sequence of project activities for adapting UAV component architectures to new military applications. …”
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    Research on entity recognition and alignment of APT attack based on Bert and BiLSTM-CRF by Xiuzhang YANG, Guojun PENG, Zichuan LI, Yangqi LYU, Side LIU, Chenguang LI

    Published 2022-06-01
    “…The attention mechanism is built to highlight key features and convert the vector sequence into an annotation probability matrix. Thirdly, the CRF algorithm is utilized to decode the relationship between the output predicted labels and generate the optimal label sequence. …”
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    Research on entity recognition and alignment of APT attack based on Bert and BiLSTM-CRF by Xiuzhang YANG, Guojun PENG, Zichuan LI, Yangqi LYU, Side LIU, Chenguang LI

    Published 2022-06-01
    “…The attention mechanism is built to highlight key features and convert the vector sequence into an annotation probability matrix. Thirdly, the CRF algorithm is utilized to decode the relationship between the output predicted labels and generate the optimal label sequence. …”
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    Article
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    A Secure Communication Method for Unmanned Undersea Systems Oriented to Federated Learning by Jiajia WU, Ming XU

    Published 2025-04-01
    “…By adopting multi-objective optimization techniques, the Pareto optimal solution was found to strike a balance between model accuracy and secure throughput. …”
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