CD248 induces PD-L1 expression on cancer-associated fibroblasts to promote NSCLC immune escape by Zeyang Yang, Xuanyin Wang, Xu Zhu, Xu Zhu, Long Li, Long Li, Xianling Zeng, Jiaming Ren, Jiaming Ren, Lu Wang, Jiangwei Wu, Qiaoling Zhang, Siyu Wang, Maoqin Lu, Juan Zhai, Xinlei Liu, Jing Xiao, Tao Jin, Ying Zhang, Yun Wang, Yun Wang, Jian Zhang, Zhu Zeng, Zhu Zeng, Zhu Zeng, Jieheng Wu, Jieheng Wu, Jieheng Wu, Jieheng Wu, Jieheng Wu

“…BackgroundTumor immune escape is a critical step in tumor progression. Cancer-associated fibroblasts (CAFs) in the tumor microenvironment (TME) express abundant PD-L1 and suppress the functions of CD8+T cells, enablingd immune escape. …”
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Cytokines and HIV associated neurological manifestations: a systematic review by S. SeyedAlinaghi, A.M. Afsahi, P. Mirzapour, S. Alikarami, A. Afzalian, P. Matini, S. Mahrokhi, Z. Ali, A. Pashaei, S. Eslami, F. Vahedi, P. Paranjkhoo, M.A. Habibi, A. Molla, A. Dadjou, S.N. Parikhani, Esmaeil Mehraeen, D. Hackett

“…There is an interconnecting pathway of cytokines, neurological function (mainly dementia), and sleep habits in people living with HIV. …”
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The Effect of Hearing Aid Amplification on Gait Parameters: A Pilot Study Using Ear-Worn Motion Sensors by Ann-Kristin Seifer, Arne Küderle, Kaja Strobel, Ronny Hannemann, Björn M. Eskofier

“…<b>Background/Objectives</b>: Hearing loss, particularly in older adults, is associated with reduced physical functioning; increased fall risk; and altered gait patterns, including slower walking speed and shorter step length. …”
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Experimental Evaluation of Dry and Contactless Cleaning Methods for the Production of Digital Vehicle Dashboards by Patrick Brag, Yvonne Holzapfel, Marcel Daumüller, Ralf Grimme, Uwe Mai, Tobias Iseringhausen

“…Particulate contamination inside BLUs can lead to either an aesthetic or functional failure and is in consequence a part of quality control. …”
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Exploring the Potential of ChatGPT in Developing a Virtual Assistant for Prevention and Support in Cases of School Bullying by Rodolfo Mendoza Pinto

“…Although this research focused on the technical functionality of the chatbot, its implementation in students and data analysis of user interactions represent important future steps. …”
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Ultrafast longitudinal and transverse dielectric response of collective polar modes in liquids by Matthias Runge, Michael Woerner, Thomas Elsaesser

“…The resulting changes of the dielectric function are mapped in time-resolved measurements by a broadband THz probe pulse, which is detected in a phase-resolved way. …”
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Development of Time-Reversal Method for Impact Source Identification on Plate Structures by Chunlin Chen, Yulong Li, Fuh-Gwo Yuan

“…A number of parameters selected for determining the impact location, approximated transfer functions and steps taken for reconstructing the impact loading time-history are also examined. …”
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ParticleHolography.jl: Holographic particle measurement in Julia by Dai Nakai, Yohsuke Tanaka

“…This comprehensive software provides an end-to-end processing pipeline encompassing a wide range of functionalities: preprocessing, including background removal and camera calibration; three-dimensional reconstruction through diffraction calculations; particle analysis, including detection and tracking; and result visualization. …”
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“Cyclic nucleotides in plants: from obscure messengers to central regulators“ by Brygida Świeżawska-Boniecka, Adriana Szmidt-Jaworska

“…For decades, efforts to detect cyclic nucleotides, specifically cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), in plant tissues and to elucidate their functional roles were inconclusive. …”
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Keeping Active with Texting after Stroke (KATS): a single-arm feasibility and acceptability study of a behavioural intervention to promote community-based physical activity after s... by Gozde Ozakinci, Stephan U Dombrowski, Andrew Murphy, Albert Farre, Jenna Breckenridge, Jacqui H Morris, Linda A Irvine, Keith Jenkinson

“…Preintervention and postintervention measures provided preliminary information on step count, functional independence, mental well-being, self-efficacy and quality of life.Results 18 men and 13 women were recruited; three withdrew before intervention commencement. …”
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TET3-facilitated differentiation of human umbilical cord mesenchymal stem cells into oligodendrocyte precursor cells for spinal cord injury recovery by Yubo Zhang, Zhibin Peng, Man Guo, Yangyang Wang, Jingsong Liu, Yishu Liu, Mi Li, Tianli Wei, Pengfei Li, Yingwei Zhao, Yansong Wang

“…This study aimed to explore the TET3-mediated one-step induction of HUCMSCs into OPCs. Methods In vitro, HUCMSCs were induced into OPCs following TET3 overexpression. …”
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An AI-Based Open-Source Software for <i>Varroa</i> Mite Fall Analysis in Honeybee Colonies by Jesús Yániz, Matías Casalongue, Francisco Javier Martinez-de-Pison, Miguel Angel Silvestre, Beeguards Consortium, Pilar Santolaria, Jose Divasón

