GzESTY as an optimized cell-based assay for initial steps in GPCR deorphanization by Luca Franchini, Joseph J. Porter, John D. Lueck, Cesare Orlandi

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One-Step Solvothermal Synthesis of Carbon Dots for Rapid and Accurate Determination of Hemin Content by Yiaobo Zhang, Lin Liu, Jiahui He, Chengzhi Huang, Lei Zhan, Chunmei Li

“…The as-prepared fluorescent CDs with rich functional groups on the surface displayed good water solubility, strong salt resistance, robust pH stability, and photobleaching resistance. …”
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One-Step Hydrothermal Synthesis of Multicolour Graphene Quantum Dots and Study of Their Luminescence Mechanism by Beibei Wang, Ling Sun, Kai Liu, Di Wu, Jinqiu Wang, Fang Geng

“…Multicolour graphene quantum dots (GQDs), from blue to orange emitting, were successfully synthesized via a one-step hydrothermal method using potassium hydrogen phthalate and o-phenylenediamine as the raw materials. …”
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Elastomeric Nanocomposite with Solvent‐Free, One Step, In Situ Shear Exfoliation of Graphite to Graphene by Ashiqur Rahman, Abdur Rahman Bin Abdus Salam, Matthew G. Boebinger, Ahmed Touhami, Jennifer Lynch, Ali Ashraf

“…The resulting intrinsic piezo resistivity of the fabricated nanocomposite has been exploited to fabricate a multi‐functional wired and wireless sensor for detecting different body movements, speech, human vital functions, solvents, and biomolecules.…”
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Enhanced thyroid nodule detection and diagnosis: a mobile-optimized DeepLabV3+ approach for clinical deployments by Changan Yang, Muhammad Awais Ashraf, Mudassar Riaz, Pascal Umwanzavugaye, Kavimbi Chipusu, Hongyuan Huang, Yueqin Xu

“…Data acquisition adhered to standardized protocols to ensure high-quality imaging. Preprocessing steps, including noise reduction and contrast optimization, were applied to enhance image clarity. …”
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A Step Forward in Long COVID Research: Validating the Post-COVID Cognitive Impairment Scale by Somayeh Pour Mohammadi, Razieh Etesamipour, Francisco Mercado Romero, Irene Peláez

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Data‐Driven Theoretical Modeling of Centrifugal Step Emulsification and Its Application in Comprehensive Multiscale Analysis by Xin Wang, Xiaolu Cai, Chao Wan, Huijuan Yuan, Shunji Li, Yiwei Zhang, Ran Zhao, Yuxi Qin, Yiwei Li, Bi‐Feng Liu, Peng Chen

“…This predictive model empowers the CASE to achieve all‐in‐one functionality, including droplet pre‐design, generation, manipulation, and on‐site detection. …”
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A New Approach Based on Metaheuristic Optimization Using Chaotic Functional Connectivity Matrices and Fractal Dimension Analysis for AI-Driven Detection of Orthodontic Growth and D... by Orhan Cicek, Yusuf Bahri Özçelik, Aytaç Altan

“…However, the nonlinear dynamics of these images pose significant challenges for reliable detection. This study presents a novel approach that integrates chaotic functional connectivity (FC) matrices and fractal dimension analysis to address these challenges. …”
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From tumor immunity to precision medicine: the next step in B7-H3/CD276 research by Fang Haolie, Liu Yuqian, Wang Gege, Liu Heng-Jia

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Framelet transform based edge detection for straight line detection from remote sensing images by Vidhya Rangasamy, Sulochana Subramaniam

“… Edge detection has been widely used as a pre-processing step for image processing applications such as region segmentation, feature extraction and object boundary description. …”
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Damage identification of structures using experimental modal analysis and continuous wavelet transform by A. Gholizad, H. Safari

“…EMA consists of three steps: data acquisition, system identification and modal parameter estimation. …”
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Solution of electromagnetic inverse problem of inhomogeneity reconstruction in dielectric body by near-field measurements using two-step method by Yury G. Smirnov, Andrey O. Lapich