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GENERATION AND COLLECTION OF TOBACCO AEROSOL FOR SHISHA by N. N. Bubnova, M. V. Shkidyuk

“…Qualitative characteristics of tobacco aerosol for shisha are determined by the functional purpose and depend on the component composition of the tobacco mixture and the coal used.The purpose of the research is to develop a methodology for the comprehensive assessment of tobacco for shisha based on modern methods of product quality control and includes the following steps:- monitoring of the studies to determine the component composition of the hookah mixture and the aerosol produced;- analysis of hookah mixture testing modes and development of an aerosol generation protocol;- development of a method for collecting aerosol on a laboratory smoking machine; - quantitative analysis of toxic analytes by HPLC MS / MS method.Methods have been developed for the machine generation and collection of tobacco aerosol for hookah, taking into account low concentrations of the analyzed toxic substances.The expediency of using the HPLC MS / MS method to determine the quantity of the following substances in tobacco aerosol for shisha has been substantiated:- carbonyl compounds (formaldehyde, acetaldehyde, acrolein) by detection on an electrospray source in the negative polarity mode- tobacco specific nitrosoamines (NNN and NNK) by detection on an electrospray source in the positive polarity mode.During the research laboratory and analytical equipment was used: a five-channel linear CERULEAN SM 405 smoking machine; Thermo Scientific Dionex UltiMate 3000 liquid chromatograph and TSQ Quantiva mass spectrometer.Obtaining experimental data on the quantitative determination of the component composition of the aerosol produced by tobacco for shisha using hookah systems is relevant for assessing toxic characteristics of the product.…”
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Evaluation of microRNAs as liquid biopsy markers in adrenocortical tumors by Chrysoula Mytareli, Vassiliki Kalotychou, Alexandros Lafioniatis, Gregory Kaltsas, George N. Zografos, Athina Markou, Labrini Papanastasiou, Athanasios Fountas, Dimitra Argyro Vasilliadi, Evanthia Kassi, Evanthia Kassi, Marina Mantzourani, Anna Angelousi

“…IntroductionAdrenal tumors (ATs) encompass a wide differential diagnosis, necessitating a multi-step process for accurate identification. Liquid biopsy emerges as a promising non-invasive technique for distinguishing between malignant and benign, as well as hyperfunctioning and non-functioning cases. …”
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Features of Bone Mineral Density, Calcium-Phosphorus Metabolism and Bone Remodeling in Patients with Systemic Lupus Erythematosus by L. Tsyhanyk, O. Khuchlina, V. Ivachevska, N. Grechkivska, M. Panasiuk, L. Kobak

“…To achieve the stated goal, the first step included the determination of bone damage prevalence in patients with the diagnosed SLE; the second step was directed towards the characterization the particular bone condition in patients with SLE based on the results of BMD, CPM indices and markers of bone remodeling assessment. …”
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LABELING EXTRACELLULAR VESICLES FOR HIGHLY SENSITIVE FLOW CYTOMETRY ANALYSES

“…They cross all biological barriers and have been detected in all body fluids. For these reasons EVs are increasingly thought to be new potential dynamic biomarkers useful for liquid biopsy. …”
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Genome-wide analysis clarifies the population genetic structure of wild gilthead sea bream (Sparus aurata). by Francesco Maroso, Konstantinos Gkagkavouzis, Sabina De Innocentiis, Jasmien Hillen, Fernanda do Prado, Nikoleta Karaiskou, John Bernard Taggart, Adrian Carr, Einar Nielsen, Alexandros Triantafyllidis, Luca Bargelloni, Aquatrace Consortium

“…Seascape analysis suggested that this differentiation was mainly due to difference in salinity, this being also supported by preliminary genomic functional analysis. These results are of fundamental importance for the development of proper management of this species in the wild and are a first step toward the study of the potential genetic impact of the sea bream aquaculture industry.…”
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Properties of hydrolysates derived from the by-products of processing Atlantic cod by Naumenko N.V., Antonova A.D., Popova N.V., Kalinina I.V., Skachkova E.N.

“…To optimize this conventional method of production and improve the physicochemical and functional parameters of the resulting hydrolysate, ultrasound treatment has been proposed as a pre-treatment step. …”
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APAV: An advanced pangenome analysis and visualization toolkit. by Xiaorui Dong, Du Jiao, Hongzhang Xue, Shiyu Fan, Chaochun Wei

“…Additionally, the visual inspection of PAVs is an important but time-consuming step for pangenome analysis and result interpretation. …”
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A Hybrid Approach to Enhanced Signal Denoising Using Data-Driven Multiresolution Analysis with Detrended-Fluctuation-Analysis-Based Thresholding and Stationary Wavelet Transform by Fatima Kozhamkulova, Muhammad Tahir Akhtar

“…The proposed method first decomposes the signal into band-limited intrinsic mode functions (BLIMFs) using VMD. Then, a DFA-based developed metric is employed to identify the ‘noisy’ BLIMFs (based on their DFA-based scaling exponent and frequency content). …”
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