“…The method of solving the inverse problem is a two-step one for determining the inhomogeneity of a body, which consists in first finding the current function inside the body, and then calculating the permittivity function. …”
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7-step endoscopic nipple-sparing mastectomy with implant-based breast reconstruction: nipple sensation preservation and low complications by Ze Huang, Zhijie Wu, Xiaoyan Fu, Yonghai Guo, Siyuan Lin, Jieying Chen, Zongyan Li, Zuxiao Chen, Haiyan Li

“…Methods The medical records of patients who received single-port E-NSM with IBBR guided by the seven-step method from January 2022 to March 2024 were analyzed. …”
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Oxygen systems to improve clinical care and outcomes for children and neonates: A stepped-wedge cluster-randomised trial in Nigeria. by Hamish R Graham, Ayobami A Bakare, Adejumoke I Ayede, Amy Z Gray, Barbara McPake, David Peel, Olatayo Olatinwo, Oladapo B Oyewole, Eleanor F G Neal, Cattram D Nguyen, Shamim A Qazi, Rasa Izadnegahdar, John B Carlin, Adegoke G Falade, Trevor Duke

“…Limitations of our study are a lower-than-anticipated power to detect change in mortality outcomes (low event rates, low participant numbers, high intracluster correlation) and major contextual changes related to the 2016-2017 Nigerian economic recession that influenced care-seeking and hospital function during the study period, potentially confounding mortality outcomes.…”
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Actionable Wearables Data for the Neurology Clinic: A Proof‐of‐Concept Tool by Nicolette Miller, Ebenezer Chinedu‐Eneh, Jaeleene Wijangco, Kyra Henderson, Nikki Sisodia, Narender Sara, Jennifer Reihm, Shane Poole, Jim Rowson, Chu‐Yueh Guo, Jeffrey M. Gelfand, Valerie J. Block, Riley Bove

“…In multiple sclerosis (MS), monitoring step count and sleep is feasible, valid, and offers a holistic glimpse of patient functioning and worsening. …”
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A robust in-vitro and ex-vitro Agrobacterium rhizogenes-mediated hairy root transformation system in mungbean for efficient visual screening of transformants using the RUBY reporte... by Sanjeev Kumar, Sakshi Prakash, Priti Kumari, Neeti Sanan-Mishra

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Finding process-behavioural parameterisations of a hydrological model using a multi-step process-based calibration and evaluation scheme by M. M. Heuer, H. Mohajerani, M. C. Casper

“…We were also able to detect the model parameterisations based on the PTFs that showed satisfactory results across all calibration steps. …”
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On the utility function of experiments in fundamental science by Tommaso Dorigo, Michele Doro, Max Aehle, Muhammad Awais, Nicolas R. Gauger, Rafael Izbicki, Jan Kieseler, Ann B. Lee, Luca Masserano, Federico Nardi, Alexander Shen, Luis Recabarren Vergara

“…Most of the time, a combination of the above goals is pursued; this breadth of scope adds a layer of complexity to the already demanding task of designing the measurement apparatus in an optimal way, by defining suitable geometries and choosing the most advantageous materials and appropriate detection technologies. The precise definition of a global optimality criterion may then require experimentalists to find a consensus on the relative scientific worth of those goals.In this work we discuss the problem of formulating a utility function for multipurpose experiments, as an enabling step to employ artificial intelligence tools to explore the design space and assist humans in finding solutions at the Pareto front. …”
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Methodology of adipose tissue type detection in mammals by I. M. Chernukha, N. V. Kupaeva, J. A. Smirnova, A. G. Akhremko, V. A. Pchelkina, E. A. Kotenkova

“…In this connection, the aim of this research was to develop a methodological approach allowing rapid and effective detection of an adipose tissue type. A methodology was formed based on the concept, formalized requirements for the method, step-wise structure of investigations and interpretation of results. …”
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Hybrid metaheuristic optimization for detecting and diagnosing noncommunicable diseases by Saleem Malik, S. Gopal Krishna Patro, Chandrakanta Mahanty, Saravanapriya Kumar, Ayodele Lasisi, Quadri Noorulhasan Naveed, Anjanabhargavi Kulkarni, Abdulrajak Buradi, Addisu Frinjo Emma, Naoufel Kraiem

“…The proposed framework presents a significant step towards enhancing the early detection and management of NCDs, offering hope for more precise clinical predictions and improved patient care.…”
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